DK1622648T3 - DNA-vacciner mod tumorvækst og fremgangsmåder til anvendelse deraf - Google Patents
DNA-vacciner mod tumorvækst og fremgangsmåder til anvendelse derafInfo
- Publication number
- DK1622648T3 DK1622648T3 DK04749425.7T DK04749425T DK1622648T3 DK 1622648 T3 DK1622648 T3 DK 1622648T3 DK 04749425 T DK04749425 T DK 04749425T DK 1622648 T3 DK1622648 T3 DK 1622648T3
- Authority
- DK
- Denmark
- Prior art keywords
- human
- protein
- tumor growth
- cancer
- apoptosis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001136—Cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001148—Regulators of development
- A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45700903P | 2003-03-24 | 2003-03-24 | |
| PCT/US2004/008932 WO2004099389A2 (en) | 2003-03-24 | 2004-03-24 | Dna vaccines against tumor growth and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1622648T3 true DK1622648T3 (da) | 2010-09-06 |
Family
ID=33434911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04749425.7T DK1622648T3 (da) | 2003-03-24 | 2004-03-24 | DNA-vacciner mod tumorvækst og fremgangsmåder til anvendelse deraf |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8716254B2 (da) |
| EP (1) | EP1622648B1 (da) |
| JP (1) | JP4616827B2 (da) |
| KR (1) | KR101199789B1 (da) |
| CN (1) | CN1791433B (da) |
| AT (1) | ATE472339T1 (da) |
| AU (1) | AU2004236636B2 (da) |
| BR (1) | BRPI0408774A (da) |
| CA (1) | CA2519953C (da) |
| DE (1) | DE602004027902D1 (da) |
| DK (1) | DK1622648T3 (da) |
| ES (1) | ES2345200T3 (da) |
| MX (1) | MXPA05010255A (da) |
| PL (1) | PL1622648T3 (da) |
| PT (1) | PT1622648E (da) |
| RU (1) | RU2343195C2 (da) |
| WO (1) | WO2004099389A2 (da) |
| ZA (1) | ZA200508579B (da) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005294805B2 (en) | 2004-05-28 | 2012-02-16 | Oryxe | A mixture for transdermal delivery of low and high molecular weight compounds |
| US20060276423A1 (en) * | 2005-04-18 | 2006-12-07 | Rachel Altura | Survivin-directed RNA interference-compositions and methods |
| US20070104689A1 (en) * | 2005-09-27 | 2007-05-10 | Merck Patent Gmbh | Compositions and methods for treating tumors presenting survivin antigens |
| KR100790377B1 (ko) * | 2006-02-15 | 2008-01-02 | 고려대학교 산학협력단 | 인터페론감마를 발현하는 살모넬라 균주를 함유하는항바이러스용 조성물 |
| PL2035581T3 (pl) * | 2006-06-21 | 2013-01-31 | Scripps Research Inst | Kompozycja DNA przeciwko FAP - antygenowi zrębowemu nowotworu i sposoby jej stosowania |
| CA2656700A1 (en) * | 2006-07-06 | 2008-01-10 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Compositions and methods for enhancing the efficacy of il-2 mediated immune responses |
| FR2903605A1 (fr) * | 2006-07-12 | 2008-01-18 | Sanofi Pasteur Sa | Methode d'immunisation contre les quatres serotypes de la dengue |
| FR2906724B1 (fr) * | 2006-10-04 | 2009-03-20 | Sanofi Pasteur Sa | Methode d'immunisation contre les 4 serotypes de la dengue. |
| WO2008067305A2 (en) * | 2006-11-28 | 2008-06-05 | Giic Research Development Corporation | Polypeptides comprising intracytoplasmic death domain and nkg2d ligand domain |
| FR2909286B1 (fr) * | 2006-12-01 | 2012-06-08 | Sanofi Pasteur | Methode d'immunisation contre les 4 serotypes de la dengue |
