DK16487A - Vacciner til oral indgift - Google Patents

Vacciner til oral indgift

Info

Publication number
DK16487A
DK16487A DK016487A DK16487A DK16487A DK 16487 A DK16487 A DK 16487A DK 016487 A DK016487 A DK 016487A DK 16487 A DK16487 A DK 16487A DK 16487 A DK16487 A DK 16487A
Authority
DK
Denmark
Prior art keywords
complex
immunogen
medicaments
well
cellular
Prior art date
Application number
DK016487A
Other languages
English (en)
Other versions
DK16487D0 (da
DK171846B1 (da
Inventor
Gregory John Russell-Jones
Henry James De Aizpurua
Peter Howe
Keith Norman Rand
Original Assignee
Biotech Australia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25642944&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK16487(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotech Australia Pty Ltd filed Critical Biotech Australia Pty Ltd
Publication of DK16487D0 publication Critical patent/DK16487D0/da
Publication of DK16487A publication Critical patent/DK16487A/da
Application granted granted Critical
Publication of DK171846B1 publication Critical patent/DK171846B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DK016487A 1985-05-15 1987-01-14 Et kompleks, en fremgangsmåde til fremstilling af dette kompleks, en transformant vært, et rekombinant DNA-molekyle og et medikament for den specifikke stimulering af serum og sekretoriske antistoffer via mucøs tilstedeværelse af antigener DK171846B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
AUPH056685 1985-05-15
AUPH056685 1985-05-15
AUPH310485 1985-10-25
AUPH310485 1985-10-25
AU8600135 1986-05-14
PCT/AU1986/000135 WO1986006635A1 (en) 1985-05-15 1986-05-14 Oral vaccines

Publications (3)

Publication Number Publication Date
DK16487D0 DK16487D0 (da) 1987-01-14
DK16487A true DK16487A (da) 1987-03-16
DK171846B1 DK171846B1 (da) 1997-06-30

Family

ID=25642944

Family Applications (1)

Application Number Title Priority Date Filing Date
DK016487A DK171846B1 (da) 1985-05-15 1987-01-14 Et kompleks, en fremgangsmåde til fremstilling af dette kompleks, en transformant vært, et rekombinant DNA-molekyle og et medikament for den specifikke stimulering af serum og sekretoriske antistoffer via mucøs tilstedeværelse af antigener

Country Status (12)

