JPS554370A - 44aminoo22piperidinoquinazoline derivative* its manufacture and cardiovascular controlling agent made thereof - Google Patents

44aminoo22piperidinoquinazoline derivative* its manufacture and cardiovascular controlling agent made thereof

Info

Publication number
JPS554370A
JPS554370A JP6100079A JP6100079A JPS554370A JP S554370 A JPS554370 A JP S554370A JP 6100079 A JP6100079 A JP 6100079A JP 6100079 A JP6100079 A JP 6100079A JP S554370 A JPS554370 A JP S554370A
Authority
JP
Japan
Prior art keywords
cardiovascular
derivative
manufacture
controlling agent
agent made
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6100079A
Other languages
English (en)
Other versions
JPS5623992B2 (ja
Inventor
Fureizaa Kiyanberu Saimon
Kurisutofuaa Daniruuitsu Jiyon
Uiriamu Guriingurasu Korin
Buriyuuzu Roona
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Original Assignee
PFIZER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER filed Critical PFIZER
Publication of JPS554370A publication Critical patent/JPS554370A/ja
Publication of JPS5623992B2 publication Critical patent/JPS5623992B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP6100079A 1978-05-18 1979-05-17 44aminoo22piperidinoquinazoline derivative* its manufacture and cardiovascular controlling agent made thereof Granted JPS554370A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2035178 1978-05-18

Publications (2)

Publication Number Publication Date
JPS554370A true JPS554370A (en) 1980-01-12
JPS5623992B2 JPS5623992B2 (ja) 1981-06-03

Family

ID=10144517

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6100079A Granted JPS554370A (en) 1978-05-18 1979-05-17 44aminoo22piperidinoquinazoline derivative* its manufacture and cardiovascular controlling agent made thereof

Country Status (30)

Country Link
US (1) US4243666A (ja)
JP (1) JPS554370A (ja)
AR (2) AR223487A1 (ja)
AT (1) ATA363379A (ja)
AU (1) AU512947B2 (ja)
BE (1) BE876297A (ja)
CA (1) CA1240325A (ja)
CH (1) CH643553A5 (ja)
CS (1) CS214796B2 (ja)
DD (1) DD143613A5 (ja)
DE (1) DE2919800A1 (ja)
DK (1) DK159079A (ja)
ES (2) ES480671A1 (ja)
FI (1) FI64589C (ja)
FR (1) FR2434162A1 (ja)
GR (1) GR72824B (ja)
HU (1) HU182562B (ja)
IL (1) IL57297A (ja)
IN (1) IN153045B (ja)
IT (1) IT1114222B (ja)
LU (1) LU81284A1 (ja)
NL (1) NL172157C (ja)
NO (1) NO791648L (ja)
NZ (1) NZ190465A (ja)
PH (1) PH14802A (ja)
PL (2) PL121158B1 (ja)
PT (1) PT69622A (ja)
SE (1) SE439306B (ja)
YU (2) YU115279A (ja)
ZA (1) ZA792390B (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5962766U (ja) * 1982-06-30 1984-04-25 守田　智 小動物用給水器
JP2008019269A (ja) * 1994-12-30 2008-01-31 Celgene Corp 新規免疫治療用アリールアミド類
JP2011506466A (ja) * 2007-12-11 2011-03-03 株式会社サイトパスファインダー カルボキサミド化合物ならびにケモカイン受容体アゴニストとしてのそれらの使用
JP2012508266A (ja) * 2008-11-14 2012-04-05 エフ．ホフマン−ラ ロシュ アーゲー Ｎｋ３受容体アンタゴニストとしてのキナゾリン誘導体

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607034A (en) * 1979-10-29 1986-08-19 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinazoline derivatives and pharmaceutical composition thereof
GB8414518D0 (en) * 1984-06-07 1984-07-11 Pfizer Ltd Therapeutic agents
US6248888B1 (en) 1997-11-14 2001-06-19 Teva Pharmaceutical Industries Ltd. Process for the preparation of terazosin hydrochloride dihydrate
CN1494529A (zh) * 2001-01-18 2004-05-05 武田药品工业株式会社 苄基哌啶化合物的制备方法
US6746460B2 (en) * 2002-08-07 2004-06-08 Satiety, Inc. Intra-gastric fastening devices
BRPI0415683A (pt) * 2003-11-03 2006-12-19 Warner Lambert Co inibidores da reabsorção de norepinefrina para o tratamento de distúrbios do sistema nervoso central
CL2007002958A1 (es) * 2006-10-12 2008-05-09 Epix Delaware Inc Compuestos derivados de heteroaril-carboxamida, antagonistas del receptor de quimioquina; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades tales como rechazo de transplante de organos, artritis reumatoidea, lupus, entr
NZ579997A (en) * 2007-04-04 2012-08-31 Cipla Ltd PROCESS FOR PREPARATION OF N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
FR2321890A1 (fr) * 1975-08-26 1977-03-25 Synthelabo Nouveaux derives de la quinazoline, leurs sels, leur preparation et les medicaments qui en renferment
DK140695C (da) * 1976-05-07 1980-05-12 Synthelabo Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5962766U (ja) * 1982-06-30 1984-04-25 守田　智 小動物用給水器
JP2008019269A (ja) * 1994-12-30 2008-01-31 Celgene Corp 新規免疫治療用アリールアミド類
JP2011506466A (ja) * 2007-12-11 2011-03-03 株式会社サイトパスファインダー カルボキサミド化合物ならびにケモカイン受容体アゴニストとしてのそれらの使用
JP2012508266A (ja) * 2008-11-14 2012-04-05 エフ．ホフマン−ラ ロシュ アーゲー Ｎｋ３受容体アンタゴニストとしてのキナゾリン誘導体

Also Published As

Publication number Publication date
PL223844A1 (ja) 1981-01-02
FI64589C (fi) 1983-12-12
ES488210A0 (es) 1980-12-16
AU512947B2 (en) 1980-11-06
IT1114222B (it) 1986-01-27
DE2919800A1 (de) 1979-11-22
ES480671A1 (es) 1980-08-16
US4243666A (en) 1981-01-06
LU81284A1 (fr) 1980-12-16
YU115279A (en) 1983-04-30
PL120651B1 (en) 1982-03-31
AR224784A1 (es) 1982-01-15
YU256382A (en) 1983-04-30
AR223487A1 (es) 1981-08-31
FR2434162B1 (ja) 1983-04-22
NL172157B (nl) 1983-02-16
FI791562A7 (fi) 1979-11-19
NL172157C (nl) 1983-07-18
GR72824B (ja) 1983-12-06
DD143613A5 (de) 1980-09-03
CS214796B2 (en) 1982-05-28
FR2434162A1 (fr) 1980-03-21
DK159079A (da) 1979-11-19
BE876297A (fr) 1979-11-16
SE439306B (sv) 1985-06-10
ATA363379A (de) 1983-05-15
PL215626A1 (ja) 1980-08-25
SE7904358L (sv) 1979-11-19
HU182562B (en) 1984-02-28
NZ190465A (en) 1981-05-01
PH14802A (en) 1981-12-14
IL57297A0 (en) 1979-09-30
NL7903853A (nl) 1979-11-20
PT69622A (en) 1979-06-01
PL121158B1 (en) 1982-04-30
AU4710179A (en) 1979-11-22
FI64589B (fi) 1983-08-31
NO791648L (no) 1979-11-20
IT7922720A0 (it) 1979-05-16
IL57297A (en) 1983-02-23
CA1240325A (en) 1988-08-09
ES8101584A1 (es) 1980-12-16
CH643553A5 (de) 1984-06-15
ZA792390B (en) 1980-07-30
JPS5623992B2 (ja) 1981-06-03
IN153045B (ja) 1984-05-26

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