DK1417488T3 - Cellemigrasionsassay - Google Patents
CellemigrasionsassayInfo
- Publication number
- DK1417488T3 DK1417488T3 DK02739361T DK02739361T DK1417488T3 DK 1417488 T3 DK1417488 T3 DK 1417488T3 DK 02739361 T DK02739361 T DK 02739361T DK 02739361 T DK02739361 T DK 02739361T DK 1417488 T3 DK1417488 T3 DK 1417488T3
- Authority
- DK
- Denmark
- Prior art keywords
- cell migration
- migration assay
- discrimination
- kit
- directed
- Prior art date
Links
- 230000012292 cell migration Effects 0.000 title abstract 2
- 238000010232 migration assay Methods 0.000 title abstract 2
- 229940122444 Chemokine receptor antagonist Drugs 0.000 abstract 1
- 239000002559 chemokine receptor antagonist Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Spectrometry And Color Measurement (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29668201P | 2001-06-07 | 2001-06-07 | |
| US10/154,399 US7282338B2 (en) | 2001-06-07 | 2002-05-22 | Cell migration assay |
| PCT/US2002/016325 WO2002101350A2 (en) | 2001-06-07 | 2002-05-22 | Cell migration assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1417488T3 true DK1417488T3 (da) | 2007-03-05 |
Family
ID=26851415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02739361T DK1417488T3 (da) | 2001-06-07 | 2002-05-22 | Cellemigrasionsassay |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7282338B2 (da) |
| EP (2) | EP1717583A3 (da) |
| JP (2) | JP4233092B2 (da) |
| KR (2) | KR100635703B1 (da) |
| AT (1) | ATE347695T1 (da) |
| CA (1) | CA2449628C (da) |
| DE (1) | DE60216606T2 (da) |
| DK (1) | DK1417488T3 (da) |
| ES (1) | ES2274041T3 (da) |
| WO (1) | WO2002101350A2 (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1417488T3 (da) * | 2001-06-07 | 2007-03-05 | Chemocentryx Inc | Cellemigrasionsassay |
| WO2004024075A2 (en) * | 2002-09-11 | 2004-03-25 | Medical College Of Georgia Research Institute, Inc. | Chemokine receptor antagonists as therapeutic agents |
| WO2004045526A2 (en) * | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms |
| AU2003298661B2 (en) | 2002-11-18 | 2007-05-10 | Chemocentryx, Inc. | Aryl sulfonamides |
| US20080085554A1 (en) * | 2004-02-13 | 2008-04-10 | Norio Nakatsuji | Culture Medium for Culturing Feeder Cells for Embryonic Stem Cells Culture and the Prepared Feeder Cells |
| US7622583B2 (en) | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
| WO2006076644A2 (en) | 2005-01-14 | 2006-07-20 | Chemocentryx, Inc. | Heteroaryl sulfonamides and ccr2 |
| US8519135B2 (en) | 2006-07-14 | 2013-08-27 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2/CCR9 |
| AU2007275873B2 (en) | 2006-07-14 | 2012-06-14 | Chemocentryx, Inc. | Triazolyl phenyl benzenesulfonamides |
| EP2041282B1 (en) | 2006-07-18 | 2018-01-03 | Noxxon Pharma AG | Sdf-i binding nucleic acids |
| CN101820881B (zh) | 2007-07-12 | 2013-05-01 | 坎莫森特里克斯公司 | 作为ccr2调节剂用于治疗炎症的稠合杂芳基吡啶基和苯基苯磺酰胺 |
| CN101796188B (zh) * | 2007-08-06 | 2014-10-29 | 诺松制药股份公司 | Sdf-1结合核酸及其用途 |
| CN103108641B (zh) | 2010-09-09 | 2016-01-13 | 诺松制药股份公司 | Sdf-1结合性核酸及其在癌症治疗中的用途 |
| AR084141A1 (es) | 2010-11-19 | 2013-04-24 | Imai Toshio | Anticuerpos neutralizadores anti-ccl20 |
| CN104849377A (zh) * | 2015-01-29 | 2015-08-19 | 衢州市质量技术监督检测中心 | 一种气质法快速测定畜禽肉中β-兴奋剂的前处理方法 |
| EP4134080B1 (en) | 2016-11-23 | 2024-11-13 | ChemoCentryx, Inc. | Ccr2 inhibitors for use in treating renal diseases |
| JOP20190187A1 (ar) | 2017-02-03 | 2019-08-01 | Novartis Ag | مترافقات عقار جسم مضاد لـ ccr7 |
| US10758540B2 (en) | 2017-10-11 | 2020-09-01 | Chemocentryx, Inc. | Treatment of focal segmental glomerulosclerosis with CCR2 antagonists |
| US11995833B2 (en) | 2020-07-31 | 2024-05-28 | The Joan and Irwin Jacobs Technion-Cornell Institute | System and method for on-phase microscopy |
