DK1480671T3 - Rekombinante RSV-vitusekspressionssystemer og vacciner - Google Patents

Rekombinante RSV-vitusekspressionssystemer og vacciner

Info

Publication number
DK1480671T3
DK1480671T3 DK01986054T DK01986054T DK1480671T3 DK 1480671 T3 DK1480671 T3 DK 1480671T3 DK 01986054 T DK01986054 T DK 01986054T DK 01986054 T DK01986054 T DK 01986054T DK 1480671 T3 DK1480671 T3 DK 1480671T3
Authority
DK
Denmark
Prior art keywords
vitreous
vaccines
expression systems
recombinant rsv
present
Prior art date
Application number
DK01986054T
Other languages
Danish (da)
English (en)
Inventor
Hong Jin
Roderick Tang
Shengqiang Li
Martin Bryant
Original Assignee
Medimmune Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Vaccines Inc filed Critical Medimmune Vaccines Inc
Application granted granted Critical
Publication of DK1480671T3 publication Critical patent/DK1480671T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18561—Methods of inactivation or attenuation
    • C12N2760/18562—Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK01986054T 2000-11-28 2001-11-28 Rekombinante RSV-vitusekspressionssystemer og vacciner DK1480671T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72441600A 2000-11-28 2000-11-28
PCT/US2001/044819 WO2002044334A2 (en) 2000-11-28 2001-11-28 Recombinant rsv virus expression systems and vaccines

Publications (1)

Publication Number Publication Date
DK1480671T3 true DK1480671T3 (da) 2007-12-10

Family

ID=24910360

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01986054T DK1480671T3 (da) 2000-11-28 2001-11-28 Rekombinante RSV-vitusekspressionssystemer og vacciner

Country Status (11)

Country Link
EP (2) EP1480671B1 (de)
JP (2) JP4268407B2 (de)
AT (1) ATE369148T1 (de)
AU (2) AU3652202A (de)
CA (2) CA2430115C (de)
CY (1) CY1107786T1 (de)
DE (1) DE60129860T2 (de)
DK (1) DK1480671T3 (de)
ES (1) ES2291370T3 (de)
PT (1) PT1480671E (de)
WO (1) WO2002044334A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1480671B1 (de) * 2000-11-28 2007-08-08 MedImmune Vaccines, Inc. Rekombinante rsv-virus-expressionssysteme und -impfstoffe
SG149684A1 (en) 2001-01-19 2009-02-27 Vironovative Bv A virus causing respiratory tract illness in susceptible animals
KR20040071678A (ko) * 2001-09-28 2004-08-12 유니버시티 오브 사우스 플로리다 Ｒｓｖ 유전자 발현 백신
KR101076102B1 (ko) 2002-02-21 2011-10-21 비로노바티브 비.브이. 메타뉴모바이러스에서 유래한 이종성 항원을 포함하는재조합 파라인플루엔자 바이러스 발현 시스템 및 백신
AU2003295339B2 (en) * 2002-09-27 2009-03-26 Medimmune, Llc Functional mutations in respiratory syncytial virus
ATE469170T1 (de) 2003-03-28 2010-06-15 Medimmune Llc Zusammensetzungen und verfahren mit dem respiratory syncytial virus untergruppe b stamm 9320
CA2523319A1 (en) * 2003-04-25 2004-11-11 Medimmune Vaccines, Inc. Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus
US20140205620A1 (en) * 2011-06-01 2014-07-24 The Board Of Regents For Oklahoma State University Engineered respiratory syncytial viruses with control of cell-to-cell virus transmission for enhanced safety of live virus vaccines
AU2012317159B2 (en) * 2011-06-08 2016-10-06 Vishwas Joshi Two plasmid mammalian expression system
JP6132420B2 (ja) * 2011-10-25 2017-05-24 国立大学法人岐阜大学 変異狂犬病ウイルス合成・増殖方法、並びに狂犬病ワクチン製剤
AR106956A1 (es) 2015-12-11 2018-03-07 Us Health Cepas de virus sincitial respiratorio recombinante con mutaciones en el marco de lectura abierto (orf) m2-2 que proporcionan un rango de fenotipos de atenuación
CN115725657B (zh) * 2022-09-16 2024-06-04 中国科学院广州生物医药与健康研究院 一种节段化的水泡性口炎病毒载体及其制备方法和应用
CN117886950B (zh) * 2023-12-28 2024-11-26 复百澳(苏州)生物医药科技有限公司 呼吸道合胞病毒假病毒及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030054505A1 (en) * 1997-09-26 2003-03-20 Hong Jin Recombinant rsv expression systems and vaccines
CA2230033C (en) * 1995-09-27 2010-01-26 Peter L. Collins Production of infectious respiratory syncytial virus from cloned nucleotide sequences
EP0912724B1 (de) * 1996-07-15 2009-12-09 The Government of The United States of America, as represented by The Department of Health and Human Services Herstellung von attenuierten respiratorischen syncytialvirus-impfstoffen aus klonierten nukleotidsequenzen
WO2001004321A1 (en) * 1999-07-09 2001-01-18 The Government Of The United States Of America, As Represented By The Department Of Health And Human Services Production of attenuated respiratory syncytial virus vaccines involving modification of m2 orf2
EP1480671B1 (de) * 2000-11-28 2007-08-08 MedImmune Vaccines, Inc. Rekombinante rsv-virus-expressionssysteme und -impfstoffe

Also Published As

Publication number Publication date
AU3652202A (en) 2002-06-11
CA2430115A1 (en) 2002-06-06
DE60129860T2 (de) 2008-04-24
EP1480671A2 (de) 2004-12-01
JP2009028041A (ja) 2009-02-12
EP1920783A1 (de) 2008-05-14
CA2797703A1 (en) 2002-06-06
JP2004534514A (ja) 2004-11-18
JP4268407B2 (ja) 2009-05-27
PT1480671E (pt) 2007-11-20
WO2002044334A2 (en) 2002-06-06
AU2002236522B2 (en) 2007-10-25
DE60129860D1 (de) 2007-09-20
ES2291370T3 (es) 2008-03-01
EP1480671B1 (de) 2007-08-08
WO2002044334A3 (en) 2004-08-26
EP1480671A4 (de) 2005-06-01
CY1107786T1 (el) 2013-06-19
ATE369148T1 (de) 2007-08-15
CA2430115C (en) 2013-02-26

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