SE0103754L - Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid - Google Patents

Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid

Info

Publication number
SE0103754L
SE0103754L SE0103754A SE0103754A SE0103754L SE 0103754 L SE0103754 L SE 0103754L SE 0103754 A SE0103754 A SE 0103754A SE 0103754 A SE0103754 A SE 0103754A SE 0103754 L SE0103754 L SE 0103754L
Authority
SE
Sweden
Prior art keywords
peptides
cardiovascular diseases
apolipoprotein
immunization
therapeutic treatment
Prior art date
Application number
SE0103754A
Other languages
English (en)
Other versions
SE0103754D0 (sv
Inventor
Jan Nilsson
Prediman K Shah
Original Assignee
Forskarpatent I Syd Ab
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0101232A external-priority patent/SE0101232D0/sv
Application filed by Forskarpatent I Syd Ab, Cedars Sinai Medical Center filed Critical Forskarpatent I Syd Ab
Priority to SE0103754A priority Critical patent/SE0103754L/sv
Publication of SE0103754D0 publication Critical patent/SE0103754D0/sv
Priority to US10/115,072 priority patent/US20030105003A1/en
Priority to ES10181267.5T priority patent/ES2546293T3/es
Priority to EP02714667A priority patent/EP1383526B1/en
Priority to EP10180845A priority patent/EP2289924A1/en
Priority to EP10180091A priority patent/EP2305706A1/en
Priority to AT08151489T priority patent/ATE510851T1/de
Priority to DK08151489.5T priority patent/DK2006301T3/da
Priority to AT02714667T priority patent/ATE415423T1/de
Priority to EP10181253.5A priority patent/EP2289934B1/en
Priority to EP10180168A priority patent/EP2295461A1/en
Priority to EP10181267.5A priority patent/EP2295464B1/en
Priority to EP10180188A priority patent/EP2289916A1/en
Priority to EP10180172A priority patent/EP2289915A1/en
Priority to DE60230029T priority patent/DE60230029D1/de
Priority to PCT/SE2002/000679 priority patent/WO2002080954A1/en
Priority to EP10180835A priority patent/EP2289922A1/en
Priority to CA2443223A priority patent/CA2443223C/en
Priority to EP10180826A priority patent/EP2289920A1/en
Priority to PL391615A priority patent/PL217858B1/pl
Priority to EP08167533A priority patent/EP2147930A3/en
Priority to EP10180099A priority patent/EP2295458A1/en
Priority to PL385189A priority patent/PL215401B1/pl
Priority to IL15828502A priority patent/IL158285A0/xx
Priority to PL400308A priority patent/PL400308A1/pl
Priority to EP08167531A priority patent/EP2147929A3/en
Priority to EP08158141A priority patent/EP2147928A3/en
Priority to BRPI0216049A priority patent/BRPI0216049B8/pt
Priority to EP10181263A priority patent/EP2295463A1/en
Priority to ES02714667T priority patent/ES2317999T3/es
Priority to EP10180111A priority patent/EP2289914A1/en
Priority to EP10180026A priority patent/EP2295457A1/en
Priority to EP10181273A priority patent/EP2289935A1/en
Priority to CA2827167A priority patent/CA2827167A1/en
Priority to CNA2009100095655A priority patent/CN101486766A/zh
Priority to CN028089405A priority patent/CN1505525B/zh
Priority to EP10181196A priority patent/EP2289928A1/en
Priority to PT02714667T priority patent/PT1383526E/pt
Priority to EP10181203A priority patent/EP2289929A1/en
Priority to JP2002578993A priority patent/JP2004529143A/ja
Priority to EP10181245A priority patent/EP2289933A1/en
Priority to EP10180109A priority patent/EP2289913A1/en
Priority to EP10181217A priority patent/EP2289931A1/en
Priority to EP10180162.9A priority patent/EP2295460B1/en
Priority to RU2003132443/15A priority patent/RU2296582C2/ru
Priority to EP10181188A priority patent/EP2289927A1/en
Priority to BRPI0216033A priority patent/BRPI0216033B8/pt
Priority to EP10180176A priority patent/EP2305708A1/en
Priority to EP10180106A priority patent/EP2289912A1/en
Priority to DK02714667T priority patent/DK1383526T3/da
Priority to EP10181167A priority patent/EP2289925A1/en
Priority to EP10181173A priority patent/EP2289926A1/en
Priority to PL02367301A priority patent/PL367301A1/xx
Priority to EP10181213A priority patent/EP2289930A1/en
Priority to EEP200300487A priority patent/EE200300487A/xx
Priority to EP10180823A priority patent/EP2289919A1/en
Priority to EP10180184A priority patent/EP2295462A1/en
Priority to EP10181227A priority patent/EP2289932A1/en
Priority to EP08167532A priority patent/EP2147680A3/en
Priority to EP08151489A priority patent/EP2006301B1/en
Priority to EP07119130A priority patent/EP1918300A3/en
Priority to BR0208685-9A priority patent/BR0208685A/pt
Priority to AU2002246484A priority patent/AU2002246484B8/en
Priority to CA2606839A priority patent/CA2606839C/en
Priority to CN2007101953989A priority patent/CN101284874B/zh
Priority to CN201210322795.9A priority patent/CN103122031B/zh
Priority to EP10180828A priority patent/EP2289921A1/en
Priority to EP10180199A priority patent/EP2289918A1/en
Priority to EEP200700052A priority patent/EE200700052A/xx
Priority to EP10180156A priority patent/EP2295459A1/en
Priority to DK10181267.5T priority patent/DK2295464T3/en
Priority to EP10180193A priority patent/EP2289917A1/en
Priority to EP10180838A priority patent/EP2289923A1/en
Priority to EP10180115A priority patent/EP2305707A1/en
Publication of SE0103754L publication Critical patent/SE0103754L/sv
Priority to IL158285A priority patent/IL158285A/en
Priority to US11/485,549 priority patent/US7537758B2/en
Priority to US11/924,010 priority patent/US7527795B2/en
Priority to US11/930,625 priority patent/US7528225B2/en
Priority to US11/930,969 priority patent/US20090117137A1/en
Priority to US11/930,859 priority patent/US7544360B2/en
Priority to US11/930,910 priority patent/US7556811B2/en
Priority to IL188286A priority patent/IL188286A0/en
Priority to JP2008015545A priority patent/JP2008169215A/ja
Priority to IL195356A priority patent/IL195356A0/en
Priority to CY20091100202T priority patent/CY1108817T1/el
Priority to US12/394,857 priority patent/US7704499B2/en
Priority to US12/394,827 priority patent/US8025876B2/en
Priority to US12/394,744 priority patent/US20090226475A1/en
Priority to US12/394,886 priority patent/US8029786B2/en
Priority to US12/394,919 priority patent/US8034336B2/en
Priority to US12/394,787 priority patent/US7785589B2/en
Priority to JP2009133383A priority patent/JP5270456B2/ja
Priority to US12/644,810 priority patent/US20100183706A1/en
Priority to JP2010239477A priority patent/JP5300819B2/ja
Priority to JP2010239478A priority patent/JP5300820B2/ja
Priority to US13/177,897 priority patent/USRE43581E1/en
Priority to US13/736,644 priority patent/US8642726B2/en
Priority to US13/736,636 priority patent/US8642043B2/en
Priority to US13/736,645 priority patent/US8470768B2/en
Priority to US13/736,633 priority patent/US8647628B2/en
Priority to JP2013034312A priority patent/JP5613890B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
SE0103754A 2001-04-05 2001-11-09 Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid SE0103754L (sv)

