DK1485354T3 - Sulfonylamino-derivater som nye inhibitorer af histandeacetylase - Google Patents

Sulfonylamino-derivater som nye inhibitorer af histandeacetylase

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Publication number
DK1485354T3
DK1485354T3 DK03743874T DK03743874T DK1485354T3 DK 1485354 T3 DK1485354 T3 DK 1485354T3 DK 03743874 T DK03743874 T DK 03743874T DK 03743874 T DK03743874 T DK 03743874T DK 1485354 T3 DK1485354 T3 DK 1485354T3
Authority
DK
Denmark
Prior art keywords
histane
deacetylase
novel inhibitors
sulfonylamino derivatives
sulfonylamino
Prior art date
Application number
DK03743874T
Other languages
English (en)
Inventor
Emelen Kristof Van
Leo Jacobus Jozef Backx
Brandt Sven Franciscus Ann Van
Marc Gustaaf Celine J Verdonck
Winter Hans Louis Jos De
Patrick Rene Angibaud
Isabelle Noelle C Pilatte
Heusden Jimmy Arnorld Vivi Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1485354T3 publication Critical patent/DK1485354T3/da

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/402—1-aryl substituted, e.g. piretanide
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