DK1444206T3 - Substituerede benzo[b]azepin-2-on-forbindelser som analgetika - Google Patents

Substituerede benzo[b]azepin-2-on-forbindelser som analgetika

Info

Publication number: DK1444206T3
Authority: DK; Denmark
Prior art keywords: azepin; analgesics; compounds; substituted benzo; benzo
Prior art date: 2001-10-29

Application number

DK02781280T

Other languages

Danish (da)

English (en)

Inventor

Michael Sattlegger

Helmut Buschmann

Michael Przewosny

Werner Englberger

Babette-Yvonne Koegel

Hans Schick

Original Assignee

Gruenenthal Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-29

Filing date

2002-10-23

Publication date

2006-07-24

2002-10-23 Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh

2006-07-24 Application granted granted Critical

2006-07-24 Publication of DK1444206T3 publication Critical patent/DK1444206T3/da

Links

229940035676 analgesics Drugs 0.000 title 1
239000000730 antalgic agent Substances 0.000 title 1
DXZDEAJXVCLRLE-UHFFFAOYSA-N azepin-2-one Chemical class O=C1C=CC=CC=N1 DXZDEAJXVCLRLE-UHFFFAOYSA-N 0.000 title 1
125000005605 benzo group Chemical group 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

DK02781280T 2001-10-29 2002-10-23 Substituerede benzo[b]azepin-2-on-forbindelser som analgetika DK1444206T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10153348A DE10153348A1 (de)	2001-10-29	2001-10-29	Substituierte Benzo(b)azepin-2-on-Verbindungen

Publications (1)

Publication Number	Publication Date
DK1444206T3 true DK1444206T3 (da)	2006-07-24

Family

ID=7704098

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02781280T DK1444206T3 (da)	2001-10-29	2002-10-23	Substituerede benzo[b]azepin-2-on-forbindelser som analgetika

Country Status (15)

Country	Link
US (1)	US7041662B2 (pl)
EP (1)	EP1444206B1 (pl)
JP (1)	JP2005511570A (pl)
AR (1)	AR037124A1 (pl)
AT (1)	ATE320418T1 (pl)
CA (1)	CA2464191A1 (pl)
CY (1)	CY1105039T1 (pl)
DE (2)	DE10153348A1 (pl)
DK (1)	DK1444206T3 (pl)
ES (1)	ES2260487T3 (pl)
HU (1)	HUP0401762A2 (pl)
PE (1)	PE20030614A1 (pl)
PL (1)	PL369852A1 (pl)
PT (1)	PT1444206E (pl)
WO (1)	WO2003037873A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN100569076C (zh) *	2004-05-12	2009-12-16	拜尔作物科学有限公司	植物生长调节作用
UA87313C2 (ru) *	2004-05-12	2009-07-10	Байер Кропсайенс Аг	Применение производного конденсированного азепинона для регулирования роста растений, композиция на его основе и способ регулирования роста растений
SE531698C2 (sv)	2007-07-12	2009-07-07	Respiratorius Ab	Nya bronkdilaterande a,b-omättade amider
MY197231A (en)	2015-07-22	2023-06-06	Enanta Pharm Inc	Benzodiazepine derivatives as rsv inhibitors
CA3133300A1 (en)	2019-03-18	2020-09-24	Enanta Pharmaceuticals, Inc.	Benzodiazepine derivatives as rsv inhibitors
US11505558B1 (en)	2019-10-04	2022-11-22	Enanta Pharmaceuticals, Inc.	Antiviral heterocyclic compounds
CN112759546B (zh) *	2019-11-06	2022-08-26	复旦大学	3-(二甲氨基甲基)哌啶-4-醇衍生物及其制备方法和药物用途
CN112759544B (zh) *	2019-11-06	2022-08-26	复旦大学	3-(二甲氨基甲基)哌啶-4-醇衍生物制备方法和药物用途
CN112759545B (zh) *	2019-11-06	2022-12-13	复旦大学	3-(二甲氨基甲基)哌啶-4-醇类衍生物及其制备方法和药物用途
US12624004B2 (en)	2019-11-06	2026-05-12	Fudan University	Opioid receptor agonist, preparation method therefor and pharmaceutical use thereof
CN112759587B (zh) *	2019-11-06	2022-12-30	复旦大学	3-(二甲氨基甲基)哌啶-4-醇类衍生物及其制备方法和药物用途
WO2022086840A1 (en)	2020-10-19	2022-04-28	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as anti-viral agents
US12612412B2 (en)	2021-02-26	2026-04-28	Enanta Pharmaceuticals, Inc.	Antiviral heterocyclic compounds
AR129003A1 (es)	2022-04-07	2024-07-03	Enanta Pharm Inc	Compuestos heterocíclicos antivirales
WO2023211997A1 (en)	2022-04-27	2023-11-02	Enanta Pharmaceuticals, Inc.	Antiviral compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3475414A (en) *	1966-12-05	1969-10-28	Miles Lab	Tetrahydro-1-benzazepin-2(1h)-one derivatives
TW213901B (pl) *	1992-01-27	1993-10-01	Pfizer
DE19525137C2 (de) *	1995-07-11	2003-02-27	Gruenenthal Gmbh	6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe

2001
- 2001-10-29 DE DE10153348A patent/DE10153348A1/de not_active Withdrawn
2002
- 2002-10-23 DK DK02781280T patent/DK1444206T3/da active
- 2002-10-23 PL PL02369852A patent/PL369852A1/pl not_active Application Discontinuation
- 2002-10-23 DE DE50206096T patent/DE50206096D1/de not_active Expired - Fee Related
- 2002-10-23 HU HU0401762A patent/HUP0401762A2/hu unknown
- 2002-10-23 JP JP2003540155A patent/JP2005511570A/ja active Pending
- 2002-10-23 ES ES02781280T patent/ES2260487T3/es not_active Expired - Lifetime
- 2002-10-23 AT AT02781280T patent/ATE320418T1/de not_active IP Right Cessation
- 2002-10-23 PT PT02781280T patent/PT1444206E/pt unknown
- 2002-10-23 EP EP02781280A patent/EP1444206B1/de not_active Expired - Lifetime
- 2002-10-23 WO PCT/EP2002/011830 patent/WO2003037873A1/de not_active Ceased
- 2002-10-23 CA CA002464191A patent/CA2464191A1/en not_active Abandoned
- 2002-10-28 PE PE2002001056A patent/PE20030614A1/es not_active Application Discontinuation
- 2002-10-29 AR ARP020104098A patent/AR037124A1/es unknown
2004
- 2004-04-14 US US10/824,244 patent/US7041662B2/en not_active Expired - Fee Related
2006
- 2006-05-31 CY CY20061100687T patent/CY1105039T1/el unknown

Also Published As

Publication number	Publication date
CY1105039T1 (el)	2010-03-03
ES2260487T3 (es)	2006-11-01
HUP0401762A2 (hu)	2004-12-28
DE10153348A1 (de)	2003-05-08
PL369852A1 (pl)	2005-05-02
JP2005511570A (ja)	2005-04-28
PT1444206E (pt)	2006-07-31
PE20030614A1 (es)	2003-07-26
ATE320418T1 (de)	2006-04-15
US20040224938A1 (en)	2004-11-11
WO2003037873A1 (de)	2003-05-08
AR037124A1 (es)	2004-10-20
CA2464191A1 (en)	2003-05-08
EP1444206B1 (de)	2006-03-15
EP1444206A1 (de)	2004-08-11
US7041662B2 (en)	2006-05-09
DE50206096D1 (de)	2006-05-11

Publication	Publication Date	Title
DK1451192T3 (da)	2011-04-04	Ny krystallinsk forbindelse
DK1326858T3 (da)	2006-05-08	Piperidinforbindelser som anti-allergiske midler
IS6971A (is)	2003-09-29	Ný efnasambönd
IS6561A (is)	2002-09-20	Bensóamíð píperidín efnasambönd sem P-efnis mótlyf
NO20032236L (no)	2003-07-10	Laktamforbindelse
IS6024A (is)	2001-07-26	Ný efnasambönd
EE200200033A (et)	2003-02-17	Uued ühendid
AR027983A1 (es)	2003-04-23	Novedosos compuestos
IS6139A (is)	2001-11-01	Ný efnasambönd
ID29914A (id)	2001-10-25	Senyawa benzensulfonamida heterosiklik sebagai antagonis bradikinin
NO20032215L (no)	2003-07-16	Laktamforbindelse
PL369852A1 (pl)	2005-05-02	Podstawione związki benzo[b]azepin-2-onowe
IS6657A (is)	2002-12-17	Ný efnasambönd
AR028220A1 (es)	2003-04-30	Novedosos compuestos
IS6141A (is)	2001-11-01	Ný efnasambönd
DK1261588T3 (da)	2005-02-14	Imidazolforbindelser som alfa2-adrenoceptorantagonister
IS6122A (is)	2001-10-23	Setin benzólaktam efnasambönd
AR028399A1 (es)	2003-05-07	Nuevos compuestos
NO20021026D0 (no)	2002-03-01	Ny forbindelse F-15078
DK1380585T3 (da)	2005-03-07	Pyrazolopyridinon som mellemprodukt
SI1444206T1 (sl)	2006-08-31	Substituirane benzo(b)azepin-2-onske spojine kot analgetiki
SE0100629D0 (sv)	2001-02-23	New compounds
SE0104342D0 (sv)	2001-12-20	New compounds
SE0103437D0 (sv)	2001-10-16	New compounds
SE0101660D0 (sv)	2001-05-11	New compounds