DK1601770T3 - Streptococcus pyogenes antigener - Google Patents

Streptococcus pyogenes antigener

Info

Publication number
DK1601770T3
DK1601770T3 DK04716233T DK04716233T DK1601770T3 DK 1601770 T3 DK1601770 T3 DK 1601770T3 DK 04716233 T DK04716233 T DK 04716233T DK 04716233 T DK04716233 T DK 04716233T DK 1601770 T3 DK1601770 T3 DK 1601770T3
Authority
DK
Denmark
Prior art keywords
antigenes
streptococcus pyogenes
antigens
hyperimmune serum
serum reactive
Prior art date
Application number
DK04716233T
Other languages
English (en)
Inventor
Andreas Meinke
Eszter Nagy
Dieter Gelbmann
Birgit Winkler
Original Assignee
Intercell Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intercell Ag filed Critical Intercell Ag
Application granted granted Critical
Publication of DK1601770T3 publication Critical patent/DK1601770T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0208—Specific bacteria not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK04716233T 2003-03-04 2004-03-02 Streptococcus pyogenes antigener DK1601770T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03450061 2003-03-04
PCT/EP2004/002087 WO2004078907A2 (en) 2003-03-04 2004-03-02 Streptococcus pyogenes antigens

Publications (1)

Publication Number Publication Date
DK1601770T3 true DK1601770T3 (da) 2009-11-02

Family

ID=32946995

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04716233T DK1601770T3 (da) 2003-03-04 2004-03-02 Streptococcus pyogenes antigener

Country Status (15)

