DK1564205T3 - Fremgangsmåde til fremstilling af (7-methoxy-1-naphthyl)-acetonitril og anvendelse heraf ved syntese af agomelatin - Google Patents

Fremgangsmåde til fremstilling af (7-methoxy-1-naphthyl)-acetonitril og anvendelse heraf ved syntese af agomelatin

Info

Publication number: DK1564205T3
Authority: DK; Denmark
Prior art keywords: agomelatine; naphthyl; acetonitrile; methoxy; synthesis
Prior art date: 2004-02-13

Application number

DK05290310T

Other languages

Danish (da)

English (en)

Inventor

Jean-Claude Souvie

Blanco Isaac Gonzalez

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-13

Filing date

2005-02-11

Publication date

2008-09-29

2005-02-11 Application filed by Servier Lab filed Critical Servier Lab

2008-09-29 Application granted granted Critical

2008-09-29 Publication of DK1564205T3 publication Critical patent/DK1564205T3/da

Links

PYJMGUQHJINLLD-UHFFFAOYSA-N 2-(7-methoxynaphthalen-1-yl)acetonitrile Chemical compound C1=CC=C(CC#N)C2=CC(OC)=CC=C21 PYJMGUQHJINLLD-UHFFFAOYSA-N 0.000 title 1
YJYPHIXNFHFHND-UHFFFAOYSA-N agomelatine Chemical compound C1=CC=C(CCNC(C)=O)C2=CC(OC)=CC=C21 YJYPHIXNFHFHND-UHFFFAOYSA-N 0.000 title 1
229960002629 agomelatine Drugs 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
238000000034 method Methods 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/24—Surgical instruments, devices or methods for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
- A61B17/244—Surgical instruments, devices or methods for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers for cleaning of the tongue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C17/00—Devices for cleaning, polishing, rinsing or drying teeth, teeth cavities or prostheses; Saliva removers; Dental appliances for receiving spittle
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Surgery (AREA)
Animal Behavior & Ethology (AREA)
Dentistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Medical Informatics (AREA)
Heart & Thoracic Surgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Oral & Maxillofacial Surgery (AREA)
Otolaryngology (AREA)
Pulmonology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK05290310T 2004-02-13 2005-02-11 Fremgangsmåde til fremstilling af (7-methoxy-1-naphthyl)-acetonitril og anvendelse heraf ved syntese af agomelatin DK1564205T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0401437A FR2866337B1 (fr)	2004-02-13	2004-02-13	Nouveau procede de synthese du (7-methoxy-1-naphtyl) acetonitrile et application a la synthese de l'aglomelatine

Publications (1)

Publication Number	Publication Date
DK1564205T3 true DK1564205T3 (da)	2008-09-29

Family

ID=34685017

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05290310T DK1564205T3 (da)	2004-02-13	2005-02-11	Fremgangsmåde til fremstilling af (7-methoxy-1-naphthyl)-acetonitril og anvendelse heraf ved syntese af agomelatin

Country Status (32)

Country	Link
US (2)	US7470806B2 (de)
EP (1)	EP1564205B1 (de)
JP (1)	JP4157529B2 (de)
KR (1)	KR100682698B1 (de)
CN (1)	CN1300100C (de)
AR (1)	AR047740A1 (de)
AT (1)	ATE395326T1 (de)
AU (1)	AU2005200615B8 (de)
BR (1)	BRPI0502037B8 (de)
CA (1)	CA2495975A1 (de)
CY (1)	CY1111081T1 (de)
DE (1)	DE602005006634D1 (de)
DK (1)	DK1564205T3 (de)
EA (1)	EA007787B1 (de)
ES (1)	ES2308409T3 (de)
FR (1)	FR2866337B1 (de)
GE (1)	GEP20063929B (de)
HR (1)	HRP20080315T3 (de)
MA (1)	MA27516A1 (de)
ME (1)	ME01403B (de)
MX (1)	MXPA05001636A (de)
MY (1)	MY140089A (de)
NO (1)	NO333493B1 (de)
NZ (1)	NZ538193A (de)
PL (1)	PL1564205T3 (de)
PT (1)	PT1564205E (de)
RS (1)	RS50594B (de)
SG (1)	SG114705A1 (de)
SI (1)	SI1564205T1 (de)
UA (1)	UA79623C2 (de)
WO (1)	WO2005077889A1 (de)
ZA (1)	ZA200501255B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011154140A2 (en)	2010-06-10	2011-12-15	Gador S.A.	New process for the preparation of n-[2-(7-methoxy-1-naphthyl)-ethyl]acetamide and new crystalline form
WO2013054273A2 (en)	2011-10-11	2013-04-18	Ranbaxy Laboratories Limited	Process for the preparation of agomelatine
US20140336380A1 (en)	2011-12-01	2014-11-13	Ranbaxy Laboratories Limited	Process for the preparation of agomelatine
ITMI20121444A1 (it)	2012-08-27	2014-02-28	Procos Spa	Processo per la produzione di agomelatine
FR3014434B1 (fr) *	2013-12-05	2015-12-25	Servier Lab	Nouveau procede de synthese du 7-methoxy-naphtalene-1-carbaldehyde et application a la synthese de l'agomelatine
CN112574066B (zh) *	2019-09-27	2024-10-25	江苏豪森药业集团有限公司	一种阿戈美拉汀中间体的制备方法
CN111377829A (zh) *	2020-04-10	2020-07-07	苏州敬业医药化工有限公司	一种7-甲氧基-1-萘乙腈的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4169108A (en) *	1973-08-16	1979-09-25	Sterling Drug Inc.	5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols
US4327022A (en) *	1973-08-16	1982-04-27	Sterling Drug Inc.	Heterocyclic alkyl naphthols
US3931188A (en) *	1974-05-06	1976-01-06	Bristol-Myers Company	3-Hydroxy-5,6-benzomorphinan derivatives
US3992403A (en) *	1975-05-30	1976-11-16	Schering Corporation	2-Imidazolines and their use as hypoglycemic agents
FR2658818B1 (fr) *	1990-02-27	1993-12-31	Adir Cie	Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

2004
- 2004-02-13 FR FR0401437A patent/FR2866337B1/fr not_active Expired - Fee Related
2005
- 2005-02-01 CA CA002495975A patent/CA2495975A1/fr not_active Abandoned
- 2005-02-04 US US11/051,868 patent/US7470806B2/en active Active
- 2005-02-07 SG SG200500679A patent/SG114705A1/en unknown
- 2005-02-07 MY MYPI20050474A patent/MY140089A/en unknown
- 2005-02-10 MX MXPA05001636A patent/MXPA05001636A/es active IP Right Grant
- 2005-02-11 RS RSP-2008/0349A patent/RS50594B/sr unknown
- 2005-02-11 PL PL05290310T patent/PL1564205T3/pl unknown
- 2005-02-11 AT AT05290310T patent/ATE395326T1/de active
- 2005-02-11 NZ NZ538193A patent/NZ538193A/en not_active IP Right Cessation
- 2005-02-11 EP EP05290310A patent/EP1564205B1/de not_active Expired - Lifetime
- 2005-02-11 GE GEAP8623A patent/GEP20063929B/en unknown
- 2005-02-11 PT PT05290310T patent/PT1564205E/pt unknown
- 2005-02-11 WO PCT/FR2005/000325 patent/WO2005077889A1/fr not_active Ceased
- 2005-02-11 MA MA28099A patent/MA27516A1/fr unknown
- 2005-02-11 DK DK05290310T patent/DK1564205T3/da active
- 2005-02-11 SI SI200530266T patent/SI1564205T1/sl unknown
- 2005-02-11 UA UAA200501280A patent/UA79623C2/uk unknown
- 2005-02-11 ME MEP-2008-959A patent/ME01403B/de unknown
- 2005-02-11 AU AU2005200615A patent/AU2005200615B8/en not_active Expired
- 2005-02-11 BR BRPI0502037A patent/BRPI0502037B8/pt not_active IP Right Cessation
- 2005-02-11 DE DE602005006634T patent/DE602005006634D1/de not_active Expired - Lifetime
- 2005-02-11 AR ARP050100500A patent/AR047740A1/es unknown
- 2005-02-11 ES ES05290310T patent/ES2308409T3/es not_active Expired - Lifetime
- 2005-02-11 NO NO20050739A patent/NO333493B1/no unknown
- 2005-02-11 ZA ZA2005/01255A patent/ZA200501255B/en unknown
- 2005-02-12 KR KR1020050011749A patent/KR100682698B1/ko not_active Expired - Lifetime
- 2005-02-14 EA EA200500204A patent/EA007787B1/ru unknown
- 2005-02-14 JP JP2005035756A patent/JP4157529B2/ja not_active Expired - Lifetime
- 2005-02-16 CN CNB2005100716239A patent/CN1300100C/zh not_active Expired - Lifetime
2008
- 2008-06-10 CY CY20081100616T patent/CY1111081T1/el unknown
- 2008-07-01 HR HR20080315T patent/HRP20080315T3/xx unknown
- 2008-11-26 US US12/313,921 patent/US7994359B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1564205B1 (de)	2008-05-14
CN1300100C (zh)	2007-02-14
ES2308409T3 (es)	2008-12-01
CN1680297A (zh)	2005-10-12
PL1564205T3 (pl)	2008-09-30
BRPI0502037B8 (pt)	2021-05-25
FR2866337A1 (fr)	2005-08-19
MA27516A1 (fr)	2005-09-01
US20090118544A1 (en)	2009-05-07
AR047740A1 (es)	2006-02-15
US20050182270A1 (en)	2005-08-18
JP2005239717A (ja)	2005-09-08
FR2866337B1 (fr)	2006-05-26
NO20050739L (no)	2005-08-15
RS50594B (sr)	2010-05-07
PT1564205E (pt)	2008-06-19
CY1111081T1 (el)	2015-06-11
AU2005200615B8 (en)	2011-05-26
HK1078564A1 (en)	2006-03-17
NO20050739D0 (no)	2005-02-11
CA2495975A1 (fr)	2005-08-13
BRPI0502037B1 (pt)	2018-07-10
NZ538193A (en)	2005-12-23
MXPA05001636A (es)	2005-08-19
BRPI0502037A (pt)	2005-11-16
KR100682698B1 (ko)	2007-02-15
ZA200501255B (en)	2005-11-30
UA79623C2 (en)	2007-07-10
ATE395326T1 (de)	2008-05-15
WO2005077889A1 (fr)	2005-08-25
SG114705A1 (en)	2005-09-28
SI1564205T1 (sl)	2008-08-31
EP1564205A1 (de)	2005-08-17
JP4157529B2 (ja)	2008-10-01
MY140089A (en)	2009-11-30
US7470806B2 (en)	2008-12-30
EA200500204A1 (ru)	2005-08-25
ME01403B (de)	2010-05-07
AU2005200615B2 (en)	2011-05-12
US7994359B2 (en)	2011-08-09
KR20060041903A (ko)	2006-05-12
HRP20080315T3 (en)	2008-07-31
GEP20063929B (en)	2006-09-25
EA007787B1 (ru)	2007-02-27
NO333493B1 (no)	2013-06-24
DE602005006634D1 (de)	2008-06-26
AU2005200615A1 (en)	2005-09-01

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