Priority Applications (101)

Application Number Priority Date Filing Date Title
SE0103754A SE0103754L (sv) 2001-04-05 2001-11-09 Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
US10/115,072 US20030105003A1 (en) 2001-04-05 2002-04-04 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
ES10181267.5T ES2546293T3 (es) 2001-04-05 2002-04-05 Terapia de inmunización basada en péptidos para el tratamiento de aterosclerosis que fija ApoB como objetivo
EP02714667A EP1383526B1 (en) 2001-04-05 2002-04-05 Immunization therapy for treatment of atherosclerosis
EP10180845A EP2289924A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180091A EP2305706A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
AT08151489T ATE510851T1 (de) 2001-04-05 2002-04-05 Auf peptiden basierende immunisierungstherapie zur behandlung von atherosklerose
DK08151489.5T DK2006301T3 (da) 2001-04-05 2002-04-05 Peptid-baseret immuniseringsterapi til behandling af atherosklerose
AT02714667T ATE415423T1 (de) 2001-04-05 2002-04-05 Immunisierungstherapie zur behandlung von atherosklerose
EP10181253.5A EP2289934B1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis
EP10180168A EP2295461A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10181267.5A EP2295464B1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis targeting ApoB100
EP10180188A EP2289916A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180172A EP2289915A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
DE60230029T DE60230029D1 (de) 2001-04-05 2002-04-05 Immunisierungstherapie zur behandlung von atherosklerose
PCT/SE2002/000679 WO2002080954A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180835A EP2289922A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
CA2443223A CA2443223C (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180826A EP2289920A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
PL391615A PL217858B1 (pl) 2001-04-05 2002-04-05 Fragment apolipoproteiny B lub jego miejsce aktywne, zawierająca go kompozycja farmaceutyczna i szczepionka, zastosowanie tego fragmentu, szczepionka zawierająca przeciwciało przeciwko temu fragmentowi, sposób diagnozowania in vitro oraz zastosowanie tego przeciwciała
EP08167533A EP2147930A3 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180099A EP2295458A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
PL385189A PL215401B1 (pl) 2001-04-05 2002-04-05 Fragment apolipoproteiny B lub jego miejsce aktywne, zawierajaca go kompozycja farmaceutyczna i szczepionka, zastosowanie tego fragmentu , szczepionka zawierajaca przeciwcialo przeciwko temu fragmentowi, sposób diagnozowania in vitro oraz zastosowanie tego przeciwciala
IL15828502A IL158285A0 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-base assay for determination of immune responses against oxidized low density lipoprotein
PL400308A PL400308A1 (pl) 2001-04-05 2002-04-05 Terapia immunizacyjna w oparciu o peptydy do leczenia miazdzycy oraz w oparciu o peptydy do okreslania odpowiedzi odpornosci przeciwko utlenionym lipoproteinom o niskiej gestosci
EP08167531A EP2147929A3 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP08158141A EP2147928A3 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerososis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
BRPI0216049A BRPI0216049B8 (pt) 2001-04-05 2002-04-05 "terapia de imunização à base de peptídeo para tratamento de arteriosclerose"
EP10181263A EP2295463A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
ES02714667T ES2317999T3 (es) 2001-04-05 2002-04-05 Terapia de inmunizacion para el tratamiento de la ateroesclerosis.
EP10180111A EP2289914A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180026A EP2295457A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10181273A EP2289935A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
CA2827167A CA2827167A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
CNA2009100095655A CN101486766A (zh) 2001-04-05 2002-04-05 以肽为基础的治疗动脉粥样硬化的免疫疗法，和以肽为基础的用于确定针对氧化低密度脂蛋白的免疫反应的检测方法
CN028089405A CN1505525B (zh) 2001-04-05 2002-04-05 以肽为基础的治疗动脉粥样硬化的免疫疗法,和以肽为基础的用于确定针对氧化低密度脂蛋白的免疫反应的检测方法
EP10181196A EP2289928A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
PT02714667T PT1383526E (pt) 2001-04-05 2002-04-05 Terapia de imunização para o tratamento de aterosclerose
EP10181203A EP2289929A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
JP2002578993A JP2004529143A (ja) 2001-04-05 2002-04-05 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
EP10181245A EP2289933A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180109A EP2289913A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10181217A EP2289931A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180162.9A EP2295460B1 (en) 2001-04-05 2002-04-05 Peptide- or antibody-based immunization therapy for treatment of atherosclerosis targeting ApoB100
RU2003132443/15A RU2296582C2 (ru) 2001-04-05 2002-04-05 Фрагменты пептидов, фармацевтические композиции и вакцины на их основе и их применение для профилактики и терапии атеросклероза
EP10181188A EP2289927A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
BRPI0216033A BRPI0216033B8 (pt) 2001-04-05 2002-04-05 "terapia de imunização à base de peptídio para tratamento de arteriosclerose"
