DK160601C - Farmaceutisk harpiksholdigt, sustained release praeparat med kontrolleret afgivelse af et farmaceutisk acceptabelt syreadditionssalt af dextromethorphan samt fremgangsmaade til fremstilling deraf - Google Patents
Farmaceutisk harpiksholdigt, sustained release praeparat med kontrolleret afgivelse af et farmaceutisk acceptabelt syreadditionssalt af dextromethorphan samt fremgangsmaade til fremstilling derafInfo
- Publication number
- DK160601C DK160601C DK589086A DK589086A DK160601C DK 160601 C DK160601 C DK 160601C DK 589086 A DK589086 A DK 589086A DK 589086 A DK589086 A DK 589086A DK 160601 C DK160601 C DK 160601C
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical
- dextromethorphan
- responsible
- procedures
- preparing
- Prior art date
Links
- MKXZASYAUGDDCJ-SZMVWBNQSA-N LSM-2525 Chemical compound C1CCC[C@H]2[C@@]3([H])N(C)CC[C@]21C1=CC(OC)=CC=C1C3 MKXZASYAUGDDCJ-SZMVWBNQSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 238000013270 controlled release Methods 0.000 title 1
- 239000003405 delayed action preparation Substances 0.000 title 1
- 229960001985 dextromethorphan Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/806,879 US4788055A (en) | 1985-12-09 | 1985-12-09 | Resinate sustained release dextromethorphan composition |
| US80687985 | 1985-12-09 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK589086D0 DK589086D0 (da) | 1986-12-08 |
| DK589086A DK589086A (da) | 1987-06-10 |
| DK160601B DK160601B (da) | 1991-04-02 |
| DK160601C true DK160601C (da) | 1991-09-02 |
Family
ID=25195036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK589086A DK160601C (da) | 1985-12-09 | 1986-12-08 | Farmaceutisk harpiksholdigt, sustained release praeparat med kontrolleret afgivelse af et farmaceutisk acceptabelt syreadditionssalt af dextromethorphan samt fremgangsmaade til fremstilling deraf |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4788055A (da) |
| EP (1) | EP0225615A3 (da) |
| JP (1) | JPS62138428A (da) |
| AU (1) | AU597316B2 (da) |
| DK (1) | DK160601C (da) |
| FI (1) | FI87525C (da) |
| IE (1) | IE863209L (da) |
| NO (1) | NO864918L (da) |
| PT (1) | PT83877B (da) |
| ZA (1) | ZA869255B (da) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894239A (en) * | 1987-06-02 | 1990-01-16 | Takeda Chemical Industries, Ltd. | Sustained-release preparation and production thereof |
| US4892877A (en) * | 1987-10-27 | 1990-01-09 | Richardson-Vicks Inc. | Antitussive liquid compositions containing phenol |
| IL90245A (en) * | 1988-05-11 | 1994-04-12 | Glaxo Group Ltd | Resin adsorbate comprising ranitidine together with a synthetic cation exchange resin, its preparation and pharmaceutical compositions containing it |
| US5219563A (en) * | 1988-05-11 | 1993-06-15 | Glaxo Group Limited | Drug adsorbates |
| IT1226800B (it) * | 1988-09-16 | 1991-02-19 | Prodotti Formenti | Composizioni farmaceutiche orali contenenti sali di destrorfano. |
| US4996047A (en) * | 1988-11-02 | 1991-02-26 | Richardson-Vicks, Inc. | Sustained release drug-resin complexes |
| CA2002492A1 (en) * | 1988-11-11 | 1990-05-11 | Sandra T. A. Malkowska | Pharmaceutical ion exchange resin composition |
| US5840293A (en) * | 1988-11-16 | 1998-11-24 | Advanced Polymer Systems, Inc. | Ionic beads for controlled release and adsorption |
| GB9005498D0 (en) * | 1990-03-12 | 1990-05-09 | Beecham Group Plc | Composition |
| DE69114006T2 (de) * | 1990-06-20 | 1996-05-02 | Advanced Polymer Systems Inc | Zusammensetzungen und verfahren für die kontrollierte freisetzung von löslichen wirkstoffen. |
| USRE39300E1 (en) | 1993-01-28 | 2006-09-19 | Virginia Commonwealth University Medical College Of Virginia | Inhibiting the development of tolerance to and/or dependence on an addictive substance |
