DK1711530T3 - Nogo-A-neutraliserende immunoglobuliner til behandling af neurologiske sygdomme - Google Patents

Nogo-A-neutraliserende immunoglobuliner til behandling af neurologiske sygdomme

Info

Publication number: DK1711530T3
Authority: DK; Denmark
Prior art keywords: nogo; treatment; neurological disorders; neutralizing immunoglobulins; immunoglobulins
Prior art date: 2003-12-22

Application number

DK04806128T

Other languages

English (en)

Inventor

Jonathan Henry Ellis

Farhana Hussain

Ruth Mcadam

Christopher Plumpton

Rabinder Kumar Prinjha

Paul Alexander Wilson

Alexandre Eon-Duval

Robert Ian Grundy

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-22

Filing date

2004-12-20

Publication date

2009-12-14

2003-12-22 Priority claimed from GB0329684A external-priority patent/GB0329684D0/en

2003-12-22 Priority claimed from GB0329711A external-priority patent/GB0329711D0/en

2004-12-20 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2009-12-14 Application granted granted Critical

2009-12-14 Publication of DK1711530T3 publication Critical patent/DK1711530T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Wood Science & Technology (AREA)
Veterinary Medicine (AREA)
Biotechnology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Immunology (AREA)
Microbiology (AREA)
Cell Biology (AREA)
General Engineering & Computer Science (AREA)
Psychology (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Hospice & Palliative Care (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK04806128T 2003-12-22 2004-12-20 Nogo-A-neutraliserende immunoglobuliner til behandling af neurologiske sygdomme DK1711530T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0329684A GB0329684D0 (en)	2003-12-22	2003-12-22	Method
GB0329711A GB0329711D0 (en)	2003-12-22	2003-12-22	Antibodies
PCT/GB2004/005325 WO2005061544A2 (en)	2003-12-22	2004-12-20	Nogo-a neutralising immunoglobulins for treatment of neurological diseases

Publications (1)

Publication Number	Publication Date
DK1711530T3 true DK1711530T3 (da)	2009-12-14

Family

ID=34712703

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04806128T DK1711530T3 (da)	2003-12-22	2004-12-20	Nogo-A-neutraliserende immunoglobuliner til behandling af neurologiske sygdomme

Country Status (27)

Country	Link
US (4)	US7988964B2 (da)
EP (3)	EP1706426A2 (da)
JP (2)	JP4901480B2 (da)
KR (1)	KR101150548B1 (da)
AR (1)	AR048912A1 (da)
AT (1)	ATE440866T1 (da)
AU (1)	AU2004303585B2 (da)
BR (1)	BRPI0417959A (da)
CA (1)	CA2549956C (da)
CY (1)	CY1110530T1 (da)
DE (1)	DE602004022871D1 (da)
DK (1)	DK1711530T3 (da)
ES (1)	ES2330444T3 (da)
HR (1)	HRP20090527T1 (da)
IL (1)	IL176206A (da)
IS (1)	IS2739B (da)
MA (1)	MA28289A1 (da)
MX (1)	MXPA06007190A (da)
MY (1)	MY144612A (da)
NO (1)	NO20062767L (da)
NZ (1)	NZ548013A (da)
PL (1)	PL1711530T3 (da)
PT (1)	PT1711530E (da)
RU (1)	RU2362780C2 (da)
SI (1)	SI1711530T1 (da)
TW (1)	TWI329649B (da)
WO (2)	WO2005061544A2 (da)

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GB0321997D0 (en) *	2003-09-19	2003-10-22	Novartis Ag	Organic compound
NZ548013A (en)	2003-12-22	2009-04-30	Glaxo Group Ltd	Immunoglobulins
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CA2704357C (en)	2007-11-02	2016-06-21	Novartis Ag	Improved nogo-a binding molecules and pharmaceutical use thereof
US8962803B2 (en)	2008-02-29	2015-02-24	AbbVie Deutschland GmbH & Co. KG	Antibodies against the RGM A protein and uses thereof
EA201001603A1 (ru) *	2008-04-04	2011-06-30	Те Риджентс Оф Те Юниверсити Оф Калифорния	Антитела против кадгерина, блокирующие рост опухоли, ангиогенез и метастазирование
CA2730473A1 (en) *	2008-07-11	2010-01-14	Glaxo Group Limited	Novel treatment
US10266585B2 (en)	2009-08-28	2019-04-23	The Board Of Regents Of The Univerity Of Texas System	Methods of treating brain injury
PH12012501070A1 (en)	2009-12-08	2017-08-23	Abbott Gmbh & Co Kg	Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
WO2011130377A2 (en)	2010-04-15	2011-10-20	Abbott Laboratories	Amyloid-beta binding proteins
US8828390B2 (en)	2010-07-09	2014-09-09	Universitat Zurich	Uses of NOGO-A inhibitors and related methods
US9062101B2 (en)	2010-08-14	2015-06-23	AbbVie Deutschland GmbH & Co. KG	Amyloid-beta binding proteins
CA2817973C (en)	2010-10-15	2019-06-25	The Board Of Regents Of The University Of Texas System	Antibodies that bind amyloid oligomers
CA2815277A1 (en)	2010-10-29	2012-05-03	Immunogen, Inc.	Novel egfr-binding molecules and immunoconjugates thereof
JP5828902B2 (ja)	2010-10-29	2015-12-09	イミュノジェン，インコーポレイテッド	非拮抗性ｅｇｆｒ結合分子およびその免疫複合体
JP2014533954A (ja)	2011-11-21	2014-12-18	イミュノジェン，インコーポレイテッド	Ｅｇｆｒ抗体細胞傷害性薬物複合体による、ｅｇｆｒ療法に耐性である腫瘍の治療方法
US20140050720A1 (en)	2012-01-09	2014-02-20	The Scripps Research Institute	Ultralong complementarity determining regions and uses thereof
AU2013211939C1 (en)	2012-01-27	2018-06-07	AbbVie Deutschland GmbH & Co. KG	Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
IN2014KN02952A (da)	2012-07-05	2015-05-08	Glaxo Group Ltd
BR112017023872A2 (pt)	2015-05-04	2018-07-24	Cytomx Therapeutics Inc	anticorpos anti-cd166, anticorpos anti-cd166 ativáveis e métodos de uso dos mesmos
US20180362660A1 (en) *	2016-05-09	2018-12-20	Schickwann Tsai	Anti-penumbra monoclonal antibodies for detection and therapy of normal and abnormal B lymphocytes
US11220544B2 (en) *	2017-07-14	2022-01-11	Cytomx Therapeutics, Inc.	Anti-CD166 antibodies and uses thereof
TW201946654A (zh)	2018-03-05	2019-12-16	比利時商健生藥品公司	抗ＰＨＦ－Ｔａｕ抗體及其用途
JP2022501319A (ja) *	2018-09-25	2022-01-06	アカデミアシニカAcademia Sinica	抗Ｓｉｇｌｅｃ抗体、それを備える薬学的組成物及びその使用
BR112022006534A2 (pt)	2019-10-24	2022-07-05	Novago Therapeutics Ag	Anticorpos anti-nogo-a
CN116635718A (zh) *	2020-12-02	2023-08-22	安捷伦科技有限公司	用于在免疫组织化学（ihc）方案中使用以诊断癌症的抗人cd10抗体
WO2024041450A1 (zh) *	2022-08-22	2024-02-29	舒泰神（北京）生物制药股份有限公司	特异性识别Nogo-A的抗体及其应用
CN116693672B (zh) *	2023-06-15	2025-08-08	郑州伊美诺生物技术有限公司	抗3型人副流感病毒单克隆抗体及其制备方法和应用
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2004
- 2004-12-20 NZ NZ548013A patent/NZ548013A/en not_active IP Right Cessation
- 2004-12-20 JP JP2006544554A patent/JP4901480B2/ja not_active Expired - Fee Related
- 2004-12-20 EP EP04806145A patent/EP1706426A2/en not_active Withdrawn
- 2004-12-20 ES ES04806128T patent/ES2330444T3/es not_active Expired - Lifetime
- 2004-12-20 AU AU2004303585A patent/AU2004303585B2/en not_active Ceased
- 2004-12-20 AT AT04806128T patent/ATE440866T1/de active
- 2004-12-20 HR HR20090527T patent/HRP20090527T1/xx unknown
