DK140393A - Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutisk præparater indeholdende forbindelsen samt fremgangsmåde til fremstilling af forbindelsen - Google Patents

Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutisk præparater indeholdende forbindelsen samt fremgangsmåde til fremstilling af forbindelsen

Info

Publication number
DK140393A
DK140393A DK140393A DK140393A DK140393A DK 140393 A DK140393 A DK 140393A DK 140393 A DK140393 A DK 140393A DK 140393 A DK140393 A DK 140393A DK 140393 A DK140393 A DK 140393A
Authority
DK
Denmark
Prior art keywords
compound
adenovirus infection
nickeloside
iodized
uracil
Prior art date
Application number
DK140393A
Other languages
English (en)
Other versions
DK140393D0 (da
Inventor
John William Talbot Selway
Iii Lowrie Miller Beacham
Susan Mary Daluge
Joel Van Tuttle
Thomas Anthony Krenistky
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK140393A publication Critical patent/DK140393A/da
Publication of DK140393D0 publication Critical patent/DK140393D0/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK931403A 1987-08-22 1993-12-17 Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et laegemiddel mod en adenovirusinfektion, farmaceutisk praeparater indeholdende forbindelsen samt fremgangsmaade til fremstilling af forbindelsen DK140393D0 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878719877A GB8719877D0 (en) 1987-08-22 1987-08-22 Antiviral compounds

Publications (2)

Publication Number Publication Date
DK140393A true DK140393A (da) 1993-12-17
DK140393D0 DK140393D0 (da) 1993-12-17

Family

ID=10622673

Family Applications (3)

Application Number Title Priority Date Filing Date
DK468288A DK169657B1 (da) 1987-08-22 1988-08-19 Anvendelse af visse uracilnucleosider til fremstilling af et lægemiddel mod adenovirusinfektioner samt oftalmiske præparater indeholdende sådanne uracilnucleosider
DK091692A DK169437B1 (da) 1987-08-22 1992-07-14 Chloreret uracilnucleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutiske præparater indeholdende forbindelsen samt fremgangsmåde ti l fremstilling af forbindelsen
DK931403A DK140393D0 (da) 1987-08-22 1993-12-17 Ioderet uracilnicleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et laegemiddel mod en adenovirusinfektion, farmaceutisk praeparater indeholdende forbindelsen samt fremgangsmaade til fremstilling af forbindelsen

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK468288A DK169657B1 (da) 1987-08-22 1988-08-19 Anvendelse af visse uracilnucleosider til fremstilling af et lægemiddel mod adenovirusinfektioner samt oftalmiske præparater indeholdende sådanne uracilnucleosider
DK091692A DK169437B1 (da) 1987-08-22 1992-07-14 Chloreret uracilnucleosid, denne forbindelse til anvendelse mod en adenovirusinfektion, anvendelse af forbindelsen til fremstilling af et lægemiddel mod en adenovirusinfektion, farmaceutiske præparater indeholdende forbindelsen samt fremgangsmåde ti l fremstilling af forbindelsen

Country Status (19)

Country Link
US (2) US5070078A (da)
EP (2) EP0305117B1 (da)
JP (1) JP2634202B2 (da)
KR (1) KR890003382A (da)
AT (1) ATE82681T1 (da)
AU (1) AU613659B2 (da)
CA (1) CA1333361C (da)
DE (1) DE3876174T2 (da)
DK (3) DK169657B1 (da)
ES (1) ES2052732T3 (da)
GB (1) GB8719877D0 (da)
GR (1) GR3006510T3 (da)
HU (1) HU211666A9 (da)
IE (2) IE940696L (da)
MX (1) MX9203416A (da)
NZ (1) NZ225881A (da)
PT (1) PT88306B (da)
SG (1) SG26364G (da)
ZA (1) ZA886182B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719877D0 (en) * 1987-08-22 1987-09-30 Wellcome Found Antiviral compounds
GB8726136D0 (en) * 1987-11-07 1987-12-09 Wellcome Found Therapeutic nucleosides
US5157114A (en) * 1988-08-19 1992-10-20 Burroughs Wellcome Co. 2',3'-dideoxy-3'-fluoro-5-ethyngluridine
WO1990003978A1 (en) * 1988-10-03 1990-04-19 Stichting Rega Vzw 5-halogeno-3'-fluoro-2',3'-dideoxyuridine compounds and their therapeutic application
GB9003543D0 (en) * 1990-02-16 1990-04-11 Wellcome Found Therapeutic nucleosides
US5166327A (en) * 1990-07-31 1992-11-24 Yuki Gosei Kogyo Co., Ltd. Process for producing 3'-deoxy-3-'-fluorothymidine
JP2804184B2 (ja) * 1991-05-14 1998-09-24 シャープ株式会社 ファクシミリ装置
DE4121001C1 (da) * 1991-06-21 1993-05-06 Max-Delbrueck-Centrum Fuer Molekulare Medizin Berlin-Buch, O-1115 Berlin, De
US5341595A (en) * 1992-06-15 1994-08-30 Environmental Growth Chambers Environmental chamber for plant growth analysis
GB9309787D0 (en) * 1993-05-12 1993-06-23 Rhone Poulenc Chemicals Purification of fluoronucleosides
WO1994026762A1 (en) * 1993-05-12 1994-11-24 Rhone-Poulenc Chemicals Limited Preparation of fluoro-nucleosides and intermediates for use therein
SE503787C2 (sv) * 1994-12-07 1996-09-02 Electrolux Ab Anordning för att tillhandahålla kylda eller frysta varor
US5690202A (en) * 1996-04-15 1997-11-25 Myers; John E. Overrunning clutch mechanism
US6514979B1 (en) 1999-03-03 2003-02-04 University Of Maryland Biotechnology Institute Synergistic combinations of guanosine analog reverse transcriptase inhibitors and inosine monophosphate dehydrogenese inhibitors and uses therefor
US6855561B2 (en) * 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
US20030236218A1 (en) * 2002-06-12 2003-12-25 Uckun Fatih M. Aryl phosphate derivatives of d4T with selective activity against adenovirus and HIV
EP1536800B1 (en) * 2002-06-27 2006-01-04 Medivir Ab Synergistic interaction of abacavir and alovudine
CN1248266C (zh) * 2002-12-26 2006-03-29 邱智铭 一种转动式电开关结构
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
RU2628456C1 (ru) * 2016-06-29 2017-08-17 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Новые пиримидиновые ингибиторы репликации аденовируса человека

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE103241C (da) *
GB1251828A (da) * 1968-12-19 1971-11-03
DE1913384C2 (de) * 1968-12-20 1982-12-16 Akademie Der Wissenschaften Der Ddr, Ddr 1199 Berlin 1-(2',3'-Didesoxy-3'-fluor-β-D-xylofuranosyl)-thymin, Verfahren zu seiner Herstellung und dieses enthaltende Cytostatica
GB1189973A (en) * 1969-02-14 1970-04-29 Akad Wissenschaften Ddr Cytostatically-Active 2',3'-Didesoxy-3'-Fluoropyrimidine-Nucleosides
US3775397A (en) * 1969-11-12 1973-11-27 Akad Wissenschaften Ddr Novel cytostatic 2',3'-dideoxy-3'-fluoropyrimidine-nucleosides
DD103241A1 (da) * 1972-12-12 1974-01-12
WO1987000719A1 (fr) * 1985-07-23 1987-01-29 Wolf, Karl Circuit pour l'amorcage et le fonctionnement d'au moins une lampe a decharge de faible ou de haute pression avec oscillations a frequence elevee
EP0217580A3 (en) * 1985-09-17 1990-11-07 The Wellcome Foundation Limited Therapeutic nucleosides
US4710492A (en) * 1986-06-23 1987-12-01 Yale University 3'-azido-2',3'-dideoxy-5-halouridine and its use in treating patients infected with retroviruses
SE8602981D0 (sv) * 1986-07-04 1986-07-04 Astra Laekemedel Ab Novel medicinal use
DD279407A1 (de) * 1986-07-24 1990-06-06 Akad Wissenschaften Ddr Verfahren zur herstellung eines mittels gegen aids
US4880782A (en) * 1986-11-21 1989-11-14 Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. Method of treating viral infections in humans and compositions therefor
FI892451L (fi) * 1986-11-21 1989-05-19 Max Planck Gesellschaft Foerfarande med vilket virusinfektioner i maenniskor kan skoetas och kompositioner anvaenda daeri.
GB8719877D0 (en) * 1987-08-22 1987-09-30 Wellcome Found Antiviral compounds
WO1990003978A1 (en) * 1988-10-03 1990-04-19 Stichting Rega Vzw 5-halogeno-3'-fluoro-2',3'-dideoxyuridine compounds and their therapeutic application

Also Published As

Publication number Publication date
ZA886182B (en) 1990-04-25
DK169437B1 (da) 1994-10-31
PT88306B (pt) 1995-12-29
DK468288A (da) 1989-02-23
EP0305117A3 (en) 1989-12-27
PT88306A (pt) 1989-06-30
IE940696L (en) 1989-02-22
DE3876174D1 (de) 1993-01-07
MX9203416A (es) 1992-07-01
IE882533L (en) 1989-02-22
EP0305117A2 (en) 1989-03-01
IE63655B1 (en) 1995-05-31
CA1333361C (en) 1994-12-06
ATE82681T1 (de) 1992-12-15
EP0305117B1 (en) 1992-11-25
US5070078A (en) 1991-12-03
DK91692A (da) 1992-07-14
GR3006510T3 (da) 1993-06-30
EP0479336A1 (en) 1992-04-08
AU2142988A (en) 1989-05-25
DK468288D0 (da) 1988-08-19
ES2052732T3 (es) 1994-07-16
AU613659B2 (en) 1991-08-08
JPS6468325A (en) 1989-03-14
DK169657B1 (da) 1995-01-09
DK140393D0 (da) 1993-12-17
DE3876174T2 (de) 1993-04-01
JP2634202B2 (ja) 1997-07-23
SG26364G (en) 1995-09-18
HU211666A9 (en) 1995-12-28
KR890003382A (ko) 1989-04-14
NZ225881A (en) 1991-03-26
DK91692D0 (da) 1992-07-14
US5376644A (en) 1994-12-27
GB8719877D0 (en) 1987-09-30

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