| US5321012A (en) * | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| CA2128296A1 (en) * | 1993-12-22 | 1995-06-23 | Peter John Degen | Polyvinylidene fluoride membrane |
| US5931809A (en) | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
| EP0946145B1 (en) * | 1996-12-20 | 2008-09-03 | McNeil-PPC, Inc. | Antitussive drugs delivered by ion exchange resins |
| US5980882A (en) * | 1997-04-16 | 1999-11-09 | Medeva Pharmaceuticals Manufacturing | Drug-resin complexes stabilized by chelating agents |
| DE60040540D1 (de) * | 1999-07-14 | 2008-11-27 | Schering Plough Ltd | Maskieren des geschmacks der oralen flüssigen chinolon-zubereitungen mit ionenaustauscherharzen |
| US6514492B1 (en) | 1999-07-14 | 2003-02-04 | Schering-Plough Veterinary Corporation | Taste masking of oral quinolone liquid preparations using ion exchange resins |
| US7067116B1 (en) * | 2000-03-23 | 2006-06-27 | Warner-Lambert Company Llc | Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1 |
| ATE318299T1 (de) * | 2000-06-09 | 2006-03-15 | Procter & Gamble | Verfahren zur behandlung von gewebe mit einem waschmittelformkörper enthaltend ein ionenaustauscherharz |
| US6855721B1 (en) | 2000-07-28 | 2005-02-15 | Indevus Pharmaceuticals, Inc. | Methods and compositions for alleviating stuttering |
| EP1429728A1 (en) * | 2001-08-29 | 2004-06-23 | SRL Technologies, Inc. | Sustained release preparations |
| US20030060422A1 (en) | 2001-08-31 | 2003-03-27 | Balaji Venkataraman | Tannate compositions and methods of treatment |
| US20030180249A1 (en) * | 2002-03-18 | 2003-09-25 | Khanna Satish Chandra | Dosage forms for hygroscopic active ingredients |
| US8906413B2 (en) | 2003-05-12 | 2014-12-09 | Supernus Pharmaceuticals, Inc. | Drug formulations having reduced abuse potential |
| US20050142097A1 (en) * | 2003-12-29 | 2005-06-30 | Deepak Thassu | Multiple active drug resin conjugate |
| US20050238695A1 (en) * | 2004-04-27 | 2005-10-27 | Atma Chaudhari | Lozenge for delivery of dextromethorphan |
| MXPA06012564A (es) * | 2004-04-27 | 2007-01-31 | Medicinova Inc | Derivados de acido fenoxialquilcarboxilico en el tratamiento de enfermedades inflamatorias. |
| JP4805256B2 (ja) * | 2004-05-14 | 2011-11-02 | グリーン・クロス・コーポレイション | 右旋性モルヒナンの神経保護特性 |
| US20050265955A1 (en) * | 2004-05-28 | 2005-12-01 | Mallinckrodt Inc. | Sustained release preparations |
| ES2531735T3 (es) * | 2004-10-15 | 2015-03-18 | Supernus Pharmaceuticals, Inc. | Preparaciones farmacéuticas con menor potencial de abuso |
| JP2008546835A (ja) * | 2005-06-28 | 2008-12-25 | ユ セ ベ ソシエテ アノニム | 複数の活性薬物−樹脂抱合体 |
| US20080226579A1 (en) * | 2005-09-21 | 2008-09-18 | Chong Kun Dang Pharmaceutical Corp. | Novel Resinate Complex of S-Clopidogrel and Production Method Thereof |
| US20070286903A1 (en) * | 2006-06-13 | 2007-12-13 | Becicka Brian T | Composition and method for taste masking |
| SI2124556T1 (sl) | 2006-10-09 | 2015-01-30 | Charleston Laboratories, Inc. | Farmacevtske sestave |
| KR20090088913A (ko) | 2006-11-21 | 2009-08-20 | 맥네일-피피씨, 인코포레이티드 | 개질된 방출형 진통 현탁제 |
| US9833510B2 (en) | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
| EP3090743A1 (en) | 2008-01-09 | 2016-11-09 | Charleston Laboratories, Inc. | Pharmaceutical compositions for treating headache and eliminating nausea |
| US20100273822A1 (en) * | 2009-04-22 | 2010-10-28 | William Wayne Howard | Immediate release compositions and methods for delivering drug formulations using strong acid ion exchange resins |
| CA2767576C (en) | 2009-07-08 | 2020-03-10 | Charleston Laboratories Inc. | Pharmaceutical compositions comprising an antiemetic and an opioid analgesic |
| CN102138915A (zh) * | 2011-03-28 | 2011-08-03 | 于晓勇 | 一种口服药物制剂及其制备方法 |
| WO2013070656A1 (en) * | 2011-11-07 | 2013-05-16 | Navinta Llc | Sustained release suspension preparation for dextromethorphan |
