DK1409692T3 - Nye peptider afledt af G-proteinet fra RSV, og anvendelse heraf i en vaccine - Google Patents

Nye peptider afledt af G-proteinet fra RSV, og anvendelse heraf i en vaccine

Info

Publication number: DK1409692T3
Authority: DK; Denmark
Prior art keywords: rsv; vaccine; protein; peptides derived; novel peptides
Prior art date: 2001-07-20

Application number

DK02770043T

Other languages

English (en)

Inventor

Nathalie Corvaia

Alain Beck

Gilquin Helene Plotnicky

Ngoc Thien Nguyen

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-20

Filing date

2002-07-19

Publication date

2009-02-02

2002-07-19 Application filed by Pf Medicament filed Critical Pf Medicament

2009-02-02 Application granted granted Critical

2009-02-02 Publication of DK1409692T3 publication Critical patent/DK1409692T3/da

Links

108091006027 G proteins Proteins 0.000 title 1
102000030782 GTP binding Human genes 0.000 title 1
108091000058 GTP-Binding Proteins 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
229960005486 vaccine Drugs 0.000 title 1
241000725643 Respiratory syncytial virus Species 0.000 abstract 2
241000700605 Viruses Species 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
230000009851 immunogenic response Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Pulmonology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK02770043T 2001-07-20 2002-07-19 Nye peptider afledt af G-proteinet fra RSV, og anvendelse heraf i en vaccine DK1409692T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0109731A FR2827605B1 (fr)	2001-07-20	2001-07-20	Nouveaux peptides derives de la proteine g du vrs et leur utilisation dans un vaccin
PCT/FR2002/002599 WO2003010317A1 (fr)	2001-07-20	2002-07-19	Nouveaux peptides derives de la proteine g du vrs et leur utilisation dans un vaccin

Publications (1)

Publication Number	Publication Date
DK1409692T3 true DK1409692T3 (da)	2009-02-02

Family

ID=8865750

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02770043T DK1409692T3 (da)	2001-07-20	2002-07-19	Nye peptider afledt af G-proteinet fra RSV, og anvendelse heraf i en vaccine

Country Status (16)

Country	Link
US (3)	US7309494B2 (da)
EP (1)	EP1409692B1 (da)
JP (1)	JP4310184B2 (da)
CN (1)	CN1556857A (da)
AT (1)	ATE408696T1 (da)
AU (1)	AU2002336148B8 (da)
BR (1)	BR0211296A (da)
CA (1)	CA2455360A1 (da)
DE (1)	DE60228971D1 (da)
DK (1)	DK1409692T3 (da)
ES (1)	ES2314102T3 (da)
FR (1)	FR2827605B1 (da)
MX (1)	MXPA04000597A (da)
PT (1)	PT1409692E (da)
WO (1)	WO2003010317A1 (da)
ZA (1)	ZA200400916B (da)

