DK1638989T3 - Fremgangsmåde og apparat til kontinuerlig radiomærkning af proteiner i stor målestok - Google Patents

Fremgangsmåde og apparat til kontinuerlig radiomærkning af proteiner i stor målestok

Info

Publication number
DK1638989T3
DK1638989T3 DK04785799T DK04785799T DK1638989T3 DK 1638989 T3 DK1638989 T3 DK 1638989T3 DK 04785799 T DK04785799 T DK 04785799T DK 04785799 T DK04785799 T DK 04785799T DK 1638989 T3 DK1638989 T3 DK 1638989T3
Authority
DK
Denmark
Prior art keywords
radiolabelling
continuous
proteins
scale
scale proteins
Prior art date
Application number
DK04785799T
Other languages
English (en)
Inventor
Raimo Pellikka
Steven W King
Peter Blaeuenstein
Pius A Schubiger
Original Assignee
Peregrine Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peregrine Pharmaceuticals Inc filed Critical Peregrine Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1638989T3 publication Critical patent/DK1638989T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/496—Multiperforated metal article making
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK04785799T 2003-06-25 2004-06-25 Fremgangsmåde og apparat til kontinuerlig radiomærkning af proteiner i stor målestok DK1638989T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48238703P 2003-06-25 2003-06-25
US49312103P 2003-08-07 2003-08-07
US49368903P 2003-08-08 2003-08-08
PCT/US2004/020492 WO2005003151A2 (en) 2003-06-25 2004-06-25 Method and apparatus for continuous large-scale radiolabeling of proteins

Publications (1)

Publication Number Publication Date
DK1638989T3 true DK1638989T3 (da) 2008-11-17

Family

ID=33568598

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04785799T DK1638989T3 (da) 2003-06-25 2004-06-25 Fremgangsmåde og apparat til kontinuerlig radiomærkning af proteiner i stor målestok

Country Status (9)

Country Link
US (2) US7591953B2 (da)
EP (2) EP1964847A3 (da)
AT (1) ATE402947T1 (da)
AU (1) AU2004253924B2 (da)
CA (1) CA2527054C (da)
DE (1) DE602004015454D1 (da)
DK (1) DK1638989T3 (da)
NZ (1) NZ543495A (da)
WO (1) WO2005003151A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005003151A2 (en) * 2003-06-25 2005-01-13 Peregrine Pharmaceuticals, Inc. Method and apparatus for continuous large-scale radiolabeling of proteins
GB0520527D0 (en) * 2005-10-10 2005-11-16 Ge Healthcare Ltd Automated method
WO2009058737A1 (en) * 2007-10-29 2009-05-07 Pain Therapeutics, Inc. Disposable column system for purification of radiolabeled polypeptides
ITBO20080236A1 (it) * 2008-04-17 2009-10-18 Philogen Spa Apparecchiatura e metodo per la preparazione di medicinali contenenti sostanze radioattive.
US9540607B2 (en) * 2011-02-22 2017-01-10 Cytonet, Llc Fill system for providing uniform concentrations and volumes and methods thereof
WO2013053779A1 (en) * 2011-10-10 2013-04-18 DASGIP Information and Process Technology GmbH Biotechnological apparatus comprising a bioreactor, exhaust gas temperature control device for a bioreactor and a method for treating an exhaust gas stream in a biotechnological apparatus
DE102012209852A1 (de) 2012-06-12 2013-12-12 Robert Bosch Gmbh Abgasreinigungssystem zur Anordnung in einem Abgasstrang eines Kraftfahrzeuges, insbesondere eines Dieselkraftfahrzeugs
US20140329319A1 (en) * 2013-05-02 2014-11-06 Canadian Blood Services Apparatus and method for the immunocamouflage of biological cells
PL3157577T3 (pl) 2014-06-18 2021-04-19 Alpha Therapy Solutions Ab Automatyczna platforma technologii produkcji radiofarmaceutyków astatyna-211 [at-211]

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3816033A (en) * 1972-11-21 1974-06-11 Greiner Scient Corp Multi-channel pump
US4205050A (en) * 1976-06-17 1980-05-27 Chevron Research Company Method of reducing corrosion in sour gas sweetening systems
US4301139A (en) * 1979-06-21 1981-11-17 Ames-Yissum Ltd. Multilayer column chromatography specific binding assay method, test device and test kit
US4472371A (en) * 1979-10-29 1984-09-18 Summa Medical Corporation Radiolabeled antibody to anti-tumor associated antigen and process
US4362699A (en) 1981-03-10 1982-12-07 Bio Research, Inc. Apparatus for high pressure peptide synthesis
US4401646A (en) * 1981-05-08 1983-08-30 University Patents Inc. Method and apparatus for purifying materials radiolabeled with technetium-99m
US4775638A (en) * 1985-05-08 1988-10-04 Centocor, Inc. Single vial technique for radiolabeling protein
US4724213A (en) 1985-05-24 1988-02-09 Northwestern University Murine hybridoma Lym-1 and diagnostic antibody produced thereby
US4861581A (en) 1986-12-05 1989-08-29 Cancer Biologics, Inc. Detection of necrotic malignant tissue and associated therapy
US5019368A (en) 1989-02-23 1991-05-28 Cancer Biologics, Inc. Detection of necrotic malignant tissue and associated therapy
DE3705686C2 (de) * 1987-02-23 1995-11-30 Boehringer Mannheim Gmbh Verfahren zur Bestimmung von Antikörpern
US4874601A (en) * 1987-04-17 1989-10-17 Merck & Co., Inc. Radiolabelling kit
US4861579A (en) 1988-03-17 1989-08-29 American Cyanamid Company Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies
US6007817A (en) 1988-10-11 1999-12-28 University Of Southern California Vasopermeability enhancing immunoconjugates
US5194594A (en) 1990-09-07 1993-03-16 Techniclone, Inc. Modified antibodies
US5206346A (en) * 1990-12-05 1993-04-27 E. I. Du Pont De Nemours And Company Method for iodination/purification
US5450847A (en) * 1991-04-22 1995-09-19 Schering Aktiengesellschaft Process for making doses formulation of contrast media from concentrate
JP3135571B2 (ja) * 1991-05-01 2001-02-19 マリンクロッド・インコーポレイテッド 液状物質を搬送する方法および放射性核種発生器の自動溶出装置
US6036955A (en) 1992-03-05 2000-03-14 The Scripps Research Institute Kits and methods for the specific coagulation of vasculature
WO1993017715A1 (en) 1992-03-05 1993-09-16 Board Of Regents, The University Of Texas System Diagnostic and/or therapeutic agents, targeted to neovascular endothelial cells
US6093399A (en) 1992-03-05 2000-07-25 Board Of Regents, The University Of Texas System Methods and compositions for the specific coagulation of vasculature
US5776427A (en) 1992-03-05 1998-07-07 Board Of Regents, The University Of Texas System Methods for targeting the vasculature of solid tumors
US6749853B1 (en) 1992-03-05 2004-06-15 Board Of Regents, The University Of Texas System Combined methods and compositions for coagulation and tumor treatment
US5877289A (en) 1992-03-05 1999-03-02 The Scripps Research Institute Tissue factor compositions and ligands for the specific coagulation of vasculature
US5965132A (en) 1992-03-05 1999-10-12 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
US6004555A (en) 1992-03-05 1999-12-21 Board Of Regents, The University Of Texas System Methods for the specific coagulation of vasculature
US5605671A (en) * 1992-10-05 1997-02-25 The Regents Of The University Of Michigan Radiolabeled neutrophil activating peptides for imaging
US6241967B1 (en) * 1992-10-16 2001-06-05 Andreas Sachse Process and device for the production of liquid, disperse systems
EP0683396A1 (en) * 1993-02-04 1995-11-22 Sumitomo Pharmaceuticals Company, Limited Method of assaying specific antibody
AU6456496A (en) 1995-08-17 1997-03-12 Hybridon, Inc. Apparatus and process for multi-stage solid-phase synthesis of long-chained organic molecules
US7521531B2 (en) * 1996-08-28 2009-04-21 Immunomedics, Inc. Methods for the purification of stable radioiodine conjugates
AU750414B2 (en) 1998-07-13 2002-07-18 Board Of Regents, The University Of Texas System Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids
US6406693B1 (en) 1998-07-13 2002-06-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
US20020102208A1 (en) * 1999-03-01 2002-08-01 Paul Chinn Radiolabeling kit and binding assay
IL145941A (en) 1999-04-28 2007-08-19 Univ Texas Compositions and methods for cancer treatment by selectively inhibiting vegf
US6703020B1 (en) 1999-04-28 2004-03-09 Board Of Regents, The University Of Texas System Antibody conjugate methods for selectively inhibiting VEGF
DE10026903A1 (de) * 2000-06-03 2002-01-10 Cpc Cellular Process Chemistry Verfahren zur Herstellung von Chinolon-3-carbonsäuren
US6692702B1 (en) * 2000-07-07 2004-02-17 Coulter International Corp. Apparatus for biological sample preparation and analysis
CA2345838C (en) 2001-01-31 2010-02-02 Centre For Addiction And Mental Health Method for the synthesis of radiolabeled compounds
US6767319B2 (en) * 2001-06-29 2004-07-27 Medrad, Inc. Delivery methods, systems and components for use with hazardous pharmaceutical substances
WO2005003151A2 (en) * 2003-06-25 2005-01-13 Peregrine Pharmaceuticals, Inc. Method and apparatus for continuous large-scale radiolabeling of proteins

Also Published As

Publication number Publication date
AU2004253924B2 (en) 2009-07-30
EP1964847A2 (en) 2008-09-03
US8137540B2 (en) 2012-03-20
EP1638989B1 (en) 2008-07-30
CA2527054A1 (en) 2005-01-13
ATE402947T1 (de) 2008-08-15
HK1087417A1 (en) 2006-10-13
US20050123474A1 (en) 2005-06-09
EP1964847A3 (en) 2008-09-17
US7591953B2 (en) 2009-09-22
US20090312523A1 (en) 2009-12-17
CA2527054C (en) 2013-01-08
AU2004253924A1 (en) 2005-01-13
WO2005003151A2 (en) 2005-01-13
DE602004015454D1 (de) 2008-09-11
NZ543495A (en) 2009-04-30
EP1638989A2 (en) 2006-03-29
WO2005003151A3 (en) 2005-04-07

Similar Documents

Publication Publication Date Title
DK1501612T3 (da) Fremgangsmåde og apparat til udvælgelse af vægte
DK2308417T3 (da) Apparat og fremgangsmåder til tilvejebringelse af sorterede partikler
DK1946097T3 (da) Fremgangsmåde og apparat til pakning af kromatografisøjler
DK1195336T3 (da) Apparat og fremgangsmåde til inspektion af glasartikler
DK1954337T3 (da) Fremgangsmåde og apparat til injektion
NO20054033D0 (no) Fremgangsmate og apparat for pumpekvalitetskontroll ved formasjonsrateanalyseteknikker
DK1897396T3 (da) Fremgangsmåde og apparat til effektiv tilvejebringelse af planlægningsinformation
DK1606491T3 (da) Foringsrörfört bröndboringsperforerende apparat og fremgangsmåde
DK3862973T3 (da) Fremgangsmåde og apparat til repræsentation af billedgranularitet ved et eller flere parametre
DK1404512T3 (da) Fremgangsmåde og apparat til fremstilling af forstærket gipsplade
DE602004020306D1 (de) Photoleitfähiger bildherstellender Apparat, Bildherstellungsverfahren und Prozesskartusche
DK1479175T3 (da) Fremgangsmåde og apparat til synkronisering af basisstationer
NO20052181D0 (no) Fremgangsmate og apparat for a posisjonere et sentrum for en seismisk kilde
DK1641910T3 (da) Glucanaser, nucleinsyrer, som koder for disse, og fremgangsmåder til at fremstille og benytte disse
DK1342414T3 (da) Fremgangsmåde til måling af fugtighed i et apparat til behandling og tilberedelse af födevarer såvel som apparat til behandling og tilberedelse af födevarer
FI20010977A7 (fi) Kromatografinen erotusmenetelmä
NO20054603D0 (no) Apparat og metode for elektrostatisk prosessering av polymere formuleringer
NO20031569D0 (no) Fremgangsmåte og apparat for behandling av vann til en injeksjonsbrönn
DK1924514T3 (da) Apparat og fremgangsmåde til læsning af fødevarer
NO20032319D0 (no) Fremgangsmåte og apparat for videokomprimering
NO20044234L (no) Fremgangsmate og apparat for enturs-rorekspansjon
DK1701746T3 (da) Apparat til bio-dekontaminering af indelukker
DK1510174T3 (da) Apparat, fremgangsmåde og software til sporing af en genstand
DK3468045T3 (da) Fremgangsmåde og apparat til aritmetisk kodning
DK1481636T3 (da) Apparat, fremgangsmåde og software til sporing af et objekt