Country Link
EP (1) EP0222835B2 (da)
JP (1) JP2761849B2 (da)
CN (1) CN86103835A (da)
CA (1) CA1340555C (da)
DE (1) DE3650082T3 (da)
DK (1) DK171846B1 (da)
ES (1) ES8900006A1 (da)
FI (1) FI870140L (da)
HK (1) HK29896A (da)
IL (1) IL78775A (da)
NZ (1) NZ216162A (da)
WO (1) WO1986006635A1 (da)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8601940D0 (sv) * 1986-04-25 1986-04-25 Kabigen Ab Preparation of fused proteins, antibodies and processes therefor
US4822611A (en) * 1986-12-09 1989-04-18 Immunotec, Inc. Oral hyposensitization in the treatment of allergies
US5112749A (en) * 1987-10-02 1992-05-12 Praxis Biologics, Inc. Vaccines for the malaria circumsporozoite protein
US5135918A (en) * 1988-03-21 1992-08-04 Broncorp Method for decreasing reaginic antibody levels
IL91462A0 (en) * 1988-08-30 1990-04-29 Applied Research Systems Recombinant fusion proteins and dna encoding for such a protein
CA1339307C (en) * 1988-09-06 1997-08-19 Roy Curtiss, Iii Oral immunization by transgenic plants
US6043057A (en) * 1988-09-16 2000-03-28 Vitec Aktiebolag Recombinant systems for expression of the cholera B-sub-unit with the aid of foreign promoters and/or leader peptides
FR2636842B1 (fr) * 1988-09-27 1994-06-10 Liege Universite Etat Proteine de fusion d'une sequence derivee de la sous-unite b de la toxine cholerique et d'un antigene heterologue doue de proprietes immunogenes, compositions de vaccins les contenant et acides nucleiques recombinants contenant une sequence de nucleotides codant pour ladite proteine de fusion
AU4754490A (en) * 1988-12-07 1990-06-26 University Of Leicester Heat-labile toxin b subunit fusion proteins
WO1990007525A1 (en) * 1989-01-06 1990-07-12 The Regents Of The University Of California Keratoconjunctivitis cytotoxin and methods for its use and production
US6413523B1 (en) * 1989-06-02 2002-07-02 The United States Of America As Represented By The Secretary Of The Navy Pharmaceutical composition of escherichia coli heat-labile enterotoxin adjuvant and methods of use
DE69005572T2 (de) * 1989-09-08 1994-04-07 Takeda Chemical Industries Ltd Fusionsproteine und Herstellung davon.
US5032405A (en) * 1989-09-27 1991-07-16 Warner-Lambert Company Oral pharmaceutical composition for acid sensitive proteinaceous agents
US5378815A (en) * 1989-10-20 1995-01-03 National Research Council Canada Process for indirect targeted immunocytolysis
CA2050425A1 (en) * 1990-09-03 1992-03-04 Yoshiaki Uda Pharmaceutical composition and its mucous use
US5241053A (en) * 1990-09-05 1993-08-31 Takeda Chemical Industries, Ltd. Fused proteins comprising glycoprotein gD of HSV-1 and LTB
US5843463A (en) * 1990-12-21 1998-12-01 Antexbiologics, Inc. Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae
DE69130955T2 (de) * 1990-12-21 1999-07-01 Antex Biologics, Inc., Gaithersburg, Md. Adhesin-oligosaccharid-impfstoffkonjugate für -i(haemophilus influenza)
ES2149166T3 (es) * 1991-03-01 2000-11-01 Merial Sas Procedimiento de inmunoneutralizacion anti-lhrm de los animales domesticos machos no castrados y peptido para su realizacion.
DK0531497T3 (da) * 1991-04-02 1998-03-23 Biotech Australia Pty Ltd Orale indgivelsessystemer til mikropartikler
GB9112553D0 (en) * 1991-06-11 1991-07-31 Wellcome Found Fusion proteins
ZA934199B (en) * 1992-06-18 1994-01-10 Akzo Nv Carrier system against gnrh
DK0603992T4 (da) * 1992-12-22 2001-03-05 Univ Cincinnati Oral indgivelse af immunologisk aktive biomolekyler og andre terapeutiske proteiner
US5681571A (en) * 1993-10-08 1997-10-28 Duotol Ab Immunological tolerance-inducing agent
US5688506A (en) 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
US6485726B1 (en) 1995-01-17 2002-11-26 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
US6030613A (en) * 1995-01-17 2000-02-29 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
US6086875A (en) * 1995-01-17 2000-07-11 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of immunogens
EP1658772A3 (en) * 1995-01-17 2007-01-17 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of immunogens
CA2227871A1 (en) * 1995-07-26 1997-02-13 Maxim Pharmaceuticals, Inc. Mucosal delivery of polynucleotides
DE19534579C2 (de) * 1995-09-18 2000-06-08 Max Planck Gesellschaft Nucleinsäure-Moleküle codierend Proteine, die die Adhäsion von Neisseria-Zellen an humane Zellen vermitteln
JP2000510332A (ja) 1996-04-19 2000-08-15 ヘンリー エム．ジャクソン ファンデーション フォー ザ アドバンスメント オブ ミリタリー メディシン インチミンを単独で、または１以上の他の抗原との融合タンパク質として発現する宿主生物の投与による、免疫応答を刺激する方法
WO1997040161A1 (en) 1996-04-19 1997-10-30 Henry M. Jackson Foundation For The Advancement Of Military Medecine Histidine-tagged intimin and methods of using intimin to stimulate an immune response and as an antigen carrier with targeting capability
US6818222B1 (en) 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
KR20010043441A (ko) 1998-05-08 2001-05-25 더 유니버시티 오브 브리스톨 백신용 면역조절제
US7087236B1 (en) 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
ATE286511T1 (de) 1999-02-17 2005-01-15 Pfizer Prod Inc Fusionsproteine mit trägern welche eine doppelte immunantwort induzieren
FR2791895B1 (fr) * 1999-03-23 2001-06-15 Pasteur Merieux Serums Vacc Utilisation de trehalose pour stabiliser un vaccin liquide
EP1242122B1 (en) 1999-10-22 2009-09-30 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Delivery of proteins across polar epithelial cell layers
US6863896B1 (en) 1999-10-26 2005-03-08 Chiron Corporation Plant lectins as mucosal adjuvants
AU2471201A (en) * 1999-10-26 2001-06-06 Chiron Corporation Plant lectins as mucosal adjuvants
JP2001335510A (ja) * 2000-05-23 2001-12-04 Masanori Baba エイズワクチン
NZ561879A (en) * 2003-03-07 2009-05-31 Wyeth Corp Polysaccharide - staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections
ES2332524T3 (es) * 2004-07-20 2010-02-08 Symphogen A/S Un procedimiento para la caracterizacion de una linea celular policlonal.
US7713737B2 (en) 2004-10-04 2010-05-11 Trinity Biosystems, Inc. Methods and compositions for needleless delivery of macromolecules
EP1934246B8 (en) 2005-10-07 2012-02-08 Istituto di Ricerche di Biologia Molecolare P. Angeletti S.R.L. Matrix metalloproteinase 11 vaccine
US7666991B2 (en) 2005-12-05 2010-02-23 Trinity Biosystems, Inc. Compositions for needleless delivery of antibodies
ES2555544T3 (es) 2006-03-07 2016-01-04 Vaxinnate Corporation Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
SG190562A1 (en) 2008-04-18 2013-06-28 Vaxinnate Corp Deletion mutants of flagellin and methods of use
WO2011041003A2 (en) 2009-06-22 2011-04-07 Wyeth Llc Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
AU2010264538B2 (en) 2009-06-22 2013-10-03 Wyeth Llc Immunogenic compositions of Staphylococcus aureus antigens
CN101921726B (zh) * 2010-07-27 2012-08-22 浙江大学 一种口服免疫阻断鸡抑制素作用的转化子及其应用
CN102178699B (zh) * 2011-04-20 2013-03-20 威海康博尔生物药业有限公司 一种用于增强人体免疫力、促进生长发育的制剂
US8932598B2 (en) 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
JP6855469B2 (ja) 2015-10-16 2021-04-07 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 消化器標的療法のための処方物を調製するための工程

