ATE347695T1 - Zellwanderungsassay - Google Patents
ZellwanderungsassayInfo
- Publication number
- ATE347695T1 ATE347695T1 AT02739361T AT02739361T ATE347695T1 AT E347695 T1 ATE347695 T1 AT E347695T1 AT 02739361 T AT02739361 T AT 02739361T AT 02739361 T AT02739361 T AT 02739361T AT E347695 T1 ATE347695 T1 AT E347695T1
- Authority
- AT
- Austria
- Prior art keywords
- cell migration
- migration assay
- discrimination
- kit
- directed
- Prior art date
Links
- 230000012292 cell migration Effects 0.000 title abstract 2
- 238000010232 migration assay Methods 0.000 title abstract 2
- 229940122444 Chemokine receptor antagonist Drugs 0.000 abstract 1
- 239000002559 chemokine receptor antagonist Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Spectrometry And Color Measurement (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29668201P | 2001-06-07 | 2001-06-07 | |
| US10/154,399 US7282338B2 (en) | 2001-06-07 | 2002-05-22 | Cell migration assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE347695T1 true ATE347695T1 (de) | 2006-12-15 |
Family
ID=26851415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02739361T ATE347695T1 (de) | 2001-06-07 | 2002-05-22 | Zellwanderungsassay |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7282338B2 (de) |
| EP (2) | EP1417488B1 (de) |
| JP (2) | JP4233092B2 (de) |
| KR (2) | KR100635703B1 (de) |
| AT (1) | ATE347695T1 (de) |
| CA (1) | CA2449628C (de) |
| DE (1) | DE60216606T2 (de) |
| DK (1) | DK1417488T3 (de) |
| ES (1) | ES2274041T3 (de) |
| WO (1) | WO2002101350A2 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE347695T1 (de) * | 2001-06-07 | 2006-12-15 | Chemocentryx Inc | Zellwanderungsassay |
| WO2004024075A2 (en) * | 2002-09-11 | 2004-03-25 | Medical College Of Georgia Research Institute, Inc. | Chemokine receptor antagonists as therapeutic agents |
| US7919083B2 (en) * | 2002-11-15 | 2011-04-05 | Morehouse School Of Medicine | Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms |
| AU2003298661B2 (en) | 2002-11-18 | 2007-05-10 | Chemocentryx, Inc. | Aryl sulfonamides |
| KR20060114381A (ko) * | 2004-02-13 | 2006-11-06 | 레프로셀 인코퍼레이티드 | 배아줄기세포용 피더세포 작성 배지 및 피더세포 |
| AU2006204750C1 (en) | 2005-01-14 | 2012-11-01 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
| US7622583B2 (en) | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
| US8519135B2 (en) | 2006-07-14 | 2013-08-27 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2/CCR9 |
| PL2046762T3 (pl) | 2006-07-14 | 2011-07-29 | Chemocentryx Inc | Triazolilofenylobenzenosulfonamidy |
| JP5380287B2 (ja) * | 2006-07-18 | 2014-01-08 | ノクソン・ファルマ・アクチエンゲゼルシャフト | Ｓｄｆ−１結合核酸 |
| CA2692761C (en) | 2007-07-12 | 2013-04-30 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesulfonamides as ccr2 modulators for the treament of inflammation |
| PT2190991T (pt) * | 2007-08-06 | 2019-12-16 | Noxxon Pharma Ag | Ácidos nucleicos que se ligam a sdf 1 e a sua utilização |
| SG188220A1 (en) | 2010-09-09 | 2013-04-30 | Noxxon Pharma Ag | Sdf-1 binding nucleic acids and the use thereof in cancer treatment |
| MX361929B (es) | 2010-11-19 | 2018-12-19 | Eisai R&D Man Co Ltd Star | Anticuerpos anti-ligando de quimiocina cc 20 (ccl20) neutralizantes. |
| CN104849377A (zh) * | 2015-01-29 | 2015-08-19 | 衢州市质量技术监督检测中心 | 一种气质法快速测定畜禽肉中β-兴奋剂的前处理方法 |
| IL294410B2 (en) | 2016-11-23 | 2024-02-01 | Chemocentryx Inc | A method for the treatment of focal segmental tuberous sclerosis |
| JOP20190187A1 (ar) | 2017-02-03 | 2019-08-01 | Novartis Ag | مترافقات عقار جسم مضاد لـ ccr7 |
| MX386699B (es) | 2017-10-11 | 2025-03-19 | Chemocentryx Inc | Tratamiento de glomerulosclerosis segmentaria focal con antagonistas ccr2 |
| US11995833B2 (en) | 2020-07-31 | 2024-05-28 | The Joan and Irwin Jacobs Technion-Cornell Institute | System and method for on-phase microscopy |
| EP4740013A1 (de) * | 2023-07-07 | 2026-05-13 | AdAlta Limited | Verbindung der rezeptorbelegung mit der wirksamkeit von cxcr4-antagonisten |