| CN101981187A (zh) | 2008-03-31 | 2011-02-23 | 株式会社生物免疫平衡 | MHC Ⅱ类分子提呈的存活蛋白(Survivin)的部分肽及其利用方法 |
| EP2411503B1 (en) * | 2009-03-27 | 2017-09-13 | Eidgenössische Technische Hochschule Zürich | Salmonella enterica presenting c. jejuni n-glycan or derivatives thereof |
| RU2431669C2 (ru) * | 2009-06-23 | 2011-10-20 | Государственное образовательное учреждение высшего профессионального образования "Казанский государственный университет им. В.И. Ульянова-Ленина" | Способ получения лекарственного препарата генетически модифицированных клеток |
| CA2769409A1 (en) * | 2009-08-17 | 2011-02-24 | The Penn State Research Foundation | Use of nkg2d inhibitors for treating cardiovascular and metabolic diseases, such as type 2 diabetes |
| KR101815322B1 (ko) * | 2010-01-12 | 2018-01-05 | 서울대학교산학협력단 | 항암 펩타이드 서열 |
| CN102985109B (zh) * | 2010-06-25 | 2016-05-11 | 瓦西博迪公司 | 同型二聚体蛋白质构建体 |
| CN102210862B (zh) * | 2011-06-01 | 2013-06-12 | 中国人民解放军南京军区福州总医院 | 基于Livin的免疫刺激复合物及其制备方法和应用 |
| PT2961831T (pt) * | 2013-02-26 | 2020-10-12 | Memorial Sloan Kettering Cancer Center | Composições e métodos para imunoterapêutica |
| AU2014228405B2 (en) * | 2013-03-15 | 2017-05-11 | The Trustees Of The University Of Pennsylvania | Cancer vaccines and methods of treatment using the same |
| US20160058856A1 (en) * | 2013-04-05 | 2016-03-03 | Kyushu University, National University Corporation | Anti-tumor dna vaccine |
| US20160176943A1 (en) * | 2013-07-05 | 2016-06-23 | Inserm (Insititut National De La Sante Et De La Recherche Medicale) | Novel alternative splice transcripts for mhc class i related chain alpha (mica) and uses thereof |
| WO2015139020A2 (en) * | 2014-03-14 | 2015-09-17 | Dana-Farber Cancer Institute, Inc. | Vaccine compositions and methods for restoring nkg2d pathway function against cancers |
| AU2015308695B2 (en) * | 2014-08-29 | 2020-11-05 | The Regents Of The University Of California | Vaccine for livestock production systems |
| WO2016179573A1 (en) | 2015-05-07 | 2016-11-10 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Variant survivin vaccine for treatment of cancer |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| KR20180053318A (ko) | 2015-09-17 | 2018-05-21 | 제이알엑스 바이오테크놀로지, 인코포레이티드 | 피부 수화 또는 보습을 향상시키기 위한 접근법 |
| PL3356413T3 (pl) | 2015-10-01 | 2022-04-19 | Potenza Therapeutics, Inc. | Białka anty-tigit wiążące antygen oraz sposoby ich zastosowania |
| WO2018147801A1 (en) * | 2017-02-07 | 2018-08-16 | Agency For Science, Technology And Research | Methods and kits for generating mimetic innate immune cells from pluripotent stem cells |
| JOP20190203A1 (ar) | 2017-03-30 | 2019-09-03 | Potenza Therapeutics Inc | بروتينات رابطة لمولد ضد مضادة لـ tigit وطرق استخدامها |
| CN110448689A (zh) * | 2019-08-06 | 2019-11-15 | 太仓美诺恒康生物技术有限公司 | mRNA疫苗及其试剂盒、应用 |
| US20230143947A1 (en) * | 2019-09-20 | 2023-05-11 | Crage Medical Co., Limited | Immune effector cell in which expression is regulated by cytokines |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
| WO2022152939A1 (en) | 2021-01-18 | 2022-07-21 | Conserv Bioscience Limited | Coronavirus immunogenic compositions, methods and uses thereof |
