DK1432443T3 - Angiotensinpeptid-bærerkonjugater og anvendelser deraf - Google Patents

Angiotensinpeptid-bærerkonjugater og anvendelser deraf

Info

Publication number: DK1432443T3
Authority: DK; Denmark
Prior art keywords: conjugates; angiotensin; peptide carrier; carrier conjugates; angiotensin peptide
Prior art date: 2001-10-05

Application number

DK02800605T

Other languages

English (en)

Inventor

Martin Bachmann

Original Assignee

Cytos Biotechnology Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-05

Filing date

2002-10-07

Publication date

2009-05-04

2002-01-18 Priority claimed from US10/050,902 external-priority patent/US7264810B2/en

2002-10-07 Application filed by Cytos Biotechnology Ag filed Critical Cytos Biotechnology Ag

2002-10-07 Priority claimed from PCT/EP2002/011219 external-priority patent/WO2003031466A2/en

2009-05-04 Application granted granted Critical

2009-05-04 Publication of DK1432443T3 publication Critical patent/DK1432443T3/da

Links

108010064733 Angiotensins Proteins 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
102000005862 Angiotensin II Human genes 0.000 abstract 1
101800000734 Angiotensin-1 Proteins 0.000 abstract 1
102400000344 Angiotensin-1 Human genes 0.000 abstract 1
101800000733 Angiotensin-2 Proteins 0.000 abstract 1
102000004881 Angiotensinogen Human genes 0.000 abstract 1
108090001067 Angiotensinogen Proteins 0.000 abstract 1
102000015427 Angiotensins Human genes 0.000 abstract 1
CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
102100028255 Renin Human genes 0.000 abstract 1
108090000783 Renin Proteins 0.000 abstract 1
ORWYRWWVDCYOMK-HBZPZAIKSA-N angiotensin I Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C1=CC=C(O)C=C1 ORWYRWWVDCYOMK-HBZPZAIKSA-N 0.000 abstract 1
229950006323 angiotensin ii Drugs 0.000 abstract 1
230000008878 coupling Effects 0.000 abstract 1
238000010168 coupling process Methods 0.000 abstract 1
238000005859 coupling reaction Methods 0.000 abstract 1
230000002163 immunogen Effects 0.000 abstract 1
230000001024 immunotherapeutic effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
239000000813 peptide hormone Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
230000003252 repetitive effect Effects 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0013—Therapeutic immunisation against small organic molecules, e.g. cocaine, nicotine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Urology & Nephrology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Vascular Medicine (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Mycology (AREA)
Hospice & Palliative Care (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK02800605T 2001-10-05 2002-10-07 Angiotensinpeptid-bærerkonjugater og anvendelser deraf DK1432443T3 (da)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US32699801P	2001-10-05	2001-10-05
US33104501P	2001-11-07	2001-11-07
US10/050,902 US7264810B2 (en)	2001-01-19	2002-01-18	Molecular antigen array
PCT/IB2002/000166 WO2002056905A2 (en)	2001-01-19	2002-01-21	Molecular antigen array
US39663702P	2002-07-19	2002-07-19
PCT/EP2002/011219 WO2003031466A2 (en)	2001-10-05	2002-10-07	Angiotensin peptide-carrier conjugates and uses thereof

Publications (1)

Publication Number	Publication Date
DK1432443T3 true DK1432443T3 (da)	2009-05-04

Family

ID=32996249

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02800605T DK1432443T3 (da)	2001-10-05	2002-10-07	Angiotensinpeptid-bærerkonjugater og anvendelser deraf

Country Status (10)

Country	Link
EP (1)	EP2090319A3 (da)
JP (1)	JP2010189406A (da)
KR (1)	KR101015508B1 (da)
AT (1)	ATE421334T1 (da)
BR (1)	BR0213117A (da)
DE (1)	DE60230992D1 (da)
DK (1)	DK1432443T3 (da)
IL (1)	IL160286A0 (da)
MX (1)	MXPA04002644A (da)
PL (1)	PL369796A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9446120B2 (en) *	2011-04-15	2016-09-20	Osaka University	DNA vaccine
WO2016112921A1 (en)	2015-01-15	2016-07-21	University Of Copenhagen	Virus-like particle with efficient epitope display
EP3368068B1 (en)	2015-10-30	2020-11-18	University of Copenhagen	Virus like particle with efficient epitope display
US12194157B2 (en)	2020-04-09	2025-01-14	Finncure Oy	Carrier for targeted delivery to a host
FI20215508A1 (en)	2020-04-09	2021-10-10	Niemelae Erik Johan	Mimetic nanoparticles to prevent the spread of new coronaviruses and reduce the rate of infection

