DK13990A - Superaktive humane insulinanaloge - Google Patents

Superaktive humane insulinanaloge Download PDF

Info

Publication number: DK13990A
Authority: DK; Denmark
Prior art keywords: human insulin; insulin analogue; superactive; superactive human; analogue
Prior art date: 1987-07-17

Application number

DK013990A

Other languages

English (en)

Other versions

DK13990D0 (da

Inventor

Panyaotis G Katsoyannis

Gerald P Schwartz

Original Assignee

Sinai School Medicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-17

Filing date

1990-01-17

Publication date

1990-01-17

1990-01-17 Application filed by Sinai School Medicine filed Critical Sinai School Medicine

1990-01-17 Publication of DK13990D0 publication Critical patent/DK13990D0/da

1990-01-17 Publication of DK13990A publication Critical patent/DK13990A/da

Links

PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical class C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Diabetes (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Endocrinology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Obesity (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Emergency Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DK013990A 1987-07-17 1990-01-17 Superaktive humane insulinanaloge DK13990A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/074,558 US4992418A (en)	1987-07-17	1987-07-17	Superactive human insulin analogue-[10-Aspartic Acid-B]Human Insulin
PCT/US1988/002289 WO1989000580A1 (en)	1987-07-17	1988-07-07	Superactive human insulin analogues

Publications (2)

Publication Number	Publication Date
DK13990D0 DK13990D0 (da)	1990-01-17
DK13990A true DK13990A (da)	1990-01-17

Family

ID=22120214

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK013990A DK13990A (da)	1987-07-17	1990-01-17	Superaktive humane insulinanaloge

Country Status (10)

Country	Link
US (1)	US4992418A (da)
EP (1)	EP0382732B1 (da)
JP (1)	JP2729498B2 (da)
KR (1)	KR970009353B1 (da)
AU (1)	AU616131B2 (da)
DE (1)	DE3887338T2 (da)
DK (1)	DK13990A (da)
FI (1)	FI98731C (da)
HU (1)	HU205145B (da)
WO (1)	WO1989000580A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE101620T1 (de) *	1988-06-23	1994-03-15	Hoechst Ag	Mini-proinsulin, seine herstellung und verwendung.
US5656590A (en) *	1991-05-24	1997-08-12	Amylin Pharmaceuticals, Inc.	Treatment of anorexia and related states
IL102240A0 (en) *	1991-06-21	1993-01-14	Lilly Co Eli	Insulin analogs
TW224471B (da) *	1991-11-26	1994-06-01	Lilly Co Eli
US6933272B1 (en)	1998-09-22	2005-08-23	Erik Helmerhorst	Use of non-peptidyl compounds for the treatment of insulin related ailments
EP1458240B1 (en) *	2001-06-08	2008-04-30	Boehringer Ingelheim Pharmaceuticals Inc.	Nucleic acid constructs useful for glucose regulated production of human insulin in somatic cell lines
US7176278B2 (en)	2001-08-30	2007-02-13	Biorexis Technology, Inc.	Modified transferrin fusion proteins
US7396936B1 (en)	2004-11-09	2008-07-08	Kemia, Inc.	Modulators of calcitonin and amylin receptor activity
US7833513B2 (en)	2004-12-03	2010-11-16	Rhode Island Hospital	Treatment of Alzheimer's Disease
EP2074140B8 (en)	2006-10-04	2015-10-28	Case Western Reserve University	Fibrillation-resistant insulin and insulin analogues
US20080260820A1 (en) *	2007-04-19	2008-10-23	Gilles Borrelly	Oral dosage formulations of protease-resistant polypeptides
EP2337563B1 (en)	2008-09-08	2014-04-09	The Board of Trustees of The Leland Stanford Junior University	Modulators of aldehyde dehydrogenase activity and methods of use thereof
KR20110082180A (ko)	2008-10-28	2011-07-18	더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티	알데히드 탈수소효소의 조절자 및 그것의 사용방법
WO2012149106A1 (en)	2011-04-29	2012-11-01	The Board Of Trustees Of The Leland Stanford Junior University	Compositions and methods for increasing proliferation of adult salivary stem cells
JP2014533241A (ja) *	2011-10-27	2014-12-11	ケースウェスタンリザーブユニバーシティＣａｓｅＷｅｓｔｅｒｎｒｅｓｅｒｖｅＵｎｉｖｅｒｓｉｔｙ	超濃縮速効型インスリン類似体製剤
JP6410790B2 (ja)	2013-03-14	2018-10-24	ザボードオブトラスティーズオブザレランドスタンフォードジュニアユニバーシティー	ミトコンドリアアルデヒドデヒドロゲナーゼ−２調節因子およびその使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3420810A (en) *	1966-10-25	1969-01-07	Atomic Energy Commission	Process for joining the a and b chains of insulin
DE2252157C3 (de) *	1972-10-25	1976-03-18	Hoechst Ag	Zwischenprodukte zur herstellung von insulin, insulin-analogen und -derivaten und verfahren zur herstellung von insulin, insulin analogen und derivaten
DE2253327A1 (de) *	1972-10-31	1974-05-09	Hoechst Ag	Verfahren zur herstellung von insulin, insulin-analogen und -derivaten
DD153829A1 (de) *	1979-08-09	1982-02-03	Guenter Losse	Verfahren zur herstellung neuartiger hybridinsuline mit insulinaehnlicher wirkung
US4421685A (en) *	1980-03-27	1983-12-20	Eli Lilly And Company	Process for producing an insulin
US4430266A (en) *	1980-11-28	1984-02-07	Eli Lilly And Company	Process for producing an insulin precursor
DOP1982004086A (es) *	1981-08-27	1988-03-22	Lilly Co Eli	Formula farmaceutica que comprende insulina humana y proinsulina humana
US4652548A (en) *	1981-08-27	1987-03-24	Eli Lilly And Company	Pharmaceutical formulations comprising human insulin, human C-peptide, and human proinsulin
US4459226A (en) *	1982-02-26	1984-07-10	Eli Lilly And Company	Process for recovering insulin
ATE37983T1 (de) *	1982-04-22	1988-11-15	Ici Plc	Mittel mit verzoegerter freigabe.
US4569791A (en) *	1984-06-14	1986-02-11	Eli Lilly And Company	Anti-diabetic compounds
US4581165A (en) *	1984-06-14	1986-04-08	Eli Lilly And Company	Anti-diabetic compounds
US4569792A (en) *	1984-06-14	1986-02-11	Eli Lilly And Company	Anti-diabetic compounds
PH25772A (en) *	1985-08-30	1991-10-18	Novo Industri As	Insulin analogues, process for their preparation

1987
- 1987-07-17 US US07/074,558 patent/US4992418A/en not_active Expired - Fee Related
1988
- 1988-07-07 JP JP63506422A patent/JP2729498B2/ja not_active Expired - Lifetime
- 1988-07-07 EP EP88906597A patent/EP0382732B1/en not_active Expired - Lifetime
- 1988-07-07 DE DE88906597T patent/DE3887338T2/de not_active Expired - Fee Related
- 1988-07-07 HU HU884792A patent/HU205145B/hu not_active IP Right Cessation
- 1988-07-07 WO PCT/US1988/002289 patent/WO1989000580A1/en not_active Ceased
- 1988-07-07 KR KR1019890700480A patent/KR970009353B1/ko not_active Expired - Fee Related
- 1988-07-07 AU AU21269/88A patent/AU616131B2/en not_active Ceased
1990
- 1990-01-16 FI FI900249A patent/FI98731C/fi not_active IP Right Cessation
- 1990-01-17 DK DK013990A patent/DK13990A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUT54178A (en)	1991-01-28
DE3887338T2 (de)	1994-05-05
EP0382732B1 (en)	1994-01-19
FI98731C (fi)	1997-08-11
AU616131B2 (en)	1991-10-17
AU2126988A (en)	1989-02-13
DE3887338D1 (de)	1994-03-03
FI98731B (fi)	1997-04-30
US4992418A (en)	1991-02-12
DK13990D0 (da)	1990-01-17
JP2729498B2 (ja)	1998-03-18
EP0382732A1 (en)	1990-08-22
KR920700227A (ko)	1992-02-19
HU205145B (en)	1992-03-30
KR970009353B1 (ko)	1997-06-10
JPH02504274A (ja)	1990-12-06
FI900249A0 (fi)	1990-01-16
WO1989000580A1 (en)	1989-01-26

Legal Events

Date	Code	Title	Description
2000-03-13	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
FI913037A7 (fi)	1991-06-20	Ihmisen insuliinianalogit
FI896270A7 (fi)	1989-12-22	Lääkeruisku
PT88672A (pt)	1989-07-31	Syringe
DE10075034I1 (de)	2001-05-23	Insulinderivate
DK13990D0 (da)	1990-01-17	Superaktive humane insulinanaloge
BR8806571A (pt)	1989-10-17	Indazois substituidos inseticidas
DK539988D0 (da)	1988-09-28	Ballepresser
DK539888D0 (da)	1988-09-28	Ballepresser
DK13889D0 (da)	1989-01-13	Insecticid
DK54589A (da)	1989-08-09	Humane kolonistmulerende faktorer
DK444288D0 (da)	1988-08-09	Humant reg - protein
DK327488A (da)	1988-12-18	Kanyle
MX14038A (es)	1993-11-01	Composicion insecticida
KR890701560A (ko)	1989-12-20	N-시아노메틸-2-피리디논 살충제
DK540088D0 (da)	1988-09-28	Ballepresser
FI895903A7 (fi)	1989-12-11	Keinosydän
NO891156L (no)	1989-05-10	Superaktive humane insulinanaloger.
ATE100468T1 (de)	1994-02-15	Superaktive menschliche insulin-analoge.
DK539788D0 (da)	1988-09-28	Ballepresser
KR890012334U (ko)	1989-08-07	쥐 덫
KR890006500U (ko)	1989-05-13	드로우어웨이팁
KR890010164U (ko)	1989-07-07	장식용 인조 소나무
NO884613D0 (no)	1988-10-17	Human interleukin-3- og muteiner derav.
DK119391D0 (da)	1991-06-20	Humaninsulinanaloger
DK721588D0 (da)	1988-12-23	Humaninsulinanaloger