| US8962687B2 (en) | 2012-12-05 | 2015-02-24 | Medicinova, Inc. | Method of treating liver disorders |
| US8835499B2 (en) | 2011-12-08 | 2014-09-16 | Medicinova, Inc. | Method of treating non-alcoholic fatty liver disease and steatohepatitis |
| BR112016001400B1 (pt) | 2013-07-25 | 2023-02-28 | Medicinova, Inc | Uso de ácidos fenoxialquilcarboxílicos para preparação de medicamentos para a redução de níveis sanguíneos de triglicerídeos, colesterol total e lipoproteínas de baixa densidade |
| US9346754B2 (en) | 2014-05-08 | 2016-05-24 | Medicinova, Inc. | Method of treating advanced non-alcoholic steatohepatitis |
| US20150321989A1 (en) | 2014-05-08 | 2015-11-12 | Medicinova, Inc. | Method of treating idiopathic pulmonary fibrosis |
| JP6469727B2 (ja) | 2014-06-02 | 2019-02-13 | メディシノバ・インコーポレイテッドＭｅｄｉｃｉＮｏｖａ， Ｉｎｃ． | 線維症の抑制又は治療方法 |
| KR102462638B1 (ko) | 2014-11-26 | 2022-11-03 | 메디시노바, 인크. | 이부딜라스트와 릴루졸의 배합물 및 이의 사용방법 |
| US11103499B2 (en) | 2016-08-26 | 2021-08-31 | EXCIVA (UG) (haftungsbeschränkt) | Compositions and methods thereof |
| US10745540B2 (en) * | 2017-08-01 | 2020-08-18 | Carefusion 2200, Inc. | Protection and selective release of colorant |
| CA3217719A1 (en) | 2021-05-28 | 2022-12-01 | Kazuko Matsuda | Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1413851A (fr) * | 1957-05-06 | 1965-10-15 | Clinical Products Ltd | Procédé de fabrication de composés destinés à dégager lentement et uniformément une substance active dans un milieu soit acide, soit basique |
| US2990332A (en) * | 1958-04-02 | 1961-06-27 | Wallace & Tiernan Inc | Pharmaceutical preparations comprising cation exchange resin adsorption compounds and treatment therewith |
| US3085942A (en) * | 1960-12-28 | 1963-04-16 | Hoffmann La Roche | Antitussive compositions and preparation |
| GB1220818A (en) * | 1967-10-31 | 1971-01-27 | Mar Pha Soc D Etude Et D Expl | New medicinal composition |
| GB1348642A (en) * | 1970-10-15 | 1974-03-20 | Howard A N | Hypocholesterolaemic compositions |
| US4221778A (en) * | 1979-01-08 | 1980-09-09 | Pennwalt Corporation | Prolonged release pharmaceutical preparations |
| US4427681A (en) * | 1982-09-16 | 1984-01-24 | Richardson-Vicks, Inc. | Thixotropic compositions easily convertible to pourable liquids |
| US4694010A (en) * | 1985-08-16 | 1987-09-15 | New York University | Anticonvulsant compositions and method |
-
1985
- 1985-12-09 US US06/806,879 patent/US4788055A/en not_active Expired - Lifetime
-
1986
- 1986-12-05 FI FI864975A patent/FI87525C/fi not_active IP Right Cessation
- 1986-12-05 PT PT83877A patent/PT83877B/pt not_active IP Right Cessation
- 1986-12-05 JP JP61289068A patent/JPS62138428A/ja active Pending
- 1986-12-05 EP EP86116914A patent/EP0225615A3/en not_active Withdrawn
- 1986-12-08 DK DK589086A patent/DK160601C/da not_active IP Right Cessation
- 1986-12-08 NO NO864918A patent/NO864918L/no unknown
- 1986-12-08 ZA ZA869255A patent/ZA869255B/xx unknown
- 1986-12-08 AU AU66181/86A patent/AU597316B2/en not_active Ceased
- 1986-12-08 IE IE863209A patent/IE863209L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO864918D0 (no) | 1986-12-08 |
| ZA869255B (en) | 1987-07-29 |
| AU597316B2 (en) | 1990-05-31 |
| NO864918L (no) | 1987-06-10 |
| EP0225615A2 (en) | 1987-06-16 |
| DK160601B (da) | 1991-04-02 |
| IE863209L (en) | 1987-06-09 |
| US4788055A (en) | 1988-11-29 |
| FI864975A0 (fi) | 1986-12-05 |
| FI864975L (fi) | 1987-06-10 |
| JPS62138428A (ja) | 1987-06-22 |
| PT83877B (pt) | 1989-06-30 |
| FI87525B (fi) | 1992-10-15 |
| EP0225615A3 (en) | 1988-04-20 |
| PT83877A (en) | 1987-01-01 |
| FI87525C (fi) | 1993-01-25 |
| AU6618186A (en) | 1987-06-11 |
| DK589086A (da) | 1987-06-10 |