| RU2770490C1 (ru) * | 2021-07-14 | 2022-04-18 | Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" | Рекомбинантная плазмидная ДНК pET19b-Surv-OL, обеспечивающая синтез гибридного белка сурвивин-обелин (Surv-OL) и гибридный белок, связываемый анти-сурвивин антителами и обладающий биолюминесцентной активностью |
| CN116077534B (zh) * | 2023-01-31 | 2024-08-27 | 大连工业大学 | 一种凝结芽孢杆菌的应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3993223A (en) * | 1974-07-25 | 1976-11-23 | American Home Products Corporation | Dispensing container |
| GB9104596D0 (en) * | 1991-03-05 | 1991-04-17 | Wellcome Found | Production of recombinant proteins |
| US5702917A (en) * | 1992-01-27 | 1997-12-30 | Icos Corporation | Polynucleotides encoding human ICAM-4 |
| RU2077340C1 (ru) * | 1993-08-06 | 1997-04-20 | Всероссийский научно-исследовательский институт ветеринарной вирусологии и микробиологии | Способ получения специфической сыворотки для лечения, диагностики и профилактики вирусной геморрагической болезни кроликов и набор для диагностики болезни |
| US5733760A (en) * | 1994-08-05 | 1998-03-31 | Virus Research Institute | Salmonella vectors encoding truncated pag fusion protein, method of making, and uses thereof |
| US6190657B1 (en) * | 1995-06-07 | 2001-02-20 | Yale University | Vectors for the diagnosis and treatment of solid tumors including melanoma |
| RU2219942C2 (ru) * | 1996-02-24 | 2003-12-27 | Берингер Ингельхайм Интернациональ Гмбх | Лекарственный состав с иммуномодуляторным действием, содержащий пептиды и вспомогательные средства |
| US6245523B1 (en) * | 1996-11-20 | 2001-06-12 | Yale University | Survivin, a protein that inhibits cellular apoptosis, and its modulation |
| EP1015035B1 (en) * | 1997-08-13 | 2009-01-28 | The Uab Research Foundation | Vaccination by topical application of genetic vectors |
| AU742757C (en) * | 1997-12-17 | 2007-05-17 | Immunex Corporation | Cell surface glycoproteins associated with human B cell lymphomas - ULBP, DNA and polypeptides |
| US20030215803A1 (en) * | 2000-12-07 | 2003-11-20 | Garcia Pablo Dominguez | Human genes and gene expression products isolated from human prostate |
| WO2000003693A1 (en) * | 1998-07-14 | 2000-01-27 | Jenner Biotherapies, Inc. | Survivin, and peptides thereof, as an anti-cancer vaccine |
| US6472172B1 (en) * | 1998-07-31 | 2002-10-29 | Schering Aktiengesellschaft | DNA encoding a novel human inhibitor-of-apoptosis protein |
| US6838283B2 (en) * | 1998-09-29 | 2005-01-04 | Isis Pharmaceuticals Inc. | Antisense modulation of survivin expression |
| US6335194B1 (en) * | 1998-09-29 | 2002-01-01 | Isis Pharmaceuticals, Inc. | Antisense modulation of survivin expression |
| IT1303683B1 (it) * | 1998-10-30 | 2001-02-23 | Menarini Ricerche Spa | Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica. |
| US6413768B1 (en) * | 1998-12-02 | 2002-07-02 | University Of Maryland | Expression plasmids |
| AU765160B2 (en) * | 1998-12-18 | 2003-09-11 | Symrise Gmbh & Co. Kg | Encapsulated flavour and/or fragrance preparations |
| AU2001273102A1 (en) * | 2000-06-29 | 2002-01-14 | The Salk Institute For Biological Studies | Crystal structure of survivin |
| EP1256354A1 (en) * | 2001-05-11 | 2002-11-13 | Schering Corporation | Methods for treating cancer |
| AU2002326961A1 (en) * | 2001-10-10 | 2003-04-22 | Centocor, Inc. | Nucleic acid vaccines using tumor antigen encoding nucleic acids with cytokine adjuvant encoding nucleic acid |
| AU2003279770A1 (en) * | 2002-10-01 | 2004-04-23 | Novartis Vaccines And Diagnostics, Inc. | Anti-cancer and anti-infectious disease compositions and methods for using same |
| WO2004055050A2 (en) * | 2002-12-10 | 2004-07-01 | Endocube Sas | Thap proteins as nuclear receptors for chemokines and roles in transcriptional regulation, cell proliferation and cell differentiation |
-
2004
- 2004-03-24 DE DE602004027902T patent/DE602004027902D1/de not_active Expired - Lifetime
- 2004-03-24 AT AT04749425T patent/ATE472339T1/de active
- 2004-03-24 CN CN2004800135569A patent/CN1791433B/zh not_active Expired - Fee Related
- 2004-03-24 AU AU2004236636A patent/AU2004236636B2/en not_active Ceased
- 2004-03-24 WO PCT/US2004/008932 patent/WO2004099389A2/en not_active Ceased
- 2004-03-24 CA CA2519953A patent/CA2519953C/en not_active Expired - Fee Related
- 2004-03-24 DK DK04749425.7T patent/DK1622648T3/da active
- 2004-03-24 KR KR1020057017978A patent/KR101199789B1/ko not_active Expired - Fee Related
- 2004-03-24 US US10/807,897 patent/US8716254B2/en not_active Expired - Fee Related
- 2004-03-24 JP JP2006507511A patent/JP4616827B2/ja not_active Expired - Fee Related
- 2004-03-24 RU RU2005132578/13A patent/RU2343195C2/ru not_active IP Right Cessation
- 2004-03-24 EP EP04749425A patent/EP1622648B1/en not_active Expired - Lifetime
- 2004-03-24 MX MXPA05010255A patent/MXPA05010255A/es active IP Right Grant
- 2004-03-24 PL PL04749425T patent/PL1622648T3/pl unknown
- 2004-03-24 ES ES04749425T patent/ES2345200T3/es not_active Expired - Lifetime
- 2004-03-24 PT PT04749425T patent/PT1622648E/pt unknown
- 2004-03-24 BR BRPI0408774-7A patent/BRPI0408774A/pt not_active Application Discontinuation
-
2005
- 2005-10-21 ZA ZA200508579A patent/ZA200508579B/en unknown
-
2014
- 2014-05-05 US US14/269,998 patent/US9655815B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006523217A (ja) | 2006-10-12 |
| CA2519953A1 (en) | 2004-11-18 |
| DE602004027902D1 (de) | 2010-08-12 |
| EP1622648B1 (en) | 2010-06-30 |
| EP1622648A2 (en) | 2006-02-08 |
| US9655815B2 (en) | 2017-05-23 |
| EP1622648A4 (en) | 2007-02-14 |
| CN1791433B (zh) | 2010-05-26 |
| WO2004099389A2 (en) | 2004-11-18 |
| CN1791433A (zh) | 2006-06-21 |
| US20040192631A1 (en) | 2004-09-30 |
| WO2004099389A3 (en) | 2005-09-29 |
| ES2345200T3 (es) | 2010-09-17 |
| PT1622648E (pt) | 2010-08-31 |
| RU2005132578A (ru) | 2006-05-10 |
| BRPI0408774A (pt) | 2006-03-28 |
| ATE472339T1 (de) | 2010-07-15 |
| CA2519953C (en) | 2016-01-05 |
| KR101199789B1 (ko) | 2012-11-09 |
| US20140322249A1 (en) | 2014-10-30 |
| AU2004236636A1 (en) | 2004-11-18 |
| RU2343195C2 (ru) | 2009-01-10 |
| JP4616827B2 (ja) | 2011-01-19 |
| AU2004236636B2 (en) | 2010-02-04 |
| KR20050121694A (ko) | 2005-12-27 |
| US8716254B2 (en) | 2014-05-06 |
| MXPA05010255A (es) | 2005-12-14 |
| PL1622648T3 (pl) | 2010-11-30 |
| ZA200508579B (en) | 2007-04-25 |
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