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2547224A1 (de) * 1974-11-01 1976-05-13 Sandoz Ag Organische verbindungen, ihre verwendung und herstellung
FR2306684A1 (fr) * 1975-04-11 1976-11-05 Crinex Lab Nouvelle composition a action immunostimulante
GB1553664A (en) * 1975-06-12 1979-09-26 Unilever Ltd Antigenic compositions
ZA802992B (en) * 1979-06-01 1981-10-28 Univ California Human pre-growth hormone
JPS5639022A (en) * 1979-09-05 1981-04-14 Hayashibara Biochem Lab Inc Preparation of vaccine
DE3110031A1 (de) * 1980-03-17 1982-01-07 President And Fellows Of Harvard College, Cambridge, Mass. Verschmolzene gene, ihre herstellung und verwendung derselben
EP0049945A3 (en) * 1980-09-15 1982-12-01 Bactex Incorporated Determining a hierarchy of piliated organisms and a vaccine prepared from such organisms
GB2094314A (en) * 1981-02-05 1982-09-15 Wellcome Found Recombinant DNA
WO1982003088A1 (en) * 1981-03-09 1982-09-16 Corp Cetus Vaccines
US4593002A (en) * 1982-01-11 1986-06-03 Salk Institute Biotechnology/Industrial Associates, Inc. Viruses with recombinant surface proteins
CA1203164A (en) * 1982-03-09 1986-04-15 Thomas J. Mckearn Antibody conjugates
ATE25197T1 (de) * 1982-05-12 1987-02-15 Harvard College Hybridproteinekodierende fusionierte gene, sie enthaltende klonierungsvektoren und deren verwendung.
US4496538A (en) * 1982-07-06 1985-01-29 Connaught Laboratories, Inc. Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine
DE3382547D1 (de) * 1983-01-12 1992-05-27 Chiron Corp Sekretorische expression in eukaryoten.
DK219084D0 (da) * 1984-05-02 1984-05-02 Frederik Carl Peter Lindberg Antigen
WO1985004654A1 (en) * 1984-04-06 1985-10-24 Scripps Clinic And Research Foundation A peptide vaccine or diagnostic, and a polypeptide useful therefor
US4808700A (en) * 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
EP0177343B1 (en) * 1984-10-05 1992-07-22 Genentech, Inc. Dna, cell cultures and methods for the secretion of heterologous proteins and periplasmic protein recovery
NZ213759A (en) * 1984-10-19 1989-01-27 Genentech Inc Lhrh-ctp protein conjugates influencing prolactin fsh and lh release
US4556555A (en) * 1985-01-25 1985-12-03 North Carolina State University Process for the immunological neutering of animals

Also Published As

Publication number Publication date
CN86103835A (zh) 1987-04-08
DE3650082D1 (de) 1994-11-03
AU594059B2 (en) 1990-03-01
FI870140A0 (fi) 1987-01-14
JP2761849B2 (ja) 1998-06-04
EP0222835B1 (en) 1994-09-28
FI870140A7 (fi) 1987-01-14
IL78775A (en) 1992-06-21
DK16487D0 (da) 1987-01-14
DK171846B1 (da) 1997-06-30
EP0222835B2 (en) 2000-04-19
IL78775A0 (en) 1986-08-31
FI870140L (fi) 1987-01-14
DE3650082T3 (de) 2000-12-21
DE3650082T2 (de) 1995-05-04
ES8900006A1 (es) 1988-10-16
NZ216162A (en) 1989-04-26
HK29896A (en) 1996-02-23
ES554969A0 (es) 1988-10-16
EP0222835A4 (en) 1988-02-01
CA1340555C (en) 1999-05-25
EP0222835A1 (en) 1987-05-27
JPH07213290A (ja) 1995-08-15
AU5861286A (en) 1986-12-04
WO1986006635A1 (en) 1986-11-20

Similar Documents

Publication Publication Date Title
NO175620C (no) Fremgangsmåte for fremstilling av et antitumorvirksomt legemiddel
SE7602317L (sv) 1,4-dihydropyridinkarbonsyraalkylestrar till anvendning som lekemedel och sett att framstella desamma
IT7905216A0 (it) Soluzione di amminoacidi per pazienti affetti da carcinoma.
DE3366494D1 (de) New 6-substituted-s-triazolo(3,4-a)phthalazine derivatives
DK0548114T5 (da) Mometason-furoat-monohydrat, fremgangsmåde til fremtilling deraf og farmaceutiske præparater indeholdende dette
NO833769L (no) Immunogent protein- eller peptidkompleks, fremgangsmaate for fremstilling og anvendelse herav som immunstimulerende middel og som vaksine
IS3284A7 (is) Aðferð við framleiðslu á N1-súbstitúeruðum bensimidasólafleiðum til að nota við lækningar
DE60038104D1 (de) Arzneimittelzubereitungen für die behandlung von alpha-galactosidase a-mangel
DK0526524T3 (da) Farmaceutiske præparater
IT8948599A0 (it) Procedimento per eliminare composti gassosi contaminanti, in particolare di droganti da gas vettori contenenti composti di alogenosilano
JPS5231839A (en) Drug for cosmetics and permanent wave in combination
IT1140521B (it) Sistema medicinale da somministrare per via intradermica per dinitrato di isosorbite
DE69422712D1 (de) Tris-platin-komplexe
BR9106272A (pt) Composicoes farmaceuticas contendo ipriflavona,processo para sua preparacao e uso terapeutico relativo
NL7903871A (nl) Werkwijze ter bereiding van een prostacycline bevattend farmaceutisch preparaat, alsmede als zodanig verkregen preparaten.
KR900007816A (ko) 사이클로프로필-치환된 아졸릴메틸카비놀, 이의 제조방법 및 약제로서의 이의 용도
DK52080A (da) Dehydropeptider fremgangsmaader til deres fremstilling samt deres anvendelse som laegemidler
DK102787D0 (da) Isohexidnucleosider og farmaceutiske praeparater indeholdende disse
NO920255L (no) Podofyllotoksinpreparat som inneholder triglyserider
IL89401A0 (en) Medicaments containing 1,4-dihydropyridine derivatives for the treatment of alcohol addiction
DK463283A (da) Glycosidbinding-relateret antigen, fremgangsmaade til fremstilling heraf og anticancermiddel indeholdende dette antigen som aktiv komponent
ES2037003T3 (es) Procedimiento para preparar peptidos empleando percloratos.
ATE137487T1 (de) Komplexe, enthaltend s(+)-phenyl-alkansäuren und alpha-hydroxy-alkansäuren
SE7509123L (sv) 3-metylpyrazol-5-karboxylat, sett att framstella desamma och lekemedelpreparat innehallande desamma.
DK645988A (da) Biphenylderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende samme

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
B1 Patent granted (law 1993)
PBP Patent lapsed