DK165326C - Monoklonale antistoffer mod humanrenin og derivater deraf samt fremgangsmaade til deres fremstilling, hybridoma-cellelinier samt fremgangsmaade til deres fremstilling, anvendelse af de monoklonale antistoffer og deres derivater samt testsaet indeholdende antistofferne og/eller deres derivater - Google Patents

Monoklonale antistoffer mod humanrenin og derivater deraf samt fremgangsmaade til deres fremstilling, hybridoma-cellelinier samt fremgangsmaade til deres fremstilling, anvendelse af de monoklonale antistoffer og deres derivater samt testsaet indeholdende antistofferne og/eller deres derivater

Info

Publication number
DK165326C
DK165326C DK153385A DK153385A DK165326C DK 165326 C DK165326 C DK 165326C DK 153385 A DK153385 A DK 153385A DK 153385 A DK153385 A DK 153385A DK 165326 C DK165326 C DK 165326C
Authority
DK
Denmark
Prior art keywords
antist
derivatives
preparation
monoclonal antibodies
cell lines
Prior art date
Application number
DK153385A
Other languages
English (en)
Other versions
DK153385D0 (da
DK153385A (da
DK165326B (da
Inventor
Christoph Heusser
Rudolf Heinrich Andreatta
Sefik Alkan
Jeanette Wood
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK153385D0 publication Critical patent/DK153385D0/da
Publication of DK153385A publication Critical patent/DK153385A/da
Publication of DK165326B publication Critical patent/DK165326B/da
Application granted granted Critical
Publication of DK165326C publication Critical patent/DK165326C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
DK153385A 1984-04-09 1985-04-03 Monoklonale antistoffer mod humanrenin og derivater deraf samt fremgangsmaade til deres fremstilling, hybridoma-cellelinier samt fremgangsmaade til deres fremstilling, anvendelse af de monoklonale antistoffer og deres derivater samt testsaet indeholdende antistofferne og/eller deres derivater DK165326C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH178184 1984-04-09
CH178184 1984-04-09

Publications (4)

Publication Number Publication Date
DK153385D0 DK153385D0 (da) 1985-04-03
DK153385A DK153385A (da) 1985-10-10
DK165326B DK165326B (da) 1992-11-09
DK165326C true DK165326C (da) 1993-03-29

Family

ID=4218460

Family Applications (1)

Application Number Title Priority Date Filing Date
DK153385A DK165326C (da) 1984-04-09 1985-04-03 Monoklonale antistoffer mod humanrenin og derivater deraf samt fremgangsmaade til deres fremstilling, hybridoma-cellelinier samt fremgangsmaade til deres fremstilling, anvendelse af de monoklonale antistoffer og deres derivater samt testsaet indeholdende antistofferne og/eller deres derivater

Country Status (13)

