DK148905C - Analogifremgangsmaade til fremstilling af lh-rh-analoge nonapeptidderivater - Google Patents

Analogifremgangsmaade til fremstilling af lh-rh-analoge nonapeptidderivater

Info

Publication number: DK148905C
Authority: DK; Denmark
Prior art keywords: nonapeptid; analogue; derivatives; preparation; analogy procedure
Prior art date: 1974-08-09

Application number

DK361875A

Other languages

Danish (da)

English (en)

Other versions

DK148905B (da

DK361875A (da

Inventor

Wolfgang Koenig

Rolf Geiger

Juergen Kurt Sandow

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-08-09

Filing date

1975-08-08

Publication date

1986-04-07

1975-08-08 Application filed by Hoechst Ag filed Critical Hoechst Ag

1976-02-10 Publication of DK361875A publication Critical patent/DK361875A/da

1983-09-26 Priority to DK439683A priority Critical patent/DK148906C/da

1985-11-11 Publication of DK148905B publication Critical patent/DK148905B/da

1986-04-07 Application granted granted Critical

1986-04-07 Publication of DK148905C publication Critical patent/DK148905C/da

Links

XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical class C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Immunology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DK361875A 1974-08-09 1975-08-08 Analogifremgangsmaade til fremstilling af lh-rh-analoge nonapeptidderivater DK148905C (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK439683A DK148906C (da)	1974-08-09	1983-09-26	Lh-rh-analoge nonapeptidderivater til diagnostisk anvendelse

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2438350		1974-08-09
DE2438350A DE2438350C3 (de)	1974-08-09	1974-08-09	Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (3)

Publication Number	Publication Date
DK361875A DK361875A (da)	1976-02-10
DK148905B DK148905B (da)	1985-11-11
DK148905C true DK148905C (da)	1986-04-07

Family

ID=5922833

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK361875A DK148905C (da)	1974-08-09	1975-08-08	Analogifremgangsmaade til fremstilling af lh-rh-analoge nonapeptidderivater

Country Status (15)

