DK1492404T3 - Nye spinosyndannende polyketidsyntaser - Google Patents
Nye spinosyndannende polyketidsyntaserInfo
- Publication number
- DK1492404T3 DK1492404T3 DK03713546T DK03713546T DK1492404T3 DK 1492404 T3 DK1492404 T3 DK 1492404T3 DK 03713546 T DK03713546 T DK 03713546T DK 03713546 T DK03713546 T DK 03713546T DK 1492404 T3 DK1492404 T3 DK 1492404T3
- Authority
- DK
- Denmark
- Prior art keywords
- forming
- polyketide synthases
- new spin
- spin
- new
- Prior art date
Links
- 108010030975 Polyketide Synthases Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Catching Or Destruction (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35807502P | 2002-02-19 | 2002-02-19 | |
| PCT/US2003/004998 WO2003070908A2 (en) | 2002-02-19 | 2003-02-19 | Novel spinosyn-producing polyketide synthases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1492404T3 true DK1492404T3 (da) | 2012-04-23 |
Family
ID=27757699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03713546T DK1492404T3 (da) | 2002-02-19 | 2003-02-19 | Nye spinosyndannende polyketidsyntaser |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US20030225006A1 (da) |
| EP (1) | EP1492404B1 (da) |
| JP (1) | JP4765032B2 (da) |
| KR (1) | KR101016561B1 (da) |
| CN (1) | CN1633237B (da) |
| AU (2) | AU2003217591B2 (da) |
| DK (1) | DK1492404T3 (da) |
| ES (1) | ES2375714T3 (da) |
| IL (3) | IL163529A0 (da) |
| MX (1) | MXPA04008071A (da) |
| WO (1) | WO2003070908A2 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL163529A0 (en) | 2002-02-19 | 2005-12-18 | Dow Agrosciences Llc | Novel spinosyn-producing polyketidesynthases |
| GB0327720D0 (en) | 2003-11-28 | 2003-12-31 | Biotica Tech Ltd | Erythromycins and process for their preparation |
| GB0417852D0 (en) | 2004-08-11 | 2004-09-15 | Biotica Tech Ltd | Production of polyketides and other natural products |
| WO2007144786A2 (en) * | 2006-05-26 | 2007-12-21 | Entarco Sa | The vapor-phase application of spinosyn for the control of pests, and formulations and products utilizing the same |
| CN102202506B (zh) * | 2008-09-22 | 2015-07-29 | 克里斯廷·克里蒂考 | 刺糖多孢菌素防污组合物、其使用方法、以及受到保护而免于附着污损生物的制品 |
| AU2010213749B2 (en) * | 2009-02-11 | 2015-01-22 | Dow Agrosciences Llc | Pesticidal compositions |
| JP5619868B2 (ja) * | 2009-04-03 | 2014-11-05 | ダウ アグロサイエンシーズエルエルシー | 水性エマルションを解乳化および分離するための解乳化組成物、系および方法 |
| US8268975B2 (en) | 2009-04-03 | 2012-09-18 | Dow Agrosciences Llc | Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions |
| CA2764526A1 (en) | 2009-06-24 | 2010-12-29 | Christine Kritikou | The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer |
| EP2272963A1 (en) | 2009-07-09 | 2011-01-12 | LEK Pharmaceuticals d.d. | Process for Preparation of Tacrolimus |
| RU2580015C2 (ru) | 2010-05-11 | 2016-04-10 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Штаммы spnk |
| CN101942425B (zh) * | 2010-08-24 | 2012-06-20 | 北京农学院 | 与苯亚甲基丙酮合成相关的酶及其编码基因与应用 |
| EP2654757A1 (en) | 2010-12-22 | 2013-10-30 | Entarco SA | The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents |
| US9404107B2 (en) | 2011-05-03 | 2016-08-02 | Dow Agrosciences Llc | Integration of genes into the chromosome of Saccharopolyspora spinosa |
| DK2520653T3 (da) | 2011-05-03 | 2017-07-03 | Dow Agrosciences Llc | Integration af gener i kromosomet af saccharopolyspora spinosa |
| US9631195B2 (en) | 2011-12-28 | 2017-04-25 | Dow Agrosciences Llc | Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa |
| JP6641366B2 (ja) * | 2014-11-14 | 2020-02-05 | 浙江海正薬業股▲ふん▼有限公司Zhejiang Hisun Pharmaceutical CO.,LTD. | スピノサド異種発現株およびその構築方法ならびに使用 |
