DK1383603T3 - Fremgangsmåde til accelerering og intensivering af målreceptorbinding og indretning dertil - Google Patents
Fremgangsmåde til accelerering og intensivering af målreceptorbinding og indretning dertilInfo
- Publication number
- DK1383603T3 DK1383603T3 DK02732596T DK02732596T DK1383603T3 DK 1383603 T3 DK1383603 T3 DK 1383603T3 DK 02732596 T DK02732596 T DK 02732596T DK 02732596 T DK02732596 T DK 02732596T DK 1383603 T3 DK1383603 T3 DK 1383603T3
- Authority
- DK
- Denmark
- Prior art keywords
- substrate
- binding
- shear
- field generating
- target molecules
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
- B01F25/4317—Profiled elements, e.g. profiled blades, bars, pillars, columns or chevrons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
- B01F25/43197—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor characterised by the mounting of the baffles or obstructions
- B01F25/431971—Mounted on the wall
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/29—Mixing by periodically deforming flexible tubular members through which the material is flowing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/30—Mixers with shaking, oscillating, or vibrating mechanisms comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted
- B01F31/31—Mixers with shaking, oscillating, or vibrating mechanisms comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted using receptacles with deformable parts, e.g. membranes, to which a motion is imparted
- B01F31/311—Mixers with shaking, oscillating, or vibrating mechanisms comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted using receptacles with deformable parts, e.g. membranes, to which a motion is imparted the motion being a linear movement to one part of the receptacle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/50—Mixing receptacles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
- G01N30/92—Construction of the plate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0812—Bands; Tapes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Clinical Laboratory Science (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Discharge Heating (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01870091 | 2001-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1383603T3 true DK1383603T3 (da) | 2007-01-02 |
Family
ID=8184962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02732596T DK1383603T3 (da) | 2001-04-26 | 2002-04-11 | Fremgangsmåde til accelerering og intensivering af målreceptorbinding og indretning dertil |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040171002A1 (de) |
| EP (2) | EP1627686A1 (de) |
| JP (1) | JP2004536694A (de) |
| AT (1) | ATE337094T1 (de) |
| CY (1) | CY1105742T1 (de) |
| DE (1) | DE60214155T2 (de) |
| DK (1) | DK1383603T3 (de) |
| ES (1) | ES2271256T3 (de) |
| PT (1) | PT1383603E (de) |
| WO (1) | WO2002087761A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE337094T1 (de) * | 2001-04-26 | 2006-09-15 | Univ Bruxelles | Verfahren zur beschleunigung und verstärkung der bindung von zielkomponenten an rezeptoren und vorrichtung dafür |
| JP5016638B2 (ja) * | 2003-05-09 | 2012-09-05 | 日立アロカメディカル株式会社 | 処理装置 |
| JP2004357698A (ja) * | 2003-05-09 | 2004-12-24 | Aloka Co Ltd | 処理装置 |
| JP2007522913A (ja) * | 2003-10-03 | 2007-08-16 | フリーイェ・ユニヴェルシテイト・ブリュッセル | 流体中に存在する粒子を粒度分離するための方法及び装置 |
| JP4814103B2 (ja) * | 2003-11-12 | 2011-11-16 | バイオ−ラッド・ハイファ・リミテッド | アレイフォーマットにおいて複数の結合反応を実行するためのシステムおよび方法 |
| DE10354806A1 (de) * | 2003-11-21 | 2005-06-02 | Boehringer Ingelheim Microparts Gmbh | Probenträger |
| JP4441599B2 (ja) * | 2005-01-12 | 2010-03-31 | 多摩川精機株式会社 | 蛋白質スクリーニング装置 |
| WO2007072373A2 (en) * | 2005-12-21 | 2007-06-28 | Koninklijke Philips Electronics N.V. | A sensor for biomolecules and a method of analysis using said sensor |
| WO2007105140A2 (en) * | 2006-03-15 | 2007-09-20 | Koninklijke Philips Electronics N. V. | Microelectronic device with controllable reference substance supply |
| WO2008055096A2 (en) | 2006-10-30 | 2008-05-08 | Ventana Medical Systems, Inc. | Thin film apparatus and method |
| EP1944080A1 (de) * | 2007-01-11 | 2008-07-16 | F.Hoffmann-La Roche Ag | Vorrichtung und Verfahren zum Bewegen einer Flüssigkeit in einer Kavität |
