DK160806C - Stabil, vandig syreoploesning af cis-platin egnet til injektion og fremgangsmaade til fremstilling heraf - Google Patents

Stabil, vandig syreoploesning af cis-platin egnet til injektion og fremgangsmaade til fremstilling heraf

Info

Publication number: DK160806C
Authority: DK; Denmark
Prior art keywords: injection; stable; procedures; producing; acid solution
Prior art date: 1983-10-24

Application number

DK504384A

Other languages

Danish (da)

English (en)

Other versions

DK160806B (da

DK504384A (da

DK504384D0 (da

Inventor

Alfred James Nijkerk

Original Assignee

Pharmachemie Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-10-24

Filing date

1984-10-23

Publication date

1991-10-07

1984-10-23 Application filed by Pharmachemie Bv filed Critical Pharmachemie Bv

1984-10-23 Publication of DK504384D0 publication Critical patent/DK504384D0/da

1985-04-25 Publication of DK504384A publication Critical patent/DK504384A/da

1991-04-22 Publication of DK160806B publication Critical patent/DK160806B/da

1991-10-07 Application granted granted Critical

1991-10-07 Publication of DK160806C publication Critical patent/DK160806C/da

Links

239000000243 solution Substances 0.000 title abstract 6
238000002347 injection Methods 0.000 title abstract 2
239000007924 injection Substances 0.000 title abstract 2
239000011260 aqueous acid Substances 0.000 title 1
DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 title 1
229960004316 cisplatin Drugs 0.000 title 1
238000000034 method Methods 0.000 title 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 4
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
229910052697 platinum Inorganic materials 0.000 abstract 3
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 3
239000011780 sodium chloride Substances 0.000 abstract 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
239000004615 ingredient Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Inorganic Chemistry (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Excavating Of Shafts Or Tunnels (AREA)
Escalators And Moving Walkways (AREA)
Hydraulic Clutches, Magnetic Clutches, Fluid Clutches, And Fluid Joints (AREA)
Catalysts (AREA)

DK504384A 1983-10-24 1984-10-23 Stabil, vandig syreoploesning af cis-platin egnet til injektion og fremgangsmaade til fremstilling heraf DK160806C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL8303657A NL8303657A (nl)	1983-10-24	1983-10-24	Voor injectie geschikte, stabiele, waterige, zoutzuur bevattende oplossing van cisplatine, alsmede werkwijze ter bereiding daarvan.
NL8303657		1983-10-24

Publications (4)

Publication Number	Publication Date
DK504384D0 DK504384D0 (da)	1984-10-23
DK504384A DK504384A (da)	1985-04-25
DK160806B DK160806B (da)	1991-04-22
DK160806C true DK160806C (da)	1991-10-07

Family

ID=19842603

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK504384A DK160806C (da)	1983-10-24	1984-10-23	Stabil, vandig syreoploesning af cis-platin egnet til injektion og fremgangsmaade til fremstilling heraf

Country Status (11)

Country	Link
EP (1)	EP0143478B1 (de)
JP (1)	JPS60172923A (de)
AT (1)	ATE28402T1 (de)
AU (1)	AU576204B2 (de)
DE (1)	DE3464849D1 (de)
DK (1)	DK160806C (de)
ES (1)	ES9300011A1 (de)
FI (1)	FI78837C (de)
IL (1)	IL72829A (de)
NL (1)	NL8303657A (de)
NO (1)	NO165277C (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL83380A (en) *	1987-07-30	1991-04-15	Teva Pharma	Stable aqueous cisplatin solutions
NL8901433A (nl) *	1989-06-06	1991-01-02	Pharmachemie Bv	Carboplatinpreparaat.
WO1994005299A1 (fr) *	1992-09-04	1994-03-17	Fuji Kagaku Kogyo Kabushiki Kaisha	Compositions medicinales
US6861422B2 (en)	2003-02-26	2005-03-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
DE102004029784A1 (de)	2004-06-21	2006-01-05	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
DE102004033670A1 (de)	2004-07-09	2006-02-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
US7759485B2 (en)	2004-08-14	2010-07-20	Boehringer Ingelheim International Gmbh	Process for the manufacture of dihydropteridinones
US20060074088A1 (en)	2004-08-14	2006-04-06	Boehringer Ingelheim International Gmbh	Dihydropteridinones for the treatment of cancer diseases
US20060058311A1 (en)	2004-08-14	2006-03-16	Boehringer Ingelheim International Gmbh	Combinations for the treatment of diseases involving cell proliferation
US7728134B2 (en)	2004-08-14	2010-06-01	Boehringer Ingelheim International Gmbh	Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US20060035903A1 (en)	2004-08-14	2006-02-16	Boehringer Ingelheim International Gmbh	Storage stable perfusion solution for dihydropteridinones
EP1630163A1 (de)	2004-08-25	2006-03-01	Boehringer Ingelheim Pharma GmbH & Co.KG	Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004058337A1 (de)	2004-12-02	2006-06-14	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
US7439358B2 (en)	2006-02-08	2008-10-21	Boehringer Ingelheim International Gmbh	Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
EP2185559A1 (de)	2007-08-03	2010-05-19	Boehringer Ingelheim International GmbH	Kristalline form eines dihydropteridionderivats
US9358233B2 (en)	2010-11-29	2016-06-07	Boehringer Ingelheim International Gmbh	Method for treating acute myeloid leukemia
US9370535B2 (en)	2011-05-17	2016-06-21	Boehringer Ingelheim International Gmbh	Method for treatment of advanced solid tumors
US20150031699A1 (en)	2013-07-26	2015-01-29	Boehringer Ingelheim International Gmbh	Treatment of myelodysplastic syndrome
US9867831B2 (en)	2014-10-01	2018-01-16	Boehringer Ingelheim International Gmbh	Combination treatment of acute myeloid leukemia and myelodysplastic syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4310515A (en) *	1978-05-30	1982-01-12	Bristol-Myers Company	Pharmaceutical compositions of cisplatin
CA1119954A (en) *	1978-05-30	1982-03-16	Edmund S. Granatek	Aqueous solution of cisplatin
US4302446A (en) *	1979-10-02	1981-11-24	Bristol-Myers Company	Pharmaceutical compositions
AU541056B2 (en) *	1980-03-31	1984-12-13	Bristol-Myers Company	Pharmaceuticals formulations
US4426372A (en) *	1980-08-08	1984-01-17	Regents Of The University Of Minnesota	Inhibition of undesired effects of platinum(II) compounds
IT1153974B (it) *	1982-09-23	1987-01-21	Erba Farmitalia	Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento

1983
- 1983-10-24 NL NL8303657A patent/NL8303657A/nl not_active Application Discontinuation
1984
- 1984-08-20 FI FI843286A patent/FI78837C/fi not_active IP Right Cessation
- 1984-08-22 AU AU32269/84A patent/AU576204B2/en not_active Expired
- 1984-08-31 IL IL72829A patent/IL72829A/xx not_active IP Right Cessation
- 1984-10-04 AT AT84201425T patent/ATE28402T1/de not_active IP Right Cessation
- 1984-10-04 EP EP84201425A patent/EP0143478B1/de not_active Expired
- 1984-10-04 DE DE8484201425T patent/DE3464849D1/de not_active Expired
- 1984-10-22 JP JP59222864A patent/JPS60172923A/ja active Pending
- 1984-10-23 DK DK504384A patent/DK160806C/da not_active IP Right Cessation
- 1984-10-23 NO NO844225A patent/NO165277C/no not_active IP Right Cessation
- 1984-10-24 ES ES537033A patent/ES9300011A1/es active Pending

Also Published As

Publication number	Publication date
ATE28402T1 (de)	1987-08-15
EP0143478B1 (de)	1987-07-22
DE3464849D1 (en)	1987-08-27
JPS60172923A (ja)	1985-09-06
FI843286L (fi)	1985-04-25
EP0143478A1 (de)	1985-06-05
IL72829A0 (en)	1984-11-30
AU576204B2 (en)	1988-08-18
FI78837C (fi)	1989-10-10
NO165277C (no)	1991-01-30
DK160806B (da)	1991-04-22
FI843286A0 (fi)	1984-08-20
NO165277B (no)	1990-10-15
DK504384A (da)	1985-04-25
IL72829A (en)	1986-09-30
DK504384D0 (da)	1984-10-23
NL8303657A (nl)	1985-05-17
NO844225L (no)	1985-04-25
FI78837B (fi)	1989-06-30
AU3226984A (en)	1985-06-13
ES9300011A1 (es)	1993-10-16

Legal Events

Date	Code	Title	Description
2004-11-15	PUP	Patent expired

Publication	Publication Date	Title
DK160806C (da)	1991-10-07	Stabil, vandig syreoploesning af cis-platin egnet til injektion og fremgangsmaade til fremstilling heraf
ES2004931A6 (es)	1989-02-16	Un procedimiento para preparar un concentrado transparente y estable frente al almacenamiento y un procedimiento para fabricar un desinfectante
AU4944885A (en)	1986-05-15	Biooxidising subterranean water using hydrogen peroxide
ZA200005696B (en)	2002-01-28	Stable concentrated rare earth carboxylate liquids.
ATE198400T1 (de)	2001-01-15	Biozide zusammensetzung
BG43863A3 (bg)	1988-08-15	Метод за получаване на оптически активен карнитиннитрил хлорид
ATE15853T1 (de)	1985-10-15	Methode zur herstellung eines gelierten nahrungsmittels.
HUT54053A (en)	1991-01-28	Process for producing stabile aquous solution of 8-n-(diethyl-amino-ethyl)-rebeccamycin
MY104814A (en)	1994-04-30	Improvements in or relating to dobutamine salts
SU544612A1 (ru)	1977-01-30	Способ очистки рассола
KR920009689A (ko)	1992-06-25	안정화 이산화염소 수용액의 제조방법
SU1744946A1 (ru)	1998-11-10	Способ получения смеси изомеров 9-(2-хлорэтил)-7-нитрозо-l-гомоцитруллина и 9-(2-хлорэтил)-9-нитрозо-l-гомоцитруллина
FR2354714A1 (fr)	1978-01-13	Complement alimentaire contenant du fer destine a des porcelets et son application
JPS5582128A (en)	1980-06-20	Preparation of making film containing enzyme
ES468322A1 (es)	1979-09-16	Procedimiento para la preparacion de un derivado del benci- clan
ATE82269T1 (de)	1992-11-15	Verfahren zur herstellung von 1-pyrazolinen.
KR920003880A (ko)	1992-03-27	조미용 액체소금 및 그 제조방법
KR870003009A (ko)	1987-04-14	수성 클로로옥사이드-용액의 제조방법
KR960004365A (ko)	1996-02-23	5'-리보뉴클레오티드칼슘의 제조방법
SU917484A1 (ru)	1999-12-27	Способ получения хлорнокислых солей магния или кальция