DK1641438T3 - Fremgangsmåde til fremstilling af den amorfe form af et lægemiddel - Google Patents
Fremgangsmåde til fremstilling af den amorfe form af et lægemiddelInfo
- Publication number
- DK1641438T3 DK1641438T3 DK05758626.5T DK05758626T DK1641438T3 DK 1641438 T3 DK1641438 T3 DK 1641438T3 DK 05758626 T DK05758626 T DK 05758626T DK 1641438 T3 DK1641438 T3 DK 1641438T3
- Authority
- DK
- Denmark
- Prior art keywords
- amorphous form
- drug
- preparing
- preparation
- active pharmaceutical
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B11/00—Machines or apparatus for drying solid materials or objects with movement which is non-progressive
- F26B11/12—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in stationary drums or other mainly-closed receptacles with moving stirring devices
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/041—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum for drying flowable materials, e.g. suspensions, bulk goods, in a continuous operation, e.g. with locks or other air tight arrangements for charging/discharging
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57621604P | 2004-06-01 | 2004-06-01 | |
| US58377804P | 2004-06-28 | 2004-06-28 | |
| US59970004P | 2004-08-05 | 2004-08-05 | |
| PCT/US2005/019485 WO2005117837A1 (en) | 2004-06-01 | 2005-06-01 | Process for preparation of amorphous form of a drug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1641438T3 true DK1641438T3 (da) | 2010-06-07 |
Family
ID=35134738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05758626.5T DK1641438T3 (da) | 2004-06-01 | 2005-06-01 | Fremgangsmåde til fremstilling af den amorfe form af et lægemiddel |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7589128B2 (da) |
| JP (1) | JP2008500405A (da) |
| KR (1) | KR20060123772A (da) |
| AT (1) | ATE458476T1 (da) |
| CA (1) | CA2560984A1 (da) |
| DE (1) | DE602005019509D1 (da) |
| DK (1) | DK1641438T3 (da) |
| ES (1) | ES2339682T3 (da) |
| IL (1) | IL179719A0 (da) |
| MX (1) | MXPA06010084A (da) |
| WO (1) | WO2005117837A1 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060083784A1 (en) * | 2002-08-07 | 2006-04-20 | Smithkline Beecham Corporation | Amorphous pharmaceutical compositions |
| KR20080112424A (ko) | 2004-10-15 | 2008-12-24 | 테바 파마슈티컬 인더스트리즈 리미티드 | 텔미사르탄의 제조 방법 |
| MX2007005348A (es) * | 2004-11-03 | 2007-06-25 | Teva Pharma | Formas amorfas y polimorficas de sodio de telmisartan. |
| CA2584358A1 (en) | 2004-12-01 | 2006-06-08 | Teva Gyogyszergyar Zartkoeruen Mukoedo Reszvenytarsasag | Non-hygroscopic and powdery amorphous pimecrolimus |
| WO2006079921A2 (en) | 2005-01-28 | 2006-08-03 | Pfizer Products Inc. | Drying of drug-containing particles |
| CN101213177A (zh) | 2005-07-05 | 2008-07-02 | 特瓦制药工业有限公司 | 孟鲁司特的纯化 |
| EP1948612A2 (en) * | 2005-11-16 | 2008-07-30 | Teva Pharmaceutical Industries Ltd | Drying methods of montelukast sodium by azeotropic removal of the solvent |
| GB0613925D0 (en) | 2006-07-13 | 2006-08-23 | Unilever Plc | Improvements relating to nanodispersions |
| PT2043610E (pt) | 2006-07-21 | 2015-10-22 | Bend Res Inc | Secagem de partículas contendo fármacos |
| GB2441328A (en) * | 2006-08-30 | 2008-03-05 | Alpharma Aps | A method for obtaining mupirocin calcium |
| US20080187684A1 (en) * | 2007-02-07 | 2008-08-07 | Imra America, Inc. | Method for depositing crystalline titania nanoparticles and films |
