DK159079A - Fremgangsmaade til fremstilling af derivater af 4-amino-2-piperidinoquinazolin eller syreadditionssalte deraf - Google Patents

Fremgangsmaade til fremstilling af derivater af 4-amino-2-piperidinoquinazolin eller syreadditionssalte deraf

Info

Publication number: DK159079A
Authority: DK; Denmark
Prior art keywords: piperidinoquinazoline; derivatives; amino; procedure; preparation
Prior art date: 1978-05-18

Application number

DK159079A

Other languages

English (en)

Inventor

S F Campbell

C J C Danilewicz

C W Greengrass

R Plews

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-05-18

Filing date

1979-04-18

Publication date

1979-11-19

1979-04-18 Application filed by Pfizer filed Critical Pfizer

1979-08-08 Priority to IE96379A priority Critical patent/IE47977B1/en

1979-11-19 Publication of DK159079A publication Critical patent/DK159079A/da

Links

MDGLKMXWHKGENE-UHFFFAOYSA-N 2-piperidin-1-ylquinazolin-4-amine Chemical class N=1C2=CC=CC=C2C(N)=NC=1N1CCCCC1 MDGLKMXWHKGENE-UHFFFAOYSA-N 0.000 title 1
239000002253 acid Substances 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK159079A 1978-05-18 1979-04-18 Fremgangsmaade til fremstilling af derivater af 4-amino-2-piperidinoquinazolin eller syreadditionssalte deraf DK159079A (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IE96379A IE47977B1 (en)	1978-05-18	1979-08-08	6,7-di(loweralkoxy)-4-amino-2-(substituted piperidino)quinazolines

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2035178		1978-05-18

Publications (1)

Publication Number	Publication Date
DK159079A true DK159079A (da)	1979-11-19

Family

ID=10144517

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK159079A DK159079A (da)	1978-05-18	1979-04-18	Fremgangsmaade til fremstilling af derivater af 4-amino-2-piperidinoquinazolin eller syreadditionssalte deraf

Country Status (30)

Country	Link
US (1)	US4243666A (da)
JP (1)	JPS554370A (da)
AR (2)	AR223487A1 (da)
AT (1)	ATA363379A (da)
AU (1)	AU512947B2 (da)
BE (1)	BE876297A (da)
CA (1)	CA1240325A (da)
CH (1)	CH643553A5 (da)
CS (1)	CS214796B2 (da)
DD (1)	DD143613A5 (da)
DE (1)	DE2919800A1 (da)
DK (1)	DK159079A (da)
ES (2)	ES480671A1 (da)
FI (1)	FI64589C (da)
FR (1)	FR2434162A1 (da)
GR (1)	GR72824B (da)
HU (1)	HU182562B (da)
IL (1)	IL57297A (da)
IN (1)	IN153045B (da)
IT (1)	IT1114222B (da)
LU (1)	LU81284A1 (da)
NL (1)	NL172157C (da)
NO (1)	NO791648L (da)
NZ (1)	NZ190465A (da)
PH (1)	PH14802A (da)
PL (2)	PL120651B1 (da)
PT (1)	PT69622A (da)
SE (1)	SE439306B (da)
YU (2)	YU115279A (da)
ZA (1)	ZA792390B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4607034A (en) *	1979-10-29	1986-08-19	Mitsubishi Yuka Pharmaceutical Co., Ltd.	Quinazoline derivatives and pharmaceutical composition thereof
JPS5962766U (ja) *	1982-06-30	1984-04-25	守田　智	小動物用給水器
GB8414518D0 (en) *	1984-06-07	1984-07-11	Pfizer Ltd	Therapeutic agents
US5801195A (en) *	1994-12-30	1998-09-01	Celgene Corporation	Immunotherapeutic aryl amides
US6248888B1 (en)	1997-11-14	2001-06-19	Teva Pharmaceutical Industries Ltd.	Process for the preparation of terazosin hydrochloride dihydrate
KR20030069218A (ko) *	2001-01-18	2003-08-25	다케다 야쿠힌 고교 가부시키가이샤	벤질피페리딘 화합물의 제조 방법
US6746460B2 (en) *	2002-08-07	2004-06-08	Satiety, Inc.	Intra-gastric fastening devices
CA2543710A1 (en) *	2003-11-03	2005-05-12	Warner-Lambert Company Llc	Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders
US20100210633A1 (en) *	2006-10-12	2010-08-19	Epix Delaware, Inc.	Carboxamide compounds and their use
KR101441930B1 (ko) *	2007-04-04	2014-09-19	시플라 리미티드	에르로티닙 및 그의 약학적으로 허용가능한 염의 제조방법
AU2008335135A1 (en)	2007-12-11	2009-06-18	Cytopathfinder, Inc.	Carboxamide compounds and their use as chemokine receptor agonists
BRPI0922010A2 (pt) *	2008-11-14	2015-12-15	Hoffmann La Roche	dervivados de quinazolina como antagonistas receptores de nk3

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1156973A (en) *	1965-07-06	1969-07-02		Quinazoline Derivatives
US3511836A (en) *	1967-12-13	1970-05-12	Pfizer & Co C	2,4,6,7-tetra substituted quinazolines
FR2321890A1 (fr) *	1975-08-26	1977-03-25	Synthelabo	Nouveaux derives de la quinazoline, leurs sels, leur preparation et les medicaments qui en renferment
DK140695C (da) *	1976-05-07	1980-05-12	Synthelabo	Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf

1979
- 1979-04-18 DK DK159079A patent/DK159079A/da not_active IP Right Cessation
- 1979-05-14 US US06/038,509 patent/US4243666A/en not_active Expired - Lifetime
- 1979-05-16 PH PH22500A patent/PH14802A/en unknown
- 1979-05-16 YU YU01152/79A patent/YU115279A/xx unknown
- 1979-05-16 IT IT22720/79A patent/IT1114222B/it active
- 1979-05-16 GR GR59104A patent/GR72824B/el unknown
- 1979-05-16 IN IN337/DEL/79A patent/IN153045B/en unknown
- 1979-05-16 NO NO791648A patent/NO791648L/no unknown
- 1979-05-16 PL PL1979215626A patent/PL120651B1/pl unknown
- 1979-05-16 CS CS793372A patent/CS214796B2/cs unknown
- 1979-05-16 BE BE0/195197A patent/BE876297A/xx unknown
- 1979-05-16 PL PL1979223844A patent/PL121158B1/pl unknown
- 1979-05-16 AU AU47101/79A patent/AU512947B2/en not_active Ceased
- 1979-05-16 AT AT0363379A patent/ATA363379A/de not_active IP Right Cessation
- 1979-05-16 NZ NZ190465A patent/NZ190465A/xx unknown
- 1979-05-16 FI FI791562A patent/FI64589C/fi not_active IP Right Cessation
- 1979-05-16 NL NLAANVRAGE7903853,A patent/NL172157C/xx not_active IP Right Cessation
- 1979-05-16 IL IL57297A patent/IL57297A/xx unknown
- 1979-05-16 AR AR276536A patent/AR223487A1/es active
- 1979-05-16 DE DE19792919800 patent/DE2919800A1/de not_active Ceased
- 1979-05-17 FR FR7912635A patent/FR2434162A1/fr active Granted
- 1979-05-17 CH CH459879A patent/CH643553A5/de not_active IP Right Cessation
- 1979-05-17 PT PT69622A patent/PT69622A/pt unknown
- 1979-05-17 CA CA000327839A patent/CA1240325A/en not_active Expired
- 1979-05-17 ZA ZA792390A patent/ZA792390B/xx unknown
- 1979-05-17 SE SE7904358A patent/SE439306B/sv not_active IP Right Cessation
- 1979-05-17 HU HU79PI678A patent/HU182562B/hu unknown
- 1979-05-17 ES ES480671A patent/ES480671A1/es not_active Expired
- 1979-05-17 JP JP6100079A patent/JPS554370A/ja active Granted
- 1979-05-17 LU LU81284A patent/LU81284A1/fr unknown
- 1979-05-18 DD DD79213010A patent/DD143613A5/de unknown
1980
- 1980-02-01 ES ES488210A patent/ES8101584A1/es not_active Expired
- 1980-10-28 AR AR283021A patent/AR224784A1/es active
1982
- 1982-11-16 YU YU02563/82A patent/YU256382A/xx unknown

Also Published As

Publication number	Publication date
ES488210A0 (es)	1980-12-16
SE7904358L (sv)	1979-11-19
CA1240325A (en)	1988-08-09
HU182562B (en)	1984-02-28
YU115279A (en)	1983-04-30
YU256382A (en)	1983-04-30
PL215626A1 (da)	1980-08-25
IN153045B (da)	1984-05-26
ZA792390B (en)	1980-07-30
NL172157C (nl)	1983-07-18
PL120651B1 (en)	1982-03-31
LU81284A1 (fr)	1980-12-16
AU512947B2 (en)	1980-11-06
IT7922720A0 (it)	1979-05-16
ES8101584A1 (es)	1980-12-16
FI64589C (fi)	1983-12-12
AR223487A1 (es)	1981-08-31
DD143613A5 (de)	1980-09-03
NO791648L (no)	1979-11-20
FI791562A7 (fi)	1979-11-19
PL223844A1 (da)	1981-01-02
IL57297A0 (en)	1979-09-30
FR2434162B1 (da)	1983-04-22
PH14802A (en)	1981-12-14
IL57297A (en)	1983-02-23
NL7903853A (nl)	1979-11-20
IT1114222B (it)	1986-01-27
US4243666A (en)	1981-01-06
NL172157B (nl)	1983-02-16
FR2434162A1 (fr)	1980-03-21
DE2919800A1 (de)	1979-11-22
JPS554370A (en)	1980-01-12
JPS5623992B2 (da)	1981-06-03
AU4710179A (en)	1979-11-22
ATA363379A (de)	1983-05-15
CH643553A5 (de)	1984-06-15
AR224784A1 (es)	1982-01-15
SE439306B (sv)	1985-06-10
CS214796B2 (en)	1982-05-28
GR72824B (da)	1983-12-06
NZ190465A (en)	1981-05-01
PT69622A (en)	1979-06-01
ES480671A1 (es)	1980-08-16
BE876297A (fr)	1979-11-16
FI64589B (fi)	1983-08-31
PL121158B1 (en)	1982-04-30

