DK1377298T3 - Exemestan til behandling af hormon-afhængige lidelser - Google Patents
Exemestan til behandling af hormon-afhængige lidelserInfo
- Publication number
- DK1377298T3 DK1377298T3 DK02727314T DK02727314T DK1377298T3 DK 1377298 T3 DK1377298 T3 DK 1377298T3 DK 02727314 T DK02727314 T DK 02727314T DK 02727314 T DK02727314 T DK 02727314T DK 1377298 T3 DK1377298 T3 DK 1377298T3
- Authority
- DK
- Denmark
- Prior art keywords
- exemestane
- hormone
- treatment
- dependent disorders
- disorders
- Prior art date
Links
- BFYIZQONLCFLEV-DAELLWKTSA-N Aromasine Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=C)C2=C1 BFYIZQONLCFLEV-DAELLWKTSA-N 0.000 title 1
- 230000001419 dependent effect Effects 0.000 title 1
- 229960000255 exemestane Drugs 0.000 title 1
- 229940088597 hormone Drugs 0.000 title 1
- 239000005556 hormone Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77091101A | 2001-01-26 | 2001-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1377298T3 true DK1377298T3 (da) | 2007-01-02 |
Family
ID=25090093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02727314T DK1377298T3 (da) | 2001-01-26 | 2002-01-18 | Exemestan til behandling af hormon-afhængige lidelser |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1377298B1 (da) |
| JP (1) | JP2004519490A (da) |
| AR (1) | AR032268A1 (da) |
| AT (1) | ATE337787T1 (da) |
| CA (1) | CA2434611A1 (da) |
| DE (1) | DE60214355T2 (da) |
| DK (1) | DK1377298T3 (da) |
| ES (1) | ES2269682T3 (da) |
| MX (1) | MXPA03006607A (da) |
| PE (1) | PE20020843A1 (da) |
| PT (1) | PT1377298E (da) |
| WO (1) | WO2002072106A2 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040053900A1 (en) * | 1998-12-23 | 2004-03-18 | Pharmacia Corporation | Method of using a COX-2 inhibitor and an aromatase inhibitor as a combination therapy |
| WO2003017973A1 (en) * | 2001-08-31 | 2003-03-06 | Pantarhei Bioscience B.V. | A method of treating benign gynaecological disorders and a drug delivery vehicle for use in such a method |
| GB0302572D0 (en) | 2003-02-05 | 2003-03-12 | Astrazeneca Ab | Method of treatment |
| RU2227035C1 (ru) * | 2003-02-05 | 2004-04-20 | Павловский Алексей Васильевич | Состав для профилактики и лечения фиброзно-кистозной мастопатии |
| EP1638573A4 (en) * | 2003-06-20 | 2009-12-02 | Merck & Co Inc | USE OF SELECTIVE CYCLOOXYGENASE-2 INHIBITORS FOR THE TREATMENT OF ENDOMETRIOSIS |
| WO2007062093A2 (en) * | 2005-11-22 | 2007-05-31 | Incyte Corporation | Combination therapy for the treatment of cancer comprising a metalloprotease inhibitor |
| AU2007230716B2 (en) | 2006-03-28 | 2012-05-03 | Javelin Pharmaceuticals, Inc. | Formulations of low dose diclofenac and beta-cyclodextrin |
| WO2008019048A1 (en) * | 2006-08-04 | 2008-02-14 | Meditrina Pharmaceuticals | Use of aromatase inhibitors for thining the endometrium or treating menorrhagia |
| RU2357733C1 (ru) * | 2008-03-04 | 2009-06-10 | Ольга Анатольевна Тихоновская | Способ лечения функциональных кист яичников |
| CN101717393A (zh) * | 2009-12-01 | 2010-06-02 | 陈依军 | 环己基2,5-二取代苯基醚的衍生物及其应用 |
| DE102010003494A1 (de) * | 2010-03-31 | 2011-10-06 | Bayer Schering Pharma Aktiengesellschaft | Parenterales Abgabesystem, das Aromatasehemmer und Gestagene freisetzt, für die Behandlung von Endometriose |
| HUE033581T2 (hu) | 2010-06-10 | 2017-12-28 | Seragon Pharmaceuticals Inc | Ösztrogén receptor modulátorok és alkalmazásaik |
| SG11201403002RA (en) | 2011-12-14 | 2014-07-30 | Seragon Pharmaceuticals Inc | Fluorinated estrogen receptor modulators and uses thereof |
| EP3050878B1 (en) | 2013-09-24 | 2021-10-27 | FUJIFILM Corporation | Novel nitrogen-containing compound or salt thereof, or metal complex thereof |
| AU2016381336A1 (en) | 2015-12-30 | 2018-06-28 | Saint Louis University | Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists |
| CN113712974B (zh) * | 2021-08-20 | 2025-09-09 | 南京大学 | 阿司匹林作为唯一活性成分在制备治疗子宫内膜增生药物中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8517360D0 (en) * | 1985-07-09 | 1985-08-14 | Erba Farmitalia | Substituted androsta-1,4-diene-3,17-diones |
| GB8617107D0 (en) * | 1986-07-14 | 1986-08-20 | Erba Farmitalia | 6-/7-methylenandrosta-1 4-diene-3 17-dione derivatives |
| WO1994019365A1 (en) * | 1993-02-18 | 1994-09-01 | Farmitalia Carlo Erba Srl | Fluorinated 4-aminoandrostadienone derivatives and process for their preparation |
| GB9313420D0 (en) * | 1993-06-29 | 1993-08-11 | Erba Carlo Spa | Fluorinated 6-methylenandrosta-1,4-dien-3-one-derivatives and process for their preparations |
| CN1398189A (zh) * | 1998-12-23 | 2003-02-19 | G.D.西尔公司 | 用于治疗肿瘤形成的放疗与cox－2抑制剂的联合治疗 |
| AU784617B2 (en) * | 2000-05-15 | 2006-05-18 | Pharmacia & Upjohn Company | Aromatase inhibitors and monoclonal anti-HER2 antibodies as antitumors agents |
| EP1317270A1 (en) * | 2000-09-08 | 2003-06-11 | Pharmacia Italia S.p.A. | Exemestane for the treatment of oestrogen-dependent cancers |
-
2002
- 2002-01-18 CA CA002434611A patent/CA2434611A1/en not_active Abandoned
- 2002-01-18 JP JP2002571065A patent/JP2004519490A/ja not_active Withdrawn
- 2002-01-18 DE DE60214355T patent/DE60214355T2/de not_active Expired - Fee Related
- 2002-01-18 MX MXPA03006607A patent/MXPA03006607A/es not_active Application Discontinuation
- 2002-01-18 EP EP02727314A patent/EP1377298B1/en not_active Expired - Lifetime
- 2002-01-18 PT PT02727314T patent/PT1377298E/pt unknown
- 2002-01-18 WO PCT/EP2002/000638 patent/WO2002072106A2/en not_active Ceased
- 2002-01-18 ES ES02727314T patent/ES2269682T3/es not_active Expired - Lifetime
- 2002-01-18 DK DK02727314T patent/DK1377298T3/da active
- 2002-01-18 AT AT02727314T patent/ATE337787T1/de not_active IP Right Cessation
- 2002-01-23 PE PE2002000050A patent/PE20020843A1/es not_active Application Discontinuation
- 2002-01-24 AR ARP020100236A patent/AR032268A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002072106A3 (en) | 2003-10-30 |
| ATE337787T1 (de) | 2006-09-15 |
| DE60214355T2 (de) | 2007-08-30 |
| EP1377298A2 (en) | 2004-01-07 |
| EP1377298B1 (en) | 2006-08-30 |
| AR032268A1 (es) | 2003-10-29 |
| DE60214355D1 (de) | 2006-10-12 |
| WO2002072106A2 (en) | 2002-09-19 |
| JP2004519490A (ja) | 2004-07-02 |
| PT1377298E (pt) | 2006-12-29 |
| MXPA03006607A (es) | 2003-09-22 |
| ES2269682T3 (es) | 2007-04-01 |
| PE20020843A1 (es) | 2002-09-25 |
| CA2434611A1 (en) | 2002-09-19 |
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