DK1526870T3 - Kombination af loteprednol-etabonat OFHO til behandling af respiratoriske sygdomme, allergiske sygdomme, astma og COPD - Google Patents

Kombination af loteprednol-etabonat OFHO til behandling af respiratoriske sygdomme, allergiske sygdomme, astma og COPD

Info

Publication number: DK1526870T3
Authority: DK; Denmark
Prior art keywords: copd; asthma; treatment; loteprednol; allergic
Prior art date: 2002-08-09

Application number

DK03790851T

Other languages

English (en)

Inventor

Mathias Locher

Robert Hermann

Original Assignee

Meda Pharma Gmbh & Co Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-09

Filing date

2003-08-04

Publication date

2007-09-10

2003-08-04 Application filed by Meda Pharma Gmbh & Co Kg filed Critical Meda Pharma Gmbh & Co Kg

2007-09-10 Application granted granted Critical

2007-09-10 Publication of DK1526870T3 publication Critical patent/DK1526870T3/da

Links

208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 title abstract 3
208000006673 asthma Diseases 0.000 title abstract 2
230000000172 allergic effect Effects 0.000 title 1
208000010668 atopic eczema Diseases 0.000 title 1
230000000241 respiratory effect Effects 0.000 title 1
229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 abstract 2
239000002587 phosphodiesterase IV inhibitor Substances 0.000 abstract 2
201000009961 allergic asthma Diseases 0.000 abstract 1
208000026935 allergic disease Diseases 0.000 abstract 1
239000003862 glucocorticoid Substances 0.000 abstract 1
YPZVAYHNBBHPTO-MXRBDKCISA-N loteprednol Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)OCCl)[C@@H]4[C@@H]3CCC2=C1 YPZVAYHNBBHPTO-MXRBDKCISA-N 0.000 abstract 1
229960001798 loteprednol Drugs 0.000 abstract 1
DPHDSIQHVGSITN-UHFFFAOYSA-N n-(3,5-dichloropyridin-4-yl)-2-[1-[(4-fluorophenyl)methyl]-5-hydroxyindol-3-yl]-2-oxoacetamide Chemical compound C1=C(C(=O)C(=O)NC=2C(=CN=CC=2Cl)Cl)C2=CC(O)=CC=C2N1CC1=CC=C(F)C=C1 DPHDSIQHVGSITN-UHFFFAOYSA-N 0.000 abstract 1
208000023504 respiratory system disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Pulmonology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK03790851T 2002-08-09 2003-08-04 Kombination af loteprednol-etabonat OFHO til behandling af respiratoriske sygdomme, allergiske sygdomme, astma og COPD DK1526870T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10236688		2002-08-09
PCT/EP2003/008607 WO2004019984A1 (de)	2002-08-09	2003-08-04	Neue kombination von glucocorticoiden und pde-4-inhibitoren zur behandlung von atemwegserkrankungen, allergischen erkrankungen, asthma und copd

Publications (1)

Publication Number	Publication Date
DK1526870T3 true DK1526870T3 (da)	2007-09-10

Family

ID=31968961

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03790851T DK1526870T3 (da)	2002-08-09	2003-08-04	Kombination af loteprednol-etabonat OFHO til behandling af respiratoriske sygdomme, allergiske sygdomme, astma og COPD

Country Status (18)

Country	Link
US (1)	US20050288265A1 (da)
EP (1)	EP1526870B1 (da)
JP (1)	JP2005539042A (da)
CN (1)	CN1308038C (da)
AT (1)	ATE361076T1 (da)
AU (1)	AU2003255365B2 (da)
CA (1)	CA2492645A1 (da)
CY (1)	CY1107696T1 (da)
DE (1)	DE50307184D1 (da)
DK (1)	DK1526870T3 (da)
EA (1)	EA008981B1 (da)
ES (1)	ES2285238T3 (da)
HR (1)	HRP20050224B1 (da)
MX (1)	MXPA05001573A (da)
NO (1)	NO20051212D0 (da)
PT (1)	PT1526870E (da)
UA (1)	UA82323C2 (da)
WO (1)	WO2004019984A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10241407A1 (de) *	2002-09-06	2004-03-18	Elbion Ag	Behandlung nicht allergischer Rhinitis durch selektive Phosphodiesterase 4-Hemmstoffe
WO2005074982A2 (en) *	2004-02-06	2005-08-18	Meda Pharma Gmbh & Co. Kg	Combination of anticholinergics and inhibitors of phosphodiesterase type 4 for the treatment of respiratory diseases
EP1713473B1 (en)	2004-02-06	2013-03-13	MEDA Pharma GmbH & Co. KG	The combination of anticholinergics and glucocorticoids for the long-term treatment of asthma and copd
ES2570332T3 (es)	2005-03-16	2016-05-17	Meda Pharma Gmbh & Co Kg	La combinación de anticolinérgicos y antagonistas del receptor de leucotrieno para el tratamiento de enfermedades respiratorias
US8506934B2 (en)	2005-04-29	2013-08-13	Robert I. Henkin	Methods for detection of biological substances
NZ591969A (en)	2005-12-21	2012-05-25	Meda Pharma Gmbh & Co Kg	Combination of anticholinergics, glucocorticoids, beta2-adrenoceptor agonists, PDE 4 inhibitor and antileukotriene for the treatment of inflammatory diseases
CA2644889A1 (en) *	2006-03-07	2007-09-13	Combinatorx, Incorporated	Compositions and methods for the treatment of immunoinflammatory disorders
US8293489B2 (en)	2007-01-31	2012-10-23	Henkin Robert I	Methods for detection of biological substances
US8580801B2 (en)	2008-07-23	2013-11-12	Robert I. Henkin	Phosphodiesterase inhibitor treatment
CN102309756A (zh) *	2010-07-02	2012-01-11	天津金耀集团有限公司	含有磷酸二酯酶4抑制剂和糖皮质激素的治疗皮肤病的复方药物
US10864219B2 (en)	2012-05-03	2020-12-15	The Johns Hopkins University	Compositions and methods for ophthalmic and/or other applications
US11596599B2 (en)	2012-05-03	2023-03-07	The Johns Hopkins University	Compositions and methods for ophthalmic and/or other applications
KR102310775B1 (ko)	2012-05-03	2021-10-07	칼라 파마슈티컬스, 인크.	개선된 점막 수송을 나타내는 제약 나노입자
US9827191B2 (en)	2012-05-03	2017-11-28	The Johns Hopkins University	Compositions and methods for ophthalmic and/or other applications
AU2013256064B2 (en) *	2012-05-03	2018-01-04	Alcon Inc.	Pharmaceutical nanoparticles showing improved mucosal transport
EP2968204B1 (en) *	2013-03-15	2019-05-15	Robert I. Henkin	Phosphodiesterase inhibitors for treating taste and smell disorders
US10598672B2 (en)	2014-02-18	2020-03-24	Cyrano Therapeutics, Inc.	Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
JP7606530B2 (ja)	2020-03-24	2024-12-25	シラノセラピューティクス，インコーポレイテッド	コロナウイルス感染症による化学感覚機能障害の治療

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE449106B (sv) *	1980-07-10	1987-04-06	Otsuka Pharma Co Ltd	Steroid med anti-inflammatorisk verkan samt komposition innehallande denna
US4996335A (en) *	1980-07-10	1991-02-26	Nicholas S. Bodor	Soft steroids having anti-inflammatory activity
AU718967B2 (en) *	1997-02-05	2000-05-04	Jagotec Ag	Medical aerosol formulations
TR200003130T2 (tr) *	1998-04-28	2001-01-22	Arzneimittelwerk Dresden Gmbh	Yeni hidroksiindoller, bunların fosfodiesteraz 4 inhibitörleri olarak kullanımları ve hazırlanmaları için işlemler
DE19917504A1 (de) *	1999-04-17	2000-10-19	Dresden Arzneimittel	Verwendung von Hydroxyindolen, die Inhibitoren der Phosphodiesterase 4 sind, zur Therapie chronisch obstruktiver Lungenerkrankungen
DE19947234A1 (de) *	1999-09-30	2001-04-05	Asta Medica Ag	Neue Kombination von Loteprednol und Antihistaminika
US20040214805A1 (en) *	1999-11-02	2004-10-28	Smithkline Beecham Corporation	Method and compositions for treating pulmonary diseases
AR029189A1 (es) *	1999-11-02	2003-06-18	Smithkline Beecham Corp	Uso de un inhibidor de fosfodiesterasa 4 y un corticoesteroide antiinflamatorio en forma combinada, separadamente o separadamente secuencial para la preparacion de un medicamento
DK1289945T3 (da) *	2000-05-19	2004-11-01	Alcon Inc	Anilindisulfidderivater til behandling af allergiske sygdomme
GB0123951D0 (en) *	2001-10-05	2001-11-28	Glaxo Group Ltd	Therapies for treating respiratory diseases
HUP0401747A3 (en) *	2001-11-05	2005-06-28	Merck Patent Gmbh	Piridazine derivatives of hydrazono-malonitriles, their use, process for preparation of the compounds and pharmaceutical compositions containing the compounds
US20030092706A1 (en) *	2001-11-09	2003-05-15	Johannes Barsig	Combination

