DK1463731T3 - Dibenzodiazepinderivater, deres fremstilling og anvendelse - Google Patents

Dibenzodiazepinderivater, deres fremstilling og anvendelse

Info

Publication number: DK1463731T3
Authority: DK; Denmark
Prior art keywords: preparation; sup; dibenzodiazepine derivatives; dibenzodiazepine; derivatives
Prior art date: 2002-01-10

Application number

DK03729243T

Other languages

English (en)

Inventor

Wilfried Lubisch

Wilfried Braje

Thomas Subkowski

Wolfgang Wernet

Karla Drescher

Roland Grandel

Reinhold Muller

Original Assignee

Abbott Gmbh & Co Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-10

Filing date

2003-01-10

Publication date

2006-02-13

2003-01-10 Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg

2006-02-13 Application granted granted Critical

2006-02-13 Publication of DK1463731T3 publication Critical patent/DK1463731T3/da

Links

150000008533 dibenzodiazepines Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Oncology (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Communicable Diseases (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Psychiatry (AREA)
Hematology (AREA)
Tropical Medicine & Parasitology (AREA)
Hospice & Palliative Care (AREA)
AIDS & HIV (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)

DK03729243T 2002-01-10 2003-01-10 Dibenzodiazepinderivater, deres fremstilling og anvendelse DK1463731T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10/041,556 US7026311B2 (en)	2002-01-10	2002-01-10	Dibenzodiazepine derivatives, their preparation and use

Publications (1)

Publication Number	Publication Date
DK1463731T3 true DK1463731T3 (da)	2006-02-13

Family

ID=21917135

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03729243T DK1463731T3 (da)	2002-01-10	2003-01-10	Dibenzodiazepinderivater, deres fremstilling og anvendelse

Country Status (11)

Country	Link
US (1)	US7026311B2 (da)
EP (1)	EP1463731B1 (da)
JP (1)	JP4308017B2 (da)
AT (1)	ATE305472T1 (da)
AU (1)	AU2003235806A1 (da)
CA (1)	CA2472107C (da)
DE (1)	DE60301725T2 (da)
DK (1)	DK1463731T3 (da)
ES (1)	ES2249718T3 (da)
MX (1)	MXPA04006443A (da)
WO (1)	WO2003057699A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101616919B (zh) *	2006-12-28	2012-10-10	雅培制药有限公司	聚（adp核糖）聚合酶抑制剂
US7960376B2 (en)	2007-09-14	2011-06-14	Cara Therapeutics, Inc.	Benzo-fused heterocycles
EP3144311A4 (en)	2014-05-16	2018-01-03	Shionogi & Co., Ltd.	Tricyclic heterocyclic derivative having hiv replication-inhibiting effect
US10414750B2 (en)	2014-07-03	2019-09-17	Celgene Quanticel Research, Inc.	Inhibitors of lysine specific demethylase-1
MX2017015256A (es) *	2015-05-29	2018-02-19	Shionogi & Co	Derivados triciclicos que contienen nitrogeno que tienen actividad inhibidora de la replicacion del virus de inmunodeficiencia adquirida (vih).
JP6457696B2 (ja)	2015-07-23	2019-01-23	アンスティテュ・キュリＩｎｓｔｉｔｕｔＣｕｒｉｅ	癌を処置するためのＤｂａｉｔ分子とＰＡＲＰインヒビターとの組合せの使用
GB201519573D0 (en)	2015-11-05	2015-12-23	King S College London	Combination
WO2018162439A1 (en)	2017-03-08	2018-09-13	Onxeo	New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule
KR20200130856A (ko)	2018-03-13	2020-11-20	옹쎄오	암 치료에서 획득한 내성에 대한 디베이트 분자
WO2021148581A1 (en)	2020-01-22	2021-07-29	Onxeo	Novel dbait molecule and its use
KR20260030809A (ko)	2023-06-21	2026-03-06	테트라곤 바이오사이언시스 엘티디	Hr 능숙형 암을 치료하는 방법에 사용하기 위한 데옥시시티딘 유도체 및 parp 억제제를 포함하는 조합

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ECSP003637A (es)	1999-08-31	2002-03-25	Agouron Pharma	Inhibidores triciclicos de poli (adp-ribosa) polimerasas
KR20010087401A (ko)	1999-09-28	2001-09-15	스타르크, 카르크	아제피노인돌 유도체, 그의 제법 및 용도

