DK1397380T3 - Multipelt antigent peptid, der udviser flere kopier af en epitop af et plaquedannende polypeptid, og fremgangmåder til anvendelse deraf - Google Patents

Multipelt antigent peptid, der udviser flere kopier af en epitop af et plaquedannende polypeptid, og fremgangmåder til anvendelse deraf

Info

Publication number: DK1397380T3
Authority: DK; Denmark
Prior art keywords: plaque; epitope; forming polypeptide; methods; antigenic peptide
Prior art date: 2001-06-20

Application number

DK02737552T

Other languages

Danish (da)

English (en)

Inventor

Beka Solomon

Original Assignee

Univ Ramot

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-20

Filing date

2002-06-20

Publication date

2007-05-07

2002-06-20 Application filed by Univ Ramot filed Critical Univ Ramot

2007-05-07 Application granted granted Critical

2007-05-07 Publication of DK1397380T3 publication Critical patent/DK1397380T3/da

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
230000000890 antigenic effect Effects 0.000 title abstract 5
229920001184 polypeptide Polymers 0.000 title abstract 4
102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
230000001747 exhibiting effect Effects 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
201000010099 disease Diseases 0.000 abstract 2
230000028993 immune response Effects 0.000 abstract 2
102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
230000003053 immunization Effects 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
- A61K2039/645—Dendrimers; Multiple antigen peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Neurology (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK02737552T 2001-06-20 2002-06-20 Multipelt antigent peptid, der udviser flere kopier af en epitop af et plaquedannende polypeptid, og fremgangmåder til anvendelse deraf DK1397380T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US29920101P	2001-06-20	2001-06-20
US37171702P	2002-04-12	2002-04-12
PCT/US2002/019567 WO2003000719A2 (en)	2001-06-20	2002-06-20	Multiple antigenic peptide displaying multiple copies of an epitope of plaque-forming polypeptide and methods of using same

Publications (1)

Publication Number	Publication Date
DK1397380T3 true DK1397380T3 (da)	2007-05-07

Family

ID=26971089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02737552T DK1397380T3 (da)	2001-06-20	2002-06-20	Multipelt antigent peptid, der udviser flere kopier af en epitop af et plaquedannende polypeptid, og fremgangmåder til anvendelse deraf

Country Status (10)

Country	Link
US (1)	US20050053575A1 (de)
EP (1)	EP1397380B1 (de)
AT (1)	ATE349468T1 (de)
AU (1)	AU2002310474A1 (de)
CA (1)	CA2450783A1 (de)
DE (1)	DE60217107T2 (de)
DK (1)	DK1397380T3 (de)
ES (1)	ES2279869T3 (de)
PT (1)	PT1397380E (de)
WO (1)	WO2003000719A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2392247T3 (es)	2002-03-05	2012-12-07	Ramot At Tel-Aviv University Ltd.	Compuesto inmunizante y método para inducir una respuesta inmune contra el sitio de escisión de la beta-secretasa de la proteína precursora de amiloide
EP1523499A2 (de) *	2002-07-24	2005-04-20	Innogenetics N.V.	Fragmente von beta-amyloid als angriffspunkt einer impfung gegen alzheimersche krankheit
US8663650B2 (en)	2003-02-21	2014-03-04	Ac Immune Sa	Methods and compositions comprising supramolecular constructs
US7807171B2 (en)	2003-07-25	2010-10-05	Ac Immune Sa	Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
AT500483B1 (de) *	2004-07-13	2006-01-15	Mattner Frank Dr	Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung
AT413946B (de) *	2004-07-13	2006-07-15	Mattner Frank Dr	Impfstoff gegen die alzheimer-krankheit
AU2006246382A1 (en) *	2005-05-05	2006-11-16	Merck Sharp & Dohme Corp.	Peptide conjugate compositions and methods for the prevention and treatment of Alzheimer's disease
EP1987361A4 (de) *	2006-01-30	2009-03-04	Invitrogen Corp	Zusammensetzungen und verfahren zur erkennung und quantifizierung toxischer substanzen in krankheitsstadien
WO2009029716A1 (en)	2007-08-28	2009-03-05	Ramot At Tel Aviv University	Peptides inducing a cd4i conformation in hiv gp120 while retaining vacant cd4 binding site
WO2009079566A2 (en) *	2007-12-18	2009-06-25	Acumen Pharmaceuticals, Inc.	Novel addl receptor polypeptides, polynucleotides and host cells for recombinant production
US9241987B2 (en)	2009-11-20	2016-01-26	The University Of Chicago	Methods and compositions related to immunogenic fibrils
EP2603233A1 (de)	2010-08-12	2013-06-19	AC Immune S.A.	Manipulation von impfstoffen
JP6027011B2 (ja)	2010-10-26	2016-11-16	エーシーイミューンソシエテアノニム	疎水性部分によって修飾されたペプチドを含むリポソームベースの構築物
ES2969952T3 (es)	2011-04-22	2024-05-23	Wyeth Llc	Composiciones relacionadas con una toxina mutante de Clostridium difficile y sus procedimientos
BR122016023101B1 (pt)	2012-10-21	2022-03-22	Pfizer Inc	Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
WO2021255690A2 (en)	2020-06-19	2021-12-23	Pfizer Inc.	Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5229490A (en) *	1987-05-06	1993-07-20	The Rockefeller University	Multiple antigen peptide system
CA2172305A1 (en) *	1995-03-30	1996-10-01	Muneo Aoyama	Multiple antigenic peptide comprising at least two hepatitis c virus-associated peptides
EP0861900A1 (de) *	1997-02-21	1998-09-02	Erziehungsdirektion Of The Canton Zurich	Immunologischer Nachweis von Prionen
US6905686B1 (en) *	1997-12-02	2005-06-14	Neuralab Limited	Active immunization for treatment of alzheimer's disease
DE19838751A1 (de) *	1998-08-26	2000-03-09	Hubert Kalbacher	Verfahren zur Herstellung einer Affinitätsmatrix, Zwischenerzeugnis zur Herstellung und Anwendung der Affinitätsmatrix
US6787637B1 (en) *	1999-05-28	2004-09-07	Neuralab Limited	N-Terminal amyloid-β antibodies
AU5522600A (en) *	1999-06-29	2001-01-22	Dako A/S	Detection using dendrimers bearing labels and probes

2002
- 2002-06-20 ES ES02737552T patent/ES2279869T3/es not_active Expired - Lifetime
- 2002-06-20 AT AT02737552T patent/ATE349468T1/de not_active IP Right Cessation
- 2002-06-20 CA CA002450783A patent/CA2450783A1/en not_active Abandoned
- 2002-06-20 WO PCT/US2002/019567 patent/WO2003000719A2/en not_active Ceased
- 2002-06-20 DK DK02737552T patent/DK1397380T3/da active
- 2002-06-20 PT PT02737552T patent/PT1397380E/pt unknown
- 2002-06-20 AU AU2002310474A patent/AU2002310474A1/en not_active Abandoned
- 2002-06-20 DE DE60217107T patent/DE60217107T2/de not_active Expired - Fee Related
- 2002-06-20 EP EP02737552A patent/EP1397380B1/de not_active Expired - Lifetime
- 2002-06-20 US US10/481,642 patent/US20050053575A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20050053575A1 (en)	2005-03-10
DE60217107T2 (de)	2007-08-23
WO2003000719A3 (en)	2003-12-11
PT1397380E (pt)	2007-04-30
ES2279869T3 (es)	2007-09-01
EP1397380B1 (de)	2006-12-27
AU2002310474A1 (en)	2003-01-08
WO2003000719A8 (en)	2004-02-19
WO2003000719A2 (en)	2003-01-03
CA2450783A1 (en)	2003-01-03
ATE349468T1 (de)	2007-01-15
DE60217107D1 (de)	2007-02-08
EP1397380A2 (de)	2004-03-17

Publication	Publication Date	Title
ATE349468T1 (de)	2007-01-15	Mehrantigenisches peptid enthaltend mehrere kopien eines epitopes von einem ablagerungsformenden polypeptid und dessen verwendung
AR075047A1 (es)	2011-03-02	Metodos y composiciones en base a la proteina tipo 2 de la toxina shiga. polipeptido purificado. anticuerpo ant-stx2. kit.
NO20063026L (no)	2006-08-28	Antistoffer
ZA200207992B (en)	2003-07-02	Synthetic immunogenic but non-amyloidogenic peptides homologous to amyloid for induction of an immune response to amyloid and amyloid deposits.
WO2006036550A3 (en)	2006-08-10	Listeria-based and llo-based vaccines
SE0103754L (sv)	2002-10-06	Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
PE20080036A1 (es)	2008-03-06	Anticuerpos humanos para la interleucina-13 (il13)
TR199801722T2 (xx)	1998-12-21	Peptit imm�nojenler.
MX9207113A (es)	1994-05-31	Fragmento de adn, peptido que comprende una proteina superficial ha de un virus de gripe a y vacuna que comprende tal peptido.
CO2022001195A2 (es)	2022-03-08	Anticuerpos dirigidos contra dll3 y usos de los mismos
CO5700790A2 (es)	2006-11-30	Composiciones de vacuna que comprenden una interleucina 18 y sistema de adyuvante de saponina
DE60319350D1 (de)	2008-04-10	Gemeinsame epitope von antigenen aus einer multigen-familie
NO20081043L (no)	2008-04-07	Vaksine for fisk
CO6210756A2 (es)	2010-10-20	La proteina linfopoyetina estromal timica canina y usos de la misma
DOP2020000192A (es)	2021-04-30	Conjugados del péptido de fusión péptido similar al glucagón 1 (glp-1) acoplado al péptido tirosina tirosina y usos de estos
ATE517340T1 (de)	2011-08-15	Sätze gegen kurze epitope gerichteter digitaler antikörper sowie diese verwendende verfahren
DK0880360T3 (da)	2003-01-27	Hidtil ukendte fremgangsmåder til vaccination og vacciner dertil, hvilke vacciner omfatter en nucleinsyre, der koder en første epitop, og et peptid, der indeholder en sekundær epitop
BRPI0508551A (pt)	2007-08-14	seqüências de ácidos nucléicos de lactobacillus acidophilus que codificam proteìnas relacionadas à utilização de carboidrato e usos dessas
MX2022015734A (es)	2023-01-18	Proteinas de exotoxina a modificadas.
MX2022003074A (es)	2022-06-14	Anticuerpos anti-cd371, y usos de los mismos.
MX2025010274A (es)	2025-10-01	Composiciones para su uso en el tratamiento de clamidia
NO20011537L (no)	2001-05-28	Chemokin-reseptorpeptidvaksiner for behandling og forebygging av diabetes
ATE453714T1 (de)	2010-01-15	Antigene aus cryptosporidium parvum, antikörper dagegen und diagnostische und therapeutische zusammensetzungen
DE60132427D1 (de)	2008-03-06	Gebrauch von opri lipoprotein aus pseudomonas als th1 induzierendes natürliches adjuvans für heterologe antigene
NO20025146L (no)	2002-12-05	Isolering og karakterisering av csa-operonet (ETEC-CS4 pili) og fremgangsmåter for anvendelse derav