Country	Link
US (1)	US4024248A (fr)
JP (1)	JPS5761268B2 (fr)
AT (1)	AT364093B (fr)
BE (1)	BE832310A (fr)
CA (1)	CA1069888A (fr)
CH (1)	CH613186A5 (fr)
DE (1)	DE2438350C3 (fr)
DK (1)	DK148905C (fr)
FR (1)	FR2281132A1 (fr)
GB (1)	GB1523623A (fr)
IE (1)	IE41510B1 (fr)
IL (1)	IL47880A (fr)
LU (1)	LU73166A1 (fr)
NL (1)	NL182051C (fr)
SE (2)	SE424184B (fr)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2617646C2 (de) *	1976-04-22	1986-07-31	Hoechst Ag, 6230 Frankfurt	Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
GB1524747A (en) *	1976-05-11	1978-09-13	Ici Ltd	Polypeptide
DE2735515A1 (de) *	1977-08-06	1979-02-22	Hoechst Ag	Verwendung von lh-rh-peptiden als antikonzeptive
FR2450109B1 (fr) *	1977-11-08	1986-03-28	Roussel Uclaf	Nouvelle methode de traitement utilisant la lh-rh, ou des agonistes
US4234571A (en) *	1979-06-11	1980-11-18	Syntex (U.S.A.) Inc.	Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
IT1149971B (it) *	1979-06-11	1986-12-10	Syntex Inc	Derivati nonapeptide e decapeptide dell'ormone che rilascia l'ormone luteinizzante
DE3020941A1 (de) *	1980-06-03	1981-12-17	Hoechst Ag, 6000 Frankfurt	Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung
HU185535B (en) *	1982-05-25	1985-02-28	Mta Koezponti Hivatala	Process for preparing new gonadoliberin derivatives
HU187503B (en) *	1983-03-29	1986-01-28	Magyar Tudomanyos Akademia,Hu	Process for preparing gonadoliberine derivatives containing beta-aspartyl group
AT390066B (de) *	1983-03-29	1990-03-12	Richter Gedeon Vegyeszet	Verfahren zur herstellung von neuen gonadoliberin-derivaten
DE3411224A1 (de) *	1984-03-27	1985-10-10	Hoechst Ag, 6230 Frankfurt	Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren
US4760053A (en) *	1984-08-02	1988-07-26	Fernand Labrie	Combination therapy for selected sex steroid dependent cancers
US4666885A (en) *	1985-02-08	1987-05-19	Fernand Labrie	Combination therapy for treatment of female breast cancer
US4775660A (en) *	1984-08-02	1988-10-04	Fernand Labrie	Treatment of breast cancer by combination therapy
HU193093B (en) *	1985-04-16	1987-08-28	Innofinance	Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation
HU194280B (en) *	1985-10-22	1988-01-28	Richter Gedeon Vegyeszet	Process for producing new gonadoliberin analogues of high effectivity and pharmaceutical compositions containing them
EP0462189B1 (fr) *	1989-03-10	1995-09-27	Endorecherche Inc.	Therapie combinee pour le traitement de maladies sensibles a l'oestrogene
US5372996A (en) *	1989-03-10	1994-12-13	Endorecherche, Inc.	Method of treatment of androgen-related diseases
JPH0235232A (ja) *	1989-06-29	1990-02-05	Nhk Spring Co Ltd	気室と液室を有する圧力容器
AU5856090A (en) *	1989-07-07	1991-02-06	Endorecherche Inc.	Androgen derivatives for use in the inhibition of sex steroid activity
ES2189784T3 (es) *	1989-07-07	2003-07-16	Endorech Inc	Procedimiento para el tratamiento de enfermedades relacionadas con adrogenos.
CA2029018A1 (fr) *	1989-11-01	1991-05-02	Robert P. Millar	Analogues de l'hormone liberant de la gonadotrophine
JPH0474770U (fr) *	1990-10-31	1992-06-30
JPH07506575A (ja) *	1992-05-21	1995-07-20	アンドルシェルシュ・インコーポレイテッド	テストステロン５α−レダクターゼ活性の阻害剤
US6413536B1 (en)	1995-06-07	2002-07-02	Southern Biosystems, Inc.	High viscosity liquid controlled delivery system and medical or surgical device
US7833543B2 (en) *	1995-06-07	2010-11-16	Durect Corporation	High viscosity liquid controlled delivery system and medical or surgical device
CA2192782C (fr)	1995-12-15	2008-10-14	Nobuyuki Takechi	Production de microsphere
CA2192773C (fr)	1995-12-15	2008-09-23	Hiroaki Okada	Obtention d'une preparation a liberation prolongee pour injection
US20060025328A1 (en) *	1997-05-28	2006-02-02	Burns Patrick J	Compositions suitable for controlled release of the hormone GnRH and its analogs
US6051558A (en) *	1997-05-28	2000-04-18	Southern Biosystems, Inc.	Compositions suitable for controlled release of the hormone GnRH and its analogs
US6242421B1 (en)	1997-11-06	2001-06-05	Richard Lloyd Bowen	Methods for preventing and treating Alzheimer's disease
ES2154590B1 (es)	1999-05-20	2001-11-01	Lipotec Sa	Procedimiento de sintesis de peptidos en fase solida
AR023940A1 (es)	2000-05-03	2002-09-04	Eriochem Sa	Procedimiento para la produccion de microcapsulas de liberacion prolongada de peptidos solubles en agua
CA2451187C (fr)	2001-06-22	2012-08-14	Southern Biosystems, Inc.	Implants coaxiaux a liberation prolongee d'ordre 0
US20060287282A1 (en) *	2001-06-25	2006-12-21	Steiner Mitchell S	Compositions comprising a SARM ad GnRH agonist or a GnRH antagonist, and methods of use thereof
WO2003015820A1 (fr) *	2001-08-10	2003-02-27	Takeda Chemical Industries, Ltd.	Medicaments combines d'agoniste de la gnrh
EP1444988A4 (fr)	2001-11-13	2007-04-25	Takeda Pharmaceutical	Agents anticancer
US20030144203A1 (en) *	2001-12-19	2003-07-31	Voyager Pharmaceutical Corporation	Methods for slowing senescence and treating and preventing diseases associated with senescence
US20040001889A1 (en)	2002-06-25	2004-01-01	Guohua Chen	Short duration depot formulations
ATE482695T1 (de) *	2002-12-13	2010-10-15	Durect Corp	Orale darreichungsform mit flüssigen hochviskosen trägersystemen
GB0307777D0 (en) *	2003-04-04	2003-05-07	Medical Res Council	Conjugate compounds
BRPI0515372B8 (pt) *	2004-09-17	2021-05-25	Durect Corp	composição líquida para fornecer anestesia local prolongada após administração a um indivíduo, e, uso de bupivacaína, acetato isobutirato de sacarose e álcool benzílico
CA2594477C (fr)	2005-01-21	2016-07-12	Astex Therapeutics Limited	Composes pharmaceutiques
US20070027105A1 (en)	2005-07-26	2007-02-01	Alza Corporation	Peroxide removal from drug delivery vehicle
US20070106271A1 (en) *	2005-11-09	2007-05-10	Searete Llc, A Limited Liability Corporation	Remote control of substance delivery system
WO2008044041A1 (fr)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Combinaisons pharmaceutiques
WO2008044045A1 (fr)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Combinaisons pharmaceutiques
PL2117521T3 (pl)	2006-11-03	2012-11-30	Durect Corp	Transdermalne systemy dostarczania zawierające bupiwakainę
WO2009075782A1 (fr) *	2007-12-06	2009-06-18	Durect Corporation	Procédés utiles dans le traitement de la douleur, d'états rhumatismaux ou d'inflammations associées à un état chronique
US20100260844A1 (en)	2008-11-03	2010-10-14	Scicinski Jan J	Oral pharmaceutical dosage forms
RU2444525C2 (ru) *	2010-06-09	2012-03-10	Закрытое Акционерное Общество "Фарм-Синтез"	Способ получения нонапептидэтиламида и промежуточные соединения для его получения
KR20160088947A (ko)	2010-06-16	2016-07-26	앙도르쉐르슈 인코포레이티드	에스트로겐-관련 질병의 치료 또는 예방 방법
CA2905131A1 (fr)	2013-03-15	2014-09-18	Durect Corporation	Compositions ayant un agent de modification rheologique pour reduire une variabilite de dissolution
US12274794B2 (en)	2016-07-06	2025-04-15	Orient Pharma Co., Ltd.	Oral dosage form with drug composition, barrier layer and drug layer
CA3167217A1 (fr)	2020-01-13	2021-07-22	Durect Corporation	Systemes d'administration de medicament a liberation prolongee avec impuretes reduites et procedes associes
CN116940358A (zh)	2021-01-12	2023-10-24	度勒科特公司	持续释放药物递送系统和有关的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5726506B2 (fr) *	1974-03-08	1982-06-04
US3914412A (en) *	1973-10-11	1975-10-21	Abbott Lab	{8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity
US3901872A (en) *	1974-03-13	1975-08-26	American Home Prod	P-glu-his-trp-ser-tyr-d-pgl-leu-arg-pro-gly-nh' 2 'and intermediates
US3896104A (en) *	1974-05-22	1975-07-22	American Home Prod	P-glu-his-trp-ser-tyr-d-lys-leu-arg-pro-gly-nh' 2 'and intermediates