| KR102990665B1 (ko) * | 2024-09-19 | 2026-07-15 | 부산대학교 산학협력단 | Ccl5를 포함하는 골수 유래 줄기세포의 활성화 촉진용 조성물 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US6024983A (en) | 1986-10-24 | 2000-02-15 | Southern Research Institute | Composition for delivering bioactive agents for immune response and its preparation |
| US5328470A (en) | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| US5284753A (en) | 1991-03-20 | 1994-02-08 | Neuro Probe, Inc. | Multiple-site chemotactic test apparatus and method |
| SE9600820D0 (sv) * | 1996-03-01 | 1996-03-01 | Pharmacia Ab | Antibodies and their use |
| US5928881A (en) * | 1996-07-11 | 1999-07-27 | Smithkline Beecham Corporation | Method of identifying agonists and antagonist for CC-CKR5 receptor |
| GB9617923D0 (en) * | 1996-08-28 | 1996-10-09 | Smithkline Beecham Plc | Novel receptor |
| US6153441A (en) * | 1998-02-17 | 2000-11-28 | Smithkline Beecham Corporation | Methods of screening for agonists and antagonists for human CCR7 receptor and CKβ-9 ligand and interaction thereof |
| US6312689B1 (en) | 1998-07-23 | 2001-11-06 | Millennium Pharmaceuticals, Inc. | Anti-CCR2 antibodies and methods of use therefor |
| US6649158B1 (en) * | 1998-10-15 | 2003-11-18 | Canji, Inc. | Methods and compositions to induce antitumor response |
| AU2030000A (en) | 1998-11-25 | 2000-06-13 | Cadus Pharmaceutical Corporation | Methods and compositions for identifying receptor effectors |
| US6329159B1 (en) | 1999-03-11 | 2001-12-11 | Millennium Pharmaceuticals, Inc. | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
| WO2000059941A1 (en) * | 1999-04-08 | 2000-10-12 | The General Hospital Corporation | Purposeful movement of human migratory cells away from an agent source |
| ATE347695T1 (de) * | 2001-06-07 | 2006-12-15 | Chemocentryx Inc | Zellwanderungsassay |
-
2002
- 2002-05-22 AT AT02739361T patent/ATE347695T1/de active
- 2002-05-22 CA CA002449628A patent/CA2449628C/en not_active Expired - Lifetime
- 2002-05-22 EP EP02739361A patent/EP1417488B1/de not_active Expired - Lifetime
- 2002-05-22 DE DE60216606T patent/DE60216606T2/de not_active Expired - Lifetime
- 2002-05-22 EP EP06017100A patent/EP1717583A3/de not_active Withdrawn
- 2002-05-22 KR KR1020067007834A patent/KR100635703B1/ko not_active Expired - Lifetime
- 2002-05-22 JP JP2003504063A patent/JP4233092B2/ja not_active Expired - Lifetime
- 2002-05-22 ES ES02739361T patent/ES2274041T3/es not_active Expired - Lifetime
- 2002-05-22 US US10/154,399 patent/US7282338B2/en not_active Expired - Lifetime
- 2002-05-22 WO PCT/US2002/016325 patent/WO2002101350A2/en not_active Ceased
- 2002-05-22 KR KR1020037015768A patent/KR100598309B1/ko not_active Expired - Lifetime
- 2002-05-22 DK DK02739361T patent/DK1417488T3/da active
-
2005
- 2005-01-24 US US11/041,858 patent/US20050186556A1/en not_active Abandoned
-
2007
- 2007-04-17 US US11/788,334 patent/US7396653B2/en not_active Expired - Lifetime
-
2008
- 2008-06-18 JP JP2008158580A patent/JP4340713B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20050186556A1 (en) | 2005-08-25 |
| US7396653B2 (en) | 2008-07-08 |
| CA2449628C (en) | 2008-05-06 |
| JP2005518184A (ja) | 2005-06-23 |
| EP1717583A2 (de) | 2006-11-02 |
| EP1417488A4 (de) | 2004-07-14 |
| JP2009000113A (ja) | 2009-01-08 |
| DE60216606D1 (de) | 2007-01-18 |
| CA2449628A1 (en) | 2002-12-19 |
| KR100635703B1 (ko) | 2006-10-17 |
| WO2002101350A3 (en) | 2004-03-11 |
| DE60216606T2 (de) | 2007-04-05 |
| HK1065844A1 (en) | 2005-03-04 |
| EP1417488B1 (de) | 2006-12-06 |
| WO2002101350A2 (en) | 2002-12-19 |
| US20030017485A1 (en) | 2003-01-23 |
| KR100598309B1 (ko) | 2006-07-10 |
| JP4233092B2 (ja) | 2009-03-04 |
| EP1417488A2 (de) | 2004-05-12 |
| KR20040012888A (ko) | 2004-02-11 |
| KR20060054488A (ko) | 2006-05-22 |
| JP4340713B2 (ja) | 2009-10-07 |
| US7282338B2 (en) | 2007-10-16 |
| ES2274041T3 (es) | 2007-05-16 |
| DK1417488T3 (da) | 2007-03-05 |
| EP1717583A3 (de) | 2007-10-10 |
| US20070196855A1 (en) | 2007-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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