EP10180176A EP2305708A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180106A EP2289912A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
DK02714667T DK1383526T3 (da) 2001-04-05 2002-04-05 Immuniseringsterapi til behandling af aterosklerose
EP10181167A EP2289925A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10181173A EP2289926A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
PL02367301A PL367301A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10181213A EP2289930A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EEP200300487A EE200300487A (et) 2001-04-05 2002-04-05 Peptiid-põhine immunoteraapia ateroskleroosi raviks ja peptiid-põhise määramise arendamine immuunvastuste määramiseks oksüdeeritud madala tihedusega lipoproteiini vastu
EP10180823A EP2289919A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180184A EP2295462A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10181227A EP2289932A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP08167532A EP2147680A3 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP08151489A EP2006301B1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis
EP07119130A EP1918300A3 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis
BR0208685-9A BR0208685A (pt) 2001-04-05 2002-04-05 Terapia de imunização à base de peptìdio para tratamento de arteriosclerose e desenvolvimento de ensaio à base de peptìdio para determinação de respostas imunes contra lipoproteìna oxidada de baixa densidade
AU2002246484A AU2002246484B8 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
CA2606839A CA2606839C (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
CN2007101953989A CN101284874B (zh) 2001-04-05 2002-04-05 以肽为基础的治疗动脉粥样硬化的免疫疗法
CN201210322795.9A CN103122031B (zh) 2001-04-05 2002-04-05 以肽为基础的治疗动脉粥样硬化的免疫疗法
EP10180828A EP2289921A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180199A EP2289918A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EEP200700052A EE200700052A (et) 2001-04-05 2002-04-05 Antikeha he v?i mitme apo-lipoproteiin B fragmendi vastu
EP10180156A EP2295459A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
DK10181267.5T DK2295464T3 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for the treatment of atherosclerosis targeting ApoB100
EP10180193A EP2289917A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180838A EP2289923A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
EP10180115A EP2305707A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
IL158285A IL158285A (en) 2001-04-05 2003-10-07 Peptides for preparing medicament for immuno- therapy of atherosclerosis and development of peptide-base assay for determination of immune responses against oxidized low density lipoprotein
US11/485,549 US7537758B2 (en) 2001-04-05 2006-07-12 Antibodies against a peptide epitope of apolipoprotein B
US11/924,010 US7527795B2 (en) 2001-04-05 2007-10-25 Peptide epitopes of apolipoprotein B
US11/930,625 US7528225B2 (en) 2001-04-05 2007-10-31 Peptide epitopes of apolipoprotein B
US11/930,969 US20090117137A1 (en) 2001-04-05 2007-10-31 Peptide epitopes of apolipoprotein b
US11/930,859 US7544360B2 (en) 2001-04-05 2007-10-31 Peptide epitopes of apolipoprotein B
US11/930,910 US7556811B2 (en) 2001-04-05 2007-10-31 Peptide epitopes of apolipoprotein B
IL188286A IL188286A0 (en) 2001-04-05 2007-12-20 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
JP2008015545A JP2008169215A (ja) 2001-04-05 2008-01-25 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
IL195356A IL195356A0 (en) 2001-04-05 2008-11-18 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
CY20091100202T CY1108817T1 (el) 2001-04-05 2009-02-24 Ανοσολογικη θεραπεια για την αντιμετωπιση της αθηροσκληρωσης
US12/394,857 US7704499B2 (en) 2001-04-05 2009-02-27 Antibodies against a peptide epitope of apoliporotein B
US12/394,827 US8025876B2 (en) 2001-04-05 2009-02-27 Antibodies against a peptide epitope of apolipoprotein B
US12/394,744 US20090226475A1 (en) 2001-04-05 2009-02-27 Peptide-based immunization therapy for treatment of atherosclerosis
US12/394,886 US8029786B2 (en) 2001-04-05 2009-02-27 Antibodies against a peptide epitope of apolipoprotein B
US12/394,919 US8034336B2 (en) 2001-04-05 2009-02-27 Antibodies against a peptide epitope of apoliprotein B
US12/394,787 US7785589B2 (en) 2001-04-05 2009-02-27 Antibodies against a peptide epitope of apolipoprotein B
JP2009133383A JP5270456B2 (ja) 2001-04-05 2009-06-02 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
US12/644,810 US20100183706A1 (en) 2001-04-05 2009-12-22 Peptide epitopes of apolipoprotein b
JP2010239477A JP5300819B2 (ja) 2001-04-05 2010-10-26 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
JP2010239478A JP5300820B2 (ja) 2001-04-05 2010-10-26 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発
US13/177,897 USRE43581E1 (en) 2001-04-05 2011-07-07 Peptide epitopes of apolipoprotein B
US13/736,644 US8642726B2 (en) 2001-04-05 2013-01-08 Peptide epitopes of apolipoprotein B
US13/736,636 US8642043B2 (en) 2001-04-05 2013-01-08 Peptide epitopes of apolipoprotein B
US13/736,645 US8470768B2 (en) 2001-04-05 2013-01-08 Peptide epitopes of apolipoprotein B
US13/736,633 US8647628B2 (en) 2001-04-05 2013-01-08 Peptide epitopes of apolipoprotein B
JP2013034312A JP5613890B2 (ja) 2001-04-05 2013-02-25 アテローム性動脈硬化症の治療のためのペプチドに基づいた免疫治療、及び酸化した低密度リポ蛋白質に対する免疫応答の測定のためのペプチドベースのアッセーの開発

