DK143388D0 - Anvendelse af substituerede alkylidendithio-bis-(substituerede)-phenoler til fremstilling af farmaceutiske praeparater til inhibering af interleukin-1-frigivelse hos pattedyr - Google Patents
Anvendelse af substituerede alkylidendithio-bis-(substituerede)-phenoler til fremstilling af farmaceutiske praeparater til inhibering af interleukin-1-frigivelse hos pattedyrInfo
- Publication number
- DK143388D0 DK143388D0 DK143388A DK143388A DK143388D0 DK 143388 D0 DK143388 D0 DK 143388D0 DK 143388 A DK143388 A DK 143388A DK 143388 A DK143388 A DK 143388A DK 143388 D0 DK143388 D0 DK 143388D0
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- alkylidendithio
- phenoles
- mammals
- bis
- Prior art date
Links
- 102000000589 Interleukin-1 Human genes 0.000 title 1
- 108010002352 Interleukin-1 Proteins 0.000 title 1
- 241000124008 Mammalia Species 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2658687A | 1987-03-17 | 1987-03-17 | |
| US2658687 | 1987-03-17 | ||
| US15157288A | 1988-02-18 | 1988-02-18 | |
| US15157288 | 1988-02-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK143388D0 true DK143388D0 (da) | 1988-03-16 |
| DK143388A DK143388A (da) | 1988-09-18 |
| DK175801B1 DK175801B1 (da) | 2005-02-28 |
Family
ID=26701419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198801433A DK175801B1 (da) | 1987-03-17 | 1988-03-16 | Anvendelse af substituerede alkylidendithio-bis-(substituerede)-phenoler til fremstilling af et lægemiddel til inhibering af interleukin-1-medierede virkninger bortset fra atherosklerose og/eller hyperlipidæmi |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0292660B1 (da) |
| JP (1) | JP2671129B2 (da) |
| KR (1) | KR960005704B1 (da) |
| AU (1) | AU602961B2 (da) |
| DE (1) | DE3869202D1 (da) |
| DK (1) | DK175801B1 (da) |
| ES (1) | ES2039489T3 (da) |
| GR (1) | GR3004108T3 (da) |
| IE (1) | IE60708B1 (da) |
| PH (1) | PH23885A (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4959392A (en) * | 1989-07-24 | 1990-09-25 | Merrell Dow Pharmaceuticals Inc. | Method of treating diabetes mellitus |
| AU651873B2 (en) * | 1991-03-18 | 1994-08-04 | Merrell Dow Pharmaceuticals Inc. | Method of inhibiting the progressive development of diabetes mellitus |
| FI951367A7 (fi) * | 1994-03-28 | 1995-09-29 | Japan Energy Corp | Puriinijohdannaiset ja tulehdustautien tukahduttajat (suppressantit) |
| CN1275596C (zh) * | 1997-05-14 | 2006-09-20 | 阿特罗吉尼克斯公司 | 普罗布考单酯在制备用于治疗心血管疾病和炎性疾病的药物中的应用 |
| EP1695959A1 (en) * | 1997-05-14 | 2006-08-30 | Atherogenics, Inc. | Compouds and methods for the inhibition of the expression of VCAM-1 |
| US6852878B2 (en) | 1998-05-14 | 2005-02-08 | Atherogenics, Inc. | Thioketals and thioethers for inhibiting the expression of VCAM-1 |
| US6670398B2 (en) | 1997-05-14 | 2003-12-30 | Atherogenics, Inc. | Compounds and methods for treating transplant rejection |
| AU2006202461B2 (en) * | 1997-05-14 | 2009-12-03 | Atherogenics, Inc. | Compositions and methods for the inhibition of the expression of VCAM-1 |
| WO1999001118A2 (en) | 1997-07-01 | 1999-01-14 | Atherogenics, Inc. | Antioxidant enhancement of therapy for hyperproliferative conditions |
| US6881860B2 (en) | 2000-04-11 | 2005-04-19 | Atherogenics, Inc. | Compounds and methods to increase plasma HDL cholesterol levels and improve HDL functionality |
| EP2139320A4 (en) | 2007-03-26 | 2010-09-08 | Salutria Pharmaceuticals Llc | METHODS AND COMPOSITIONS OF PROBUCOL DERIVATIVES FOR THE TREATMENT OF DIABETES |
| CN108299263B (zh) * | 2018-01-30 | 2020-12-01 | 北京德默高科医药技术有限公司 | 一种普罗布考衍生物及其制备方法与应用 |
-
1988
- 1988-03-15 ES ES198888104086T patent/ES2039489T3/es not_active Expired - Lifetime
- 1988-03-15 DE DE8888104086T patent/DE3869202D1/de not_active Expired - Lifetime
- 1988-03-15 EP EP88104086A patent/EP0292660B1/en not_active Expired - Lifetime
- 1988-03-16 IE IE78688A patent/IE60708B1/en not_active IP Right Cessation
- 1988-03-16 AU AU13160/88A patent/AU602961B2/en not_active Expired
- 1988-03-16 PH PH36644A patent/PH23885A/en unknown
- 1988-03-16 DK DK198801433A patent/DK175801B1/da not_active IP Right Cessation
- 1988-03-16 KR KR1019880002733A patent/KR960005704B1/ko not_active Expired - Lifetime
- 1988-03-17 JP JP63062074A patent/JP2671129B2/ja not_active Expired - Lifetime
-
1992
- 1992-03-19 GR GR920400463T patent/GR3004108T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0292660A2 (en) | 1988-11-30 |
| DK175801B1 (da) | 2005-02-28 |
| JP2671129B2 (ja) | 1997-10-29 |
| EP0292660B1 (en) | 1992-03-18 |
| IE60708B1 (en) | 1994-08-10 |
| EP0292660A3 (en) | 1990-03-28 |
| AU1316088A (en) | 1988-09-15 |
| PH23885A (en) | 1989-12-18 |
| ES2039489T3 (es) | 1993-10-01 |
| KR880010766A (ko) | 1988-10-24 |
| GR3004108T3 (da) | 1993-03-31 |
| KR960005704B1 (ko) | 1996-05-01 |
| AU602961B2 (en) | 1990-11-01 |
| JPS63258408A (ja) | 1988-10-25 |
| DK143388A (da) | 1988-09-18 |
| IE880786L (en) | 1988-09-17 |
| DE3869202D1 (de) | 1992-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |