NO20090596L - Antivirale fosfinatforbindelser - Google Patents

Antivirale fosfinatforbindelser

Info

Publication number
NO20090596L
NO20090596L NO20090596A NO20090596A NO20090596L NO 20090596 L NO20090596 L NO 20090596L NO 20090596 A NO20090596 A NO 20090596A NO 20090596 A NO20090596 A NO 20090596A NO 20090596 L NO20090596 L NO 20090596L
Authority
NO
Norway
Prior art keywords
compounds
phosphinate compounds
antiviral
antiviral phosphinate
methods
Prior art date
Application number
NO20090596A
Other languages
English (en)
Inventor
Aesop Cho
Choung U Kim
Maria Fardis
Jianying Wang
Anthony Casarez
Kleem Chaudhary
Michael Clarke
Edward Doerffler
Hyungjung Pyun
Xiaoning C Sheng
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of NO20090596L publication Critical patent/NO20090596L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Oppfinnelsen vedrører antivirale fosfinatforbindelser, preparater som inneholder slike forbindelser, og terapeutiske fremgangsmåter som omfatter administreringen av slike forbindelser, samt fremgangsmåter og mellomprodukter som kan anvendes til fremstilling av slike forbindelser.
NO20090596A 2006-07-07 2009-02-06 Antivirale fosfinatforbindelser NO20090596L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81948806P 2006-07-07 2006-07-07
US83290806P 2006-07-24 2006-07-24
PCT/US2007/015664 WO2008005565A2 (en) 2006-07-07 2007-07-06 Antiviral phosphinate compounds

Publications (1)

Publication Number Publication Date
NO20090596L true NO20090596L (no) 2009-04-01

Family

ID=38626760

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090596A NO20090596L (no) 2006-07-07 2009-02-06 Antivirale fosfinatforbindelser

Country Status (19)

Country Link
US (4) US20090227491A1 (no)
EP (2) EP2422791B1 (no)
JP (3) JP2009542698A (no)
KR (1) KR20090026216A (no)
CN (1) CN102532198A (no)
AR (1) AR061840A1 (no)
AT (1) ATE554776T1 (no)
AU (1) AU2007269567B2 (no)
BR (1) BRPI0713961A2 (no)
CA (1) CA2656356C (no)
EA (1) EA018098B1 (no)
ES (2) ES2531315T3 (no)
HR (1) HRP20090076A2 (no)
IL (1) IL195489A0 (no)
MX (1) MX2009000236A (no)
NO (1) NO20090596L (no)
TW (1) TW200819460A (no)
WO (1) WO2008005565A2 (no)
ZA (1) ZA200810400B (no)

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RU2008152171A (ru) * 2006-07-05 2010-08-10 Интермьюн, Инк. (Us) Новые ингибиторы вирусной репликации гепатита с
KR20090026216A (ko) 2006-07-07 2009-03-11 길리애드 사이언시즈, 인코포레이티드 항바이러스 포스피네이트 화합물
MX2010011306A (es) * 2008-04-15 2010-11-09 Intermune Inc Nuevos inhibidores macrociclicos de la replicacion del virus de la hepatitis c.
WO2010101967A2 (en) * 2009-03-04 2010-09-10 Idenix Pharmaceuticals, Inc. Phosphothiophene and phosphothiazole hcv polymerase inhibitors
TW201111381A (en) * 2009-06-23 2011-04-01 Gilead Sciences Inc Pharmaceutical combinations useful for treating HCV
US8476225B2 (en) 2009-12-04 2013-07-02 Gilead Sciences, Inc. Antiviral compounds
US20110306541A1 (en) * 2010-06-10 2011-12-15 Gilead Sciences, Inc. Methods for treating hcv
WO2012087596A1 (en) * 2010-12-20 2012-06-28 Gilead Sciences, Inc. Combinations for treating hcv
US8957203B2 (en) 2011-05-05 2015-02-17 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US8691757B2 (en) 2011-06-15 2014-04-08 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
AU2012308295B2 (en) 2011-09-16 2017-10-26 Gilead Sciences, Inc. Methods for treating HCV
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
SE1450130A1 (sv) 2011-10-21 2014-05-07 Abbvie Inc Förfaranden för att behandla hcv innefattande minst två direktverkande antivirala agenser, ribavirin men inte interferon
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
EP2583680A3 (en) 2011-10-21 2013-06-12 Abbvie Inc. Mono (PSI-7977) or combination treatment of DAAs for use in treating HCV
BR112015007879A2 (pt) 2012-10-19 2017-07-04 Bristol Myers Squibb Co inibidores do vírus da hepatite c
US9643999B2 (en) 2012-11-02 2017-05-09 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
EP2914613B1 (en) 2012-11-02 2017-11-22 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
US9334279B2 (en) 2012-11-02 2016-05-10 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US9409943B2 (en) 2012-11-05 2016-08-09 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
MY172166A (en) 2013-01-31 2019-11-15 Gilead Pharmasset Llc Combination formulation of two antiviral compounds
EP2964664B1 (en) 2013-03-07 2017-01-11 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
CN103539831B (zh) * 2013-09-29 2016-02-03 北京林业大学 山杏α-葡萄糖苷酶抑制肽及其制备方法和用途
CN103539833B (zh) * 2013-09-29 2016-02-03 北京林业大学 高活性α-葡萄糖苷酶抑制肽及其制备方法和用途
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения
ES2969239T3 (es) 2016-05-27 2024-05-17 Gilead Sciences Inc Combinación de ledipasvir y sofosbuvir para su uso en el tratamiento de infecciones por el virus de la hepatitis B en humanos