2002
- 2002-01-10 US US10/041,556 patent/US7026311B2/en not_active Expired - Fee Related
2003
- 2003-01-10 MX MXPA04006443A patent/MXPA04006443A/es active IP Right Grant
- 2003-01-10 AT AT03729243T patent/ATE305472T1/de active
- 2003-01-10 EP EP03729243A patent/EP1463731B1/en not_active Expired - Lifetime
- 2003-01-10 ES ES03729243T patent/ES2249718T3/es not_active Expired - Lifetime
- 2003-01-10 DK DK03729243T patent/DK1463731T3/da active
- 2003-01-10 CA CA002472107A patent/CA2472107C/en not_active Expired - Fee Related
- 2003-01-10 AU AU2003235806A patent/AU2003235806A1/en not_active Abandoned
- 2003-01-10 JP JP2003558014A patent/JP4308017B2/ja not_active Expired - Fee Related
- 2003-01-10 WO PCT/EP2003/000192 patent/WO2003057699A1/en not_active Ceased
- 2003-01-10 DE DE60301725T patent/DE60301725T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US7026311B2 (en)	2006-04-11
US20030139394A1 (en)	2003-07-24
DE60301725D1 (de)	2006-02-09
ATE305472T1 (de)	2005-10-15
ES2249718T3 (es)	2006-04-01
DE60301725T2 (de)	2006-07-06
AU2003235806A1 (en)	2003-07-24
JP4308017B2 (ja)	2009-08-05
EP1463731B1 (en)	2005-09-28
MXPA04006443A (es)	2004-10-04
CA2472107A1 (en)	2003-07-17
JP2005516031A (ja)	2005-06-02
EP1463731A1 (en)	2004-10-06
CA2472107C (en)	2008-10-28
WO2003057699A1 (en)	2003-07-17

Publication	Publication Date	Title
NO20021379L (no)	2002-03-20	Benzodiazepin-derivater, fremstilling og anvendelse derav
BG105650A (en)	2002-02-28	Azepinoindole derivatives, the production and use thereof
DE602004008098D1 (de)	2007-09-20	Substituierte 2h-ä1,2,4ütriazoloä4,3-aüpyrazine als gsk-3-inhibitoren
BR0313330A (pt)	2005-06-14	Piperidina-ftalazonas substituìdas com pirrolidinadiona como inibidores de pde4
EA200501333A1 (ru)	2006-06-30	5,7-ДИАМИНОПИРАЗОЛО[4,3-d]ПИРИМИДИНЫ, ПОЛЕЗНЫЕ ПРИ ЛЕЧЕНИИ ГИПЕРТЕНЗИИ
CY1106969T1 (el)	2012-09-26	Αναστολεις dpp-iv
DE60012188D1 (de)	2004-08-19	Fungizide
SE9900100D0 (sv)	1999-01-15	New compounds
CY1105410T1 (el)	2010-04-28	Υποκατεστημενες 2-φαινυλοβενζιμιδαζολες, η παρασκευη και η εφαρμογη τους
ATE345349T1 (de)	2006-12-15	Purinderivate
PE20030061A1 (es)	2003-02-08	1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
DK1463731T3 (da)	2006-02-13	Dibenzodiazepinderivater, deres fremstilling og anvendelse
MY141011A (en)	2010-02-25	Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones
DK1313740T3 (da)	2006-04-03	Prodrugs af imidazopyridinderivater
SE0203303D0 (sv)	2002-11-07	Novel Compounds
MXPA05009282A (es)	2005-10-05	Derivados de anilina sustituidos.
ATE359283T1 (de)	2007-05-15	Substituierte pyrazinonverbindungen zur behandlung von entzündungen
EP1667976A4 (en)	2008-02-13	Isoquinolinone POTASSIUM CHANNEL INHIBITORS
UY27587A1 (es)	2003-07-31	Heterociclos terapéuticos
GB0229081D0 (en)	2003-01-15	Multifunctional cationic photoinitiators, their preparation and use
SE0203300D0 (sv)	2002-11-07	Novel Compounds
EA200301101A1 (ru)	2004-04-29	Производные пиперазина и их применение в качестве ингибиторов pde4
EA200600601A1 (ru)	2006-10-27	Производные аминопиридина в качестве ингибиторов индуцируемой no-синтазы
EA200600608A1 (ru)	2006-10-27	Производные имидазопиридина как ингибиторы индуцируемой no-синтазы
BR0317719A (pt)	2005-11-22	Derivados de fosforamida