| CN121969930A (zh) * | 2023-07-07 | 2026-05-01 | 阿达尔塔有限公司 | 将受体占有率与cxcr4拮抗剂功效相关联 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5811128A (en) | 1986-10-24 | 1998-09-22 | Southern Research Institute | Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor |
| US5328470A (en) | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| US5284753A (en) | 1991-03-20 | 1994-02-08 | Neuro Probe, Inc. | Multiple-site chemotactic test apparatus and method |
| SE9600820D0 (sv) * | 1996-03-01 | 1996-03-01 | Pharmacia Ab | Antibodies and their use |
| US5928881A (en) * | 1996-07-11 | 1999-07-27 | Smithkline Beecham Corporation | Method of identifying agonists and antagonist for CC-CKR5 receptor |
| GB9617923D0 (en) * | 1996-08-28 | 1996-10-09 | Smithkline Beecham Plc | Novel receptor |
| US6153441A (en) * | 1998-02-17 | 2000-11-28 | Smithkline Beecham Corporation | Methods of screening for agonists and antagonists for human CCR7 receptor and CKβ-9 ligand and interaction thereof |
| US6312689B1 (en) | 1998-07-23 | 2001-11-06 | Millennium Pharmaceuticals, Inc. | Anti-CCR2 antibodies and methods of use therefor |
| US6649158B1 (en) * | 1998-10-15 | 2003-11-18 | Canji, Inc. | Methods and compositions to induce antitumor response |
| AU2030000A (en) | 1998-11-25 | 2000-06-13 | Cadus Pharmaceutical Corporation | Methods and compositions for identifying receptor effectors |
| US6329159B1 (en) * | 1999-03-11 | 2001-12-11 | Millennium Pharmaceuticals, Inc. | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
| AU4230900A (en) * | 1999-04-08 | 2000-10-23 | General Hospital Corporation, The | Purposeful movement of human migratory cells away from an agent source |
| DK1417488T3 (da) * | 2001-06-07 | 2007-03-05 | Chemocentryx Inc | Cellemigrasionsassay |
-
2002
- 2002-05-22 DK DK02739361T patent/DK1417488T3/da active
- 2002-05-22 EP EP06017100A patent/EP1717583A3/en not_active Withdrawn
- 2002-05-22 EP EP02739361A patent/EP1417488B1/en not_active Expired - Lifetime
- 2002-05-22 US US10/154,399 patent/US7282338B2/en not_active Expired - Lifetime
- 2002-05-22 KR KR1020067007834A patent/KR100635703B1/ko not_active Expired - Lifetime
- 2002-05-22 AT AT02739361T patent/ATE347695T1/de active
- 2002-05-22 ES ES02739361T patent/ES2274041T3/es not_active Expired - Lifetime
- 2002-05-22 DE DE60216606T patent/DE60216606T2/de not_active Expired - Lifetime
- 2002-05-22 JP JP2003504063A patent/JP4233092B2/ja not_active Expired - Lifetime
- 2002-05-22 CA CA002449628A patent/CA2449628C/en not_active Expired - Lifetime
- 2002-05-22 KR KR1020037015768A patent/KR100598309B1/ko not_active Expired - Lifetime
- 2002-05-22 WO PCT/US2002/016325 patent/WO2002101350A2/en not_active Ceased
-
2005
- 2005-01-24 US US11/041,858 patent/US20050186556A1/en not_active Abandoned
-
2007
- 2007-04-17 US US11/788,334 patent/US7396653B2/en not_active Expired - Lifetime
-
2008
- 2008-06-18 JP JP2008158580A patent/JP4340713B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002101350A3 (en) | 2004-03-11 |
| JP2005518184A (ja) | 2005-06-23 |
| KR100635703B1 (ko) | 2006-10-17 |
| DE60216606D1 (de) | 2007-01-18 |
| EP1717583A2 (en) | 2006-11-02 |
| ATE347695T1 (de) | 2006-12-15 |
| ES2274041T3 (es) | 2007-05-16 |
| US7282338B2 (en) | 2007-10-16 |
| JP4233092B2 (ja) | 2009-03-04 |
| KR100598309B1 (ko) | 2006-07-10 |
| EP1717583A3 (en) | 2007-10-10 |
| CA2449628C (en) | 2008-05-06 |
| US7396653B2 (en) | 2008-07-08 |
| EP1417488A4 (en) | 2004-07-14 |
| WO2002101350A2 (en) | 2002-12-19 |
| HK1065844A1 (en) | 2005-03-04 |
| JP4340713B2 (ja) | 2009-10-07 |
| KR20040012888A (ko) | 2004-02-11 |
| JP2009000113A (ja) | 2009-01-08 |
| CA2449628A1 (en) | 2002-12-19 |
| US20050186556A1 (en) | 2005-08-25 |
| EP1417488A2 (en) | 2004-05-12 |
| DE60216606T2 (de) | 2007-04-05 |
| EP1417488B1 (en) | 2006-12-06 |
| KR20060054488A (ko) | 2006-05-22 |
| US20070196855A1 (en) | 2007-08-23 |
| US20030017485A1 (en) | 2003-01-23 |
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