Country Link
US (3) US7638136B2 (da)
EP (8) EP2287315A1 (da)
JP (2) JP2006520202A (da)
CN (2) CN1756843B (da)
AT (1) ATE441715T1 (da)
AU (2) AU2004218284B2 (da)
CA (1) CA2517518A1 (da)
CY (1) CY1109683T1 (da)
DE (1) DE602004022923D1 (da)
DK (1) DK1601770T3 (da)
ES (1) ES2330334T3 (da)
PL (1) PL1601770T3 (da)
PT (1) PT1601770E (da)
SI (1) SI1601770T1 (da)
WO (1) WO2004078907A2 (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2881568C (en) * 2000-10-27 2019-09-24 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from streptococcus groups a & b
BRPI0207447B1 (pt) 2001-02-21 2015-09-22 Id Biomedical Corp polipeptídeo recombinante isolado, seu uso e processo de produção, vetor de expressão, célula hospedeira microbiana transgênica, composição farmacêutica, uso da dita composição, métodos de detecção e kit
US20070053924A1 (en) * 2002-08-26 2007-03-08 Herve Tettelin Conserved and specific streptococcal genomes
ITRM20030376A1 (it) 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
ES2505695T3 (es) 2003-07-31 2014-10-10 Novartis Vaccines And Diagnostics, Inc. Composiciones inmunógenas para Streptococcus pyogenes
US8945589B2 (en) * 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
JP2008508320A (ja) 2004-07-29 2008-03-21 カイロン コーポレイション Ｓｔｒｅｐｔｏｃｏｃｃｕｓａｇａｌａｃｔｉａｅのようなグラム陽性細菌に対する免疫原性組成物
US7838010B2 (en) * 2004-10-08 2010-11-23 Novartis Vaccines And Diagnostics S.R.L. Immunogenic and therapeutic compositions for Streptococcus pyogenes
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
AU2006261342B2 (en) 2005-06-15 2012-02-02 The Ohio State University Research Foundation Her-2 peptides
DK2341149T3 (da) * 2005-08-26 2017-02-27 Dupont Nutrition Biosci Aps Anvendelse af CRISPR-associerede gener (Cas)
PT2054431E (pt) * 2006-06-09 2011-11-03 Novartis Ag Confórmeros de adesinas bacterianas
EP2292644A3 (en) 2006-07-07 2011-05-25 Intercell AG Small Streptococcus pyogenes antigens and their use
CA2668018A1 (en) * 2006-10-30 2008-09-12 Novartis Ag Immunogenic and therapeutic compositions for streptococcus pyogenes
BRPI0604997A (pt) 2006-11-30 2007-05-22 Fundacao Zerbini vacina contra o estreptococo beta hemolìtico do grupo a, e respectivo processo de obtenção
GB0624874D0 (en) 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
CA2684570A1 (en) 2007-04-19 2008-10-30 Molecular Detection Inc. Methods, compositions and kits for detection and analysis of antibiotic-resistant bacteria
WO2009003291A1 (en) * 2007-07-03 2009-01-08 Mount Sinai Hospital Therapeutics and diagnostics for group a streptococci
KR101621837B1 (ko) 2007-09-12 2016-05-17 노파르티스 아게 Ｇａｓ57 돌연변이 항원 및 ｇａｓ57 항체
AU2013203022B2 (en) * 2007-09-12 2015-09-03 Glaxosmithkline Biologicals S.A. GAS57 mutant antigens and GAS57 antibodies
EP2537857B1 (en) 2007-12-21 2017-01-18 GlaxoSmithKline Biologicals SA Mutant forms of streptolysin O
AU2009259951A1 (en) 2008-06-20 2009-12-23 Wyeth Llc Compositions and methods of use of ORF 554 from beta hemolytic Streptococcal strains
MX2011004755A (es) * 2008-11-05 2011-10-10 Wyeth Llc Composicion inmunogenica multicomponente para la prevencion de enfermedad estreptococica beta-hemolitica (bhs).
US20100234283A1 (en) 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
GB0918392D0 (en) * 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
WO2013166281A1 (en) * 2012-05-02 2013-11-07 Cedars-Sinai Medical Center Bi-functional compositions for targeting cells to diseased tissues and methods of using same
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
US9249392B2 (en) 2010-04-30 2016-02-02 Cedars-Sinai Medical Center Methods and compositions for maintaining genomic stability in cultured stem cells
US9884076B2 (en) 2012-06-05 2018-02-06 Capricor, Inc. Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
EP3563859B1 (en) 2012-08-13 2021-10-13 Cedars-Sinai Medical Center Cardiosphere-derived exosomes for tissue regeneration
WO2014124446A1 (en) * 2013-02-11 2014-08-14 University Of Tennessee Research Foundation Group a streptococcal m-related proteins and methods of use
EP4494699A3 (en) 2014-10-03 2025-04-30 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
GB201502306D0 (en) * 2015-02-12 2015-04-01 Hansa Medical Ab Protein
US10329601B2 (en) * 2015-12-28 2019-06-25 Ionian Technologies, Inc. Nicking and extension amplification reaction (NEAR) of Streptococcus species
WO2017123662A1 (en) 2016-01-11 2017-07-20 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
WO2017210652A1 (en) 2016-06-03 2017-12-07 Cedars-Sinai Medical Center Cdc-derived exosomes for treatment of ventricular tachyarrythmias
US11541078B2 (en) 2016-09-20 2023-01-03 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
JP7336769B2 (ja) 2017-04-19 2023-09-01 シーダーズ―シナイ メディカル センター 骨格筋ジストロフィーを治療する方法及び組成物
AU2018256755A1 (en) * 2017-04-26 2019-12-05 Auckland Uniservices Limited Analytical and therapeutic methods and compositions, and uses thereof
WO2019126068A1 (en) 2017-12-20 2019-06-27 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
EP3749344A4 (en) 2018-02-05 2022-01-26 Cedars-Sinai Medical Center METHODS OF THERAPEUTIC USE OF EXOSOMES AND Y-RNAS
JP2020117470A (ja) * 2019-01-25 2020-08-06 公益財団法人ヒューマンサイエンス振興財団 抗体並びに劇症型溶血性レンサ球菌感染症を予防及び／又は治療するための薬剤
CN110438261B (zh) * 2019-07-29 2022-08-12 华南农业大学 用于检测f亚群禽白血病病毒的分子标记、引物、试剂盒及应用
US20250000962A1 (en) * 2021-07-29 2025-01-02 Université de Lausanne Pneumococcal polypeptide antigens
CN116855486B (zh) * 2023-07-21 2024-11-15 临沂大学 一种链球菌前噬菌体裂解酶lys1644及应用
CN117417427B (zh) * 2023-09-11 2024-05-07 江苏省人民医院（南京医科大学第一附属医院） 一种检测内源性自体胰岛素介导的胰岛素抗体的试剂盒

