DK158087D0 - Hidtil ukendte benzothiazinderivater og sammensaetning indeholdende samme - Google Patents

Hidtil ukendte benzothiazinderivater og sammensaetning indeholdende samme

Info

Publication number: DK158087D0
Authority: DK; Denmark
Prior art keywords: hydrogen; pct; composition containing; lower alkyl; containing same
Prior art date: 1985-07-29

Application number

DK158087A

Other languages

English (en)

Other versions

DK158087A (da

Inventor

Jun-Ichi Iwao

Tadashi Iso

Masayuki Oya

Original Assignee

Santen Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-29

Filing date

1987-03-27

Publication date

1987-03-27

1985-07-29 Priority claimed from PCT/JP1985/000426 external-priority patent/WO1987000837A1/ja

1987-03-27 Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd

1987-03-27 Publication of DK158087A publication Critical patent/DK158087A/da

1987-03-27 Publication of DK158087D0 publication Critical patent/DK158087D0/da

Links

UJVBZCCNLAAMOV-UHFFFAOYSA-N 2h-1,2-benzothiazine Chemical class C1=CC=C2C=CNSC2=C1 UJVBZCCNLAAMOV-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 3
125000004423 acyloxy group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000005194 alkoxycarbonyloxy group Chemical group 0.000 abstract 2
125000003282 alkyl amino group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000005236 alkanoylamino group Chemical group 0.000 abstract 1
125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
-1 nitro, hydroxy Chemical group 0.000 abstract 1
229940124597 therapeutic agent Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Sheets, Magazines, And Separation Thereof (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Compositions Of Macromolecular Compounds (AREA)

DK158087A 1985-07-29 1987-03-27 Hidtil ukendte benzothiazinderivater og sammensaetning indeholdende samme DK158087D0 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
PCT/JP1985/000426 WO1987000837A1 (fr)	1985-07-29	1985-07-29	Nouveaux derives de benzothiazine
JP17353185		1985-08-06
PCT/JP1986/000379 WO1987000838A1 (fr)	1985-07-29	1986-07-21	Nouveaux derives de benzothiazine

Publications (2)

Publication Number	Publication Date
DK158087A DK158087A (da)	1987-03-27
DK158087D0 true DK158087D0 (da)	1987-03-27

Family

ID=15962257

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK158087A DK158087D0 (da)	1985-07-29	1987-03-27	Hidtil ukendte benzothiazinderivater og sammensaetning indeholdende samme

Country Status (10)

Country	Link
US (1)	US4786635A (da)
EP (1)	EP0237573B1 (da)
KR (1)	KR890004196B1 (da)
AT (1)	ATE71622T1 (da)
AU (1)	AU587057B2 (da)
DE (1)	DE3683483D1 (da)
DK (1)	DK158087D0 (da)
FI (1)	FI87352C (da)
NO (1)	NO170082C (da)
WO (1)	WO1987000838A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3614363A1 (de) *	1986-04-28	1987-10-29	Hoechst Ag	Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389113B (de) *	1987-10-08	1989-10-25	Hoechst Ag	Neue benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389112B (de) *	1987-10-08	1989-10-25	Hoechst Ag	Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DK0429676T3 (da) *	1989-06-16	1997-03-10	Santen Pharmaceutical Co Ltd
ATE133863T1 (de)	1990-11-29	1996-02-15	Santen Pharmaceutical Co Ltd	Therapeutisches mittel gegen glaukom, das 2- phenyl-3-oxo-2h-1,4-benzothiazinderivate enthält
HUP0101699A3 (en) *	1998-03-31	2002-05-28	Warner Lambert Co	Benzoxazinones/benzothiazinones as serine protease inhibitors and pharmaceutical compositions containing the same
EA200500234A1 (ru)	2002-08-19	2005-08-25	Пфайзер Продактс Инк.	Комбинированная терапия гиперпролиферативных болезней
CA2574958A1 (en) *	2004-07-26	2006-02-09	Cotherix, Inc.	Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
WO2007050783A2 (en)	2005-10-26	2007-05-03	Asahi Kasei Pharma Corporation	Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
EP2351569B1 (en)	2005-10-26	2012-08-22	Asahi Kasei Pharma Corporation	Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
US7919506B2 (en)	2006-03-10	2011-04-05	Pfizer Inc.	Dibenzyl amine compounds and derivatives
ATE547394T1 (de)	2006-12-01	2012-03-15	Bristol Myers Squibb Co	N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
US20090069413A1 (en) *	2007-09-09	2009-03-12	Protia, Llc	Deuterium-enriched olopatadine
WO2012037665A1 (en)	2010-09-24	2012-03-29	Oral Delivery Technology Ltd.	Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
CN105143203A (zh)	2013-04-17	2015-12-09	辉瑞大药厂	用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en)	2014-10-08	2016-04-14	Pfizer Inc.	Substituted amide compounds
WO2020150473A2 (en)	2019-01-18	2020-07-23	Dogma Therapeutics, Inc.	Pcsk9 inhibitors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5651465A (en) *	1979-10-02	1981-05-09	Yoshitomi Pharmaceut Ind Ltd	Benzothiazine derivative
JPS59144775A (ja) *	1983-02-07	1984-08-18	Santen Pharmaceut Co Ltd	ヒドロキシフエニルベンゾチアジン誘導体およびその製造法
JPS59148771A (ja) *	1983-02-09	1984-08-25	Santen Pharmaceut Co Ltd	ベンゾチアジン誘導体
US4584300A (en) *	1983-02-07	1986-04-22	Santen Pharmaceutical Co., Ltd.	Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor
DE3347173A1 (de) *	1983-12-27	1985-07-04	Hoechst Ag, 6230 Frankfurt	Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
JPS60166674A (ja) *	1984-02-09	1985-08-29	Santen Pharmaceut Co Ltd	ベンゾチアジン誘導体
WO1986005490A1 (fr) *	1985-03-19	1986-09-25	Santen Pharmaceutical Co., Ltd.	Derives de 2-arylbenzothiazine
AU4673285A (en) *	1985-07-29	1987-03-05	Santen Pharmaceutical Co. Ltd.	Novel benzothiazine derivatives

