DK1404809T3 - Forbedrede hudsubstitutter og anvendelser deraf - Google Patents

Forbedrede hudsubstitutter og anvendelser deraf

Info

Publication number
DK1404809T3
DK1404809T3 DK02725028.1T DK02725028T DK1404809T3 DK 1404809 T3 DK1404809 T3 DK 1404809T3 DK 02725028 T DK02725028 T DK 02725028T DK 1404809 T3 DK1404809 T3 DK 1404809T3
Authority
DK
Denmark
Prior art keywords
improved skin
skin substitutes
substitutes
improved
skin
Prior art date
Application number
DK02725028.1T
Other languages
English (en)
Inventor
Cathy Ann-Rasmussen Ivarie
Paul Barth Conrad
Allen Comer
Lynn Allen-Hoffmann
Michael Hoffmann
Original Assignee
Stratatech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stratatech Corp filed Critical Stratatech Corp
Application granted granted Critical
Publication of DK1404809T3 publication Critical patent/DK1404809T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/04—Screening or testing on artificial tissues
    • C12N2503/06—Screening or testing on artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2510/00—Genetically modified cells
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/142—Toxicological screening, e.g. expression profiles which identify toxicity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/148—Screening for cosmetic compounds
    • C—CHEMISTRY; METALLURGY
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK02725028.1T 2001-03-02 2002-03-01 Forbedrede hudsubstitutter og anvendelser deraf DK1404809T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27303401P 2001-03-02 2001-03-02
US28789801P 2001-05-01 2001-05-01
PCT/US2002/006088 WO2002070729A2 (en) 2001-03-02 2002-03-01 Improved skin substitutes and uses thereof

Publications (1)

Publication Number Publication Date
DK1404809T3 true DK1404809T3 (da) 2014-03-17

Family

ID=26955894

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02725028.1T DK1404809T3 (da) 2001-03-02 2002-03-01 Forbedrede hudsubstitutter og anvendelser deraf

Country Status (11)

Country Link
US (3) US6846675B2 (da)
EP (1) EP1404809B1 (da)
JP (2) JP4317366B2 (da)
AU (3) AU2002255618B2 (da)
CA (1) CA2439899C (da)
DK (1) DK1404809T3 (da)
ES (1) ES2457092T3 (da)
IL (3) IL157667A0 (da)
NZ (4) NZ549526A (da)
PT (1) PT1404809E (da)
WO (1) WO2002070729A2 (da)

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CN107106459B (zh) * 2014-11-17 2021-06-22 韩国比奥科斯全球公司 包含细胞培养基、表皮生长因子和牛血清白蛋白的用于改善皮肤状态的药物组合物
US10894151B2 (en) * 2015-04-23 2021-01-19 Carnegie Mellon University Biosensor tattoos and uses therefor for biomarker monitoring
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JP6817610B2 (ja) * 2016-04-05 2021-01-20 日本メナード化粧品株式会社 三次元培養表皮モデル及びその製造方法、ならびに三次元培養表皮モデルの使用方法
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CN109415692A (zh) * 2016-06-24 2019-03-01 株式会社资生堂 三维培养皮肤片、用于其制造的细胞培养容器和该三维培养皮肤片的制造方法
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JP7437056B2 (ja) * 2020-01-22 2024-02-22 国立研究開発法人産業技術総合研究所 表層に角質層が形成された不死化皮膚細胞の３次元培養物、前記３次元培養物の製造方法、および前記３次元培養物を用いた被検物質の評価方法
JP2023525231A (ja) * 2020-05-13 2023-06-15 ストラタテック コーポレーション 生存能力のある生物工学によって作られた皮膚構築物
JP7041977B2 (ja) * 2020-11-17 2022-03-25 日本メナード化粧品株式会社 三次元培養表皮モデル及びその製造方法、ならびに三次元培養表皮モデルの使用方法
KR102583179B1 (ko) * 2020-11-27 2023-09-26 (주)엑셀세라퓨틱스 칼슘, 상피세포성장인자 및 알부민을 포함하는 각질형성세포 수립 또는 배양용 배지 조성물
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Publication number Publication date
PT1404809E (pt) 2014-03-20
IL195076A0 (en) 2011-08-01
US20020187498A1 (en) 2002-12-12
IL157667A0 (en) 2004-03-28
JP2005505312A (ja) 2005-02-24
IL195076A (en) 2012-02-29
EP1404809A4 (en) 2005-08-10
NZ549527A (en) 2008-04-30
EP1404809A2 (en) 2004-04-07
JP4989674B2 (ja) 2012-08-01
JP2009195232A (ja) 2009-09-03
US7501238B2 (en) 2009-03-10
US6846675B2 (en) 2005-01-25
NZ549528A (en) 2008-04-30
US20020164793A1 (en) 2002-11-07
NZ528166A (en) 2007-05-31
NZ549526A (en) 2009-06-26
WO2002070729A2 (en) 2002-09-12
IL157667A (en) 2009-09-22
AU2006249240A1 (en) 2007-01-04
EP1404809B1 (en) 2013-12-11
CA2439899A1 (en) 2002-09-12
ES2457092T3 (es) 2014-04-24
CA2439899C (en) 2015-09-29
US7541188B2 (en) 2009-06-02
AU2010214639A1 (en) 2010-09-16
AU2006249240B2 (en) 2010-05-27
JP4317366B2 (ja) 2009-08-19
US20050226853A1 (en) 2005-10-13
WO2002070729A3 (en) 2004-01-22
AU2002255618B2 (en) 2006-09-07
AU2010214639B2 (en) 2012-04-19

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