DK1495769T3 - Mannose-6-phosphat-receptormedieret gentransfer til muskelceller - Google Patents
Mannose-6-phosphat-receptormedieret gentransfer til muskelcellerInfo
- Publication number
- DK1495769T3 DK1495769T3 DK03077205T DK03077205T DK1495769T3 DK 1495769 T3 DK1495769 T3 DK 1495769T3 DK 03077205 T DK03077205 T DK 03077205T DK 03077205 T DK03077205 T DK 03077205T DK 1495769 T3 DK1495769 T3 DK 1495769T3
- Authority
- DK
- Denmark
- Prior art keywords
- mannose
- muscle cells
- phosphate receptor
- gene transfer
- mediated gene
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03077205A EP1495769B1 (en) | 2003-07-11 | 2003-07-11 | Mannose-6-phosphate receptor mediated gene transfer into muscle cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1495769T3 true DK1495769T3 (da) | 2008-06-23 |
Family
ID=33442814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03077205T DK1495769T3 (da) | 2003-07-11 | 2003-07-11 | Mannose-6-phosphat-receptormedieret gentransfer til muskelceller |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1495769B1 (da) |
| AT (1) | ATE387217T1 (da) |
| DE (1) | DE60319354T2 (da) |
| DK (1) | DK1495769T3 (da) |
| ES (1) | ES2302898T3 (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1766010T3 (pl) | 2004-06-28 | 2011-07-29 | Univ Western Australia | Antysensowne oligonukleotydy do indukcji pominięcia egzonu i sposoby ich zastosowania |
| GB0524987D0 (en) | 2005-12-08 | 2006-01-18 | Ge Healthcare Ltd | Novel imaging agents for fibrosis |
| WO2007123391A1 (en) | 2006-04-20 | 2007-11-01 | Academisch Ziekenhuis Leiden | Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene. |
| EP1857548A1 (en) | 2006-05-19 | 2007-11-21 | Academisch Ziekenhuis Leiden | Means and method for inducing exon-skipping |
| JP6047270B2 (ja) | 2006-08-11 | 2016-12-21 | バイオマリン テクノロジーズ ベー．フェー． | Ｄｎａリピートの不安定性に関連した遺伝的障害を治療するための方法及び手段 |
| CA2693742A1 (en) | 2007-07-12 | 2009-01-15 | Prosensa Technologies B.V. | Molecules for targeting compounds to various selected organs, tissues or tumor cells |
| CN103212085A (zh) | 2007-07-12 | 2013-07-24 | 普罗森那技术公司 | 用于使化合物靶向多种选定器官或组织的分子 |
| EP2203173B1 (en) | 2007-10-26 | 2015-12-23 | Academisch Ziekenhuis Leiden | Means and methods for counteracting muscle disorders |
| USRE48468E1 (en) | 2007-10-26 | 2021-03-16 | Biomarin Technologies B.V. | Means and methods for counteracting muscle disorders |
| WO2009099326A1 (en) | 2008-02-08 | 2009-08-13 | Prosensa Holding Bv | Methods and means for treating dna repeat instability associated genetic disorders |
| EP2119783A1 (en) | 2008-05-14 | 2009-11-18 | Prosensa Technologies B.V. | Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means |
| CN105779453A (zh) | 2008-10-24 | 2016-07-20 | 萨雷普塔治疗公司 | 用于dmd的多外显子跳跃组合物 |
| EP2421971B1 (en) | 2009-04-24 | 2016-07-06 | BioMarin Technologies B.V. | Oligonucleotide comprising an inosine for treating dmd |
| WO2011000958A1 (en) * | 2009-07-03 | 2011-01-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compounds targeting the cation-independent mannose 6-phosphate receptor |
| BR122023023194A2 (pt) | 2009-11-12 | 2023-12-26 | The University Of Western Australia | Oligonucleotídeo antissentido, composição e respectivo uso |
| EP2516647B1 (en) | 2009-12-24 | 2016-12-14 | BioMarin Technologies B.V. | Molecule for treating an inflammatory disorder |
| CN118581086A (zh) | 2012-01-27 | 2024-09-03 | 比奥马林技术公司 | 用于治疗杜兴型肌营养不良症和贝克型肌营养不良症的具有改善特性的rna调节性寡核苷酸 |
| AU2013336237A1 (en) | 2012-10-22 | 2015-06-11 | Sabag-Rfa Ltd | A system for delivering therapeutic agents into living cells and cells nuclei |
| SG10201804331TA (en) | 2012-11-15 | 2018-07-30 | Roche Innovation Ct Copenhagen As | Oligonucleotide conjugates |
| US20150368642A1 (en) | 2013-01-30 | 2015-12-24 | Hoffmann-La Roche Inc. | Lna oligonucleotide carbohydrate conjugates |