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB234771A (en) * 1924-06-02 1926-02-11 S T Leigh And Company Ltd Improved means for inserting cork discs, or the like, into caps or covers
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
ES2259800T3 (es) 1990-06-11 2006-10-16 Gilead Sciences, Inc. Procedimientos de uso de ligandos de acido nucleico.
DK0464533T3 (da) 1990-06-28 1999-04-26 Gen Hospital Corp Fusionsproteiner med immunglobulindele, deres fremstilling og anvendelse
ES2188583T3 (es) * 1991-06-24 2003-07-01 Chiron Corp Polipeptidos para el virus de la hepatitis c (hcv).
EP1167379A3 (en) 1994-07-15 2004-09-08 University Of Iowa Research Foundation Immunomodulatory oligonucleotides
EA199800046A1 (ru) * 1995-06-07 1998-06-25 Байокем Вэксинс Инк. Полипептид, последовательность днк, вакцинная композиция (варианты), антитело или его фрагмент, вакцина, применения указанных полипептида, последовательности днк и антитела или его фрагмента
RS50101B (sr) 1996-02-24 2009-01-22 Boehringer Ingelheim International Gmbh., Farmaceutski preparati za imunomodulaciju
DE59708838D1 (de) 1996-08-30 2003-01-09 Jens Peter Fuerste Spiegelselektion und spiegelevolution von nucleinsäuren
US5849902A (en) 1996-09-26 1998-12-15 Oligos Etc. Inc. Three component chimeric antisense oligonucleotides
US5989912A (en) 1996-11-21 1999-11-23 Oligos Etc. Inc. Three component chimeric antisense oligonucleotides
JP3515314B2 (ja) * 1997-03-25 2004-04-05 扶桑薬品工業株式会社 ストレプトコッカス・ピオゲネス菌に起因する感染症の診断用プローブ
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
DE19803453A1 (de) 1998-01-30 1999-08-12 Boehringer Ingelheim Int Vakzine
KR100802198B1 (ko) 1998-12-23 2008-02-11 샤이어 바이오켐 인코포레이티드 신규한 스트렙토코커스 항원
AT408721B (de) 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
WO2001049721A2 (en) 1999-12-30 2001-07-12 Bristol-Myers Squibb Company Bacterial genes and proteins that are essential for cell viability and their uses
AT409085B (de) 2000-01-28 2002-05-27 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
ATE375169T1 (de) 2000-04-14 2007-10-15 Intercell Ag Modifizierte peptide enthaltende pharmazeutische präparationen
RU2413520C2 (ru) 2000-06-08 2011-03-10 Интерселл Аг Вакцинная композиция, содержащая иммуностимулирующие олигодезоксинуклеотиды
AT410173B (de) 2000-06-08 2003-02-25 Cistem Biotechnologies Gmbh Antigene zusammensetzung
WO2002005448A1 (en) 2000-07-10 2002-01-17 Telefonaktiebolaget Lm Ericsson (Publ) Resource management in uncoordinated frequency hopping system
CA2418854A1 (en) 2000-08-17 2002-02-21 Jorg Fritz A vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide or a derivative thereof
AT410635B (de) 2000-10-18 2003-06-25 Cistem Biotechnologies Gmbh Vakzin-zusammensetzung
CA2881568C (en) * 2000-10-27 2019-09-24 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from streptococcus groups a & b
AT410798B (de) 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
BRPI0207447B1 (pt) * 2001-02-21 2015-09-22 Id Biomedical Corp polipeptídeo recombinante isolado, seu uso e processo de produção, vetor de expressão, célula hospedeira microbiana transgênica, composição farmacêutica, uso da dita composição, métodos de detecção e kit
AU2002306849A1 (en) * 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
GB0107658D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
BR0208874A (pt) * 2001-04-13 2004-06-22 Wyeth Corp Proteìnas superficiais de streptococcus pyogenes
EP2277897A1 (en) 2001-04-16 2011-01-26 Wyeth Holdings Corporation Streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof
FR2824074A1 (fr) * 2001-04-26 2002-10-31 Pasteur Institut Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques
GB0210128D0 (en) * 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
NZ540731A (en) * 2002-12-20 2008-04-30 Univ New Jersey Med Compositions and methods for enzymatic detachment of bacterial and fungal biofilms
ES2505695T3 (es) * 2003-07-31 2014-10-10 Novartis Vaccines And Diagnostics, Inc. Composiciones inmunógenas para Streptococcus pyogenes
EP2292644A3 (en) * 2006-07-07 2011-05-25 Intercell AG Small Streptococcus pyogenes antigens and their use
EP2045869A1 (de) 2007-10-02 2009-04-08 Rohde & Schwarz GmbH & Co. KG Richtkoppler

Also Published As

Publication number Publication date
EP2287315A1 (en) 2011-02-23
WO2004078907A2 (en) 2004-09-16
US20100255034A1 (en) 2010-10-07
CY1109683T1 (el) 2014-08-13
US20130122047A1 (en) 2013-05-16
US7638136B2 (en) 2009-12-29
HK1084977A1 (en) 2006-08-11
JP2006520202A (ja) 2006-09-07
EP2290082A1 (en) 2011-03-02
CA2517518A1 (en) 2004-09-16
EP1601770A2 (en) 2005-12-07
CN102512670A (zh) 2012-06-27
US8349336B2 (en) 2013-01-08
SI1601770T1 (sl) 2010-01-29
PL1601770T3 (pl) 2010-02-26
EP2287313A1 (en) 2011-02-23
DE602004022923D1 (de) 2009-10-15
EP1601770B1 (en) 2009-09-02
AU2004218284A1 (en) 2004-09-16
EP2287311A1 (en) 2011-02-23
EP2287312A1 (en) 2011-02-23
CN1756843B (zh) 2012-03-21
AU2009230772A1 (en) 2009-11-26
WO2004078907A3 (en) 2005-03-10
EP2053125A1 (en) 2009-04-29
US20060194751A1 (en) 2006-08-31
EP2287314A1 (en) 2011-02-23
PT1601770E (pt) 2009-12-07
EP2053125B1 (en) 2014-04-30
JP2011015689A (ja) 2011-01-27
ATE441715T1 (de) 2009-09-15
AU2004218284B2 (en) 2009-07-23
AU2009230772B2 (en) 2013-07-18
CN1756843A (zh) 2006-04-05
ES2330334T3 (es) 2009-12-09

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