| JP2018532708A (ja) | 2015-09-03 | 2018-11-08 | アグリメティス,エルエルシー | 殺虫剤としてのスピノシン誘導体 |
| WO2018226893A2 (en) | 2017-06-06 | 2018-12-13 | Zymergen Inc. | A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa |
| AU2021256845A1 (en) * | 2020-04-14 | 2022-11-24 | Eidgenössische Technische Hochschule Zürich | Cell classifier circuits and methods of use thereof |
| CN116240191B (zh) * | 2023-03-23 | 2026-03-27 | 上海交通大学 | 一种泰乐菌素聚酮合酶酰基转移酶突变体及其应用 |
| CN116334021B (zh) * | 2023-03-30 | 2026-02-03 | 上海交通大学 | 一种多杀菌素酰基转移酶突变体及其应用 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1117005A (en) | 1978-03-07 | 1982-01-26 | Patrick G. Feakins | Animal ear-tags, their manufacture and their use |
| OA09249A (fr) | 1988-12-19 | 1992-06-30 | Lilly Co Eli | Composés de macrolides. |
| US5362634A (en) * | 1989-10-30 | 1994-11-08 | Dowelanco | Process for producing A83543 compounds |
| US5824513A (en) * | 1991-01-17 | 1998-10-20 | Abbott Laboratories | Recombinant DNA method for producing erythromycin analogs |
| WO1993013663A1 (en) | 1992-01-17 | 1993-07-22 | Abbott Laboratories | Method of directing biosynthesis of specific polyketides |
| CN1073483A (zh) * | 1991-11-08 | 1993-06-23 | 道伊兰科公司 | 一种发酵杀虫剂化合物及其制备方法 |
| US5539089A (en) * | 1991-11-08 | 1996-07-23 | Dowelanco | A83543 aglycones and pseudoglycones |
| US5591606A (en) * | 1992-11-06 | 1997-01-07 | Dowelanco | Process for the production of A83543 compounds with Saccharopolyspora spinosa |
| WO1994020518A1 (en) | 1993-03-12 | 1994-09-15 | Dowelanco | New a83543 compounds and process for production thereof |
| CA2197524A1 (en) * | 1996-02-22 | 1997-08-22 | Bradley Stuart Dehoff | Polyketide synthase genes |
| US6001981A (en) | 1996-06-13 | 1999-12-14 | Dow Agrosciences Llc | Synthetic modification of Spinosyn compounds |
| ES2244001T3 (es) * | 1996-07-05 | 2005-12-01 | Biotica Technology Limited | Eritromicinas y procedimiento para su preparacion. |
| JP3441899B2 (ja) | 1996-11-01 | 2003-09-02 | 理化学研究所 | 完全長cDNAライブラリーの作成方法 |
| CO5060464A1 (es) | 1997-12-23 | 2001-07-30 | Novartis Ag | Metodos para controlar plagas con una composicion plaguicida que comprende un compuesto macrolido |
| US6143526A (en) * | 1998-03-09 | 2000-11-07 | Baltz; Richard H. | Biosynthetic genes for spinosyn insecticide production |
| DE19823397B4 (de) | 1998-05-26 | 2011-07-28 | Bayer CropScience AG, 40789 | Verwendung von Spinosynen zum Einsatz als Bodeninsektizide |
| GB9814006D0 (en) * | 1998-06-29 | 1998-08-26 | Biotica Tech Ltd | Polyketides and their synthesis |
| ID29130A (id) | 1998-07-02 | 2001-08-02 | Lilly Co Eli | Formulasi pengendali kutu pada manusia |
| GB9814622D0 (en) * | 1998-07-06 | 1998-09-02 | Biotica Tech Ltd | Polyketides,their preparation,and materials for use therein |
| MXPA01003376A (es) * | 1998-10-02 | 2002-11-07 | Kosan Biosciences Inc | Enzimas policetido sintetasa y construcciones de acido desoxirribonucleico recombinante para las mismas. |
| DE19857966A1 (de) | 1998-12-16 | 2000-06-21 | Bayer Ag | Wirkstoffkombinationen |
| DE19857967A1 (de) | 1998-12-16 | 2000-06-21 | Bayer Ag | Wirkstoffkombinationen |
| CA2361040A1 (en) * | 1999-01-27 | 2000-08-03 | Kosan Biosciences, Inc. | Synthesis of oligoketides |
| JP2000245457A (ja) * | 1999-02-24 | 2000-09-12 | Kitasato Inst:The | エバーメクチンアグリコン合成酵素遺伝子 |
| DE19913174A1 (de) | 1999-03-24 | 2000-09-28 | Bayer Ag | Synergistische insektizide Mischungen |
| GB9912563D0 (en) * | 1999-05-28 | 1999-07-28 | Biotica Tech Ltd | Polyketides and their synthesis |
