DK1592402T3 - Dispersion af smagsmaskerede krystaller eller granulat af aktive stoffer, bløde tyggekapsler fyldt med dispersionen samt fremgangsmåde til dens fremstilling - Google Patents

Dispersion af smagsmaskerede krystaller eller granulat af aktive stoffer, bløde tyggekapsler fyldt med dispersionen samt fremgangsmåde til dens fremstilling

Info

Publication number
DK1592402T3
DK1592402T3 DK04704035.7T DK04704035T DK1592402T3 DK 1592402 T3 DK1592402 T3 DK 1592402T3 DK 04704035 T DK04704035 T DK 04704035T DK 1592402 T3 DK1592402 T3 DK 1592402T3
Authority
DK
Denmark
Prior art keywords
dispersion
masked
taste
granules
crystals
Prior art date
Application number
DK04704035.7T
Other languages
English (en)
Inventor
Julien Meissonnier
Fabrice Rose
Marie Madeleine Bohn
Original Assignee
Rp Scherer Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rp Scherer Technologies Llc filed Critical Rp Scherer Technologies Llc
Application granted granted Critical
Publication of DK1592402T3 publication Critical patent/DK1592402T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
DK04704035.7T 2003-01-24 2004-01-21 Dispersion af smagsmaskerede krystaller eller granulat af aktive stoffer, bløde tyggekapsler fyldt med dispersionen samt fremgangsmåde til dens fremstilling DK1592402T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0300824A FR2850275B1 (fr) 2003-01-24 2003-01-24 Capsules molles a macher contenant une substance active a gout masque
PCT/US2004/001463 WO2004066925A2 (en) 2003-01-24 2004-01-21 Dispersion of taste masked crystals or granules of active substances, chewable soft capsules filled with said dispersion, and process for preparing same

Publications (1)

Publication Number Publication Date
DK1592402T3 true DK1592402T3 (da) 2013-06-24

Family

ID=32669215

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04704035.7T DK1592402T3 (da) 2003-01-24 2004-01-21 Dispersion af smagsmaskerede krystaller eller granulat af aktive stoffer, bløde tyggekapsler fyldt med dispersionen samt fremgangsmåde til dens fremstilling

Country Status (18)

Country Link
EP (1) EP1592402B1 (da)
JP (1) JP5371187B2 (da)
CN (2) CN103169655A (da)
AR (1) AR042902A1 (da)
AU (1) AU2004207498B2 (da)
BR (1) BRPI0406913B8 (da)
CA (1) CA2512988C (da)
DK (1) DK1592402T3 (da)
ES (1) ES2415660T3 (da)
FR (1) FR2850275B1 (da)
MX (1) MXPA05007683A (da)
NO (1) NO339528B1 (da)
NZ (1) NZ541753A (da)
PT (1) PT1592402E (da)
RU (1) RU2362546C2 (da)
SI (1) SI1592402T1 (da)
UA (1) UA84140C2 (da)
WO (1) WO2004066925A2 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1656117A1 (en) * 2003-08-11 2006-05-17 Merck Frosst Canada Ltd. Flavored taste-masked pharmaceutical formulation made using a one-step coating process
US8124072B2 (en) 2003-09-29 2012-02-28 Soft Gel Technologies, Inc. Solubilized CoQ-10
US7169385B2 (en) 2003-09-29 2007-01-30 Ronald G. Udell Solubilized CoQ-10 and carnitine
WO2005032278A1 (en) 2003-09-29 2005-04-14 Soft Gel Technologies, Inc. SOLUBILIZED CoQ-10
US20080020022A1 (en) * 2006-06-05 2008-01-24 Udell Ronald G Chewable co-enzyme q-10 capsule
US20070292501A1 (en) * 2006-06-05 2007-12-20 Udell Ronald G Chewable soft gelatin capsules
US8343541B2 (en) 2007-03-15 2013-01-01 Soft Gel Technologies, Inc. Ubiquinol and alpha lipoic acid compositions
WO2009011449A2 (en) * 2007-07-19 2009-01-22 R-Tech Ueno, Ltd. Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound
FR2935084B1 (fr) * 2008-08-19 2011-05-06 Pancosma Sa Pour L Ind Des Produits Biochimiques Additif pour l'alimentation animale et son procede de preparation
GB201006218D0 (en) 2010-04-14 2010-06-02 Ayanda As Composition
CA3065589C (en) * 2010-06-03 2022-04-26 Catalent Ontario Limited Multi phase soft gel capsules, apparatus and method thereof
CA2706270C (en) 2010-06-03 2020-01-07 Accucaps Industries Limited Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation
MX349803B (es) * 2011-02-11 2017-08-14 Ctc Bio Inc Preparación farmacéutica de película que contiene sildenafil en su forma de base libre y método para producir dicha preparación.
CA3023121A1 (en) * 2011-04-11 2012-10-18 Vitux Group As Oral pharmaceutical dispersion compositions
WO2012144943A1 (en) * 2011-04-18 2012-10-26 Lipidor Ab Liquid carrier for oral delivery of a pharmacologically active agent
CN102241782B (zh) * 2011-05-18 2013-01-30 清华大学 一种淀粉乙酸酯的制备方法及其在去除水中硝酸盐的应用
CN102813275B (zh) 2011-06-10 2015-09-30 杭州养生堂保健品有限公司 一种咀嚼型软胶囊皮和咀嚼型软胶囊
DE102012014848A1 (de) * 2012-07-27 2012-10-31 Heilerde-Gesellschaft Luvos Just GmbH & Co. KG Heilerde-Zubereitung
US20150209360A1 (en) * 2014-01-30 2015-07-30 Orbz, Llc Oral caffeine delivery composition
FR3027802B1 (fr) 2014-10-31 2018-03-02 Ethypharm Granules de principe actif a double masquage de gout, leur procede de preparation et comprimes orodispersibles les contenant
EP4360653A3 (en) 2015-03-26 2024-07-31 Patheon Softgels Inc. Liquisoft capsules
KR102865751B1 (ko) * 2016-03-15 2025-09-29 에이서 테라퓨틱스 인크. 소듐 페닐부티레이트를 포함하는 맛우수한 조성물 및 그의 용도
JP6942342B2 (ja) * 2016-11-02 2021-09-29 富士カプセル株式会社 ソフトカプセル皮膜
JP2018121699A (ja) * 2017-01-30 2018-08-09 株式会社アクレス クリルオイルを充填したカプセル剤
CN107373744B (zh) * 2017-07-13 2018-11-09 云南中烟工业有限责任公司 一种维生素c微胶囊的制备方法及其在卷烟中的应用
CN108524464A (zh) * 2018-05-17 2018-09-14 安士制药（中山）有限公司 一种西甲硅油软胶囊的制备方法
TWI849062B (zh) 2019-02-22 2024-07-21 英商康泰倫特英國斯文敦載迪斯有限公司 保存水性懸浮液中以無溶劑混合方法製備的功能性塗覆之活性醫藥成份微粒
CN113507923B (zh) 2019-02-22 2024-03-26 康特伦英国斯温顿捷迪斯有限公司 在线混合期间混悬液的曝气最小化
GB2585413B (en) 2019-02-22 2023-04-26 Catalent Uk Swindon Zydis Ltd Minimizing agglomeration of drug particle coating material during storage to stabilize disintegration times of pharmaceutical products
WO2020169989A1 (en) * 2019-02-22 2020-08-27 Catalent U.K. Swindon Zydis Limited Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising ibuprofen
BR112023001716A2 (pt) 2020-07-31 2023-04-04 Catalent Uk Swindon Zydis Ltd Composições farmacêuticas compreendendo api revestido
US20230414597A1 (en) 2020-11-18 2023-12-28 BioPharma Synergies, S. L. Orodispersible powder composition comprising an antihistamine compound