| WO2014118272A1 (en) | 2013-01-30 | 2014-08-07 | Santaris Pharma A/S | Antimir-122 oligonucleotide carbohydrate conjugates |
| EA202090946A3 (ru) | 2013-03-14 | 2021-07-30 | Сарепта Терапьютикс, Инк. | Композиции, обеспечивающие пропускание экзонов, для лечения мышечной дистрофии |
| NZ631289A (en) | 2013-03-15 | 2017-08-25 | Sarepta Therapeutics Inc | Improved compositions for treating muscular dystrophy |
| AU2014300981B2 (en) | 2013-06-27 | 2017-08-10 | Ricc A/S | Antisense oligomers and conjugates targeting PCSK9 |
| GB201408623D0 (en) | 2014-05-15 | 2014-07-02 | Santaris Pharma As | Oligomers and oligomer conjugates |
| TWI794662B (zh) | 2016-03-14 | 2023-03-01 | 瑞士商赫孚孟拉羅股份公司 | 用於降低pd-l1表現之寡核苷酸 |
| JP7503072B2 (ja) | 2019-02-26 | 2024-06-19 | ロシュ イノベーション センター コペンハーゲン エーエス | オリゴヌクレオチドの製剤化方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6172208B1 (en) * | 1992-07-06 | 2001-01-09 | Genzyme Corporation | Oligonucleotides modified with conjugate groups |
-
2003
- 2003-07-11 DE DE60319354T patent/DE60319354T2/de not_active Expired - Lifetime
- 2003-07-11 EP EP03077205A patent/EP1495769B1/en not_active Expired - Lifetime
- 2003-07-11 ES ES03077205T patent/ES2302898T3/es not_active Expired - Lifetime
- 2003-07-11 AT AT03077205T patent/ATE387217T1/de not_active IP Right Cessation
- 2003-07-11 DK DK03077205T patent/DK1495769T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| DE60319354D1 (de) | 2008-04-10 |
| ES2302898T3 (es) | 2008-08-01 |
| DE60319354T2 (de) | 2009-03-26 |
| EP1495769B1 (en) | 2008-02-27 |
| ATE387217T1 (de) | 2008-03-15 |
| EP1495769A1 (en) | 2005-01-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE387217T1 (de) | Mannose-6-phosphat rezeptor vermittelter gentransfer zu muskelzellen | |
| EP2487258A3 (en) | MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers | |
| EP2500430A3 (en) | Antisense oligonucleotides for inducing exon skipping and methods of use thereof | |
| SI1670828T1 (sl) | Kompletna humana protitelesa protu humanem 4-1bb (cd137) | |
| EP2596803A3 (en) | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates | |
| HUP0202635A3 (en) | Targeting multimeric imaging agents through multilocus binding | |
| EA201070030A1 (ru) | Синтез и применение антиинвертированных фосфоротиоатных аналогов кэп-структуры матричной phk | |
| MX2009004510A (es) | Oligorribonucleotidos y sus usos. | |
| EP2567964A3 (en) | Monomer Compositions for the Synthesis of RNA, Methods of Synthesis, and Methods of Deprotection | |
| WO2008078190A3 (en) | Compounds for fluorescence imaging | |
| MXPA04000210A (es) | Conjugados quelantes mejorados. | |
| IL150061A0 (en) | Purine derivatives | |
| AU7597498A (en) | Novel sulfur transfer reagents for oligonucleotide synthesis | |
| WO2004096996A3 (en) | Modulation of glucagon receptor expression | |
| WO2007072061A3 (en) | Crystalline pyrimidine nucleoside derivatives suspensions in capsules | |
| IL179303A0 (en) | Preparation of macromolecular conjugates by four-component condensation reaction | |
| BRPI0414107B8 (pt) | produtos intermediários para a preparação de híbridos de oxazolidinon-quinolona | |
| Kiviniemi et al. | Synthesis of aminoglycoside-3′-conjugates of 2′-O-methyl oligoribonucleotides and their invasion to a 19F labeled HIV-1 TAR model | |
| AU2002217893A1 (en) | Universal supports for oligonucleotide synthesis | |
| ATE374212T1 (de) | Neue kalium-kanäle und dafür kodierende gene | |
| AU2003224917A8 (en) | Diabetes imaging probes | |
| Kadam et al. | Degradation of phorate by Azotobacter isolates | |
| IL174804A0 (en) | Retroviral vectors for delivery of interfering rna | |
| JP2003508618A5 (da) | ||
| WO2004065620A3 (en) | Modulation of thyroid hormone receptor interactor 3 expression |