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0101232A SE0101232D0 (sv) 2001-04-05 2001-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based elisa for determination of immune responses against oxidized low density liprotein
SE0103754A SE0103754L (sv) 2001-04-05 2001-11-09 Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid

Publications (2)

Publication Number Publication Date
SE0103754D0 SE0103754D0 (sv) 2001-11-09
SE0103754L true SE0103754L (sv) 2002-10-06

Family

ID=26655437

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0103754A SE0103754L (sv) 2001-04-05 2001-11-09 Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid

Country Status (18)

Country Link
EP (42) EP2289915A1 (sv)
JP (6) JP2004529143A (sv)
CN (4) CN101284874B (sv)
AT (2) ATE510851T1 (sv)
AU (1) AU2002246484B8 (sv)
BR (1) BR0208685A (sv)
CA (3) CA2827167A1 (sv)
CY (1) CY1108817T1 (sv)
DE (1) DE60230029D1 (sv)
DK (3) DK2006301T3 (sv)
EE (2) EE200300487A (sv)
ES (2) ES2546293T3 (sv)
IL (4) IL158285A0 (sv)
PL (4) PL367301A1 (sv)
PT (1) PT1383526E (sv)
RU (1) RU2296582C2 (sv)
SE (1) SE0103754L (sv)
WO (1) WO2002080954A1 (sv)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030105003A1 (en) 2001-04-05 2003-06-05 Jan Nilsson Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
SE0103754L (sv) * 2001-04-05 2002-10-06 Forskarpatent I Syd Ab Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
MXPA04002848A (es) 2001-09-28 2005-06-06 Esperion Therapeutics Inc Prevencion y tratamiento de restenosis por administracion local de medicamento.
SE0302312D0 (sv) 2002-10-04 2003-08-27 Forskarpatent I Syd Ab Peptide-based passive immunization therapy for treatment of atherosclerosis
CA2500895A1 (en) * 2002-10-04 2004-04-15 Forskarpatent I Syd Ab Peptide-based passive immunization therapy for treatment of atherosclerosis
SE0302422D0 (sv) 2003-09-11 2003-09-11 Forskarpatent I Syd Ab Peptide-based immunization therapy for treatment of atherosclerosis
SE0400683D0 (sv) * 2004-03-19 2004-03-19 Forskarpatent I Syd Ab Use of modified extracellular matrix proteins in diagnosis and treatment of a atherosclerosis
JP2007531537A (ja) 2004-04-06 2007-11-08 セダーズ−シナイ　メディカル　センター アポリポタンパク質ａ−ｉおよびアポリポタンパク質ａ−ｉｍｉｌａｎｏをコードする組換えアデノ随伴ウイルスベクターによる血管疾患の予防および処置
CN103908669B (zh) 2004-04-15 2017-07-04 阿瑟拉生物技术公司 磷酸胆碱偶联物和相应抗体
EP1676602A1 (en) * 2005-01-04 2006-07-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Continuous administration of epitopes derived from protein present in atherosclerotic plaque for the treatment of atherosclerosis
GB0517878D0 (en) 2005-09-02 2005-10-12 Bioinvent Int Ab Immunotherapeutic treatment
WO2008080030A2 (en) * 2006-12-22 2008-07-03 Abbott Laboratories Cardiovascular autoimmune disease panel and methods of using same
WO2008104194A1 (en) * 2007-02-28 2008-09-04 Bioinvent International Ab Oxidized ldl and antibodies thereto for the treatment of atheroscleroti c plaques
EP2137162B1 (en) 2007-03-15 2018-08-01 Novartis AG Organic compounds and their uses
EP2538222B1 (en) * 2007-11-05 2021-08-25 Nordic Bioscience A/S Biochemical markers for CVD risk assessment
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
JP5742002B2 (ja) * 2008-08-15 2015-07-01 藤倉化成株式会社 動脈硬化診断用ポリペプチドマーカー、及び該マーカー等を用いる動脈硬化の検出を補助する方法、並びに動脈硬化診断用キット
WO2011060329A1 (en) 2009-11-14 2011-05-19 Kuang-Yuh Chyu Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis
US8506964B2 (en) * 2010-02-05 2013-08-13 Cardiovax, Llc Fusion proteins and related compositions, methods and systems for treatment and/or prevention of atherosclerosis
US20130142760A1 (en) 2010-08-18 2013-06-06 Cedars-Sinai Medical Center Atherosclerosis inhibition via modulation of monocyte-macrophage phenotype using apo a-i milano gene transfer
CA2817543A1 (en) * 2010-11-12 2012-06-07 Cedars-Sinai Medical Center Immunomodulatory methods and systems for treatment and/or prevention of hypertension
RU2013126888A (ru) * 2010-11-12 2014-12-20 Седарс-Синаи Медикал Сентер ИММУНОМОДУЛИРУЮЩИЕ КОМПОЗИЦИИ, СПОСОБЫ И СИСТЕМЫ, СОДЕРЖАЩИЕ ИММУНОГЕННЫЕ ФРАГМЕНТЫ АроВ100
RU2013126628A (ru) 2010-11-12 2014-12-20 Седарс-Синаи Медикал Сентер Иммуномодулирующие способы и системы для лечения и/или предотвращения аневризм
MX364425B (es) 2011-08-09 2019-04-25 Athera Biotechnologies Ab Star Nuevos anticuerpos contra fosforilcolina.
EP2741770A4 (en) 2011-08-09 2014-12-31 Athera Biotechnologies Ab ANTIBODY BINDING TO PHOSPHORYLCHOLIN (PC) AND / OR PC CONJUGATES
RU2495048C1 (ru) * 2012-04-18 2013-10-10 Андрей Валентинович Исаев Пептид, обладающий антиатеросклеротическим действием и композиция для профилактики и лечения атеросклероза сосудов
ES2859559T3 (es) 2012-11-06 2021-10-04 Les Hopitaux Univ De Geneve Péptidos miméticos
CN103520713B (zh) * 2013-10-16 2015-10-28 西北农林科技大学 一种ApoB100酵母重组疫苗及其制备方法和应用
CN103860470A (zh) * 2014-03-05 2014-06-18 贵州中泰生物科技有限公司 一种口服高密度脂蛋白脂质体的制备方法
CN105315364B (zh) * 2014-06-17 2018-09-18 广州文瑞生物科技有限公司 胶原蛋白vi疫苗预防动脉粥样硬化
US11130798B2 (en) 2015-05-19 2021-09-28 La Jolla Institute For Allergy And Immunology Human APOB100 epitopes, methods and uses for modulating inflammatory responses, and treating adverse cardiovascular events, disease and atherosclerosis
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
CN108478817B (zh) * 2018-03-16 2020-10-27 北京大学 一种动脉粥样硬化检测试剂及其制备方法
CN112689512B (zh) 2018-05-29 2025-09-05 艾比中心有限责任公司 用于治疗银屑病的组合物和方法
WO2019232081A1 (en) 2018-05-29 2019-12-05 Abcentra, Llc Compositions and methods for treatment of rheumatoid arthritis and accelerated atherosclerosis
CN115025210B (zh) * 2021-03-05 2025-09-05 香港中文大学 减少动脉粥样硬化进展的肽疫苗组合物和药物制剂
CN115025211A (zh) * 2021-11-02 2022-09-09 南京理工大学 用于动脉粥样硬化治疗的纳米疫苗及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970144A (en) 1984-12-31 1990-11-13 International Genetic Engineering Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
US5972890A (en) 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
WO1993018067A1 (en) * 1992-03-06 1993-09-16 Abbott Laboratories Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels
WO1994000592A1 (en) * 1992-06-26 1994-01-06 Exocell, Inc. Monoclonal antibodies against glycated low density lipoprotein
CA2142007C (en) * 1992-08-11 2007-10-30 Robert Glen Urban Immunomodulatory peptides
KR0185334B1 (ko) 1995-11-02 1999-04-01 김은영 인간 혈장 아포지단백질 비-100에 결합하는 생쥐 항체를 암호하는 씨디엔에이
GB9609702D0 (en) * 1996-05-09 1996-07-10 Royal Free Hosp School Med Anticoagulant peptides
GB9620153D0 (en) * 1996-09-27 1996-11-13 Univ Strathclyde Non-naturally occurring lipoprotein particle
GB9705831D0 (en) * 1997-03-20 1997-05-07 Univ Leicester Oxidised ldl
US6635623B1 (en) * 1997-06-13 2003-10-21 Baylor College Of Medicine Lipoproteins as nucleic acid vectors
US6225070B1 (en) 1997-08-07 2001-05-01 The Regents Of The University Of California Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma
US6156315A (en) * 1997-10-10 2000-12-05 The Trustees Of Columbia University In The City Of New York Method for inhibiting the binding of low density lipoprotein to blood vessel matrix
US6309844B1 (en) * 1997-10-15 2001-10-30 Fujirebio Inc. Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same
EP1062512A4 (en) * 1998-03-10 2001-12-12 Univ California METHODS AND TOOLS USED TO IDENTIFY COMPOUNDS THAT MODULATE ATHEROSCLEROSIS BY ALTERATION OF THE LDL-PROTEOGLYCANE BINDING
AU5200699A (en) * 1998-07-13 2000-02-01 University Of Otago Inhibition of lipoprotein formation
IL126447A (en) * 1998-10-04 2004-09-27 Vascular Biogenics Ltd An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis
ATE506615T1 (de) * 1999-10-26 2011-05-15 Univ California Reagenzien und verfahren für diagnose, 'imaging' und behandlung von atherosklerotischen krankheiten
US20020081590A1 (en) * 2000-02-04 2002-06-27 Aeomica, Inc. Methods and apparatus for predicting, confirming, and displaying functional information derived from genomic sequence
WO2001064008A2 (en) * 2000-03-03 2001-09-07 Smithkline Beecham Biologicals S.A. Vaccine for the treatment of artherosclerosis
SE0000855D0 (sv) * 2000-03-15 2000-03-15 Karolinska Innovations Ab Antigenic composition useful as a vaccine against atherosclerosis
GB0017641D0 (en) * 2000-07-18 2000-09-06 Medigene Oy Peptides and their use
EP1186299A1 (en) * 2000-09-12 2002-03-13 Universitair Medisch Centrum Utrecht The diagnosis, prevention, and/or succesful treatment of atherosclerosis, infectious diseases, and disturbances in the immune system
EP1592445A4 (en) * 2000-10-25 2007-01-10 Vincent Agnello METHOD FOR INHIBITING HEPATITIS C VIRUS (HCV) INFECTION AND OTHER FLAVIRIDAE / I FAMILY VIRUSES, AND OTHER BLOODY-VIRUSES COMPLEXING WITH LOW OR VERY LOW DENSITY LIPOPROTEIN DENSITY, BY PREVENTING VIRAL ENTRY IN A CELL
AU2002241603A1 (en) * 2000-11-10 2002-06-03 University Of Utah Research Foundation Carrier system for specific artery wall gene delivery
SE0103754L (sv) * 2001-04-05 2002-10-06 Forskarpatent I Syd Ab Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
CA2446720A1 (en) * 2001-05-15 2002-11-21 Japan Immunoresearch Laboratories Co., Ltd. High density lipoprotein-reactive peptides
CA2454418A1 (en) * 2001-07-20 2003-01-30 Eidgenoessische Technische Hochschule Zurich (Ethz) Compositions and methods for use of bioactive agents derived from sulfated and sulfonated amino acids

