DK1422236T3 - Syntesefremgangsmåde for perindopril og farmaceutisk acceptable salte heraf - Google Patents
Syntesefremgangsmåde for perindopril og farmaceutisk acceptable salte herafInfo
- Publication number
- DK1422236T3 DK1422236T3 DK03292865T DK03292865T DK1422236T3 DK 1422236 T3 DK1422236 T3 DK 1422236T3 DK 03292865 T DK03292865 T DK 03292865T DK 03292865 T DK03292865 T DK 03292865T DK 1422236 T3 DK1422236 T3 DK 1422236T3
- Authority
- DK
- Denmark
- Prior art keywords
- perindopril
- pharmaceutically acceptable
- acceptable salts
- synthesis procedure
- synthesis
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- IPVQLZZIHOAWMC-QXKUPLGCSA-N perindopril Chemical compound C1CCC[C@H]2C[C@@H](C(O)=O)N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H]21 IPVQLZZIHOAWMC-QXKUPLGCSA-N 0.000 title 1
- 229960002582 perindopril Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03292865A EP1422236B1 (fr) | 2003-11-19 | 2003-11-19 | Procédé de synthèse du perindopril et de ses sels pharmaceutiquement acceptables |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1422236T3 true DK1422236T3 (da) | 2007-06-11 |
Family
ID=32187327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03292865T DK1422236T3 (da) | 2003-11-19 | 2003-11-19 | Syntesefremgangsmåde for perindopril og farmaceutisk acceptable salte heraf |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1422236B1 (da) |
| AR (1) | AR047245A1 (da) |
| AT (1) | ATE353910T1 (da) |
| CY (1) | CY1106543T1 (da) |
| DE (1) | DE60311730T2 (da) |
| DK (1) | DK1422236T3 (da) |
| ES (1) | ES2282587T3 (da) |
| MY (1) | MY149837A (da) |
| PT (1) | PT1422236E (da) |
| SI (1) | SI1422236T1 (da) |
| WO (1) | WO2005054277A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006131828A1 (en) * | 2005-06-08 | 2006-12-14 | Aurobindo Pharma Limited | A process for the preparation of perindopril |
| PH12018502155B1 (en) | 2016-04-20 | 2024-03-27 | Servier Lab | Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid |
| CN107098949B (zh) * | 2017-04-20 | 2021-03-16 | 上药东英（江苏）药业有限公司 | 一种制备培哚普利叔丁胺盐的绿色合成新工艺 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2620709B1 (fr) * | 1987-09-17 | 1990-09-07 | Adir | Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese |
-
2003
- 2003-11-19 ES ES03292865T patent/ES2282587T3/es not_active Expired - Lifetime
- 2003-11-19 PT PT03292865T patent/PT1422236E/pt unknown
- 2003-11-19 DK DK03292865T patent/DK1422236T3/da active
- 2003-11-19 SI SI200330700T patent/SI1422236T1/sl unknown
- 2003-11-19 AT AT03292865T patent/ATE353910T1/de active
- 2003-11-19 DE DE60311730T patent/DE60311730T2/de not_active Expired - Lifetime
- 2003-11-19 EP EP03292865A patent/EP1422236B1/fr not_active Expired - Lifetime
-
2004
- 2004-11-18 MY MYPI20044784A patent/MY149837A/en unknown
- 2004-11-18 WO PCT/FR2004/002937 patent/WO2005054277A1/fr not_active Ceased
- 2004-11-18 AR ARP040104254A patent/AR047245A1/es unknown
-
2007
- 2007-04-26 CY CY20071100561T patent/CY1106543T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005054277A1 (fr) | 2005-06-16 |
| PT1422236E (pt) | 2007-05-31 |
| ES2282587T3 (es) | 2007-10-16 |
| CY1106543T1 (el) | 2012-01-25 |
| ATE353910T1 (de) | 2007-03-15 |
| EP1422236B1 (fr) | 2007-02-14 |
| AR047245A1 (es) | 2006-01-11 |
| MY149837A (en) | 2013-10-31 |
| DE60311730T2 (de) | 2007-12-06 |
| EP1422236A1 (fr) | 2004-05-26 |
| SI1422236T1 (sl) | 2007-06-30 |
| DE60311730D1 (de) | 2007-03-29 |
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