| US7285653B1 (en) * | 1999-08-27 | 2007-10-23 | Bayer Aktiengesellschaft | Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis |
| ATE280176T1 (de) * | 1999-09-13 | 2004-11-15 | Dow Agrosciences Llc | Pestizide makrolide |
| WO2002007705A1 (en) * | 2000-07-20 | 2002-01-31 | Campina B.V. | Carrier material for dry powder inhalation |
| GB0019986D0 (en) * | 2000-08-14 | 2000-10-04 | Biotica Tech Ltd | Polyketides and their synthesis |
| TWI275592B (en) * | 2001-03-21 | 2007-03-11 | Dow Agrosciences Llc | Synthetic derivatives of 21-butenyl and related spinosyns |
| US6919464B1 (en) * | 2001-03-21 | 2005-07-19 | Dow Agrosciences Llc | Synthetic derivatives of 21-butenyl and related spinosyns |
| DE10135550A1 (de) * | 2001-07-20 | 2003-01-30 | Bayer Cropscience Ag | Verfahren zum Herstellen von neuen Spinosyn-Derivaten |
| IL163529A0 (en) * | 2002-02-19 | 2005-12-18 | Dow Agrosciences Llc | Novel spinosyn-producing polyketidesynthases |
| WO2005109887A1 (en) * | 2004-04-23 | 2005-11-17 | Smart Metric, Inc. | Smartcard with visual display |
-
2003
- 2003-02-19 IL IL16352903A patent/IL163529A0/xx unknown
- 2003-02-19 AU AU2003217591A patent/AU2003217591B2/en not_active Expired
- 2003-02-19 CN CN038041626A patent/CN1633237B/zh not_active Expired - Lifetime
- 2003-02-19 EP EP20030713546 patent/EP1492404B1/en not_active Expired - Lifetime
- 2003-02-19 MX MXPA04008071A patent/MXPA04008071A/es active IP Right Grant
- 2003-02-19 WO PCT/US2003/004998 patent/WO2003070908A2/en not_active Ceased
- 2003-02-19 US US10/368,770 patent/US20030225006A1/en not_active Abandoned
- 2003-02-19 DK DK03713546T patent/DK1492404T3/da active
- 2003-02-19 JP JP2003569801A patent/JP4765032B2/ja not_active Expired - Lifetime
- 2003-02-19 KR KR1020047012851A patent/KR101016561B1/ko not_active Expired - Lifetime
- 2003-02-19 ES ES03713546T patent/ES2375714T3/es not_active Expired - Lifetime
-
2004
- 2004-08-12 IL IL16352904A patent/IL163529A/en active IP Right Grant
-
2005
- 2005-10-20 US US11/254,686 patent/US7626010B2/en not_active Expired - Lifetime
-
2009
- 2009-02-20 AU AU2009200685A patent/AU2009200685B2/en not_active Expired
- 2009-08-18 IL IL200471A patent/IL200471A/en active IP Right Grant
- 2009-11-11 US US12/616,470 patent/US20100068785A1/en not_active Abandoned
-
2011
- 2011-03-28 US US13/073,226 patent/US8624009B2/en not_active Expired - Fee Related
-
2013
- 2013-11-18 US US14/082,494 patent/US9137992B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1633237B (zh) | 2010-05-26 |
| EP1492404B1 (en) | 2011-12-28 |
| AU2003217591B2 (en) | 2009-02-26 |
| CN1633237A (zh) | 2005-06-29 |
| IL163529A0 (en) | 2005-12-18 |
| US7626010B2 (en) | 2009-12-01 |
| US20030225006A1 (en) | 2003-12-04 |
| JP2005520500A (ja) | 2005-07-14 |
| IL200471A (en) | 2015-09-24 |
| WO2003070908A3 (en) | 2004-10-28 |
| US8624009B2 (en) | 2014-01-07 |
| US20060040877A1 (en) | 2006-02-23 |
| ES2375714T3 (es) | 2012-03-05 |
| WO2003070908A2 (en) | 2003-08-28 |
| JP4765032B2 (ja) | 2011-09-07 |
| MXPA04008071A (es) | 2004-11-26 |
| US20100068785A1 (en) | 2010-03-18 |
| EP1492404A2 (en) | 2005-01-05 |
| KR20040085201A (ko) | 2004-10-07 |
| IL163529A (en) | 2011-11-30 |
| EP1492404A4 (en) | 2010-03-17 |
| US20110178036A1 (en) | 2011-07-21 |
| US9137992B2 (en) | 2015-09-22 |
| AU2003217591A1 (en) | 2003-09-09 |
| AU2009200685B2 (en) | 2012-01-12 |
| US20140080777A1 (en) | 2014-03-20 |
| IL200471A0 (en) | 2011-07-31 |
| KR101016561B1 (ko) | 2011-02-22 |
| AU2009200685A1 (en) | 2009-03-12 |
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