| DE102008010436A1 (de) * | 2008-02-21 | 2009-09-03 | Berthold Technologies Gmbh & Co. Kg | Vorrichtung und Verfahren zur Messung von Lumineszenz und Fluoreszenz von transfizierten Zellen oder Organteilen |
| US8221985B2 (en) | 2008-04-02 | 2012-07-17 | Abbott Point Of Care, Inc. | Self-calibrating gradient dilution in a constituent assay and gradient dilution apparatus performed in a thin film sample |
| US20100075863A1 (en) * | 2008-09-25 | 2010-03-25 | Northrop Grumman Systems Corporation | Rotary array module for multiplexing spot-based optical readouts |
| WO2014150853A1 (en) * | 2013-03-15 | 2014-09-25 | Inanovate, Inc. | Analyte measurement using longitudinal assay |
| KR101817122B1 (ko) * | 2015-12-14 | 2018-01-10 | 경희대학교 산학협력단 | 분자 통신 시스템, 분자 통신 방법, 분자 송신기 및 분자 수신기 |
| US11499962B2 (en) | 2017-11-17 | 2022-11-15 | Ultima Genomics, Inc. | Methods and systems for analyte detection and analysis |
| US12239980B2 (en) * | 2018-12-07 | 2025-03-04 | Ultima Genomics, Inc. | Implementing barriers for controlled environments during sample processing and detection |
| US11118223B2 (en) | 2019-03-14 | 2021-09-14 | Ultima Genomics, Inc. | Methods, devices, and systems for analyte detection and analysis |
| US10900078B2 (en) | 2019-03-14 | 2021-01-26 | Ultima Genomics, Inc. | Methods, devices, and systems for analyte detection and analysis |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3587885T2 (de) * | 1984-03-21 | 1994-11-03 | Mclaughlin William F | Filtration einer flüssigen Suspension. |
| US4874507A (en) * | 1986-06-06 | 1989-10-17 | Whitlock David R | Separating constituents of a mixture of particles |
| DE4108820A1 (de) * | 1991-03-18 | 1992-09-24 | Karl Dr Reuter | Kontinuierliche chromatographie |
| US6017696A (en) * | 1993-11-01 | 2000-01-25 | Nanogen, Inc. | Methods for electronic stringency control for molecular biological analysis and diagnostics |
| IL106330A (en) * | 1993-07-14 | 1998-01-04 | Univ Ramot | Method and instrument for determining the activity of their plaques in the initial coagulation system |
| EP0670489A3 (de) * | 1994-03-03 | 1996-03-06 | Ciba Geigy Ag | Vorrichtung und Verfahren zur Trennung fluider Substanzen. |
| EP0882982A1 (de) * | 1997-06-04 | 1998-12-09 | Vrije Universiteit Brussel | Verfahren und Vorrichtung zur Trennung eines Fluids |
| CA2333391C (en) * | 1998-05-25 | 2012-01-31 | Herbert Peter Jennissen | Flow-through shear analyzer for biologically active molecules in liquid layers on surfaces |
| ATE337094T1 (de) * | 2001-04-26 | 2006-09-15 | Univ Bruxelles | Verfahren zur beschleunigung und verstärkung der bindung von zielkomponenten an rezeptoren und vorrichtung dafür |
-
2002
- 2002-04-11 AT AT02732596T patent/ATE337094T1/de not_active IP Right Cessation
- 2002-04-11 ES ES02732596T patent/ES2271256T3/es not_active Expired - Lifetime
- 2002-04-11 DE DE60214155T patent/DE60214155T2/de not_active Expired - Fee Related
- 2002-04-11 WO PCT/EP2002/004034 patent/WO2002087761A1/en not_active Ceased
- 2002-04-11 EP EP05024473A patent/EP1627686A1/de not_active Withdrawn
- 2002-04-11 US US10/474,284 patent/US20040171002A1/en not_active Abandoned
- 2002-04-11 PT PT02732596T patent/PT1383603E/pt unknown
- 2002-04-11 EP EP02732596A patent/EP1383603B1/de not_active Expired - Lifetime
- 2002-04-11 DK DK02732596T patent/DK1383603T3/da active
- 2002-04-11 JP JP2002585095A patent/JP2004536694A/ja active Pending
-
2005
- 2005-10-28 US US11/262,319 patent/US20060078934A1/en not_active Abandoned
-
2006
- 2006-10-31 CY CY20061101558T patent/CY1105742T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002087761A1 (en) | 2002-11-07 |
| DE60214155T2 (de) | 2007-07-19 |
| ES2271256T3 (es) | 2007-04-16 |
| PT1383603E (pt) | 2007-01-31 |
| US20040171002A1 (en) | 2004-09-02 |
| EP1627686A1 (de) | 2006-02-22 |
| EP1383603B1 (de) | 2006-08-23 |
| EP1383603A1 (de) | 2004-01-28 |
| JP2004536694A (ja) | 2004-12-09 |
| US20060078934A1 (en) | 2006-04-13 |
| CY1105742T1 (el) | 2010-12-22 |
| DE60214155D1 (de) | 2006-10-05 |
| ATE337094T1 (de) | 2006-09-15 |
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