DK162997C - Fremgangsmaade til fremstilling af 5,6,7,8-tetrahydrofolinsyre - Google Patents

Fremgangsmaade til fremstilling af 5,6,7,8-tetrahydrofolinsyre

Info

Publication number
DK162997C
DK162997C DK486985A DK486985A DK162997C DK 162997 C DK162997 C DK 162997C DK 486985 A DK486985 A DK 486985A DK 486985 A DK486985 A DK 486985A DK 162997 C DK162997 C DK 162997C
Authority
DK
Denmark
Prior art keywords
preparing
tetrahydropholic
acid
tetrahydropholic acid
Prior art date
Application number
DK486985A
Other languages
English (en)
Other versions
DK486985A (da
DK162997B (da
DK486985D0 (da
Inventor
Yutaka Hirai
Masaaki Torisu
Eri Nagayoshi
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59221189A external-priority patent/JPS61100583A/ja
Priority claimed from JP12513085A external-priority patent/JPH0631237B2/ja
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of DK486985D0 publication Critical patent/DK486985D0/da
Publication of DK486985A publication Critical patent/DK486985A/da
Publication of DK162997B publication Critical patent/DK162997B/da
Application granted granted Critical
Publication of DK162997C publication Critical patent/DK162997C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK486985A 1984-10-23 1985-10-23 Fremgangsmaade til fremstilling af 5,6,7,8-tetrahydrofolinsyre DK162997C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP59221189A JPS61100583A (ja) 1984-10-23 1984-10-23 5,6,7,8−テトラヒドロ葉酸の製造方法
JP22118984 1984-10-23
JP12513085A JPH0631237B2 (ja) 1985-06-11 1985-06-11 5,6,7,8−テトラヒドロ葉酸及びその誘導体の保存安定化方法
JP12513085 1985-06-11

Publications (4)

Publication Number Publication Date
DK486985D0 DK486985D0 (da) 1985-10-23
DK486985A DK486985A (da) 1986-04-24
DK162997B DK162997B (da) 1992-01-06
DK162997C true DK162997C (da) 1992-06-01

Family

ID=26461650

Family Applications (1)

Application Number Title Priority Date Filing Date
DK486985A DK162997C (da) 1984-10-23 1985-10-23 Fremgangsmaade til fremstilling af 5,6,7,8-tetrahydrofolinsyre

Country Status (8)

Country Link
US (1) US4665176A (da)
EP (1) EP0179654B1 (da)
KR (2) KR870001648B1 (da)
AU (1) AU556498B2 (da)
CA (1) CA1234570A (da)
DE (1) DE3578862D1 (da)
DK (1) DK162997C (da)
MX (1) MX166400B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8621268D0 (en) * 1986-09-03 1986-10-08 Univ Strathclyde Separation of substances
CH673459A5 (da) * 1987-05-15 1990-03-15 Eprova Ag
CH681303A5 (da) * 1991-01-16 1993-02-26 Eprova Ag
CH686369A5 (de) * 1994-05-09 1996-03-15 Eprova Ag Stabile kristalline (6S)- und (6R)-Tetrahydrofolseure.
US6162914A (en) * 1998-04-24 2000-12-19 Cerbios-Pharma S.A. Process for the reduction of pterins
CN1188414C (zh) 1998-10-14 2005-02-09 协和发酵工业株式会社 稳定吡唑并吖啶酮衍生物水溶液的方法
CN114181210B (zh) * 2021-12-01 2024-04-26 深圳奥萨制药有限公司 一种四氢叶酸的制备方法
CN120535525B (zh) * 2025-07-25 2025-10-14 化学与精细化工广东省实验室 一种Co/CeO2-Al2O3催化剂催化叶酸连续流加氢制备四氢叶酸的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2717250A (en) * 1950-04-29 1955-09-06 American Cyanamid Co Formylation of tetrahydro-10-formylpteroic acid and amino acid amides
US2790802A (en) * 1954-05-06 1957-04-30 American Cyanamid Co Substituted tetrahydropteridines and method of preparing the same
US3870719A (en) * 1972-06-16 1975-03-11 Us Health Synthesis of n-5-methyltetrahydrohomofolic acid and related reduced derivatives of homofolic acid
JPS5883691A (ja) * 1981-11-13 1983-05-19 Kanegafuchi Chem Ind Co Ltd 1′,2′−ジアシル−(6r,s)−5,6,7,8−テトラヒドロ−l−ビオプテリンおよびその製法
JPS60178887A (ja) * 1984-02-23 1985-09-12 Kanegafuchi Chem Ind Co Ltd 5,6,7,8−テトラヒドロ−l−ビオプテリンの製造法

Also Published As

Publication number Publication date
AU4854685A (en) 1986-05-01
DK486985A (da) 1986-04-24
CA1234570A (en) 1988-03-29
AU556498B2 (en) 1986-11-06
EP0179654B1 (en) 1990-07-25
KR870001648B1 (ko) 1987-09-18
MX166400B (es) 1993-01-07
EP0179654A2 (en) 1986-04-30
DE3578862D1 (de) 1990-08-30
DK162997B (da) 1992-01-06
KR860003253A (ko) 1986-05-21
US4665176A (en) 1987-05-12
KR880000092B1 (ko) 1988-02-23
DK486985D0 (da) 1985-10-23
EP0179654A3 (en) 1987-08-05

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PBP Patent lapsed