Country Link
US (1) US4780401A (da)
EP (1) EP0158599B1 (da)
JP (2) JPH0669390B2 (da)
AT (1) ATE57392T1 (da)
AU (1) AU591870B2 (da)
CA (1) CA1277261C (da)
DE (1) DE3580056D1 (da)
DK (1) DK165326C (da)
ES (2) ES8707295A1 (da)
FI (1) FI87933C (da)
IE (1) IE57956B1 (da)
NO (1) NO165556C (da)
ZA (1) ZA852557B (da)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972990A (en) * 1992-04-10 1999-10-26 Brigham And Women's Hospital, Inc. Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
AU4250893A (en) * 1992-05-14 1993-12-13 L.R.S. Diagnostics, Inc. Methods and novel proteins associated with low renin syndrome
DE69322847T2 (de) * 1993-01-13 1999-05-27 Idemitsu Kosan Co. Ltd., Tokio/Tokyo Monoklonaler Antikörper gegen menschliches Ceruloplasmin
WO1994020857A1 (en) * 1993-03-11 1994-09-15 The Regents Of The University Of California Assay for humoral immunity to macromolecules
US6911528B1 (en) * 1994-12-02 2005-06-28 The Johns Hopkins University School Of Medicine Hedgehog-derived polypeptides
US20030167483A1 (en) * 1998-06-24 2003-09-04 Farese Robert V. Diacylglycerol O-acyltransferase
ATE532070T1 (de) 2000-12-14 2011-11-15 Brigham & Womens Hospital Entzündungsmarker zum nachweis und zur prävention von diabetes mellitus
PT3072978T (pt) 2002-05-09 2018-10-15 Brigham & Womens Hospital Inc 1l1rl-1 como um marcador de doença cardiovascular
US7273616B2 (en) * 2002-05-10 2007-09-25 The Trustees Of Columbia University In The City Of New York Genetically engineered cell lines and systems for propagating Varicella zoster virus and methods of use thereof
EP1670459A4 (en) * 2003-08-20 2009-03-25 Nitromed Inc NITROSED AND NITROSYLATED CARDIOVASCULAR COMPOUNDS, COMPOSITIONS AND APPLICATION METHODS
JP2007504136A (ja) * 2003-08-28 2007-03-01 ニトロメッド インコーポレーティッド ニトロソ化およびニトロシル化利尿化合物、組成物、ならびに使用方法
DK2384753T3 (da) 2003-08-29 2016-04-11 Brigham & Womens Hospital Hydantoinderivater som inhibitorer for cellenekrose
ATE546734T1 (de) 2003-12-05 2012-03-15 Cleveland Clinic Foundation Risikomarker für eine herzkreislaufkrankheit
US20090131342A1 (en) * 2004-01-22 2009-05-21 Nitromed, Inc. Nitrosated and/or nitrosylated compounds, compositions and methods of use
US7803838B2 (en) * 2004-06-04 2010-09-28 Forest Laboratories Holdings Limited Compositions comprising nebivolol
WO2006041855A2 (en) 2004-10-04 2006-04-20 Nitromed, Inc. Compositions and methods using apocynin compounds and nitric oxide donors
CA2624601C (en) 2004-10-06 2018-07-03 The Brigham And Women's Hospital, Inc. Relevance of achieved levels of markers of systemic inflammation following treatment
US20080275093A1 (en) * 2004-11-15 2008-11-06 Nitromed, Inc. Diuretic Compounds Comprising Heterocyclic Nitric Oxide Donor Groups, Compositions and Methods of Use
CA2595579A1 (en) * 2005-01-21 2006-07-27 Nitromed, Inc. Cardiovascular compounds comprising heterocyclic nitric oxide donor group compositions and methods of use
JP2008528626A (ja) * 2005-01-31 2008-07-31 マイラン ラボラトリーズ インク． ヒドロキシル化されたネビボロールを含む薬学的組成物
EP1858525A2 (en) * 2005-02-16 2007-11-28 Nitromed, Inc. Organic nitric oxide donor salts of antimicrobial compounds, compositions and methods of use
WO2006093864A1 (en) * 2005-02-28 2006-09-08 Nitromed, Inc. Cardiovascular compounds comprising nitric oxide enhancing groups, compositions and methods of use
WO2006099058A2 (en) * 2005-03-09 2006-09-21 Nitromed, Inc. Organic nitric oxide enhancing salts of angiotensin ii antagonists, compositions and methods of use
KR101310037B1 (ko) 2005-05-31 2013-09-24 밀란 인크. 네비볼롤을 함유하는 조성물
WO2007016677A2 (en) 2005-08-02 2007-02-08 Nitromed, Inc. Nitric oxide enhancing antimicrobial compounds, compositions and methods of use
US20090054381A1 (en) * 2005-10-04 2009-02-26 Nitromed, Inc. Methods for treating respiratory disorders
US8119358B2 (en) 2005-10-11 2012-02-21 Tethys Bioscience, Inc. Diabetes-related biomarkers and methods of use thereof
WO2007059311A2 (en) * 2005-11-16 2007-05-24 Nitromed, Inc. Furoxan compounds, compositions and methods of use
EP1968584A2 (en) * 2005-12-20 2008-09-17 Nitromed, Inc. Nitric oxide enhancing glutamic acid compounds, compositions and methods of use
WO2007075542A2 (en) * 2005-12-22 2007-07-05 Nitromed, Inc. Nitric oxide enhancing pyruvate compounds, compositions and methods of use
CA2659082A1 (en) 2006-06-07 2007-12-21 Tethys Bioscience, Inc. Markers associated with arteriovascular events and methods of use thereof
US7897360B2 (en) * 2006-12-15 2011-03-01 Kimberly-Clark Worldwide, Inc. Enzyme detection techniques
BRPI0810409A2 (pt) 2007-04-18 2015-02-18 Thethys Bioscience Inc Biomarcadores relacionados ao diabetes e métodos de uso destes
US7828840B2 (en) * 2007-11-15 2010-11-09 Med Institute, Inc. Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
GB2460915B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor
TW201201764A (en) 2010-02-01 2012-01-16 Hospital For Sick Children Remote ischemic conditioning for treatment and prevention of restenosis
SG10201908570RA (en) 2010-03-31 2019-11-28 Hospital For Sick Children Use of remote ischemic conditioning to improve outcome after myocardial infarction
CN104640856B (zh) 2012-05-11 2017-09-15 复位治疗公司 作为隐花色素调节剂的含有咔唑的磺酰胺类
WO2014022195A1 (en) 2012-08-01 2014-02-06 Tavakoli Zahra Free flowing, frozen compositions comprising a therapeutic agent
EP2968276A4 (en) 2013-03-15 2017-02-15 President and Fellows of Harvard College Hybrid necroptosis inhibitors
TWI690521B (zh) 2014-04-07 2020-04-11 美商同步製藥公司 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
EP3537152B1 (en) * 2016-10-21 2023-06-14 Fujirebio Inc. Immunoassay method for determining renin concentration
CN107007849A (zh) * 2017-06-19 2017-08-04 河北省人民医院 一种建立甲减性心功能不全大鼠动物模型的方法
CN118725125B (zh) * 2023-03-30 2025-08-08 东莞市朋志生物科技有限公司 抗肾素抗体、检测肾素的试剂和试剂盒
CN118772283B (zh) * 2023-04-07 2025-09-16 东莞市朋志生物科技有限公司 抗肾素抗体、检测肾素的试剂和试剂盒