1986
- 1986-07-21 AU AU61371/86A patent/AU587057B2/en not_active Ceased
- 1986-07-21 WO PCT/JP1986/000379 patent/WO1987000838A1/ja not_active Ceased
- 1986-07-21 KR KR1019870700275A patent/KR890004196B1/ko not_active Expired
- 1986-07-21 AT AT86904393T patent/ATE71622T1/de not_active IP Right Cessation
- 1986-07-21 US US07/034,164 patent/US4786635A/en not_active Expired - Fee Related
- 1986-07-21 DE DE8686904393T patent/DE3683483D1/de not_active Expired - Lifetime
- 1986-07-21 EP EP86904393A patent/EP0237573B1/en not_active Expired - Lifetime
1987
- 1987-03-26 FI FI871322A patent/FI87352C/fi not_active IP Right Cessation
- 1987-03-27 DK DK158087A patent/DK158087D0/da unknown
- 1987-03-27 NO NO871314A patent/NO170082C/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0237573A1 (en)	1987-09-23
US4786635A (en)	1988-11-22
AU6137186A (en)	1987-03-05
AU587057B2 (en)	1989-08-03
KR870700613A (ko)	1987-12-30
FI871322A0 (fi)	1987-03-26
EP0237573A4 (en)	1987-10-26
EP0237573B1 (en)	1992-01-15
NO170082B (no)	1992-06-01
DE3683483D1 (de)	1992-02-27
DK158087A (da)	1987-03-27
NO871314D0 (no)	1987-03-27
FI87352B (fi)	1992-09-15
FI871322A7 (fi)	1987-03-26
WO1987000838A1 (fr)	1987-02-12
KR890004196B1 (ko)	1989-10-27
FI87352C (fi)	1992-12-28
NO170082C (no)	1992-09-09
ATE71622T1 (de)	1992-02-15

Publication	Publication Date	Title
AU587057B2 (en)	1989-08-03	1,4-dihydro-3-oxo-2-(substituted phenyl)-benzothiazine derivatives
AU589565B2 (en)	1989-10-19	Substituted bicyclic compounds
GB9211172D0 (en)	1992-07-08	Compounds
NZ217418A (en)	1988-11-29	Tricyclic heterocyclic compounds and pharmaceutical compositions
IT1196423B (it)	1988-11-16	Benzotiazolin-composti
DE3375784D1 (en)	1988-04-07	1,3,4,6,7,11b-hexahydro-7-aryl-2h-pyrazino (2,1-alpha) isoquinolines useful as intermediates and pharmaceutical compounds and methods of preparation
ATE52776T1 (de)	1990-06-15	1-phenyl-3-benzazepine.
ES2014479B3 (es)	1990-07-16	Derivados de la quinoleina, su procedimiento de preparacion, su aplicacion a titulo de medicamento y las composiciones que les encierran.
DE3160719D1 (en)	1983-09-08	Benzothiopyrano(2,3-c) pyridines and their acid addition salts, their preparation, their use as medicaments and compositions containing them