| US20090234125A1 (en) * | 2007-11-26 | 2009-09-17 | Eli Lancry | Amorphous retapamulin and processes for preparation thereof |
| GB2457452B (en) * | 2008-02-12 | 2010-05-12 | Pliva Lachema As | Amorphous form of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) amminedichloroplatinum (IV) |
| EP2366378A1 (en) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Sustained-release donepezil formulations |
| WO2011121596A2 (en) * | 2010-04-01 | 2011-10-06 | Neuland Laboratories Ltd. | Crystal modification of moxifloxacin hydrochloride |
| US8471030B2 (en) | 2010-12-06 | 2013-06-25 | Orochem Technologies Inc. | Purification of montelukast using simulated moving bed |
| US10966943B2 (en) | 2018-09-06 | 2021-04-06 | Innopharmascreen Inc. | Methods and compositions for treatment of asthma or parkinson's disease |
| WO2025146702A1 (en) * | 2024-01-03 | 2025-07-10 | Msn Laboratories Private Limited, R&D Center | Solid state forms of 1-{(2s,5r)-2-methyl-5-[(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino] piperidine-1-yl}prop-2-en-1-one 4-methylbenzene-1-sulfonic acid |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1643240A1 (de) * | 1966-09-16 | 1971-06-24 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung neuer racemischer oder optisch aktiver 1-Phenoxy-2-aminoalkane |
| GB1395907A (en) * | 1971-06-12 | 1975-05-29 | Beecham Group Ltd | Antibiotics |
| US3977943A (en) * | 1971-06-12 | 1976-08-31 | Beecham Group Limited | Antibiotics |
| US4071536A (en) * | 1971-06-12 | 1978-01-31 | Beecham Group Limited | Antibiotics |
| JPS5270083A (en) | 1975-12-04 | 1977-06-10 | Yoshitomi Pharmaceut Ind Ltd | Manufacture of an antibiotics, trans-pseudomonic acid |
| GB1577730A (en) * | 1976-10-23 | 1980-10-29 | Beecham Group Ltd | Treatment of infections with pseudomonicacid salts or esters thereof |
| GB1577545A (en) | 1977-07-27 | 1980-10-22 | Beecham Group Ltd | Treatment of swine dysenter |
| CA1103264A (en) * | 1977-09-30 | 1981-06-16 | Norman H. Rogers | Purification of pseudomonic acid |
| CA1115699A (en) * | 1978-05-20 | 1982-01-05 | Alan D. Curzons | Lithium pseudomonate and its preparation |
| CA1196284A (en) * | 1982-05-28 | 1985-11-05 | Joshua Oduro-Yeboah | Pharmaceutical formulations |
| GB8415579D0 (en) * | 1984-06-19 | 1984-07-25 | Beecham Group Plc | Compounds |
| GB8428952D0 (en) | 1984-11-16 | 1984-12-27 | Beecham Group Plc | Formulations |
| GB8530796D0 (en) * | 1985-12-13 | 1986-01-22 | Beecham Group Plc | Pharmaceutical composition |
| IE59628B1 (en) | 1986-06-26 | 1994-03-09 | Beecham Group Plc | Treatment of fungal infections |
| US5594026A (en) * | 1990-12-11 | 1997-01-14 | Smithkline Beecham Group P.L.C. | Polymorphs of crystalline mupirocin |
| US5292892A (en) * | 1991-05-07 | 1994-03-08 | Sankyo Company, Limited | Anti-bacterial compound and pharmaceutical compositions thereof |
| US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
| WO1998014189A1 (en) * | 1996-10-01 | 1998-04-09 | Smithkline Beecham Corporation | Use of mupirocin for the manufacture of a medicament for the treatment of bacterial infections associated with colonisation of the nasopharynx by pathogenic organisms |
| KR20010032550A (ko) * | 1997-11-26 | 2001-04-25 | 유니버설 프리저베이션 테크놀로지스 인코포레이티드 | 유리화에 의한 민감한 생물학적 시료의 보존방법 |
| US6231875B1 (en) * | 1998-03-31 | 2001-05-15 | Johnson & Johnson Consumer Companies, Inc. | Acidified composition for topical treatment of nail and skin conditions |
| US6306345B1 (en) * | 1998-05-06 | 2001-10-23 | Universal Preservation Technologies, Inc. | Industrial scale barrier technology for preservation of sensitive biological materials at ambient temperatures |
| HUP0105286A3 (en) * | 1999-02-03 | 2003-03-28 | Biogal Gyogyszergyar | Process for the isolation of pseudomonic acid a from pseudomonic acid complex-containing culture broth |
| HRP20010576A2 (en) | 1999-02-03 | 2002-08-31 | Biogal Gyogyszergyar | Process for the preparation of pseudomonic acid a antibiotic by microbiological method |
| IN191492B (da) | 1999-05-25 | 2003-12-06 | Ranbaxy Lab Ltd | |
| US6335023B1 (en) * | 1999-06-30 | 2002-01-01 | Ruey J. Yu | Oligosaccharide aldonic acids and their topical use |
| US6528086B2 (en) * | 1999-09-28 | 2003-03-04 | Zars, Inc. | Methods and apparatus for drug delivery involving phase changing formulations |
| IL137363A (en) * | 2000-07-18 | 2005-12-18 | Agis Ind 1983 Ltd | Pharmaceutical compositions containing mupirocin |
| EP1409703A4 (en) * | 2001-06-21 | 2004-08-18 | Biogal Gyogyszergyar | METABOLICALLY CONTROLLED FERMENTATION PROCESS FOR THE PRODUCTION OF PSEUDOMONIC ACID |
| DE60233496D1 (de) | 2001-07-11 | 2009-10-08 | Procter & Gamble | Verfahren zur oberflächenreinigung mittels eines dispergierten polymers |
| HRP20040642A2 (en) * | 2001-12-28 | 2005-10-31 | Teva Gy�gyszergy�r R�szv�nyt�rsas�g | Processes for preparing crystalline and amorphous mupirocin calcium |
| JP2005523260A (ja) | 2002-02-01 | 2005-08-04 | ファイザー・プロダクツ・インク | 圧力ノズルを用いた均質噴霧乾燥固体非晶質薬剤分散体の製造方法 |
| KR100664822B1 (ko) | 2002-02-01 | 2007-01-04 | 화이자 프로덕츠 인코포레이티드 | 변형된 분무-건조 장치를 이용한 균질한 분무-건조된 고체비결정성 약물 분산액의 제조 방법 |
| IL150907A (en) | 2002-07-25 | 2007-07-04 | Stephan Cherkez | Process for the preparation of stable amorphous calcium pseudomonate |
| CA2584358A1 (en) * | 2004-12-01 | 2006-06-08 | Teva Gyogyszergyar Zartkoeruen Mukoedo Reszvenytarsasag | Non-hygroscopic and powdery amorphous pimecrolimus |
-
2005
- 2005-06-01 US US11/143,312 patent/US7589128B2/en not_active Expired - Fee Related
- 2005-06-01 JP JP2007527596A patent/JP2008500405A/ja active Pending
- 2005-06-01 MX MXPA06010084A patent/MXPA06010084A/es unknown
- 2005-06-01 ES ES05758626T patent/ES2339682T3/es not_active Expired - Lifetime
- 2005-06-01 DK DK05758626.5T patent/DK1641438T3/da active
- 2005-06-01 AT AT05758626T patent/ATE458476T1/de not_active IP Right Cessation
- 2005-06-01 WO PCT/US2005/019485 patent/WO2005117837A1/en not_active Ceased
- 2005-06-01 KR KR1020067018664A patent/KR20060123772A/ko not_active Ceased
- 2005-06-01 DE DE602005019509T patent/DE602005019509D1/de not_active Expired - Lifetime
- 2005-06-01 CA CA002560984A patent/CA2560984A1/en not_active Abandoned
-
2006
- 2006-11-30 IL IL179719A patent/IL179719A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7589128B2 (en) | 2009-09-15 |
| ES2339682T3 (es) | 2010-05-24 |
| US20050272768A1 (en) | 2005-12-08 |
| KR20060123772A (ko) | 2006-12-04 |
| MXPA06010084A (es) | 2007-03-01 |
| CA2560984A1 (en) | 2005-12-15 |
| JP2008500405A (ja) | 2008-01-10 |
| WO2005117837A1 (en) | 2005-12-15 |
| IL179719A0 (en) | 2007-05-15 |
| DE602005019509D1 (de) | 2010-04-08 |
| ATE458476T1 (de) | 2010-03-15 |
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