DK1420788T3 - Nye piperidin-2,6-dion-bisulfatsalte og deres anvendelse til behandling af stressrelaterede emotionelle lidelser - Google Patents
Nye piperidin-2,6-dion-bisulfatsalte og deres anvendelse til behandling af stressrelaterede emotionelle lidelserInfo
- Publication number
- DK1420788T3 DK1420788T3 DK02755226T DK02755226T DK1420788T3 DK 1420788 T3 DK1420788 T3 DK 1420788T3 DK 02755226 T DK02755226 T DK 02755226T DK 02755226 T DK02755226 T DK 02755226T DK 1420788 T3 DK1420788 T3 DK 1420788T3
- Authority
- DK
- Denmark
- Prior art keywords
- dione
- stress
- treatment
- bisulphate
- salts
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 2
- 208000027534 Emotional disease Diseases 0.000 title 1
- QAZNZIRWHIFTKI-UHFFFAOYSA-N piperidine-2,6-dione;sulfuric acid Chemical class OS(O)(=O)=O.O=C1CCCC(=O)N1 QAZNZIRWHIFTKI-UHFFFAOYSA-N 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-M bisulphate group Chemical group S([O-])(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000019022 Mood disease Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 210000003494 hepatocyte Anatomy 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 201000002859 sleep apnea Diseases 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 230000004580 weight loss Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0120821A GB2379216A (en) | 2001-08-28 | 2001-08-28 | Piperidin-2,6-dione salts useful for the treatment of stress-related affective disorders |
| PCT/GB2002/003869 WO2003020275A1 (en) | 2001-08-28 | 2002-08-22 | Novel piperidin-2,6-dione bisulphate salts and their use for the treatment of stress-related affective disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1420788T3 true DK1420788T3 (da) | 2007-02-26 |
Family
ID=9921084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02755226T DK1420788T3 (da) | 2001-08-28 | 2002-08-22 | Nye piperidin-2,6-dion-bisulfatsalte og deres anvendelse til behandling af stressrelaterede emotionelle lidelser |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7189742B2 (da) |
| EP (1) | EP1420788B1 (da) |
| JP (1) | JP2005502677A (da) |
| KR (1) | KR100906893B1 (da) |
| CN (1) | CN100506229C (da) |
| AT (1) | ATE347891T1 (da) |
| AU (1) | AU2002321522B2 (da) |
| BR (1) | BR0212175A (da) |
| CA (1) | CA2459009C (da) |
| CY (1) | CY1105979T1 (da) |
| DE (1) | DE60216776T2 (da) |
| DK (1) | DK1420788T3 (da) |
| ES (1) | ES2275898T3 (da) |
| GB (1) | GB2379216A (da) |
| IL (2) | IL160615A0 (da) |
| MX (1) | MXPA04001777A (da) |
| NZ (1) | NZ531345A (da) |
| PT (1) | PT1420788E (da) |
| WO (1) | WO2003020275A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0219639D0 (en) * | 2002-08-22 | 2002-10-02 | Prestwick Scient Capital Inc | Novel piperidin-2,6-dione salts and their use for the treatment of stress-related affective disorders |
| US7560861B2 (en) | 2004-05-03 | 2009-07-14 | Lg Electronics Inc. | Organic electro-luminescence display device with an organic electro-luminescence array and fabricating method thereof |
| JP4774436B2 (ja) * | 2005-03-15 | 2011-09-14 | エフ.ホフマン−ラ ロシュ アーゲー | 5ht5aレセプターアンタゴニストとしての2−アニリノ−3,4−ジヒドロ−キナゾリンの使用 |
| GB0518763D0 (en) * | 2005-09-14 | 2005-10-19 | Prestwick Pharmaceuticals Inc | Treatment of hypertension |
| KR101401612B1 (ko) * | 2012-04-30 | 2014-06-02 | 재단법인 전남생물산업진흥원 | 석류 추출물을 유효성분으로 포함하는 스트레스성 질환의 치료 및 예방용 조성물 |
| AU2015306683B2 (en) * | 2014-08-25 | 2021-11-25 | Societe Des Produits Nestle S.A. | Egg protein formulations and methods of manufacture thereof |
| EP3377050A4 (en) | 2015-11-17 | 2019-11-20 | The Trustees of Columbia University in the City of New York | PHARMACOLOGICAL PROPHYLACTICS AGAINST STRESS-INDUCED AFFECTIVE DISORDERS AND THEIR ASSOCIATED SYMPTOMS |
| US11622948B2 (en) | 2017-11-09 | 2023-04-11 | The Trustees Of Columbia University In The City Of New York | Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders |
| US11491120B2 (en) | 2017-11-09 | 2022-11-08 | The Trustees Of Columbia University In The City Of New York | Pharmacological prophylactics against stress-induced affective disorders in females |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3693729A (en) * | 1970-02-19 | 1972-09-26 | Global Marine Inc | Air cushion drilling vehicle |
| GB1455687A (en) * | 1972-12-28 | 1976-11-17 | Aspro Nicholas Ltd | Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines |
| EP0452765B1 (en) * | 1985-09-11 | 1999-10-20 | Btg International Limited | Pharmaceutical composition and medical uses of dioxopiperidine derivatives, especially as immune response potentiators, antiviral and antibacterial agents |
| GB2196251B (en) * | 1986-09-08 | 1990-07-04 | Nat Res Dev | Anxiolytic compositions containing dioxopiperidine derivatives |
| US5104990A (en) * | 1990-02-27 | 1992-04-14 | G. D. Searle & Co. | Process for the preparation of 3-aryl-3-aminoalkyl-2,6-dioxohexahydropyridines |
-
2001
- 2001-08-28 GB GB0120821A patent/GB2379216A/en not_active Withdrawn
-
2002
- 2002-08-22 CA CA2459009A patent/CA2459009C/en not_active Expired - Fee Related
- 2002-08-22 DK DK02755226T patent/DK1420788T3/da active
- 2002-08-22 CN CNB028169123A patent/CN100506229C/zh not_active Expired - Fee Related
- 2002-08-22 JP JP2003524582A patent/JP2005502677A/ja active Pending
- 2002-08-22 AT AT02755226T patent/ATE347891T1/de active
- 2002-08-22 PT PT02755226T patent/PT1420788E/pt unknown
- 2002-08-22 EP EP02755226A patent/EP1420788B1/en not_active Expired - Lifetime
- 2002-08-22 MX MXPA04001777A patent/MXPA04001777A/es active IP Right Grant
- 2002-08-22 AU AU2002321522A patent/AU2002321522B2/en not_active Ceased
- 2002-08-22 BR BR0212175-1A patent/BR0212175A/pt not_active IP Right Cessation
- 2002-08-22 WO PCT/GB2002/003869 patent/WO2003020275A1/en not_active Ceased
- 2002-08-22 KR KR1020047002723A patent/KR100906893B1/ko not_active Expired - Fee Related
- 2002-08-22 US US10/486,925 patent/US7189742B2/en not_active Expired - Fee Related
- 2002-08-22 DE DE60216776T patent/DE60216776T2/de not_active Expired - Lifetime
- 2002-08-22 IL IL16061502A patent/IL160615A0/xx active IP Right Grant
- 2002-08-22 NZ NZ531345A patent/NZ531345A/en not_active IP Right Cessation
- 2002-08-22 ES ES02755226T patent/ES2275898T3/es not_active Expired - Lifetime
-
2004
- 2004-02-26 IL IL160615A patent/IL160615A/en not_active IP Right Cessation
-
2007
- 2007-02-01 CY CY20071100144T patent/CY1105979T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1420788E (pt) | 2007-03-30 |
| NZ531345A (en) | 2005-07-29 |
| US20040249159A1 (en) | 2004-12-09 |
| GB0120821D0 (en) | 2001-10-17 |
| IL160615A0 (en) | 2004-07-25 |
| DE60216776T2 (de) | 2007-10-04 |
| GB2379216A (en) | 2003-03-05 |
| CN100506229C (zh) | 2009-07-01 |
| BR0212175A (pt) | 2004-07-20 |
| JP2005502677A (ja) | 2005-01-27 |
| CY1105979T1 (el) | 2011-04-06 |
| EP1420788B1 (en) | 2006-12-13 |
| CN1549715A (zh) | 2004-11-24 |
| WO2003020275A1 (en) | 2003-03-13 |
| MXPA04001777A (es) | 2004-11-22 |
| AU2002321522B2 (en) | 2006-10-12 |
| US7189742B2 (en) | 2007-03-13 |
| DE60216776D1 (de) | 2007-01-25 |
| EP1420788A1 (en) | 2004-05-26 |
| IL160615A (en) | 2008-08-07 |
| KR100906893B1 (ko) | 2009-07-08 |
| ATE347891T1 (de) | 2007-01-15 |
| KR20040031000A (ko) | 2004-04-09 |
| CA2459009A1 (en) | 2003-03-13 |
| CA2459009C (en) | 2010-04-06 |
| ES2275898T3 (es) | 2007-06-16 |
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