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ES2316487T5 (es)	2000-10-18	2019-05-13	The Government Of The Us Secretary Department Of Health And Human Services	Composiciones y métodos para modular la inmunidad e infección de RSV
EP1768993A4 (en) *	2004-06-16	2008-07-23	Univ Johns Hopkins	CYSTIC REGION OF HUMAN RESPIRATORY SYNZYTIAL VIRUS AND METHOD OF USE THEREOF
EP1972348A1 (en) *	2007-03-14	2008-09-24	Pierre Fabre Medicament	Novel vaccine composition for the treatment of respiratory infectious diseases
NZ591768A (en)	2008-09-18	2012-11-30	Novartis Ag	Vaccine adjuvant combinations
CA2770304C (en) *	2009-08-04	2019-11-26	The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention	Anti-rsv immunogens and methods of immunization
US8858958B2 (en)	2009-08-27	2014-10-14	Novartis Ag	Adjuvant comprising aluminum, oligonucleotide and polycation
AU2010290896B2 (en)	2009-09-02	2014-07-03	Glaxosmithkline Biologicals S.A.	Immunogenic compositions including TLR activity modulators
US9028834B2 (en)	2009-12-21	2015-05-12	Cornell University	Pneumovirus compositions and methods for using the same
MX343914B (es)	2010-09-01	2016-11-18	Glaxosmithkline Biologicals Sa	Adsorcion de inmunopotenciadores en sales metalicas insolubles.
EP2652511B8 (en)	2010-12-14	2017-06-28	GlaxoSmithKline Biologicals SA	Flow cytometry analysis of materials adsorbed to metal salts
US20140112950A1 (en)	2011-03-02	2014-04-24	Manmohan Singh	Combination vaccines with lower doses of antigen and/or adjuvant
MX356426B (es)	2011-04-04	2018-05-29	Univ Iowa Res Found	Metodos para mejorar inmunogenicidad de vacuna.
ES2395677B1 (es) *	2011-07-29	2013-12-26	Instituto De Salud Carlos Iii	Proteína F del VRSH en conformación pre-fusión estabilizada y anticuerpos neutralizantes específicos frente a la misma.
CN103239734B (zh) *	2012-02-10	2016-02-24	北京艾棣维欣生物技术有限公司	用于预防和/或治疗呼吸道合胞病毒感染的疫苗
DK2822947T3 (da)	2012-03-07	2016-09-19	Glaxosmithkline Biologicals Sa	Argininsalte af en tlr-7-agonist
CN104519910B (zh)	2012-03-07	2017-05-03	诺华股份有限公司	肺炎链球菌抗原的含佐剂制剂
JP6345603B2 (ja)	2012-03-08	2018-06-20	ノバルティスアーゲー	追加免疫ワクチンのアジュバント化された処方物
EA201891945A3 (ru)	2012-08-01	2019-05-31	Бавариан Нордик А/С	Вакцина рекомбинантного модифицированного вируса осповакцины анкара (mva) респираторно-синцитиального вируса (rsv)
CN105085684B (zh) *	2014-05-14	2020-04-17	上海亨臻实业有限公司	Pcsk9靶向重组疫苗设计及其应用
US10744193B2 (en) *	2015-03-30	2020-08-18	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Immunogenic RSV polypeptides
EP3416975A4 (en) *	2016-02-16	2019-08-21	The University of Queensland	NOVEL ALPHA CONOTOXIN PEPTIDES
CN109232737A (zh) *	2016-03-01	2019-01-18	苏州博泰神州生物技术有限公司	一种针对rsv粘附g蛋白表面抗原的全人源单克隆抗体
US20220411783A1 (en) *	2018-10-12	2022-12-29	The Broad Institute, Inc.	Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues
AU2020227545B2 (en)	2019-02-28	2023-10-19	Km Biologics Co., Ltd.	RSV F/G chimeric vaccine
US11360877B2 (en) *	2020-09-14	2022-06-14	International Business Machines Corporation	Forming microservices from monolithic applications
JP2025172274A (ja) *	2022-10-20	2025-11-26	一般財団法人阪大微生物病研究会	Ｒｓウイルスワクチンとしての利用に好適な組成物

Family Cites Families (7)

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WO1987004185A1 (en)	1986-01-14	1987-07-16	University Of North Carolina	Vaccines for human respiratory virus
US5223254A (en)	1987-09-29	1993-06-29	Praxis Biologics, Inc.	Respiratory syncytial virus: vaccines
FR2718452B1 (fr) *	1994-04-06	1996-06-28	Pf Medicament	Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
AUPO026596A0 (en)	1996-06-05	1996-06-27	Biomolecular Research Institute Limited	Viral peptide
FR2766192B1 (fr)	1997-07-17	2001-07-13	Pf Medicament	Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie
FR2776521B1 (fr)	1998-03-27	2000-12-15	Pf Medicament	Utilisation de conjugues p40 actifs par voie nasale
FR2798857B1 (fr) *	1999-09-23	2003-06-06	Pf Medicament	Utilisation d'une proteine de membrane ompa d'enterobacterie associee a un peptide immunogene du vrs pour la preparation de vaccins administrables par voie nasale