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US4722840A (en)	1984-09-12	1988-02-02	Chiron Corporation	Hybrid particle immunogens
US4918166A (en)	1987-04-10	1990-04-17	Oxford Gene Systems Limited	Particulate hybrid HIV antigens
NZ235315A (en)	1989-09-19	1991-09-25	Wellcome Found	Chimaeric hepadnavirus core antigen proteins and their construction
DE69120146T2 (de)	1990-01-12	1996-12-12	Cell Genesys Inc	Erzeugung xenogener antikörper
US5334394A (en)	1990-06-22	1994-08-02	The Regents Of The University Of California	Human immunodeficiency virus decoy
SE9003978D0 (sv)	1990-12-13	1990-12-13	Henrik Garoff	Dna expressionssystem baserade paa ett virus replikon
GB9101550D0 (en)	1991-01-24	1991-03-06	Mastico Robert A	Antigen-presenting chimaeric protein
GB9114003D0 (en)	1991-06-28	1991-08-14	Mastico Robert A	Chimaeric protein
GB9227068D0 (en)	1992-12-29	1993-02-24	British Bio Technology	Novel proteinaceous particles
WO1994017813A1 (en)	1993-02-08	1994-08-18	Paravax, Inc.	Defective sindbis virus vectors that express toxoplasma gondii p30 antigens
US6015686A (en)	1993-09-15	2000-01-18	Chiron Viagene, Inc.	Eukaryotic layered vector initiation systems
US5876727A (en)	1995-03-31	1999-03-02	Immulogic Pharmaceutical Corporation	Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
CN1185811A (zh)	1995-03-31	1998-06-24	H·沃尔夫	依赖于逆转录病毒样颗粒的抗原呈递系统
US5792462A (en)	1995-05-23	1998-08-11	University Of North Carolina At Chapel Hill	Alphavirus RNA replicon systems
ID18046A (id)	1996-08-20	1998-02-19	Takeda Chemical Industries Ltd	Senyawa siklik campuran, pembuatan dan penngunaannya.
US5770380A (en)	1996-09-13	1998-06-23	University Of Pittsburgh	Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold
EP1486505A1 (en) *	1997-06-24	2004-12-15	Proteus Molecular Design Limited	Angiotensin derivatives
CZ302092B6 (cs)	1998-02-12	2010-10-06	Immune Complex, Corporation	Konjugát upraveného jaderného proteinu hepatitidy B, jeho cástice, inokulum a zpusob indukce protilátek
SE9801923D0 (sv)	1998-05-29	1998-05-29	Independent Pharmaceutical Ab	Nicotine vaccine
DE69929232T2 (de) *	1998-10-21	2006-08-31	The United States Government As Represented By The Department Of Health And Human Services	Virusähnliche partikel zur induktion von autoantikörpern
MXPA01005389A (es) *	1998-11-30	2003-03-27	Cytos Biotechnology Ag	Presentacion molecular ordenada de antigenos, metodos de preparacion y uso.
DE60122300T2 (de)	2000-04-07	2007-08-30	The University Of Leeds	Hepatitis b kernprotein fusionsproteine
CA2407897A1 (en) *	2000-05-05	2001-11-15	Cytos Biotechnology Ag	Molecular antigen arrays and vaccines
AU2001266163B2 (en)	2000-06-22	2006-07-13	Celltech Pharmaceticals Limited	Modification of hepatitis b core antigen
US20030138769A1 (en)	2000-08-16	2003-07-24	Birkett Ashley J.	Immunogenic HBc chimer particles having enhanced stability
US7264810B2 (en)	2001-01-19	2007-09-04	Cytos Biotechnology Ag	Molecular antigen array

2002
- 2002-01-21 MX MXPA04002644A patent/MXPA04002644A/es active IP Right Grant
- 2002-01-21 BR BR0213117-0A patent/BR0213117A/pt not_active IP Right Cessation
- 2002-10-07 AT AT02800605T patent/ATE421334T1/de not_active IP Right Cessation
- 2002-10-07 DE DE60230992T patent/DE60230992D1/de not_active Expired - Lifetime
- 2002-10-07 DK DK02800605T patent/DK1432443T3/da active
- 2002-10-07 EP EP09150826A patent/EP2090319A3/en not_active Withdrawn
- 2002-10-07 IL IL16028602A patent/IL160286A0/xx not_active IP Right Cessation
- 2002-10-07 KR KR1020047002222A patent/KR101015508B1/ko not_active Expired - Fee Related
- 2002-10-07 PL PL02369796A patent/PL369796A1/xx not_active Application Discontinuation
2010
- 2010-04-01 JP JP2010085112A patent/JP2010189406A/ja active Pending

Also Published As

Publication number	Publication date
ATE421334T1 (de)	2009-02-15
DE60230992D1 (de)	2009-03-12
JP2010189406A (ja)	2010-09-02
IL160286A0 (en)	2004-07-25
EP2090319A2 (en)	2009-08-19
PL369796A1 (en)	2005-05-02
MXPA04002644A (es)	2004-07-08
EP2090319A3 (en)	2009-10-28
KR101015508B1 (ko)	2011-02-16
KR20050034573A (ko)	2005-04-14
BR0213117A (pt)	2004-09-21
HK1067057A1 (en)	2005-04-01

Publication	Publication Date	Title
WO2003031466A3 (en)	2003-10-23	Angiotensin peptide-carrier conjugates and uses thereof
MXPA03008715A (es)	2003-12-11	Reduccion de la inmunogenicidad de proteinas de fusion.
FR20C1016I1 (da)	2020-06-12
MXPA03006093A (es)	2005-02-14	Derivados de n(fenilsulfonil)glicina y su uso terapeutico.
EP2345671B8 (en)	2023-01-11	Optimized fc variants and methods for their generation
MY162525A (en)	2017-06-15	Process for concentration of antibodies and therapeutic products thereof
ATE542829T1 (de)	2012-02-15	Impfstoff
DK0918848T3 (da)	2007-04-10	Fremgangsmåder til at behandle kræftsygdomme og patogene infektioner ved anvendelse af antigenpræsenterende celler påfyldt med RNA
ES2291311T3 (es)	2008-03-01	3-cianoquinolinas, 3-ciano-1,6-naftiridinas y 3-ciano-1,7-naftiridinas como inhibidores de proteina quinasas.
DE60328108D1 (de)	2009-08-06	Iscom-zubereitung und ihre verwendung
MXPA04006059A (es)	2004-09-27	Preparacion liofilizada que contiene anticuerpos contra el receptor del factor de crecimiento epidermico.
TR200001946T2 (tr)	2000-11-21	Aşı
CY1108446T1 (el)	2014-04-09	Μη νευροτοξικοι παραγοντες ενεργοποιησης πλασμινογονου για την αντιμετωπιση αποπληξιας
MXPA04004814A (es)	2004-08-11	Metodos para descubrir ligandos.
ATE551069T1 (de)	2012-04-15	Mucin-fusionspolypeptid-vakzine, zusammensetzungen und ihre verwendung
YU61103A (sh)	2006-05-25	Postupci za produkciju supstituisanih 2-(2-piridilmetil) sulfinil-1h-benzimidazola
AU2002323221A1 (en)	2003-06-17	Process for manufacture of molecular sieves
AU2003242535A1 (en)	2003-11-11	Improved polysaccharide and glycoconjugate vaccines
DK1432443T3 (da)	2009-05-04	Angiotensinpeptid-bærerkonjugater og anvendelser deraf
EE200500012A (et)	2005-08-15	Peptiid-pähine passiivne immunoteraapia ateroskleroosi raviks
ATE262600T1 (de)	2004-04-15	Herstellung von aluminium-silizium-legierungen
MY138550A (en)	2009-06-30	Method for synthesis of perindopril and its pharmaceutically acceptable salts
WO2002068475A3 (es)	2002-10-31	Composicion farmaceutica de fragmentos f(ab)2 de anticuerpos y un proceso para su preparacion
ATE471990T1 (de)	2010-07-15	Transkutane immunisierung gegen papillomavirus mit virusähnlichen papillomaviruspartikeln
AU2003267551A1 (en)	2004-03-11	Thieno-pyrrole compounds as antagonists of gonadotropin releasing hormone