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US4816570A (en) * 1982-11-30 1989-03-28 The Board Of Regents Of The University Of Texas System Biologically reversible phosphate and phosphonate protective groups
US4968788A (en) * 1986-04-04 1990-11-06 Board Of Regents, The University Of Texas System Biologically reversible phosphate and phosphonate protective gruops
EP0533833B1 (en) 1990-06-13 1995-12-20 GLAZIER, Arnold Phosphorous produgs
DE69129650T2 (de) 1990-09-14 1999-03-25 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic, Prag/Praha Wirkstoffvorläufer von Phosphonaten
DE4308096A1 (de) 1993-03-13 1994-09-15 Hoechst Ag Prodrug-Derivate von Enzyminhibitoren mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung
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DE19843360A1 (de) * 1998-09-22 2000-03-30 Hassan Jomaa Phosphororganische Verbindungen und ihre Verwendung
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KR101294467B1 (ko) 2005-07-25 2013-09-09 인터뮨, 인크. Ｃ형 간염 바이러스 복제의 신규 거대고리형 억제제
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Also Published As

Publication number Publication date
HK1127295A1 (en) 2009-09-25
US8674088B2 (en) 2014-03-18
US7893264B2 (en) 2011-02-22
JP2012107061A (ja) 2012-06-07
JP6010640B2 (ja) 2016-10-19
EP2422791B1 (en) 2014-12-17
US20090227491A1 (en) 2009-09-10
WO2008005565A2 (en) 2008-01-10
ES2531315T3 (es) 2015-03-12
WO2008005565A9 (en) 2009-01-29
US20080057031A1 (en) 2008-03-06
ATE554776T1 (de) 2012-05-15
CN102532198A (zh) 2012-07-04
EA200900154A1 (ru) 2009-06-30
BRPI0713961A2 (pt) 2012-11-27
US20110081314A1 (en) 2011-04-07
JP2015083605A (ja) 2015-04-30
AR061840A1 (es) 2008-09-24
EP2043658B1 (en) 2012-04-25
IL195489A0 (en) 2009-09-01
EP2422791A1 (en) 2012-02-29
MX2009000236A (es) 2009-01-23
EP2043658A2 (en) 2009-04-08
TW200819460A (en) 2008-05-01
US20110082112A1 (en) 2011-04-07
AU2007269567B2 (en) 2012-11-08
EA018098B1 (ru) 2013-05-30
KR20090026216A (ko) 2009-03-11
CA2656356A1 (en) 2008-01-10
CA2656356C (en) 2013-04-09
JP2009542698A (ja) 2009-12-03
HRP20090076A2 (hr) 2009-05-31
ZA200810400B (en) 2011-12-28
AU2007269567A1 (en) 2008-01-10
US8586744B2 (en) 2013-11-19
WO2008005565A3 (en) 2008-05-02
ES2388969T3 (es) 2012-10-22

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FC2A Withdrawal, rejection or dismissal of laid open patent application