2001
- 2001-07-20 FR FR0109731A patent/FR2827605B1/fr not_active Expired - Fee Related
2002
- 2002-07-19 ES ES02770043T patent/ES2314102T3/es not_active Expired - Lifetime
- 2002-07-19 CA CA002455360A patent/CA2455360A1/fr not_active Abandoned
- 2002-07-19 CN CNA028184475A patent/CN1556857A/zh active Pending
- 2002-07-19 WO PCT/FR2002/002599 patent/WO2003010317A1/fr not_active Ceased
- 2002-07-19 PT PT02770043T patent/PT1409692E/pt unknown
- 2002-07-19 DE DE60228971T patent/DE60228971D1/de not_active Expired - Fee Related
- 2002-07-19 MX MXPA04000597A patent/MXPA04000597A/es active IP Right Grant
- 2002-07-19 AU AU2002336148A patent/AU2002336148B8/en not_active Ceased
- 2002-07-19 AT AT02770043T patent/ATE408696T1/de not_active IP Right Cessation
- 2002-07-19 JP JP2003515667A patent/JP4310184B2/ja not_active Expired - Fee Related
- 2002-07-19 US US10/484,298 patent/US7309494B2/en not_active Expired - Fee Related
- 2002-07-19 DK DK02770043T patent/DK1409692T3/da active
- 2002-07-19 BR BR0211296-5A patent/BR0211296A/pt not_active IP Right Cessation
- 2002-07-19 EP EP02770043A patent/EP1409692B1/fr not_active Expired - Lifetime
2004
- 2004-02-04 ZA ZA200400916A patent/ZA200400916B/en unknown
2007
- 2007-11-16 US US11/985,839 patent/US7524627B2/en not_active Expired - Fee Related
2009
- 2009-03-02 US US12/380,671 patent/US20090181042A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE60228971D1 (de)	2008-10-30
ES2314102T3 (es)	2009-03-16
US20090181042A1 (en)	2009-07-16
JP2005511010A (ja)	2005-04-28
BR0211296A (pt)	2004-09-14
FR2827605A1 (fr)	2003-01-24
EP1409692B1 (fr)	2008-09-17
US20040175395A1 (en)	2004-09-09
ZA200400916B (en)	2004-08-25
PT1409692E (pt)	2008-12-26
US7524627B2 (en)	2009-04-28
US7309494B2 (en)	2007-12-18
AU2002336148B8 (en)	2008-06-19
JP4310184B2 (ja)	2009-08-05
US20090036367A1 (en)	2009-02-05
MXPA04000597A (es)	2004-04-20
CA2455360A1 (fr)	2003-02-06
WO2003010317A1 (fr)	2003-02-06
FR2827605B1 (fr)	2004-07-16
EP1409692A1 (fr)	2004-04-21
CN1556857A (zh)	2004-12-22
ATE408696T1 (de)	2008-10-15
AU2002336148B2 (en)	2007-12-13

Publication	Publication Date	Title
PT1409692E (pt)	2008-12-26	Novos péptidos do derivados da proteína g do vírus respiratório sincicial (vrs) e sua utilização numa vacina
CY1123152T1 (el)	2021-10-29	Τροποποιημενες πρωτεϊνες rsv f και μεθοδοι χρησης τους
CY1107146T1 (el)	2012-05-23	Μεθοδοι για προληψη και θεραπεια ασθενειας alzheimer (ad)
ATE451119T1 (de)	2009-12-15	Untereinheit-impfstoff gegen das respiratorische synzytialvirus
EA201070794A1 (ru)	2011-02-28	Рекомбинантные антигены rsv
ATE426412T1 (de)	2009-04-15	Adjuvante influenza-vakzine
ATE542829T1 (de)	2012-02-15	Impfstoff
MXPA05009580A (es)	2005-10-19	Vacuna contra el virus de la influenza.
NO20050008L (no)	2005-04-28	Neisserial vaksinesammensetninger omfattende en kombinasjon av antigener
ATE476983T1 (de)	2010-08-15	Immunostimulierende polynukleotide sequenzen zur verwendung bei der verhinderung und behandlung von viralen erkrankungen der atemwege
MX2014012234A (es)	2014-12-05	Antigenos de consenso del virus sincitial respiratorio humano, constructos de acido nucleico y vacunas hechas de estos, y metodos para utilizarlas.
GB2386072A (en)	2003-09-10	Novel vaccine
DK1881845T3 (da)	2010-06-07	Nipah-virusvacciner
ATE551069T1 (de)	2012-04-15	Mucin-fusionspolypeptid-vakzine, zusammensetzungen und ihre verwendung
DK1471936T3 (da)	2010-04-26	HIV-Vaccine og fremgangsmåde til anvendelse
EA200700496A1 (ru)	2007-10-26	Инактивированная полиомиелитная вакцина, полученная из штамма сейбина вируса полиомиелита
ATE507286T1 (de)	2011-05-15	Immunisierung von fischen gegen virusinfektion
WO2002058725A3 (fr)	2003-01-09	Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin
ATE372129T1 (de)	2007-09-15	Impfstoff von umhüllten viren und verfahren zu seiner herstellung
AR065765A1 (es)	2009-07-01	Composicion de vacuna para el tratamiento de enfermedades infecciosas respiratorias
EP1667634A4 (en)	2008-03-05	VACCINE AGAINST ANTHRAX
MX2007002659A (es)	2007-05-16	Composicion vacunal contra el virus de la hepatitis c.
WO2004092207A3 (en)	2005-04-07	Respiratory syncytial virus (rsv) peptides
ATE424844T1 (de)	2009-03-15	Kombinationsvakzine für geflügel
CY1114309T1 (el)	2016-08-31	Εμβολιο ροταϊου