Also Published As

Publication number Publication date
EP2305706A1 (en) 2011-04-06
JP2011063598A (ja) 2011-03-31
EP2295461A1 (en) 2011-03-16
EP2147930A3 (en) 2010-04-14
DK1383526T3 (da) 2009-03-30
EP2289934A1 (en) 2011-03-02
EP2289926A1 (en) 2011-03-02
EP2295460A1 (en) 2011-03-16
EP2305708A1 (en) 2011-04-06
EP2289922A1 (en) 2011-03-02
EP2289932A1 (en) 2011-03-02
EP2295458A1 (en) 2011-03-16
AU2002246484B8 (en) 2007-06-14
PL367301A1 (en) 2005-02-21
EP2289917A1 (en) 2011-03-02
EP2295464B1 (en) 2015-06-03
EP2006301A1 (en) 2008-12-24
EP2147680A3 (en) 2010-04-14
RU2296582C2 (ru) 2007-04-10
EP1383526B1 (en) 2008-11-26
DE60230029D1 (de) 2009-01-08
JP5270456B2 (ja) 2013-08-21
CN103122031A (zh) 2013-05-29
EP2289919A1 (en) 2011-03-02
AU2002246484A1 (en) 2002-10-21
EP2289918A1 (en) 2011-03-02
EP2295462A1 (en) 2011-03-16
JP2009191078A (ja) 2009-08-27
IL158285A0 (en) 2004-05-12
CN101284874B (zh) 2012-10-03
PL217858B1 (pl) 2014-08-29
IL158285A (en) 2009-12-24
EP2289927A1 (en) 2011-03-02
CA2606839C (en) 2015-06-09
EP2289933A1 (en) 2011-03-02
CN1505525A (zh) 2004-06-16
EP2289930A1 (en) 2011-03-02
EP2289923A1 (en) 2011-03-02
EP2147929A2 (en) 2010-01-27
CA2606839A1 (en) 2002-10-17
IL188286A0 (en) 2008-03-20
PL400308A1 (pl) 2012-12-17
EP2289925A1 (en) 2011-03-02
ES2546293T3 (es) 2015-09-22
ATE415423T1 (de) 2008-12-15
CA2443223C (en) 2013-11-26
EP2289920A1 (en) 2011-03-02
CN101284874A (zh) 2008-10-15
CN1505525B (zh) 2012-11-07
EP2147680A2 (en) 2010-01-27
DK2295464T3 (en) 2015-08-17
PT1383526E (pt) 2009-02-27
JP2004529143A (ja) 2004-09-24
EP2289915A1 (en) 2011-03-02
EP2289914A1 (en) 2011-03-02
JP2008169215A (ja) 2008-07-24
EP2295457A1 (en) 2011-03-16
SE0103754D0 (sv) 2001-11-09
CN103122031B (zh) 2015-07-22
CY1108817T1 (el) 2014-04-09
CA2827167A1 (en) 2002-10-17
AU2002246484B2 (en) 2007-04-19
BR0208685A (pt) 2004-03-30
DK2006301T3 (da) 2011-09-12
JP5300819B2 (ja) 2013-09-25
EP2147930A2 (en) 2010-01-27
EP1918300A3 (en) 2009-06-17
EP2295459A1 (en) 2011-03-16
EP2295460B1 (en) 2015-06-03
EP1918300A2 (en) 2008-05-07
EP2006301B1 (en) 2011-05-25
EP2305707A1 (en) 2011-04-06
EP2295463A1 (en) 2011-03-16
EP2147928A2 (en) 2010-01-27
ES2317999T3 (es) 2009-05-01
WO2002080954A1 (en) 2002-10-17
IL195356A0 (en) 2009-08-03
EP2289924A1 (en) 2011-03-02
EP2295464A1 (en) 2011-03-16
RU2003132443A (ru) 2005-02-27
EP2289921A1 (en) 2011-03-02
EP2289916A1 (en) 2011-03-02
EP2289934B1 (en) 2013-11-13
EP2289931A1 (en) 2011-03-02
CN101486766A (zh) 2009-07-22
JP2011068654A (ja) 2011-04-07
PL215401B1 (pl) 2013-12-31
JP2013144687A (ja) 2013-07-25
EP2289913A1 (en) 2011-03-02
EE200300487A (et) 2004-02-16
CA2443223A1 (en) 2002-10-17
EP2289912A1 (en) 2011-03-02
EP1383526A1 (en) 2004-01-28
JP5300820B2 (ja) 2013-09-25
EP2289935A1 (en) 2011-03-02
EP2289929A1 (en) 2011-03-02
JP5613890B2 (ja) 2014-10-29
EP2147928A3 (en) 2010-04-14
EP2147929A3 (en) 2010-04-14
ATE510851T1 (de) 2011-06-15
EP2289928A1 (en) 2011-03-02
EE200700052A (et) 2008-08-15

Similar Documents

Publication Publication Date Title
ATE510851T1 (de) Auf peptiden basierende immunisierungstherapie zur behandlung von atherosklerose
CY1117387T1 (el) ΜΟΝΟΚΛΩΝΙΚΑ ΑΝΤΙΣΩΜΑΤΑ Ν-11 ΔΙΑΣΠΑΣΜΕΝΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, ΣΥΝΘΕΣΕΙΣ, ΜΕΘΟΔΟΙ ΚΑΙ ΧΡΗΣΕΙΣ
ATE376559T1 (de) Methoden der verhinderung und behandlung der alzheimer'schen krankheit
NZ551802A (en) A hyperimmune serum-reactive antigen consisting of a polypeptide comprising an amino acid sequence in SEQ ID NO:422 and antigenic fragments thereof
NO20045021L (no) Immunologiske metoder og preparater for behandling av Alzheimers sykdom
PT1691824E (pt) Proteínas pertencentes à família bcl-2 e seus fragmentos e sua utilização em doentes de cancro
DE69703121D1 (de) Verfahren und zusammensetzungen zur verhinderung von entzündungen und angiogenese enthaltend säugetieren cd97 alpha untereinheit
DK1368060T3 (da) HMGB1-proteininhibitorer og/eller antagonister til behandlingen af vaskulære sygdomme
DE69609188D1 (de) Neutralisierende monoklonale antikörper gegen respiratorischen synzytialvirus
ATE419872T1 (de) Vorbeugende und therapeutsche monoklonale antikörper gegen vacciniavirusantigene
TR199801722T2 (xx) Peptit imm�nojenler.
WO2004006952A3 (en) Therapeutic tuberculosis vaccines
AR016295A1 (es) Antigeno de superficies y proteinas utiles de composiciones para el diagnostico y prevencion de la enfermedad de lyme
WO2000073430A3 (de) Vakzine gegen konformationsabhängige antigene sowie gegen antigene, die keine oder nicht ausschliesslich proteine oder peptide sind
CY1114614T1 (el) Αντιγονα αιμοφιλου ινφλουεντσας και αντιστοιχα dna θραυσματα
EE200500012A (et) Peptiid-pähine passiivne immunoteraapia ateroskleroosi raviks
BR0016129A (pt) Molécula de ácido nucléico, vetor recombinante, polipeptìdeo, racemase de aminoácido eucariótica, anticorpos, célula hospedeira, métodos para produzir polipeptìdeo, para detectar um parasita e uma proteìna eucariótica, para triar moléculas ativas, para detectar e quantificar a presença ou a ausência de uma sequência, para inibir uma proteìna eucariótica, para produzir uma racemase de aminoácido recombinante eucariótica e d-aminoácio e para prevenir ou inibir infecção, plasmìdeo, complexo imunológico, kit para detectar um parasita, fragmento de um polinucleotìdeo, proteìna eucariótica, processos para preparar uma proteìna eucariótica purificada, para detectar uma infecção e para infecção e para triar uma molécula, composição imunizadora, composição de vacina, qualquer modificação molecular do gene ou de um fragmento do gene, uso de qualquer modificação molecular ou bioquìmica da atividade enzimática da racemase, e, qualquer molécula ou composto
CY1105380T1 (el) Προτιμωμενα τμηματα της νευρικης νηματικης πρωτεϊνης και μεθοδοι χρησης αυτων
JPH08511508A (ja) ボツリヌス毒素ポリペプチドおよびワクチン増強剤としてのその使用
WO2004030607A3 (en) Peptide-based passive immunization therapy for treatment of atherosclerosis
ATE396203T1 (de) Auf peptiden basierende immunisierungstherapie zur behandlung von atheriosclerose
DK1039931T3 (da) Multivalente rekombinante antistoffer til at behandle HRV infektioner
FR2694938B1 (fr) Nouveaux peptides, anticorps diriges contre ces peptides, anticorps anti-idiotypiques, application a titre de medicaments, compositions pharmaceutiques et kits de diagnostic les renfermant.
EP1390057A4 (en) ANTIBODIES BINDING TO ANTIGENOUS POLYPEPTIDES, NUCLEIC ACIDS COATING ANTIGENS, AND METHODS OF USE
WO2007023189A3 (en) Pharmaceutical composition and its use for the prophylactic or therapeutic treatment of retroviral diseases

Legal Events

Date Code Title Description
NAV Patent application has lapsed