DK1406865T3 - Ravsyrederivater - Google Patents

Ravsyrederivater

Info

Publication number
DK1406865T3
DK1406865T3 DK02738174T DK02738174T DK1406865T3 DK 1406865 T3 DK1406865 T3 DK 1406865T3 DK 02738174 T DK02738174 T DK 02738174T DK 02738174 T DK02738174 T DK 02738174T DK 1406865 T3 DK1406865 T3 DK 1406865T3
Authority
DK
Denmark
Prior art keywords
succinic acid
acid derivatives
pharmaceutical compositions
compounds
processes
Prior art date
Application number
DK02738174T
Other languages
English (en)
Inventor
Thomas Roelle
Markus Albers
Gerhard Hessler
Karl Ziegelbauer
Kevin Bacon
Hiromi Okigami
Ruediger Fischer
Thomas Lehmann
Gerhard Mueller
Masaomi Tajimi
Haruki Hasegawa
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Application granted granted Critical
Publication of DK1406865T3 publication Critical patent/DK1406865T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/55Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK02738174T 2001-07-06 2002-06-24 Ravsyrederivater DK1406865T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0116577A GB2377933A (en) 2001-07-06 2001-07-06 Succinic acid derivatives useful as integrin antagonists

Publications (1)

Publication Number Publication Date
DK1406865T3 true DK1406865T3 (da) 2006-05-08

Family

ID=9918063

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02738174T DK1406865T3 (da) 2001-07-06 2002-06-24 Ravsyrederivater

Country Status (9)

Country Link
US (1) US7064229B2 (da)
EP (1) EP1406865B1 (da)
AT (1) ATE317380T1 (da)
DE (1) DE60209122T2 (da)
DK (1) DK1406865T3 (da)
ES (1) ES2258636T3 (da)
GB (1) GB2377933A (da)
PT (1) PT1406865E (da)
WO (1) WO2003004460A2 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4212358B2 (ja) 2000-12-28 2009-01-21 第一三共株式会社 Vla−4阻害薬
EP1539744A4 (en) 2002-07-11 2007-06-06 Vicuron Pharm Inc N-HYDROXYAMIDE DERIVATIVES WITH ANTIBACTERIAL EFFECT
CA2528586A1 (en) 2003-07-24 2005-02-03 Daiichi Pharmaceutical Co., Ltd. Cyclohexanecarboxylic acid compound
WO2010141932A1 (en) 2009-06-05 2010-12-09 Link Medicine Corporation Aminopyrrolidinone derivatives and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT205017B (de) 1956-12-20 1959-08-25 Lannacher Heilmittel Verfahern zur Herstellung neuer, substituierter Halbamide der Bernsteinsäure
US4482572A (en) 1983-05-05 1984-11-13 Smithkline Beckman Corporation 1-Acylamino-1-cyclopentanecarboxylic acids
DE3535247A1 (de) * 1985-10-03 1987-04-09 Agfa Gevaert Ag Farbfotografisches aufzeichnungsmaterial mit leicht dispergierbaren farbkupplern
US6306840B1 (en) 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
NZ333904A (en) * 1996-07-25 2000-06-23 Biogen Inc VLA-4 and IIb/IIIa cell adhesion inhibitors
WO1999020272A1 (en) 1997-10-21 1999-04-29 Merck & Co., Inc. Azapeptide acids as cell adhesion inhibitors
AU1411499A (en) 1997-11-20 1999-06-15 Merck & Co., Inc. Para-aminomethylaryl carboxamide derivatives
IL136584A (en) 1997-12-23 2005-03-20 Aventis Pharma Ltd SUBSTITUTED beta-ALANINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USES THEREOF
KR20010034317A (ko) 1998-01-23 2001-04-25 한스 루돌프 하우스 Vla-4 길항제
SK20052000A3 (sk) 1998-06-30 2002-08-06 Pfizer Products Inc. Nepeptidové inhibítory VLA-4 dependentnej bunkovej väzby použiteľné pri liečení zápalových, autoimunitných a respiračných chorôb
DE19962936A1 (de) 1999-12-24 2001-06-28 Bayer Ag Neue beta-Aminosäureverbindungen als Integrinantagonisten
DE10006453A1 (de) 2000-02-14 2001-08-16 Bayer Ag Piperidylcarbonsäuren als Integrinantagonisten
DE10019755A1 (de) 2000-04-20 2001-11-08 Bayer Ag Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten
GB2367816A (en) * 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
GB2367817A (en) 2000-10-09 2002-04-17 Bayer Ag Cyclic carboxylic acids as integrin antagonists
GB2369357A (en) 2000-10-09 2002-05-29 Bayer Ag Aliphatic, cyclic amino carboxylic acids as integrin antagonists

Also Published As

Publication number Publication date
PT1406865E (pt) 2006-06-30
DE60209122D1 (de) 2006-04-20
WO2003004460A3 (en) 2003-12-11
GB2377933A (en) 2003-01-29
ATE317380T1 (de) 2006-02-15
DE60209122T2 (de) 2006-08-03
EP1406865B1 (en) 2006-02-08
US7064229B2 (en) 2006-06-20
GB0116577D0 (en) 2001-08-29
WO2003004460A2 (en) 2003-01-16
EP1406865A2 (en) 2004-04-14
US20040254157A1 (en) 2004-12-16
ES2258636T3 (es) 2006-09-01

Similar Documents

Publication Publication Date Title
MXPA04004301A (es) Bencimidazoles sustituidos utiles como inhibidores de la proteina cinasa.
MXPA03011484A (es) Heteroarilos multiciclicos sustituidos con quinuclidinas para el tratamiento de enfermedades.
SE0303180D0 (sv) Novel compounds
SE0302232D0 (sv) Novel Compounds
SE0201635D0 (sv) Novel compounds
NO20074592L (no) Acetylenyl-pyrazolo-pyrimidinderivater som mGluR2-antagonister
ATE307810T1 (de) Imidazol-2-carbonsäureamid derivate als raf- kinase-inhibitoren
HRP20070076A2 (en) Pyrimidine derivatives
BRPI0409109A (pt) novos compostos
SE0301373D0 (sv) Novel compounds
NO20070224L (no) 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
MY139690A (en) Sulfonamide derivatives for the treatment of diseases.
CY1109055T1 (el) 11-((4r,6r)-4,5,6-τριϋδροξυ-3-(r)-υδροξυ-εξυλοκαρβαμοϋλο)-ενδεκαϊνικο οξυ
ATE440834T1 (de) Substituierte arylaminderivate und verwendungsverfahren
CY1107747T1 (el) Υποκατεστημενα τετρακυκλικα παραγωγα πυρρολοκινολονης χρησιμα ως αναστολεις της φωσφοδιεστερασης
CY1111327T1 (el) Υποκατεστημενα παραγωγα κυκλοεξυλοξεικου οξεος
UY28343A1 (es) Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades
MY143390A (en) Sulfonamide derivatives for the treatment of diseases.
EA200801608A1 (ru) Производные бензимидазолонкарбоновой кислоты
TW200505865A (en) Compounds useful for the treatment of diseases
EA200600605A1 (ru) Перегруппированные пентанолы, способ их получения и их применение в качестве противовоспалительных средств
MX2022013890A (es) Sintesis y derivados de acido boronico, formas polimorficas y usos terapeuticos de los mismos.
EA200601462A1 (ru) Соединения для лечения заболеваний
SE0303480D0 (sv) Benzofuranes
ATE438617T1 (de) Substituierte cyclohexyl-1,4-diamin-derivate