2003
- 2003-04-08 UA UAA200500512A patent/UA82323C2/uk unknown
- 2003-08-04 WO PCT/EP2003/008607 patent/WO2004019984A1/de not_active Ceased
- 2003-08-04 EA EA200500328A patent/EA008981B1/ru not_active IP Right Cessation
- 2003-08-04 AT AT03790851T patent/ATE361076T1/de not_active IP Right Cessation
- 2003-08-04 MX MXPA05001573A patent/MXPA05001573A/es active IP Right Grant
- 2003-08-04 DK DK03790851T patent/DK1526870T3/da active
- 2003-08-04 EP EP03790851A patent/EP1526870B1/de not_active Expired - Lifetime
- 2003-08-04 DE DE50307184T patent/DE50307184D1/de not_active Expired - Lifetime
- 2003-08-04 JP JP2004531853A patent/JP2005539042A/ja active Pending
- 2003-08-04 CA CA002492645A patent/CA2492645A1/en not_active Abandoned
- 2003-08-04 PT PT03790851T patent/PT1526870E/pt unknown
- 2003-08-04 AU AU2003255365A patent/AU2003255365B2/en not_active Ceased
- 2003-08-04 HR HR20050224A patent/HRP20050224B1/xx not_active IP Right Cessation
- 2003-08-04 US US10/523,802 patent/US20050288265A1/en not_active Abandoned
- 2003-08-04 ES ES03790851T patent/ES2285238T3/es not_active Expired - Lifetime
- 2003-08-04 CN CNB038190575A patent/CN1308038C/zh not_active Expired - Fee Related
2005
- 2005-03-08 NO NO20051212A patent/NO20051212D0/no not_active Application Discontinuation
2007
- 2007-07-12 CY CY20071100927T patent/CY1107696T1/el unknown

Also Published As

Publication number	Publication date
EA008981B1 (ru)	2007-10-26
ES2285238T3 (es)	2007-11-16
ATE361076T1 (de)	2007-05-15
CA2492645A1 (en)	2004-03-11
NO20051212L (no)	2005-03-08
HRP20050224A2 (en)	2005-04-30
MXPA05001573A (es)	2005-04-25
EP1526870A1 (de)	2005-05-04
JP2005539042A (ja)	2005-12-22
EP1526870B1 (de)	2007-05-02
DE50307184D1 (de)	2007-06-14
CN1674939A (zh)	2005-09-28
HK1078463A1 (en)	2006-03-17
CN1308038C (zh)	2007-04-04
NO20051212D0 (no)	2005-03-08
HRP20050224B1 (hr)	2007-12-31
UA82323C2 (uk)	2008-04-10
CY1107696T1 (el)	2013-04-18
AU2003255365A1 (en)	2004-03-19
US20050288265A1 (en)	2005-12-29
PT1526870E (pt)	2007-07-09
WO2004019984A1 (de)	2004-03-11
EA200500328A1 (ru)	2005-06-30
AU2003255365B2 (en)	2009-02-19

Publication	Publication Date	Title
CY1107696T1 (el)	2013-04-18	Συνδιασμος εταβονικης λοτεπρεδνολης και dfho για την αντιμετωπιση αναπνευστικων παθησεων, αλλεργικων παθησεων, ασθματος και copd
MXPA02011311A (es)	2003-04-25	Composicion novedosa.
SE0200356D0 (sv)	2002-02-05	Novel use
ATE508735T1 (de)	2011-05-15	Pulmonale verabreichung von aminoglykosiden
NO20052591L (no)	2005-07-29	Pyridopyrolizin og pyridoindolizinderivater
DK1718336T3 (da)	2008-10-20	Ny kombination af anticholinergikum og beta-mimetika til behandling af luftvejssygdomme
NO20025220L (no)	2002-10-31	Ny fremgangsmåte
WO2005041864A3 (en)	2006-05-18	Combination of cyclooxygenase-2 inhibitor and phosphodiesterase 4 inhibitor and method
DK1478438T3 (da)	2012-08-27	Fremgangsmåder og sammensætninger til behandling af astma
WO2005086915A3 (en)	2006-03-23	Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor
IS7898A (is)	2005-06-20	Ný samverkandi samsetning sem felur í sér róflúmílast og formóteról
MXPA04007294A (es)	2004-10-29	Composicion para inhalacion.
IS7899A (is)	2005-06-20	Samverkandi samsetning sem felur í sér róflúmílast og (R.R)-formóteról
GB0218573D0 (en)	2002-09-18	Treatment of chronic obstructive pulmonary disease (COPD) and other disorders