DK165788C - Optisk isomer af et imidazolderivat samt fremstilling og anvendelse af denne - Google Patents

Optisk isomer af et imidazolderivat samt fremstilling og anvendelse af denne

Info

Publication number: DK165788C
Authority: DK; Denmark
Prior art keywords: isoms; imidazold; derivative; optical; preparation
Prior art date: 1987-07-16

Application number

DK386288A

Other languages

Danish (da)

English (en)

Other versions

DK386288D0 (da

DK386288A (da

DK165788B (da

Inventor

Arto Johannes Karjalainen

Raimo Einari Virtanen

Eino Juhani Savolainen

Original Assignee

Orion Yhtymae Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-16

Filing date

1988-07-11

Publication date

1993-06-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10620775&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK165788(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1988-07-11 Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy

1988-07-11 Publication of DK386288D0 publication Critical patent/DK386288D0/da

1989-01-17 Publication of DK386288A publication Critical patent/DK386288A/da

1993-01-18 Publication of DK165788B publication Critical patent/DK165788B/da

1993-06-14 Application granted granted Critical

1993-06-14 Publication of DK165788C publication Critical patent/DK165788C/da

Links

230000003287 optical effect Effects 0.000 title 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
HRLIOXLXPOHXTA-UHFFFAOYSA-N medetomidine Chemical compound C=1C=CC(C)=C(C)C=1C(C)C1=CN=C[N]1 HRLIOXLXPOHXTA-UHFFFAOYSA-N 0.000 abstract 1
229960002140 medetomidine Drugs 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
239000000018 receptor agonist Substances 0.000 abstract 1
229940044601 receptor agonist Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Optical Record Carriers And Manufacture Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Photoreceptors In Electrophotography (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK386288A 1987-07-16 1988-07-11 Optisk isomer af et imidazolderivat samt fremstilling og anvendelse af denne DK165788C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8716803A GB2206880B (en)	1987-07-16	1987-07-16	Optical isomers of an imidazole derivative
GB8716803		1987-07-16

Publications (4)

Publication Number	Publication Date
DK386288D0 DK386288D0 (da)	1988-07-11
DK386288A DK386288A (da)	1989-01-17
DK165788B DK165788B (da)	1993-01-18
DK165788C true DK165788C (da)	1993-06-14

Family

ID=10620775

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK386288A DK165788C (da)	1987-07-16	1988-07-11	Optisk isomer af et imidazolderivat samt fremstilling og anvendelse af denne

Country Status (29)