1974
- 1974-08-09 DE DE2438350A patent/DE2438350C3/de not_active Expired
1975
- 1975-08-04 NL NLAANVRAGE7509260,A patent/NL182051C/xx not_active IP Right Cessation
- 1975-08-05 IL IL47880A patent/IL47880A/xx unknown
- 1975-08-06 CH CH1028175A patent/CH613186A5/xx not_active IP Right Cessation
- 1975-08-07 CA CA233,179A patent/CA1069888A/fr not_active Expired
- 1975-08-07 US US05/602,910 patent/US4024248A/en not_active Expired - Lifetime
- 1975-08-07 LU LU73166A patent/LU73166A1/xx unknown
- 1975-08-07 SE SE7508926A patent/SE424184B/xx not_active IP Right Cessation
- 1975-08-08 IE IE1771/75A patent/IE41510B1/en unknown
- 1975-08-08 AT AT0618975A patent/AT364093B/de not_active IP Right Cessation
- 1975-08-08 DK DK361875A patent/DK148905C/da not_active IP Right Cessation
- 1975-08-09 JP JP50096316A patent/JPS5761268B2/ja not_active Expired
- 1975-08-11 BE BE159095A patent/BE832310A/fr not_active IP Right Cessation
- 1975-08-11 FR FR7524951A patent/FR2281132A1/fr active Granted
1976
- 1976-08-11 GB GB33426/75A patent/GB1523623A/en not_active Expired
1978
- 1978-05-16 SE SE7805545A patent/SE7805545L/sv unknown