- 2004-12-20 WO PCT/GB2004/005325 patent/WO2005061544A2/en not_active Ceased
- 2004-12-20 AR ARP040104811A patent/AR048912A1/es not_active Application Discontinuation
- 2004-12-20 EP EP04806128A patent/EP1711530B1/en not_active Expired - Lifetime
- 2004-12-20 WO PCT/GB2004/005343 patent/WO2005061545A2/en not_active Ceased
- 2004-12-20 DK DK04806128T patent/DK1711530T3/da active
- 2004-12-20 KR KR1020067014806A patent/KR101150548B1/ko not_active Expired - Fee Related
- 2004-12-20 MY MYPI20045254A patent/MY144612A/en unknown
- 2004-12-20 MX MXPA06007190A patent/MXPA06007190A/es active IP Right Grant
- 2004-12-20 SI SI200431272T patent/SI1711530T1/sl unknown
- 2004-12-20 DE DE602004022871T patent/DE602004022871D1/de not_active Expired - Lifetime
- 2004-12-20 US US10/583,877 patent/US7988964B2/en not_active Expired - Fee Related
- 2004-12-20 JP JP2006546307A patent/JP2007537145A/ja active Pending
- 2004-12-20 CA CA2549956A patent/CA2549956C/en not_active Expired - Fee Related
- 2004-12-20 TW TW093139709A patent/TWI329649B/zh not_active IP Right Cessation
- 2004-12-20 PL PL04806128T patent/PL1711530T3/pl unknown
- 2004-12-20 EP EP09168234A patent/EP2213684A3/en not_active Withdrawn
- 2004-12-20 RU RU2006123481/13A patent/RU2362780C2/ru not_active IP Right Cessation
- 2004-12-20 BR BRPI0417959-5A patent/BRPI0417959A/pt not_active IP Right Cessation
- 2004-12-20 PT PT04806128T patent/PT1711530E/pt unknown
2005
- 2005-07-06 US US11/177,648 patent/US7780964B2/en not_active Expired - Fee Related
2006
- 2006-06-08 IL IL176206A patent/IL176206A/en not_active IP Right Cessation
- 2006-06-12 IS IS8506A patent/IS2739B/is unknown
- 2006-06-13 NO NO20062767A patent/NO20062767L/no not_active Application Discontinuation
- 2006-07-10 MA MA29178A patent/MA28289A1/fr unknown
2009
- 2009-11-11 CY CY20091101175T patent/CY1110530T1/el unknown
2010
- 2010-08-23 US US12/861,205 patent/US20110054149A1/en not_active Abandoned
2013
- 2013-05-07 US US13/888,764 patent/US20140147435A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20110054149A1 (en)	2011-03-03
WO2005061545A2 (en)	2005-07-07
EP2213684A3 (en)	2011-05-18
IS2739B (is)	2011-06-15
CY1110530T1 (el)	2015-04-29
KR101150548B1 (ko)	2012-07-06
AR048912A1 (es)	2006-06-14
HRP20090527T1 (hr)	2009-11-30
EP1711530A2 (en)	2006-10-18
JP2007537145A (ja)	2007-12-20
BRPI0417959A (pt)	2007-03-27
TW200533680A (en)	2005-10-16
CA2549956C (en)	2016-04-12
ATE440866T1 (de)	2009-09-15
US20140147435A1 (en)	2014-05-29
DE602004022871D1 (de)	2009-10-08
WO2005061544A2 (en)	2005-07-07
US20060029603A1 (en)	2006-02-09
JP4901480B2 (ja)	2012-03-21
CA2549956A1 (en)	2005-07-07
IL176206A0 (en)	2006-10-05
ES2330444T3 (es)	2009-12-10
MY144612A (en)	2011-10-14
MA28289A1 (fr)	2006-11-01
HK1100144A1 (en)	2007-09-07
TWI329649B (en)	2010-09-01
SI1711530T1 (sl)	2010-01-29
US20070065430A1 (en)	2007-03-22
EP1706426A2 (en)	2006-10-04
IL176206A (en)	2012-02-29
US7780964B2 (en)	2010-08-24
AU2004303585B2 (en)	2010-12-23
PL1711530T3 (pl)	2010-01-29
US7988964B2 (en)	2011-08-02
NO20062767L (no)	2006-09-20
RU2362780C2 (ru)	2009-07-27
WO2005061544A3 (en)	2005-08-18
IS8506A (is)	2006-06-12
PT1711530E (pt)	2009-10-22
RU2006123481A (ru)	2008-01-27
JP2008504220A (ja)	2008-02-14
WO2005061545A3 (en)	2005-08-18
EP2213684A2 (en)	2010-08-04
EP1711530B1 (en)	2009-08-26
NZ548013A (en)	2009-04-30
MXPA06007190A (es)	2006-08-23
AU2004303585A1 (en)	2005-07-07
KR20060129290A (ko)	2006-12-15

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