DK1418942T3 - Poxvirus-holdige sammensætninger og fremgangsmåde til fremstilling deraf - Google Patents

Poxvirus-holdige sammensætninger og fremgangsmåde til fremstilling deraf

Info

Publication number
DK1418942T3
DK1418942T3 DK02796552T DK02796552T DK1418942T3 DK 1418942 T3 DK1418942 T3 DK 1418942T3 DK 02796552 T DK02796552 T DK 02796552T DK 02796552 T DK02796552 T DK 02796552T DK 1418942 T3 DK1418942 T3 DK 1418942T3
Authority
DK
Denmark
Prior art keywords
poxvirus
freeze
processes
preparation
containing compositions
Prior art date
Application number
DK02796552T
Other languages
Danish (da)
English (en)
Inventor
Karl Heller
Paul Howley
Ingmar Raethe
Original Assignee
Bavarian Nordic As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8160885&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1418942(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bavarian Nordic As filed Critical Bavarian Nordic As
Application granted granted Critical
Publication of DK1418942T3 publication Critical patent/DK1418942T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/275—Poxviridae, e.g. avipoxvirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK02796552T 2001-12-10 2002-11-28 Poxvirus-holdige sammensætninger og fremgangsmåde til fremstilling deraf DK1418942T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200101831 2001-12-10

Publications (1)

Publication Number Publication Date
DK1418942T3 true DK1418942T3 (da) 2005-11-28

Family

ID=8160885

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02796552T DK1418942T3 (da) 2001-12-10 2002-11-28 Poxvirus-holdige sammensætninger og fremgangsmåde til fremstilling deraf

Country Status (21)

Country Link
US (1) US7094412B2 (fr)
EP (1) EP1418942B1 (fr)
JP (1) JP4439263B2 (fr)
KR (1) KR20040074067A (fr)
CN (1) CN1296096C (fr)
AT (1) ATE300954T1 (fr)
AU (1) AU2002361962A1 (fr)
BR (1) BR0214822A (fr)
CA (1) CA2467365C (fr)
DE (1) DE60205388T2 (fr)
DK (1) DK1418942T3 (fr)
EA (1) EA006880B1 (fr)
ES (1) ES2247414T3 (fr)
HU (1) HUP0402179A3 (fr)
IL (2) IL161590A0 (fr)
MX (1) MXPA04005577A (fr)
NO (1) NO20042958L (fr)
NZ (1) NZ533302A (fr)
PL (1) PL213326B1 (fr)
UA (1) UA78738C2 (fr)
WO (1) WO2003053463A2 (fr)

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CN1207005C (zh) 2002-10-31 2005-06-22 威世药业（如皋）有限公司 含生物活性物质的兔皮和其用途
WO2006029467A1 (fr) * 2004-09-16 2006-03-23 Btf Pty Ltd Traitement de lyophylisation rapide
JP5138601B2 (ja) * 2005-11-21 2013-02-06 サノフィ パストゥール リミテッド 組換えウイルス安定化製剤
US8012738B2 (en) 2007-05-14 2011-09-06 Bavarian Nordic A/S Purification of vaccinia virus- and recombinant vaccinia virus-based vaccines
EP2148923B1 (fr) * 2007-05-18 2012-08-22 MedImmune, LLC Conservation de substances biologiquement actives par mousse lyophilisée
US8394385B2 (en) 2009-03-13 2013-03-12 Bavarian Nordic A/S Optimized early-late promoter combined with repeated vaccination favors cytotoxic T cell response against recombinant antigen in MVA vaccines
KR20120093941A (ko) 2009-10-08 2012-08-23 버베리안 노딕 에이/에스 인간에서 ｈｉｖ에 대한 광범위한 ｔ-세포 반응의 생성
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WO2012010280A1 (fr) 2010-07-20 2012-01-26 Bavarian Nordic A/S Procédé pour collecter des produits d'expression
WO2012011045A1 (fr) 2010-07-20 2012-01-26 Pfizer Inc. Vecteurs de parapoxvirus
DK2788021T3 (en) 2011-12-09 2017-04-10 Bavarian Nordic As POXVIRUS VECTOR FOR EXPRESSION OF BACTERIAL ANTIGENES CONNECTED TO TETANANOX INFRAGMENT C
WO2014009438A2 (fr) 2012-07-10 2014-01-16 Transgene Sa Vaccin antigénique mycobactérien
WO2014009433A1 (fr) 2012-07-10 2014-01-16 Transgene Sa Facteur de ressuscitation de mycobactéries convenant comme adjuvant
TWI690322B (zh) 2012-10-02 2020-04-11 法商傳斯堅公司 含病毒的調配物及其使用
DE102013004595A1 (de) 2013-03-15 2014-09-18 Emergent Product Development Germany Gmbh RSV-Impfstoffe
US10765731B2 (en) 2014-01-09 2020-09-08 Transgene Sa Fusion of heterooligomeric mycobacterial antigens
EP3116541B1 (fr) 2014-03-12 2019-11-27 Bavarian Nordic A/S Utilisation des émulsions d'eau et huile pour augmenter la réponse humorale avec mva
EP3552615B8 (fr) 2014-07-16 2022-03-02 Transgene Virus oncolytique pour l'expression de modulateurs de point de contrôle immunitaire
AU2015357225B2 (en) 2014-12-01 2020-04-09 Transgene Sa Stable liquid vaccinia virus formulations
ES3011733T3 (en) 2015-02-13 2025-04-08 Transgene Immunotherapeutic vaccine and antibody combination therapy
WO2016131945A1 (fr) 2015-02-20 2016-08-25 Transgene Sa Produit de combinaison modulateur de l'autophagie
FR3042121A1 (fr) 2015-10-08 2017-04-14 Jean-Marc Limacher Composition anti-tumorale
EP3452081A1 (fr) 2016-05-04 2019-03-13 Transgene SA Polythérapie avec un ligand de tlr9 cpg
TW201825674A (zh) 2016-09-09 2018-07-16 美商艾斯合顧問有限公司 表現雙特異性接合分子的溶瘤病毒
EP3522920A2 (fr) 2016-10-10 2019-08-14 Transgene SA Polythérapie à base d'un produit immunothérapeutique et de modulateurs de mdsc
WO2018091680A1 (fr) 2016-11-18 2018-05-24 Transgene Sa Vecteurs oncolytiques à base de la variole bovine
EP3562946B1 (fr) 2016-12-28 2021-11-24 Transgene SA Virus oncolytiques et molécules thérapeutiques
US11052147B2 (en) * 2017-05-15 2021-07-06 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
CA3061678A1 (fr) 2017-05-15 2018-11-22 Janssen Vaccines & Prevention B.V. Composition contenant un virus stable
BR112019026126A2 (pt) 2017-06-15 2020-06-30 Janssen Vaccines & Prevention B.V. vetores de poxvírus que codificam antígenos do hiv e métodos de uso dos mesmos
JP7334124B2 (ja) 2017-06-21 2023-08-28 トランジェーヌ 個別化ワクチン
WO2019020543A1 (fr) 2017-07-28 2019-01-31 Transgene Sa Virus oncolytiques exprimant des agents ciblant des modulateurs immunitaires métaboliques
WO2019170820A1 (fr) 2018-03-07 2019-09-12 Transgene Vecteurs de parapoxvirus
WO2020011754A1 (fr) 2018-07-09 2020-01-16 Transgene Virus de la vaccine chimériques
EP3847246A1 (fr) 2018-09-06 2021-07-14 Bavarian Nordic A/S Compositions de poxvirus améliorées en matière de stockage
EP3875119A4 (fr) 2018-10-30 2022-08-31 The University of Tokyo Virus oncolytique pour le traitement du cancer
WO2020136232A1 (fr) 2018-12-28 2020-07-02 Transgene Sa Protéine m2 à propriété immunosuppressive
CN113453712A (zh) 2018-12-28 2021-09-28 特兰斯吉恩股份有限公司 M2缺陷型痘病毒
JP7810554B2 (ja) 2019-03-01 2026-02-03 アケロイス バイオファーマ， インコーポレイテッド 抗原特異的免疫細胞におけるｃｄ１６０機能をモジュレートする方法およびその使用
WO2021180943A1 (fr) 2020-03-12 2021-09-16 Bavarian Nordic A/S Compositions améliorant la stabilité du poxvirus
US12029787B2 (en) 2020-07-01 2024-07-09 University Of Connecticut Method for generating recombinant poxviruses
CN116322740A (zh) 2020-07-13 2023-06-23 特兰斯吉恩股份有限公司 免疫抑制的治疗
WO2023025899A2 (fr) 2021-08-26 2023-03-02 Transgene Système de distribution pour cibler des gènes de la voie de l'interféron
WO2023213764A1 (fr) 2022-05-02 2023-11-09 Transgene Polypeptide de fusion comprenant un anti-pd-l1 sdab et un membre du tnfsf
WO2023213763A1 (fr) 2022-05-02 2023-11-09 Transgene Poxvirus codant pour un agent de liaison comprenant un sdab anti-pd-l1
US20250387463A1 (en) 2022-06-29 2025-12-25 Bavarian Nordic A/S Recombinant Modified saRNA (VRP) and Vaccinia Virus Ankara (MVA) Prime-Boost Regimen
CN119604618A (zh) 2022-06-29 2025-03-11 巴法里安诺迪克有限公司 爱泼斯坦-巴尔病毒疫苗
AU2023300419A1 (en) 2022-07-01 2025-01-02 Transgene Fusion protein comprising a surfactant-protein-d and a member of the tnfsf
WO2024038175A1 (fr) 2022-08-18 2024-02-22 Transgene Poxvirus chimériques
JP2026502453A (ja) 2023-01-12 2026-01-23 バヴァリアン・ノルディック・アクティーゼルスカブ がんワクチンのための組み換え改変ｓａＲＮＡ（ＶＲＰ）
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WO2024188801A1 (fr) 2023-03-10 2024-09-19 Bavarian Nordic A/S Utilisation de lignées cellulaires de caille pour production de poxvirus
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Also Published As

