DK1513529T3 - Tredobbelte monoamin-genoptagelsesinhibitorer til behandling af kronisk smerte - Google Patents

Tredobbelte monoamin-genoptagelsesinhibitorer til behandling af kronisk smerte

Info

Publication number: DK1513529T3
Authority: DK; Denmark
Prior art keywords: treatment; chronic pain; monoamin; term; recovery inhibitors
Prior art date: 2002-05-30

Application number

DK03724899.4T

Other languages

English (en)

Inventor

Gordon J Blackburn-Munro

Jorgen Scheel-Krueger

Original Assignee

Neurosearch As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-30

Filing date

2003-05-27

Publication date

2012-03-26

2003-05-27 Application filed by Neurosearch As filed Critical Neurosearch As

2012-03-26 Application granted granted Critical

2012-03-26 Publication of DK1513529T3 publication Critical patent/DK1513529T3/da

Links

208000000094 Chronic Pain Diseases 0.000 title abstract 2
208000002193 Pain Diseases 0.000 title abstract 2
239000003112 inhibitor Substances 0.000 title 1
238000011084 recovery Methods 0.000 title 1
239000003174 triple reuptake inhibitor Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Nutrition Science (AREA)
Psychiatry (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK03724899.4T 2002-05-30 2003-05-27 Tredobbelte monoamin-genoptagelsesinhibitorer til behandling af kronisk smerte DK1513529T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA200200832		2002-05-30
PCT/DK2003/000352 WO2003101453A1 (en)	2002-05-30	2003-05-27	Triple monoamine reuptake inhibitors for the treatment of chronic pain

Publications (1)

Publication Number	Publication Date
DK1513529T3 true DK1513529T3 (da)	2012-03-26

Family

ID=29594978

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03724899.4T DK1513529T3 (da)	2002-05-30	2003-05-27	Tredobbelte monoamin-genoptagelsesinhibitorer til behandling af kronisk smerte

Country Status (11)

Country	Link
US (1)	US7459464B2 (da)
EP (1)	EP1513529B1 (da)
JP (1)	JP2005531594A (da)
CN (2)	CN1655787A (da)
AT (1)	ATE536874T1 (da)
AU (1)	AU2003227520B9 (da)
CA (1)	CA2484482C (da)
DK (1)	DK1513529T3 (da)
MX (1)	MXPA04011859A (da)
NZ (1)	NZ536415A (da)
WO (1)	WO2003101453A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA06005545A (es) *	2003-11-18	2006-08-17	Boehringer Ingelheim Int	Preparacion farmaceutica solida.
KR101594898B1 (ko)	2005-07-15	2016-02-18	알바니 몰레큘라 리써치, 인크.	아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
EP1779851A1 (en) *	2005-10-31	2007-05-02	Boehringer Ingelheim Pharma GmbH & Co.KG	Treatment of diabetes
GB0703998D0 (en) *	2007-03-01	2007-04-11	Glaxo Group Ltd	Novel salt
US8802696B2 (en)	2009-05-12	2014-08-12	Albany Molecular Research, Inc.	7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoqu inoli and use thereof
WO2010132487A1 (en)	2009-05-12	2010-11-18	Bristol-Myers Squibb Company	CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
WO2012024397A2 (en)	2010-08-17	2012-02-23	Albany Molecular Research, Inc.	2,5-methano-and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5936675A (ja) *	1982-07-13	1984-02-28	サンド・アクチエンゲゼルシヤフト	二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
CA2163095A1 (en) *	1993-05-18	1994-11-24	Huw M. L. Davies	Treatment process with biologically active tropane derivatives
BR9707636A (pt) *	1996-02-22	1999-07-27	Neurosearch As	Composto composição farmacêutica uso de um composto e processos para preparar composto e para tratar um distúrbio ou doença de um organismo animal vivo
GB9617990D0 (en) *	1996-08-29	1996-10-09	Scotia Holdings Plc	Treatment of pain
US6331571B1 (en) *	1998-08-24	2001-12-18	Sepracor, Inc.	Methods of treating and preventing attention deficit disorders
US6323242B1 (en)	1998-12-02	2001-11-27	Peter Sterling Mueller	Treatment of disorders secondary to organic impairments
US6803387B1 (en) *	1999-03-19	2004-10-12	Abbott Gmbh & Co. Kg	Treatment of neuropathic pain or fibromyalgia
ES2246488T3 (es) *	1999-07-01	2006-02-16	PHARMACIA & UPJOHN COMPANY LLC	Reboxetina para tratar la migraña.
JP2005508872A (ja) *	2001-05-23	2005-04-07	ニューロサーチ、アクティーゼルスカブ	トロパン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害剤として使用する方法
WO2002094827A1 (en) *	2001-05-23	2002-11-28	Neurosearch A/S	Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

2003
- 2003-05-27 EP EP03724899A patent/EP1513529B1/en not_active Expired - Lifetime
- 2003-05-27 CN CNA038123762A patent/CN1655787A/zh active Pending
- 2003-05-27 WO PCT/DK2003/000352 patent/WO2003101453A1/en not_active Ceased
- 2003-05-27 JP JP2004508810A patent/JP2005531594A/ja active Pending
- 2003-05-27 CN CNA2008101763724A patent/CN101444509A/zh active Pending
- 2003-05-27 NZ NZ536415A patent/NZ536415A/en not_active IP Right Cessation
- 2003-05-27 AU AU2003227520A patent/AU2003227520B9/en not_active Ceased
- 2003-05-27 MX MXPA04011859A patent/MXPA04011859A/es active IP Right Grant
- 2003-05-27 AT AT03724899T patent/ATE536874T1/de active
- 2003-05-27 DK DK03724899.4T patent/DK1513529T3/da active
- 2003-05-27 US US10/515,275 patent/US7459464B2/en not_active Expired - Fee Related
- 2003-05-27 CA CA2484482A patent/CA2484482C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO2003101453A1 (en)	2003-12-11
EP1513529B1 (en)	2011-12-14
AU2003227520A1 (en)	2003-12-19
EP1513529A1 (en)	2005-03-16
US20050239824A1 (en)	2005-10-27
MXPA04011859A (es)	2005-03-31
AU2003227520B2 (en)	2008-05-01
CN1655787A (zh)	2005-08-17
CA2484482C (en)	2011-07-26
AU2003227520B9 (en)	2008-06-26
NZ536415A (en)	2006-10-27
CA2484482A1 (en)	2003-12-11
CN101444509A (zh)	2009-06-03
ATE536874T1 (de)	2011-12-15
JP2005531594A (ja)	2005-10-20
US7459464B2 (en)	2008-12-02

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