Also Published As

Publication number	Publication date
JPS5148659A (fr)	1976-04-26
IL47880A0 (en)	1975-11-25
IE41510L (en)	1976-02-09
IE41510B1 (en)	1980-01-16
FR2281132A1 (fr)	1976-03-05
DE2438350C3 (de)	1979-06-13
FR2281132B1 (fr)	1979-09-14
DK148905B (da)	1985-11-11
DE2438350B2 (de)	1978-10-26
ATA618975A (de)	1981-02-15
NL182051B (nl)	1987-08-03
DK361875A (da)	1976-02-10
GB1523623A (en)	1978-09-06
AT364093B (de)	1981-09-25
AU8374475A (en)	1977-02-10
BE832310A (fr)	1976-02-11
SE424184B (sv)	1982-07-05
SE7805545L (fr)	1978-05-16
JPS5761268B2 (fr)	1982-12-23
IL47880A (en)	1978-10-31
CH613186A5 (fr)	1979-09-14
SE7508926L (sv)	1976-02-10
NL7509260A (nl)	1976-02-11
CA1069888A (fr)	1980-01-15
DE2438350A1 (de)	1976-02-26
NL182051C (nl)	1988-01-04
LU73166A1 (fr)	1977-04-13
US4024248A (en)	1977-05-17

Legal Events

Date	Code	Title	Description
1995-09-18	PUP	Patent expired

Publication	Publication Date	Title
DK283175A (da)	1975-12-25	Fremgangsmade til fremstilling af benzocycloamid-derivater
DK239075A (da)	1975-12-01	Fremgangsmade til fremstilling af iodbenzenderivater
DK144160C (da)	1982-06-07	Analogifremgangsmaade til fremstilling af 8-thiomethylergoliner
DK144298C (da)	1982-07-12	Fremgangsmaade til fremstilling af alkyl-tert-butylethere
DK385475A (da)	1976-03-14	Fremgangsmade til fremstilling af secoprostaglandiner
DK143801C (da)	1982-03-22	Analogifremgangsmaade til fremstilling af dihydrolysergsyrederivater
DK143902C (da)	1982-04-13	Analogifremgangsmaade til fremstilling af 8alfa-ergolin-i-derivater
DK386175A (da)	1976-02-29	Fremgangsmade til fremstilling af ringsubstituerede pyrazinoisoquinolinderivater
DK140985C (da)	1980-06-02	Analogifremgangsmaade til fremstilling af indolderivater
DK141849C (da)	1980-11-10	Fremgangsmaade til fremstilling af slagseje vinylaromat-podecopolymere
DK142455C (da)	1981-08-03	Analogifremgangsmaade til fremstilling af thiaprostaglandiner
DK538175A (da)	1976-05-29	Fremgangsmade til fremstilling af benzophenonderivater
DK211075A (da)	1975-11-18	Fremgangsmade til fremstilling af abietamidderivater
DK145696C (da)	1983-07-18	Fremgangsmaade til fremstilling af 2-arylamino-2-imidazolin-derivater
DK376975A (da)	1976-02-29	Fremgangsmade til fremstilling af abietamidderivater
DK153479C (da)	1988-11-28	Analogifremgangsmaade til fremstilling af 1,4-benzodiazepin-2-on-derivater
DK146718C (da)	1984-05-21	Analogifremgangsmaade til fremstilling af benzobicyklononener
DK552675A (da)	1976-06-08	Fremgangsmade til fremstilling af 2-acyl-4-oxopyrazinoisoquinolinderivater
DK271975A (da)	1975-12-22	Fremgangsmade til fremstilling af acylderivater
DK198175A (da)	1975-11-08	Fremgangsmade til fremstilling af indolkinolizidinderivater
DK137539C (da)	1978-09-04	Fremgangsmaade til fremstilling af 11beta-fluor-4-androsten-3-oner
DK137185C (da)	1978-07-03	Analogifremgangsmaade til fremstilling af tiofenderivater
DK144065C (da)	1982-05-17	Analogifremgangsmaade til fremstilling af thiazolderivater
DK143939C (da)	1982-04-13	Fremgangsmaade til fremstilling af prostaglandin-fbeta-derivater
DK507275A (da)	1976-05-13	Fremgangsmade til fremstilling af aminomethylarylmethylpenicillin-derivater