DK1420788T3 - Nye piperidin-2,6-dion-bisulfatsalte og deres anvendelse til behandling af stressrelaterede emotionelle lidelser - Google Patents

Nye piperidin-2,6-dion-bisulfatsalte og deres anvendelse til behandling af stressrelaterede emotionelle lidelser

Info

Publication number: DK1420788T3
Authority: DK; Denmark
Prior art keywords: dione; stress; treatment; bisulphate; salts
Prior art date: 2001-08-28

Application number

DK02755226T

Other languages

English (en)

Inventor

Maurice Ward Gittos

Original Assignee

Prestwick Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-28

Filing date

2002-08-22

Publication date

2007-02-26

2002-08-22 Application filed by Prestwick Pharmaceuticals Inc filed Critical Prestwick Pharmaceuticals Inc

2007-02-26 Application granted granted Critical

2007-02-26 Publication of DK1420788T3 publication Critical patent/DK1420788T3/da

Links

238000011282 treatment Methods 0.000 title abstract 2
208000027534 Emotional disease Diseases 0.000 title 1
QAZNZIRWHIFTKI-UHFFFAOYSA-N piperidine-2,6-dione;sulfuric acid Chemical class OS(O)(=O)=O.O=C1CCCC(=O)N1 QAZNZIRWHIFTKI-UHFFFAOYSA-N 0.000 title 1
QAOWNCQODCNURD-UHFFFAOYSA-M bisulphate group Chemical group S([O-])(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 abstract 2
208000019901 Anxiety disease Diseases 0.000 abstract 1
208000019695 Migraine disease Diseases 0.000 abstract 1
208000019022 Mood disease Diseases 0.000 abstract 1
230000036506 anxiety Effects 0.000 abstract 1
210000003494 hepatocyte Anatomy 0.000 abstract 1
150000003840 hydrochlorides Chemical class 0.000 abstract 1
206010027599 migraine Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
201000002859 sleep apnea Diseases 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
230000004580 weight loss Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Immunology (AREA)
Addiction (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Otolaryngology (AREA)
Pulmonology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

DK02755226T 2001-08-28 2002-08-22 Nye piperidin-2,6-dion-bisulfatsalte og deres anvendelse til behandling af stressrelaterede emotionelle lidelser DK1420788T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0120821A GB2379216A (en)	2001-08-28	2001-08-28	Piperidin-2,6-dione salts useful for the treatment of stress-related affective disorders
PCT/GB2002/003869 WO2003020275A1 (en)	2001-08-28	2002-08-22	Novel piperidin-2,6-dione bisulphate salts and their use for the treatment of stress-related affective disorders

Publications (1)

Publication Number	Publication Date
DK1420788T3 true DK1420788T3 (da)	2007-02-26

Family

ID=9921084

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02755226T DK1420788T3 (da)	2001-08-28	2002-08-22	Nye piperidin-2,6-dion-bisulfatsalte og deres anvendelse til behandling af stressrelaterede emotionelle lidelser

Country Status (19)

Country	Link
US (1)	US7189742B2 (da)
EP (1)	EP1420788B1 (da)
JP (1)	JP2005502677A (da)
KR (1)	KR100906893B1 (da)
CN (1)	CN100506229C (da)
AT (1)	ATE347891T1 (da)
AU (1)	AU2002321522B2 (da)
BR (1)	BR0212175A (da)
CA (1)	CA2459009C (da)
CY (1)	CY1105979T1 (da)
DE (1)	DE60216776T2 (da)
DK (1)	DK1420788T3 (da)
ES (1)	ES2275898T3 (da)
GB (1)	GB2379216A (da)
IL (2)	IL160615A0 (da)
MX (1)	MXPA04001777A (da)
NZ (1)	NZ531345A (da)
PT (1)	PT1420788E (da)
WO (1)	WO2003020275A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0219639D0 (en) *	2002-08-22	2002-10-02	Prestwick Scient Capital Inc	Novel piperidin-2,6-dione salts and their use for the treatment of stress-related affective disorders
US7560861B2 (en)	2004-05-03	2009-07-14	Lg Electronics Inc.	Organic electro-luminescence display device with an organic electro-luminescence array and fabricating method thereof
EP1861102A1 (en) *	2005-03-15	2007-12-05	F. Hoffmann-Roche AG	Use of 2-anilino-3,4-dihydro-quinazolines as 5ht5a receptor antagonists
GB0518763D0 (en) *	2005-09-14	2005-10-19	Prestwick Pharmaceuticals Inc	Treatment of hypertension
KR101401612B1 (ko) *	2012-04-30	2014-06-02	재단법인 전남생물산업진흥원	석류 추출물을 유효성분으로 포함하는 스트레스성 질환의 치료 및 예방용 조성물
JP6910946B2 (ja)	2014-08-25	2021-07-28	アイミューンセラピューティクス，インコーポレイテッド	タマゴのタンパク質製剤およびその製造方法
EP3377050A4 (en)	2015-11-17	2019-11-20	The Trustees of Columbia University in the City of New York	PHARMACOLOGICAL PROPHYLACTICS AGAINST STRESS-INDUCED AFFECTIVE DISORDERS AND THEIR ASSOCIATED SYMPTOMS
US11622948B2 (en)	2017-11-09	2023-04-11	The Trustees Of Columbia University In The City Of New York	Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders
US11491120B2 (en)	2017-11-09	2022-11-08	The Trustees Of Columbia University In The City Of New York	Pharmacological prophylactics against stress-induced affective disorders in females