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8623557D0 (en) 1986-10-01 1986-11-05 Boots Co Plc Therapeutic agents
US4851226A (en) * 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
GB8813682D0 (en) * 1988-06-09 1988-07-13 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
CH677606A5 (da) 1988-07-12 1991-06-14 Aesculapius Pharma Sa
US4975465A (en) 1989-03-28 1990-12-04 American Home Products Corporation Orally administrable ibuprofen compositions
CA2063141C (en) * 1989-08-04 1997-03-04 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5262179A (en) 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
AU639988B2 (en) 1990-04-11 1993-08-12 Pharmacia & Upjohn Company Taste masking of ibuprofen by fluid bed coating
JP3157233B2 (ja) * 1991-11-22 2001-04-16 エーザイ株式会社 水溶性薬物を含有した軟カプセル剤
JP3136310B2 (ja) * 1992-02-26 2001-02-19 東洋カプセル株式会社 咀嚼服用に適した担体
IT1256022B (it) * 1992-06-08 1995-11-20 Preparazioni farmaceutiche stabili di nicorandil
CA2146999A1 (en) * 1992-10-16 1994-04-28 Stephen John Douglas Taste-masking compositions of ranitidine
GB9313329D0 (en) * 1993-06-28 1993-08-11 Scherer Ltd R P Softgel capsule shell compositions
US5466865A (en) 1993-07-02 1995-11-14 Ibah, Inc. Neomorphic ibuprofen and methods of using same
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
ZA945944B (en) 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
US5569466A (en) * 1995-05-17 1996-10-29 R. P. Scherer Corporation Fill compositions for soft elastic gel capsules
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
FR2785539B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
WO2000051570A1 (fr) * 1999-02-26 2000-09-08 Shionogi & Co., Ltd. Capsules molles a croquer presentant des proprietes d'administration ameliorees et leur procede de production
FR2795962B1 (fr) 1999-07-08 2003-05-09 Prographarm Laboratoires Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
CA2447693A1 (en) * 2001-05-31 2002-12-05 Cima Labs Inc. Taste-masking of highly water-soluble drugs

Also Published As

Publication number Publication date
RU2362546C2 (ru) 2009-07-27
PT1592402E (pt) 2013-06-25
HK1082659A1 (en) 2006-06-16
NO20053681L (no) 2005-08-23
JP5371187B2 (ja) 2013-12-18
CN103169655A (zh) 2013-06-26
CA2512988C (en) 2015-11-10
EP1592402B1 (en) 2013-03-20
BRPI0406913B1 (pt) 2016-03-01
WO2004066925B1 (en) 2004-12-09
WO2004066925A3 (en) 2004-10-28
AU2004207498A1 (en) 2004-08-12
AU2004207498B2 (en) 2008-10-30
UA84140C2 (ru) 2008-09-25
NZ541753A (en) 2008-12-24
EP1592402A4 (en) 2009-01-14
WO2004066925A2 (en) 2004-08-12
FR2850275B1 (fr) 2005-04-08
CA2512988A1 (en) 2004-08-12
BRPI0406913A (pt) 2006-01-03
RU2005126729A (ru) 2006-03-10
CN1741787A (zh) 2006-03-01
MXPA05007683A (es) 2005-09-30
ES2415660T3 (es) 2013-07-26
BRPI0406913B8 (pt) 2021-05-25
SI1592402T1 (sl) 2013-08-30
EP1592402A2 (en) 2005-11-09
NO339528B1 (no) 2016-12-27
JP2007525413A (ja) 2007-09-06
FR2850275A1 (fr) 2004-07-30
AR042902A1 (es) 2005-07-06

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