Legal Events

Date	Code	Title	Description
1989-04-17	AHS	Application shelved for other reasons than non-payment
2001-03-12	PBP	Patent lapsed

Publication	Publication Date	Title
DK178379A (da)	1979-11-04	Fremgangsmaade til fremstilling af n-substituerede moranolinderivater eller syreadditionssalte deraf
DK56077A (da)	1977-08-12	Fremgangsmade til fremstilling af 3-quinolincarboxylsyrederivater eller additionssalte deraf
DK147362C (da)	1988-06-27	Analogifremgangsmaade til fremstilling af ergolen- eller ergolin-derivater eller syreadditionssalte deraf
DK77279A (da)	1979-08-25	Fremgangsmaade til fremstilling af 3-imidazol-1-ylalkyl) indoler eller syreadditionssalte deraf
DK15279A (da)	1979-07-17	Fremgangsmaade til fremstilling af tetrahydropyridinylindolderivater eller additionssalte deraf
DK145260C (da)	1983-03-14	Analogifremgangsmaade til fremstilling af 4-acylamino-phenyl-ethanolaminer eller syreadditionssalte heraf
DK217481A (da)	1981-11-20	Fremgangsmaade til fremstilling af pyridoxinderivater eller syreadditionssalte deraf
DK392877A (da)	1978-03-04	Fremgangsmaade til fremstilling af phenylethylaminer eller syreadditionssalte heraf
DK149773C (da)	1987-03-23	Analogifremgangsmaade til fremstilling af 3-quinolincarboxylsyrederivater
DK157544C (da)	1990-06-25	Fremgangsmaade til fremstilling af imidazolylvinylaetere eller syreadditionssalte deraf
DK324979A (da)	1980-02-03	Fremgangsmaade til fremstilling af imidazoquinoxaliner eller salte deraf
DK20279A (da)	1979-07-19	Fremgangsmaade til fremstilling af 4-pyridon-3-carboxylsyrederivater
DK134580A (da)	1980-10-03	Fremgangsmaade til fremstilling af 2,6-diaminonebulariner eller syreadditionssalte deraf
DK226476A (da)	1976-11-25	Fremgangsmade til fremstilling af propargyl-2-phenylamino-imidazoliner-(2) eller syreadditionssalte heraf
DK296477A (da)	1978-01-04	Fremgangsmade til fremstilling af 2-brom-6-fluor-n-2-imidazolidinylidenbenzamin eller syreadditionssalte heraf
DK331679A (da)	1980-02-09	Fremgangsmaade til fremstilling af phenylalkansyrederivater
DK146066C (da)	1983-11-14	Analogifremgangsmaade til fremstilling af substituerede 2-phenylimino- imidazolidiner eller syreadditionssalte deraf
DK430379A (da)	1980-04-17	Fremgangsmaade til fremstilling af 2,6-diaminonebulariner eller syreadditionssalte deraf
DK257779A (da)	1979-12-22	Fremgangsmaade til fremstilling af chlor-styryl-cyclopropan-carboxylsyrederivater
DK386876A (da)	1977-02-28	Fremgangsmade til fremstilling af n-tetrahydrofurfuryl-noroxymorphoner eller syreadditionssalte deraf
DK438482A (da)	1983-04-06	Fremgangsmaade til fremstilling af indanderivater eller syreadditionssalte deraf
DK491678A (da)	1979-05-10	Fremgangsmaade til fremstilling af arylaetere af n-alkylpiperidiner eller syreadditionssalte deraf
DK115379A (da)	1979-09-23	Fremgangsmaade til fremstilling af dilignoler eller dilignollignende forbindelser eller salte heraf
DK172479A (da)	1979-10-29	Fremgangsmaade til fremstilling af n-alkenylmoranolinderivater eller syreadditionssalte deraf
DK553982A (da)	1983-06-15	Fremgangsmaade til fremstilling af omt-esterderivater eller syreadditionssalte deraf