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3693729A (en) *	1970-02-19	1972-09-26	Global Marine Inc	Air cushion drilling vehicle
GB1455687A (en) *	1972-12-28	1976-11-17	Aspro Nicholas Ltd	Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines
GB2181346B (en) *	1985-09-11	1989-10-04	Nat Res Dev	Pharmaceutical compositions and medical uses of dioxopiperidine derivatives
DE3779991T2 (de) *	1986-09-08	1993-02-04	British Tech Group	Dioxopiperidin-derivate enthaltende anxiolytische zusammensetzungen.
US5104990A (en) *	1990-02-27	1992-04-14	G. D. Searle & Co.	Process for the preparation of 3-aryl-3-aminoalkyl-2,6-dioxohexahydropyridines

2001
- 2001-08-28 GB GB0120821A patent/GB2379216A/en not_active Withdrawn
2002
- 2002-08-22 CA CA2459009A patent/CA2459009C/en not_active Expired - Fee Related
- 2002-08-22 MX MXPA04001777A patent/MXPA04001777A/es active IP Right Grant
- 2002-08-22 ES ES02755226T patent/ES2275898T3/es not_active Expired - Lifetime
- 2002-08-22 NZ NZ531345A patent/NZ531345A/en not_active IP Right Cessation
- 2002-08-22 DK DK02755226T patent/DK1420788T3/da active
- 2002-08-22 DE DE60216776T patent/DE60216776T2/de not_active Expired - Lifetime
- 2002-08-22 KR KR1020047002723A patent/KR100906893B1/ko not_active Expired - Fee Related
- 2002-08-22 CN CNB028169123A patent/CN100506229C/zh not_active Expired - Fee Related
- 2002-08-22 WO PCT/GB2002/003869 patent/WO2003020275A1/en not_active Ceased
- 2002-08-22 US US10/486,925 patent/US7189742B2/en not_active Expired - Fee Related
- 2002-08-22 BR BR0212175-1A patent/BR0212175A/pt not_active IP Right Cessation
- 2002-08-22 IL IL16061502A patent/IL160615A0/xx active IP Right Grant
- 2002-08-22 JP JP2003524582A patent/JP2005502677A/ja active Pending
- 2002-08-22 PT PT02755226T patent/PT1420788E/pt unknown
- 2002-08-22 AT AT02755226T patent/ATE347891T1/de active
- 2002-08-22 EP EP02755226A patent/EP1420788B1/en not_active Expired - Lifetime
- 2002-08-22 AU AU2002321522A patent/AU2002321522B2/en not_active Ceased
2004
- 2004-02-26 IL IL160615A patent/IL160615A/en not_active IP Right Cessation
2007
- 2007-02-01 CY CY20071100144T patent/CY1105979T1/el unknown

Also Published As

Publication number	Publication date
ATE347891T1 (de)	2007-01-15
AU2002321522B2 (en)	2006-10-12
CA2459009A1 (en)	2003-03-13
PT1420788E (pt)	2007-03-30
GB2379216A (en)	2003-03-05
CN100506229C (zh)	2009-07-01
KR100906893B1 (ko)	2009-07-08
US20040249159A1 (en)	2004-12-09
EP1420788B1 (en)	2006-12-13
DE60216776T2 (de)	2007-10-04
CA2459009C (en)	2010-04-06
IL160615A (en)	2008-08-07
US7189742B2 (en)	2007-03-13
WO2003020275A1 (en)	2003-03-13
IL160615A0 (en)	2004-07-25
KR20040031000A (ko)	2004-04-09
MXPA04001777A (es)	2004-11-22
CY1105979T1 (el)	2011-04-06
DE60216776D1 (de)	2007-01-25
ES2275898T3 (es)	2007-06-16
NZ531345A (en)	2005-07-29
CN1549715A (zh)	2004-11-24
JP2005502677A (ja)	2005-01-27
GB0120821D0 (en)	2001-10-17
BR0212175A (pt)	2004-07-20
EP1420788A1 (en)	2004-05-26

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CY1105979T1 (el)	2011-04-06	Νεα οξινα θειικα αλατα πιπepιδινο-2,6-διονων και η χρηση τους για την αντιμετωπιση σχετιζομενων με το στρες συναισθηματικων διαταραχων
BR0214309A (pt)	2004-10-13	Derivados aril-1,4-pirazina substituìdos
DK1395567T3 (da)	2009-04-06	4-(phenylpiperazinylmethyl)-benzamidderivater og deres anvendelse til behandling af smerte, angst eller mavetarmslidelser
DK1252144T3 (da)	2010-04-19	Substituerede glutarimider og deres anvendelse som inhibitorer af IL-12-produktionen
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NO20035116D0 (no)	2003-11-17	4-(fenylpiperidin-4-yliden-metyl)-benzamidderivater og deres anvendelse forbehandling av smerte, angst eller gastrointestinale forstyrrelser
DK1539160T3 (da)	2006-10-09	Piperidin-2,6-dion-pamoatsalte og deres anvendelse til behandling af stressrelaterede emotionelle lidelser
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DK1254905T3 (da)	2004-03-29	4-(2-pyridyl)piperiziner med 5HT7 receptoragonistaktivitet
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ATE313528T1 (de)	2006-01-15	4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen
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