DK152883D0 - Fremgangsmade til fremstilling af k- eller 6-substituerede ethyleniske benzimidazoler - Google Patents

Fremgangsmade til fremstilling af k- eller 6-substituerede ethyleniske benzimidazoler

Info

Publication number
DK152883D0
DK152883D0 DK1528/83A DK152883A DK152883D0 DK 152883 D0 DK152883 D0 DK 152883D0 DK 1528/83 A DK1528/83 A DK 1528/83A DK 152883 A DK152883 A DK 152883A DK 152883 D0 DK152883 D0 DK 152883D0
Authority
DK
Denmark
Prior art keywords
benzimidazoles
procedure
preparation
substituted ethylenic
ethylenic
Prior art date
Application number
DK1528/83A
Other languages
English (en)
Other versions
DK152883A (da
Inventor
Tina Marie Morwick
Jr Charles Johnson Paget
James Howard Wikel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK152883D0 publication Critical patent/DK152883D0/da
Publication of DK152883A publication Critical patent/DK152883A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK152883A 1982-04-08 1983-04-06 Fremgangsmaade til fremstilling af 5- eller 6-substituerede ethyleniske benzimidazoler DK152883A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/366,760 US4420479A (en) 1982-04-08 1982-04-08 Olefinic benzimidazoles, formulations, and antiviral methods

Publications (2)

Publication Number Publication Date
DK152883D0 true DK152883D0 (da) 1983-04-06
DK152883A DK152883A (da) 1983-10-09

Family

ID=23444387

Family Applications (1)

Application Number Title Priority Date Filing Date
DK152883A DK152883A (da) 1982-04-08 1983-04-06 Fremgangsmaade til fremstilling af 5- eller 6-substituerede ethyleniske benzimidazoler

Country Status (18)

Country Link
US (1) US4420479A (da)
EP (1) EP0091795A1 (da)
KR (1) KR840004409A (da)
AU (1) AU1322483A (da)
CA (1) CA1197245A (da)
DD (1) DD209624A5 (da)
DK (1) DK152883A (da)
ES (2) ES521318A0 (da)
FI (1) FI831191A7 (da)
GB (1) GB2119789B (da)
GR (1) GR78168B (da)
IL (1) IL68299A0 (da)
NZ (1) NZ203798A (da)
PH (1) PH18108A (da)
PL (3) PL247909A1 (da)
PT (1) PT76499B (da)
RO (1) RO86319B (da)
ZA (1) ZA832410B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69214467T3 (de) * 1991-01-10 2000-09-28 Transcend Therapeutics, Inc. Verwendung von L-2-oxo Thiazolidin-4-carboxylat zur Behandlung von Atemnotsyndrom
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
JP2787539B2 (ja) * 1993-02-26 1998-08-20 松森  昭 ウイルス性疾患の予防または治療剤
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
US5475109A (en) * 1994-10-17 1995-12-12 Merck & Co., Inc. Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease
US5693661A (en) * 1995-06-07 1997-12-02 Eli Lilly And Company Anti-viral compounds
US5545653A (en) * 1995-06-07 1996-08-13 Eli Lilly And Company Anti-viral compounds
US5891874A (en) * 1996-06-05 1999-04-06 Eli Lilly And Company Anti-viral compound
JP2000511899A (ja) * 1996-06-05 2000-09-12 イーライ・リリー・アンド・カンパニー 抗―ウイルス性化合物群
US5821242A (en) * 1996-06-06 1998-10-13 Eli Lilly And Company Anti-viral compounds
JP4214537B2 (ja) 1996-08-12 2009-01-28 セルジーン コーポレーション 新規な免疫治療薬とこの薬物を使用してサイトカインレベルを抵減する方法
AU6031898A (en) * 1997-01-22 1998-08-07 Eli Lilly And Company Anti-viral compounds
AU7715198A (en) * 1997-06-04 1998-12-21 Eli Lilly And Company Anti-viral compounds
US7470723B2 (en) 2003-03-05 2008-12-30 Celgene Corporation Diphenylethylene compounds and uses thereof
BRPI0408005A (pt) 2003-03-05 2006-02-14 Celgene Corp composto, composição farmacêutica, métodos para inibir angiogênese, atividade de pde4 em uma célula e proliferação de célula de cáncer, para inibir ou reduzir polimerização de tubulina ou estabilidade de tubulina em uma célula, para tratar ou melhorar um distúrbio inflamatório, um cáncer e um distúrbio do sistema nervoso central e para visar, bloquear ou destruir a função de vasculatura de tumor e o endotélio de vasos de tumor
EP1794139A2 (en) 2004-09-03 2007-06-13 Celgene Corporation Substituted heterocyclic compounds and uses thereof
CN108997158B (zh) * 2018-07-16 2020-12-15 青岛科技大学 一种实现二取代酰胺与二苯基甲酮偶联的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018790A (en) * 1975-05-08 1977-04-19 Eli Lilly And Company Substituted 1-sulfonylbenzimidazoles
PT65486B (en) * 1975-08-28 1978-03-24 Lilly Co Eli Process for the preparation of carbonil-substituted 1-sulfonylbenzimidazoles
US4174454A (en) * 1975-08-28 1979-11-13 Eli Lilly And Company Alkylidenylmethyl-substituted 1-sulfonylbenzimidazoles
CA1076582A (en) * 1975-10-28 1980-04-29 Charles J. Paget Antiviral thiazolinyl or thiazinyl ketobenzimidazoles
US4008243A (en) * 1975-11-19 1977-02-15 Eli Lilly And Company Antiviral thiazolinyl or thiazinyl benzimidazole esters
US4118573A (en) * 1975-11-24 1978-10-03 Eli Lilly And Company Substituted 1-sulfonylbenzimidazoles
GR66420B (da) * 1976-12-15 1981-03-20 Lilly Co Eli
US4230868A (en) * 1979-04-17 1980-10-28 Eli Lilly And Company α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles
US4316021A (en) * 1979-08-13 1982-02-16 Eli Lilly And Company Substituted 1-sulfonylbenzimidazoles

Also Published As

Publication number Publication date
FI831191L (fi) 1983-10-09
DD209624A5 (de) 1984-05-16
RO86319A (ro) 1985-03-15
FI831191A0 (fi) 1983-04-08
RO86319B (ro) 1985-03-31
PL241385A1 (en) 1984-09-24
EP0091795A1 (en) 1983-10-19
GB2119789B (en) 1985-08-29
ES8505966A1 (es) 1985-06-01
DK152883A (da) 1983-10-09
US4420479A (en) 1983-12-13
PL247909A1 (en) 1984-12-17
CA1197245A (en) 1985-11-26
ZA832410B (en) 1984-11-28
ES8502097A1 (es) 1984-12-16
PT76499A (en) 1983-05-01
KR840004409A (ko) 1984-10-15
GB2119789A (en) 1983-11-23
PL247908A1 (en) 1985-01-16
AU1322483A (en) 1983-10-13
ES534218A0 (es) 1985-06-01
ES521318A0 (es) 1984-12-16
IL68299A0 (en) 1983-07-31
FI831191A7 (fi) 1983-10-09
GR78168B (da) 1984-09-26
NZ203798A (en) 1985-07-12
PT76499B (en) 1986-03-18
PH18108A (en) 1985-03-22

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
PBP Patent lapsed