| DK589086D0 (da) | 1986-12-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK160601C (da) | Farmaceutisk harpiksholdigt, sustained release praeparat med kontrolleret afgivelse af et farmaceutisk acceptabelt syreadditionssalt af dextromethorphan samt fremgangsmaade til fremstilling deraf | |
| DK708088A (da) | Farmaceutisk praeparat med forlaenget frigivelsestid | |
| DK287687D0 (da) | Nyt laegemiddelpraeparat med kontrolleret frigivelse af den virksomme forbindelse, fremgangsmaade til fremstilling deraf og anvendelse af det nye praeparat | |
| FI885460L (fi) | Menetelmä suun kautta annettavaksi tarkoitetun, aktiiviyhdistettä kontrolloidusti vapauttavan farmaseuttisen formulaation valmistamiseksi | |
| DK253988D0 (da) | Farmaceutisk praeparat med indhold af eperison eller tolperison, eller et salt deraf, til indgivelse gennem huden | |
| EP0193415A3 (en) | Spiro-3-heteroazolidine compounds and salts thereof, their preparation and pharmaceutical agents thereof | |
| DK52388A (da) | Polyaminderivater samt fremgangsmaader til deres fremstilling | |
| DK161365C (da) | Flydende farmaceutisk praeparat til oral indgivelse med kontrolleret frigivelse og god stabilitet, samt fremgangsmaade til fremstilling heraf | |
| DK266486D0 (da) | Quinoloncarboxylsyreestere eller farmaceutisk anvendelige hydratereller syreadditionssalte deraf, deres fremstilling og anvendelse | |
| DK112287D0 (da) | Anvendelse af 2-alkoxy-n-(1-azabicyclo-oe2,2,2aaoct-3-yl)-benzamider og -thiobenzamider samt farmaceutisk acceptable syreadditionssalte deraf som laegemidler | |
| DK645788D0 (da) | Anvendelse af ergolinderivater til fremstilling af et farmaceutisk praeparat | |
| DK455886A (da) | Imidazolinderivater, fremgangsmaade til deres fremstilling og midlerindeholdende disser forbindelser med herbicid virkning | |
| DK507986D0 (da) | Thieno-isoxazoler eller -pyrazoler og farmaceutisk acceptable syreadditionssalte deraf, fremgangsmaade og mellemprodukt til deres fremstilling samt deres anvendelse som antihypertensive midler | |
| GR890100726A (en) | Method for the preparation of a pharmaceutical solution comprising salbutamol and chromoglycic acid of salts thereof | |
| DK240989A (da) | 2-halogen-4,5-difluorbenzoesyre-forbindelser og fremgangsmaader til fremstilling deraf samt fremgangsmaade til fremstilling af 1-cyclopropyl-6,7-difluor-1,4-dihydro-4-oxo-quinolin-3-carboxylsyreestere | |
| IL90596A0 (en) | Skin penetration system for salts of amine-functional drugs | |
| DK287487D0 (da) | 4-phenyl-4-oxo-2-butensyrederivater, deres fremstilling samt laegemidler med indhold deraf | |
| DK44487D0 (da) | 1-oe3-(2-hydroxy-3-alkylaminopropoxy)-2-thienylaa-3-phenyl-1-propanon eller syreadditionssalt deraf samt fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse | |
| DK679788A (da) | 4-heteroaryl-1,3-benzodiazepiner og 2-substituerede alfa-(heteroaryl)-benzenethanaminer og farmaceutisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse | |
| DK504386A (da) | Gonadoliberinanaloge og farmaceutisk acceptable syreadditionssalte, deres fremstilling og anvendelse | |
| DK454588D0 (da) | Substituerede thienoimidazolderivater, deres fremstilling, farmaceutiske praeparater deraf og deres anvendelse som mavesyresekretionshaemmende midler | |
| DK418589D0 (da) | Anvendelse af pyrazolopyridinderivater eller fysiologiske acceptable salt deraf til laegemiddelfremstilling | |
| DK160827C (da) | Pteridinderivater, fremgangsmaade til fremstilling heraf samt farmaceutisk praeparat | |
| DK560689A (da) | Langsomt frigoerende farmaceutisk praeparat fremstillet med alginsyre | |
| NO872354L (no) | Nytt legemiddelpreparat med kontrollert frigivelse av den aktive forbindelsen, en fremgangsmaate for fremstilling derav og anvendelse av det nye preparatet. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |