DK1399484T3 - Dobbelt-specifik ligand og anvendelse af denne - Google Patents

Dobbelt-specifik ligand og anvendelse af denne

Info

Publication number
DK1399484T3
DK1399484T3 DK02748987.1T DK02748987T DK1399484T3 DK 1399484 T3 DK1399484 T3 DK 1399484T3 DK 02748987 T DK02748987 T DK 02748987T DK 1399484 T3 DK1399484 T3 DK 1399484T3
Authority
DK
Denmark
Prior art keywords
specific ligand
double
variable domain
binding specificity
immunoglobulin
Prior art date
Application number
DK02748987.1T
Other languages
English (en)
Inventor
Greg Mrc Winter
Olga Ignatovich
Ian Tomlinson
Original Assignee
Domantis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42537285&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1399484(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0115841A external-priority patent/GB0115841D0/en
Application filed by Domantis Ltd filed Critical Domantis Ltd
Application granted granted Critical
Publication of DK1399484T3 publication Critical patent/DK1399484T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK02748987.1T 2001-06-28 2002-06-28 Dobbelt-specifik ligand og anvendelse af denne DK1399484T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0115841A GB0115841D0 (en) 2001-06-28 2001-06-28 Ligand
PCT/GB2002/003014 WO2003002609A2 (en) 2001-06-28 2002-06-28 Dual-specific ligand and its use

Publications (1)

Publication Number Publication Date
DK1399484T3 true DK1399484T3 (da) 2010-11-08

Family

ID=42537285

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02748987.1T DK1399484T3 (da) 2001-06-28 2002-06-28 Dobbelt-specifik ligand og anvendelse af denne

Country Status (9)

Country Link
US (1) US20040219643A1 (da)
EP (1) EP1399484B1 (da)
JP (1) JP4303105B2 (da)
AT (1) ATE477280T1 (da)
AU (1) AU2002319402B2 (da)
CA (1) CA2447851C (da)
DE (1) DE60237282D1 (da)
DK (1) DK1399484T3 (da)
WO (1) WO2003002609A2 (da)

Families Citing this family (410)

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EP1399484B1 (en) 2010-08-11
CA2447851A1 (en) 2003-01-09
CA2447851C (en) 2012-08-28
WO2003002609A3 (en) 2003-08-21
JP2005504524A (ja) 2005-02-17
US20040219643A1 (en) 2004-11-04
ATE477280T1 (de) 2010-08-15
JP4303105B2 (ja) 2009-07-29
EP1399484A2 (en) 2004-03-24
WO2003002609A2 (en) 2003-01-09
AU2002319402B2 (en) 2008-09-11

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