DK153290A - Polypeptid, vaccine indeholdende dette og ekspressionssystem indeholdende en dna-sekvens, der kan udtrykke polypeptidet - Google Patents

Polypeptid, vaccine indeholdende dette og ekspressionssystem indeholdende en dna-sekvens, der kan udtrykke polypeptidet Download PDF

Info

Publication number
DK153290A
DK153290A DK153290A DK153290A DK153290A DK 153290 A DK153290 A DK 153290A DK 153290 A DK153290 A DK 153290A DK 153290 A DK153290 A DK 153290A DK 153290 A DK153290 A DK 153290A
Authority
DK
Denmark
Prior art keywords
polypeptide
glycoproteins
express
dna sequence
expression system
Prior art date
Application number
DK153290A
Other languages
English (en)
Other versions
DK153290D0 (da
DK173175B1 (da
Inventor
Michael Wathen
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DK153290D0 publication Critical patent/DK153290D0/da
Publication of DK153290A publication Critical patent/DK153290A/da
Application granted granted Critical
Publication of DK173175B1 publication Critical patent/DK173175B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK199001532A 1987-12-23 1990-06-22 Polypeptid indeholdende fragmenter fra de to human respiratorisk syncytial virus-glycoproteiner F og G, vaccine indeholdende dette og ekspressionssystem indeholdende en DNA-sekvens, der kan udtrykke polypeptidet DK173175B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13738787A 1987-12-23 1987-12-23
US13738787 1987-12-23
PCT/US1988/003784 WO1989005823A1 (en) 1987-12-23 1988-10-31 Chimeric glycoproteins containing immunogenic segments of the glycoproteins of human respiratory syncytial virus
US8803784 1988-10-31

Publications (3)

Publication Number Publication Date
DK153290D0 DK153290D0 (da) 1990-06-22
DK153290A true DK153290A (da) 1990-08-16
DK173175B1 DK173175B1 (da) 2000-03-06

Family

ID=22477194

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199001532A DK173175B1 (da) 1987-12-23 1990-06-22 Polypeptid indeholdende fragmenter fra de to human respiratorisk syncytial virus-glycoproteiner F og G, vaccine indeholdende dette og ekspressionssystem indeholdende en DNA-sekvens, der kan udtrykke polypeptidet

Country Status (14)

Country Link
US (2) US5194595A (da)
EP (1) EP0396563B1 (da)
JP (1) JP2716503B2 (da)
KR (1) KR0137963B1 (da)
AT (1) ATE85622T1 (da)
AU (1) AU617739B2 (da)
CA (1) CA1320163C (da)
DE (1) DE3878468T2 (da)
DK (1) DK173175B1 (da)
FI (1) FI102382B (da)
HK (1) HK166295A (da)
MX (1) MX9203458A (da)
NO (1) NO300254B1 (da)
WO (1) WO1989005823A1 (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8914968D0 (en) * 1989-06-29 1989-08-23 Connaught Lab Production of virus and purification of viral envelope proteins for vaccine use
US6004563A (en) * 1990-11-07 1999-12-21 American Home Products Corporation Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
US5824307A (en) * 1991-12-23 1998-10-20 Medimmune, Inc. Human-murine chimeric antibodies against respiratory syncytial virus
GB9200117D0 (en) 1992-01-06 1992-02-26 Connaught Lab Production of recombinant chimeric proteins for vaccine use
GB9207479D0 (en) * 1992-04-06 1992-05-20 Scotgen Ltd Novel antibodies for treatment and prevention of respiratory syncytial virus infection in animals and man
TW275632B (da) * 1992-04-21 1996-05-11 American Cyanamid Co
WO1994015968A1 (en) * 1993-01-08 1994-07-21 The Upjohn Company Process for the purification and refolding of human respiratory syncytial virus fg glycoprotein
ATE196737T1 (de) * 1993-05-25 2000-10-15 American Cyanamid Co Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus
US7300918B2 (en) 1994-01-14 2007-11-27 Matthias Rath Method of producing vaccines from protein signal oligopeptides
DE69534077T2 (de) * 1994-01-14 2005-08-11 Rath, Matthias, Dr.med. Verwendung von methoden zur identifizierung von hydrophilen signal-oligopeptiden
FR2718452B1 (fr) 1994-04-06 1996-06-28 Pf Medicament Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
US5716821A (en) * 1994-09-30 1998-02-10 Uab Research Foundation Prevention and treatment of respiratory tract disease
WO1996010400A1 (en) * 1994-09-30 1996-04-11 The Uab Research Foundation Gene therapy vectors and vaccines based on non-segmented negatives stranded rna viruses
FR2726472B1 (fr) 1994-11-07 1997-01-31 Pf Medicament Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin
DE4442114A1 (de) * 1994-11-25 1996-05-30 Buna Sow Leuna Olefinverb Gmbh Nitrit-, phosphat- und aminfreies Kühl- und Wärmeübertragungsmittel
US5811524A (en) * 1995-06-07 1998-09-22 Idec Pharmaceuticals Corporation Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
US6015664A (en) * 1995-11-03 2000-01-18 Mcw Research Foundation Multiplex PCR assay using unequal primer concentrations to detect HPIV 1,2,3 and RSV A,B and influenza virus A, B
WO1998018819A1 (en) * 1996-10-29 1998-05-07 Smithkline Beecham Biologicals S.A. Purification of respiratory syncytial virus antigens
US20070067859A1 (en) * 1997-07-14 2007-03-22 Michel Georges Double-muscling in mammals
US6103466A (en) * 1997-07-14 2000-08-15 University Of Liege Double-muscling in mammals
PT2045322E (pt) 1997-07-14 2015-10-16 Université de Liège Musculatura dupla em mamíferos
US6699478B1 (en) * 1997-09-19 2004-03-02 Wyeth Holdings Corporation Enhanced immune response to attachment (G) protein of Respiratory Syncytial Virus
GB9909077D0 (en) 1999-04-20 1999-06-16 Smithkline Beecham Biolog Novel compositions
CA2398466A1 (en) * 2000-01-27 2001-08-02 Medimmune, Inc. Ultra high affinity neutralizing antibodies
AU4002001A (en) 2000-03-01 2001-09-12 Med Immune Inc High potency recombinant antibodies and method for producing them
US6855493B2 (en) 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7179900B2 (en) * 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7132100B2 (en) 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
CN100508953C (zh) * 2004-05-24 2009-07-08 波利门科学生物免疫研究有限公司 用于药物释放的过载脂质体
US20060115485A1 (en) * 2004-10-29 2006-06-01 Medimmune, Inc. Methods of preventing and treating RSV infections and related conditions
EP1997830A1 (en) * 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV specific binding molecules and means for producing them
KR101617895B1 (ko) 2007-12-24 2016-05-03 글락소스미스클라인 바이오로지칼즈 에스.에이. 재조합 ｒｓｖ 항원
US20110177117A1 (en) * 2008-07-18 2011-07-21 Normand Blais Chimeric respiratory syncytial virus polypeptide antigens
DK2445526T3 (da) 2009-06-24 2016-06-27 Glaxosmithkline Biologicals Sa Rekombinante RSV-antigener.
TW201116294A (en) 2009-07-15 2011-05-16 Novartis Ag RSV F protein compositions and methods for making same
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
CN103842374A (zh) 2011-05-13 2014-06-04 诺华股份有限公司 融合前的rsv f抗原
EA201891945A3 (ru) 2012-08-01 2019-05-31 Бавариан Нордик А/С Вакцина рекомбинантного модифицированного вируса осповакцины анкара (mva) респираторно-синцитиального вируса (rsv)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855224A (en) * 1984-03-09 1989-08-08 Genentech, Inc. Molecularly cloned diagnostic product and method of use
WO1987004185A1 (en) * 1986-01-14 1987-07-16 University Of North Carolina Vaccines for human respiratory virus
US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
US5001230A (en) * 1988-02-18 1991-03-19 Schering Corporation T cell activation markers
SG106639A1 (en) * 2000-10-10 2004-10-29 Gen Electric Apparatus and method for introducing small amounts of refractory elements into a vapor deposition coating

Also Published As

Publication number Publication date
FI102382B1 (fi) 1998-11-30
KR0137963B1 (ko) 1998-04-30
EP0396563B1 (en) 1993-02-10
JP2716503B2 (ja) 1998-02-18
AU617739B2 (en) 1991-12-05
US5288630A (en) 1994-02-22
EP0396563A1 (en) 1990-11-14
DK153290D0 (da) 1990-06-22
ATE85622T1 (de) 1993-02-15
FI102382B (fi) 1998-11-30
CA1320163C (en) 1993-07-13
HK166295A (en) 1995-11-03
DE3878468D1 (de) 1993-03-25
AU2785089A (en) 1989-07-19
NO902802D0 (no) 1990-06-22
FI903154A0 (fi) 1990-06-21
DK173175B1 (da) 2000-03-06
DE3878468T2 (de) 1993-06-09
MX9203458A (es) 1992-09-01
NO300254B1 (no) 1997-05-05
NO902802L (no) 1990-06-22
WO1989005823A1 (en) 1989-06-29
KR900700508A (ko) 1990-08-13
US5194595A (en) 1993-03-16
JPH03501723A (ja) 1991-04-18

Similar Documents

Publication Publication Date Title
DK153290D0 (da) Polypeptid, vaccine indeholdende dette og ekspressionssystem indeholdende en dna-sekvens, der kan udtrykke polypeptidet
DK251890D0 (da) Polypeptid og dets anvendelse samt ekspressionssystem til dets eksprimering
DK79190D0 (da) Praktisk taget rent polypeptid og dets anvendelse; rekombinantvirus, rekombinantvirus, rekomninant-dna-vektor og encellet organisme til dets fremstilling
ES8203226A1 (es) Procedimiento de preparar complejos vacunantes por reaccion de arn ribonosales y de antigenos especificos.
EE9900343A (et) Sünteetiline polünukleotiid, immuunvastuste tekitamise meetod, immunogeenne kompositsioon, anti-HIV immuunvastuste indutseerimise meetod, meetod antigeeni tekitava raku indutseerimiseks ja farmatseutiline kompositsioon
CA2231603A1 (en) Chicken interleukin-15 and uses thereof
ES8401134A1 (es) "metodo de producir un cultivo transformante de celulas de vertebrado".
DE3854213D1 (de) Analoge der Untereinheit des von rekombinanter DNS abgeleiteten Bordetella-Toxins.
ES2006925A6 (es) Procedimiento para la preparacion de vectores de expresion.
DE3853139D1 (de) Rekombinanter, fremde gene enthaltender menschlicher cytomegalovirus und seine verwendung.
ATE101200T1 (de) Impfstoffe gegen menschliche respiratorische viren.
EP0236977A3 (en) Bovine virus diarrhea and hog cholera vaccines
MY101874A (en) Vaccine
DK8789A (da) Fremgangsmaade til fremstilling af modificerede, staerkt afsvaekkede rna-virusstammer samt vaccine og dens anvendelse
ZA941853B (en) Stimulation of immune response by viral protein
EP0186368A3 (en) Biological preparations

Legal Events

Date Code Title Description
PUP Patent expired