DK1427724T3 - Hidtil ukendt anvendelse af substituerede aminomethylchromaner - Google Patents

Hidtil ukendt anvendelse af substituerede aminomethylchromaner

Info

Publication number: DK1427724T3
Authority: DK; Denmark
Prior art keywords: hitherto unknown; substituted aminomethyl; unknown use; chromanes; aminomethyl chromanes
Prior art date: 2001-09-19

Application number

DK02767363T

Other languages

English (en)

Inventor

Ralf Devant

Frank Weber

Christoph Seyfried

Henning Boettcher

Gerd Bartoszyk

Hermann Russ

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-19

Filing date

2002-08-12

Publication date

2006-08-21

2002-08-12 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

2006-08-21 Application granted granted Critical

2006-08-21 Publication of DK1427724T3 publication Critical patent/DK1427724T3/da

Links

BSRHATGBRQMDRF-UHFFFAOYSA-N 3,4-dihydro-2h-chromen-2-ylmethanamine Chemical class C1=CC=C2OC(CN)CCC2=C1 BSRHATGBRQMDRF-UHFFFAOYSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Public Health (AREA)
Neurology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Indole Compounds (AREA)

DK02767363T 2001-09-19 2002-08-12 Hidtil ukendt anvendelse af substituerede aminomethylchromaner DK1427724T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01122377		2001-09-19

Publications (1)

Publication Number	Publication Date
DK1427724T3 true DK1427724T3 (da)	2006-08-21

Family

ID=8178662

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02767363T DK1427724T3 (da)	2001-09-19	2002-08-12	Hidtil ukendt anvendelse af substituerede aminomethylchromaner

Country Status (25)

Country	Link
US (1)	US7618988B2 (da)
EP (1)	EP1427724B1 (da)
JP (1)	JP4615857B2 (da)
KR (1)	KR100912911B1 (da)
CN (1)	CN100338060C (da)
AR (1)	AR036677A1 (da)
AT (1)	ATE325120T1 (da)
AU (1)	AU2002331229B2 (da)
BR (1)	BR0212555A (da)
CA (1)	CA2460696C (da)
CY (1)	CY1105118T1 (da)
DE (1)	DE60211186T2 (da)
DK (1)	DK1427724T3 (da)
ES (1)	ES2262840T3 (da)
HU (1)	HUP0401910A3 (da)
MX (1)	MXPA04002492A (da)
MY (1)	MY128882A (da)
PE (1)	PE20030428A1 (da)
PL (1)	PL208787B1 (da)
PT (1)	PT1427724E (da)
RU (1)	RU2322443C2 (da)
SI (1)	SI1427724T1 (da)
TW (1)	TWI244391B (da)
WO (1)	WO2003024960A1 (da)
ZA (1)	ZA200402855B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10318690B3 (de) *	2003-04-24	2004-11-11	Merck Patent Gmbh	Verfahren zur Herstellung von Nicotinaldehyden
JP2008530229A (ja)	2005-02-17	2008-08-07	ワイス	シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
EP1896021B1 (de) *	2005-06-21	2009-04-15	Merck Patent GmbH	Feste pharmazeutische zubereitung enthaltend (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chroman
FR2978916B1 (fr)	2011-08-10	2013-07-26	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
MY169068A (en) *	2012-04-18	2019-02-12	Contera Pharma Aps	Orally available pharmaceutical formulation suitable for improved management of movement disorders
FR3001894A1 (fr)	2013-02-08	2014-08-15	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
CN109689036B (zh)	2016-07-11	2026-06-19	康特拉医药股份有限公司	用于治疗早晨运动不能的脉冲药物输送系统

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5767132A (en) *	1980-10-07	1982-04-23	Nippon Steel Corp	Vertical type continuous annealing furnace having independently moving middle partition plate
DE4135474A1 (de) *	1991-10-28	1993-04-29	Bayer Ag	2-aminomethyl-chromane
SI9300097B (en) *	1992-02-27	2001-12-31	Janssen Pharmaceutica Nv	(benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
ATE256130T1 (de) *	1993-08-19	2003-12-15	Janssen Pharmaceutica Nv	Gefässverengende dihydrobenzopyranderivate
ES2169102T3 (es) *	1994-10-14	2002-07-01	Merck Patent Gmbh	(r)-(-)-2-(5-(4-fluorfenil)-3-piridilmetilaminometil)-cromano como agente activo sobre el sistema nervioso central.
US5585388A (en) *	1995-04-07	1996-12-17	Sibia Neurosciences, Inc.	Substituted pyridines useful as modulators of acetylcholine receptors
JP3204456B2 (ja) *	1995-12-21	2001-09-04	ファイザー・インコーポレーテッド	２，７―置換オクタヒドロ―ピロロ［１，２―ａ］ピラジン誘導体
US5756521A (en) *	1996-04-03	1998-05-26	American Home Products Corporation	Chroman-2-ylmethylamino derivatives
UA73981C2 (en) *	2000-03-10	2005-10-17	Merck Patent Gmbh	(r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit

2002
- 2002-08-12 DE DE60211186T patent/DE60211186T2/de not_active Expired - Lifetime
- 2002-08-12 HU HU0401910A patent/HUP0401910A3/hu unknown
- 2002-08-12 AT AT02767363T patent/ATE325120T1/de active
- 2002-08-12 RU RU2004112190/15A patent/RU2322443C2/ru not_active IP Right Cessation
- 2002-08-12 WO PCT/EP2002/009001 patent/WO2003024960A1/en not_active Ceased
- 2002-08-12 PT PT02767363T patent/PT1427724E/pt unknown
- 2002-08-12 US US10/489,960 patent/US7618988B2/en not_active Expired - Fee Related
- 2002-08-12 BR BR0212555-2A patent/BR0212555A/pt not_active IP Right Cessation
- 2002-08-12 PL PL369684A patent/PL208787B1/pl not_active IP Right Cessation
- 2002-08-12 MX MXPA04002492A patent/MXPA04002492A/es active IP Right Grant
- 2002-08-12 AU AU2002331229A patent/AU2002331229B2/en not_active Ceased
- 2002-08-12 ES ES02767363T patent/ES2262840T3/es not_active Expired - Lifetime
- 2002-08-12 KR KR1020047002484A patent/KR100912911B1/ko not_active Expired - Fee Related
- 2002-08-12 EP EP02767363A patent/EP1427724B1/en not_active Expired - Lifetime
- 2002-08-12 CN CNB028183266A patent/CN100338060C/zh not_active Expired - Fee Related
- 2002-08-12 SI SI200230351T patent/SI1427724T1/sl unknown
- 2002-08-12 CA CA2460696A patent/CA2460696C/en not_active Expired - Fee Related
- 2002-08-12 DK DK02767363T patent/DK1427724T3/da active
- 2002-08-12 JP JP2003528807A patent/JP4615857B2/ja not_active Expired - Fee Related
- 2002-08-13 TW TW091118183A patent/TWI244391B/zh not_active IP Right Cessation
- 2002-09-16 MY MYPI20023438A patent/MY128882A/en unknown
- 2002-09-17 PE PE2002000915A patent/PE20030428A1/es not_active Application Discontinuation
- 2002-09-18 AR ARP020103509A patent/AR036677A1/es unknown
2004
- 2004-04-15 ZA ZA200402855A patent/ZA200402855B/en unknown
2006
- 2006-07-28 CY CY20061101061T patent/CY1105118T1/el unknown

Also Published As

Publication number	Publication date
US7618988B2 (en)	2009-11-17
CY1105118T1 (el)	2009-11-04
RU2322443C2 (ru)	2008-04-20
KR20040044461A (ko)	2004-05-28
EP1427724A1 (en)	2004-06-16
SI1427724T1 (sl)	2006-10-31
MXPA04002492A (es)	2004-05-31
PL369684A1 (en)	2005-05-02
BR0212555A (pt)	2004-10-19
CA2460696A1 (en)	2003-03-27
HUP0401910A2 (hu)	2005-01-28
AU2002331229B2 (en)	2008-05-15
ATE325120T1 (de)	2006-06-15
CN1714089A (zh)	2005-12-28
PE20030428A1 (es)	2003-05-24
WO2003024960A1 (en)	2003-03-27
DE60211186D1 (de)	2006-06-08
CA2460696C (en)	2011-01-11
EP1427724B1 (en)	2006-05-03
AR036677A1 (es)	2004-09-29
TWI244391B (en)	2005-12-01
DE60211186T2 (de)	2007-01-18
ZA200402855B (en)	2005-01-14
CN100338060C (zh)	2007-09-19
ES2262840T3 (es)	2006-12-01
KR100912911B1 (ko)	2009-08-20
RU2004112190A (ru)	2005-05-10
US20060229339A1 (en)	2006-10-12
HUP0401910A3 (en)	2011-02-28
PT1427724E (pt)	2006-09-29
PL208787B1 (pl)	2011-06-30
MY128882A (en)	2007-02-28
JP4615857B2 (ja)	2011-01-19
JP2005527476A (ja)	2005-09-15

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