Publication number Publication date
DE60205388D1 (de) 2005-09-08
CA2467365A1 (fr) 2003-07-03
JP4439263B2 (ja) 2010-03-24
EA200400796A1 (ru) 2004-12-30
ES2247414T3 (es) 2006-03-01
EP1418942A2 (fr) 2004-05-19
AU2002361962A1 (en) 2003-07-09
WO2003053463A2 (fr) 2003-07-03
JP2005513109A (ja) 2005-05-12
US7094412B2 (en) 2006-08-22
WO2003053463A3 (fr) 2004-03-04
CN1296096C (zh) 2007-01-24
NO20042958L (no) 2004-07-09
DE60205388T2 (de) 2006-03-30
CA2467365C (fr) 2012-11-20
MXPA04005577A (es) 2005-04-19
PL213326B1 (pl) 2013-02-28
US20050019349A1 (en) 2005-01-27
CN1602205A (zh) 2005-03-30
EP1418942B1 (fr) 2005-08-03
HUP0402179A3 (en) 2012-09-28
HUP0402179A2 (hu) 2005-01-28
BR0214822A (pt) 2004-12-14
IL161590A0 (en) 2004-09-27
KR20040074067A (ko) 2004-08-21
EA006880B1 (ru) 2006-04-28
IL161590A (en) 2009-06-15
NZ533302A (en) 2005-11-25
PL369954A1 (en) 2005-05-02
UA78738C2 (en) 2007-04-25
ATE300954T1 (de) 2005-08-15
HK1071295A1 (en) 2005-07-15

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