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies

Also Published As

Publication number Publication date
US4780401A (en) 1988-10-25
AU4088685A (en) 1985-10-17
DK153385D0 (da) 1985-04-03
IE850876L (en) 1985-10-09
AU591870B2 (en) 1989-12-21
FI87933C (fi) 1993-03-10
CA1277261C (en) 1990-12-04
ES557016A0 (es) 1988-04-16
EP0158599B1 (de) 1990-10-10
FI851334A0 (fi) 1985-04-03
DK153385A (da) 1985-10-10
ES8707295A1 (es) 1987-07-16
NO165556B (no) 1990-11-19
DK165326B (da) 1992-11-09
EP0158599A3 (en) 1987-12-16
NO165556C (no) 1991-02-27
JPS60231624A (ja) 1985-11-18
FI87933B (fi) 1992-11-30
EP0158599A2 (de) 1985-10-16
IE57956B1 (en) 1993-05-19
JPH0669371B2 (ja) 1994-09-07
FI851334L (fi) 1985-10-10
ES542017A0 (es) 1987-07-16
ATE57392T1 (de) 1990-10-15
ES8802254A1 (es) 1988-04-16
JPS6485070A (en) 1989-03-30
JPH0669390B2 (ja) 1994-09-07
NO851384L (no) 1985-10-10
ZA852557B (en) 1985-11-27
DE3580056D1 (de) 1990-11-15

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