Country	Link
US (1)	US4910214A (fr)
EP (1)	EP0300652B1 (fr)
JP (1)	JPH0625138B2 (fr)
KR (1)	KR940007311B1 (fr)
CN (1)	CN1022323C (fr)
AT (1)	ATE71941T1 (fr)
AU (1)	AU600839B2 (fr)
BG (1)	BG60473B2 (fr)
CA (1)	CA1337659C (fr)
CY (2)	CY1787A (fr)
DD (1)	DD281807A5 (fr)
DE (2)	DE3867945D1 (fr)
DK (1)	DK165788C (fr)
ES (1)	ES2038757T3 (fr)
FI (1)	FI95375C (fr)
GB (1)	GB2206880B (fr)
GR (1)	GR3003878T3 (fr)
HK (1)	HK56094A (fr)
HU (1)	HU198693B (fr)
IE (1)	IE60456B1 (fr)
IL (1)	IL87076A0 (fr)
LU (1)	LU91010I2 (fr)
NL (1)	NL300117I2 (fr)
NO (2)	NO170579C (fr)
NZ (1)	NZ225362A (fr)
PT (1)	PT88013B (fr)
SU (1)	SU1648248A3 (fr)
UA (1)	UA5560A1 (fr)
ZA (1)	ZA885134B (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2215206B (en) *	1988-02-29	1991-07-03	Farmos Oy	4-substituted imidazole derivatives useful in perioperative care
US5124157A (en) *	1989-08-18	1992-06-23	Cygnus Therapeutic Systems	Method and device for administering dexmedetomidine transdermally
US5120713A (en) *	1990-09-10	1992-06-09	Applied Research Systems Ars Holding N.V.	Treatment of obesity with an alpha-2-adrenergic agonist and a growth hormone releasing peptide
GB9111732D0 (en) *	1991-05-31	1991-07-24	Orion Yhtymae Oy	The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs
GB2281206A (en) *	1993-08-25	1995-03-01	Orion Yhtymae Oy	Use of dexmedetomidine
GB9425211D0 (en) *	1994-12-14	1995-02-15	Ucb Sa	Substituted 1H-imidazoles
IN187238B (fr) *	1995-06-30	2002-03-09	Astra Ab
GB9521680D0 (en) *	1995-10-23	1996-01-03	Orion Yhtymo Oy	New use of imidazole derivatives
US5866579A (en)	1997-04-11	1999-02-02	Synaptic Pharmaceutical Corporation	Imidazole and imidazoline derivatives and uses thereof
US6716867B1 (en)	1998-04-01	2004-04-06	Orion Corporation	Use of dexmedetomidine for ICU sedation
AR015744A1 (es) *	1998-04-01	2001-05-16	Orion Corp	Uso de dexmedetomidina para sedacion en terapia intensiva
DE60024855T2 (de)	1999-10-29	2006-08-31	Orion Corp.	Verwendung eines imidazolderivats zur behandlung oder verhütung von hypotension und schock
US6388090B2 (en) *	2000-01-14	2002-05-14	Orion Corporation	Imidazole derivatives
US7141597B2 (en) *	2003-09-12	2006-11-28	Allergan, Inc.	Nonsedating α-2 agonists
WO2007056457A2 (fr)	2005-11-09	2007-05-18	Combinatorx, Incorporated	Procedes, compositions et kits pour le traitement de pathologies
CN102488652B (zh)	2006-03-16	2014-06-18	特瑞斯制药股份有限公司	含有药物-离子交换树脂复合物的经修饰释放的制剂
US7795263B2 (en) *	2008-07-08	2010-09-14	Wildlife Laboratories, Inc.	Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
US20100196286A1 (en) *	2008-12-01	2010-08-05	Armer Thomas A	Inhalation delivery methods and devices
WO2010074753A1 (fr)	2008-12-23	2010-07-01	Map Pharmaceuticals, Inc.	Dispositifs d'inhalation et procédés associés pour administration de composés hypnotiques sédatifs
RU2572692C2 (ru) *	2009-05-15	2016-01-20	Рекро Фарма, Инк.	Сублингвальные композиции дексмедетомидина и способы их применения
CN101671305A (zh) *	2009-09-29	2010-03-17	北京华禧联合科技发展有限公司	一种拆分美托咪定的左旋及右旋对映体的方法
CN102464619A (zh) *	2010-11-17	2012-05-23	桑迪亚医药技术（上海）有限责任公司	一种左旋4-[1-(2,3-二甲基苯基)乙基]-1r-咪唑消旋化方法
US20130096170A1 (en)	2011-10-14	2013-04-18	Hospira, Inc.	Methods of treating pediatric patients using dexmedetomidine
WO2013069025A1 (fr)	2011-11-11	2013-05-16	Neon Laboratories Ltd.	Procédé de préparation de la dexmédétomidine
AU2012352528B9 (en)	2011-12-11	2017-11-02	Baudax Bio, Inc.	Intranasal dexmedetomidine compositions and methods of use thereof
US8242158B1 (en)	2012-01-04	2012-08-14	Hospira, Inc.	Dexmedetomidine premix formulation
ITMI20120311A1 (it) *	2012-02-29	2013-08-30	Edmond Pharma Srl	Procedimento per la risoluzione di medetomidina e recupero dell'enantiomero indesiderato
CA2880456A1 (fr)	2012-08-15	2014-02-20	Tris Pharma, Inc.	Comprime a croquer de methylphenidate a liberation modifiee
DK2906213T3 (en) *	2012-10-15	2018-02-19	Orion Corp	VETERINARY PROCEDURE FOR RELIEFING NOISE SENSITIVITY
CA2924233C (fr)	2013-10-07	2018-10-23	Teikoku Pharma Usa, Inc.	Methodes et compositions permettant de traiter le trouble d'hyperactivite avec deficit de l'attention, l'anxiete et l'insomnie a l'aide de compositions transdermiques de dexmedetomidine
BR112016006848A2 (pt)	2013-10-07	2017-08-01	Teikoku Pharma Usa Inc	métodos e composições para distribuição transdérmica de uma quantidade não sedativa de dexmedetomidina
KR101827980B1 (ko)	2013-10-07	2018-02-13	테이코쿠 팔마 유에스에이, 인코포레이티드	덱스메데토미딘 경피 전달 장치 및 이의 사용 방법
CN105175339B (zh) *	2015-10-09	2018-01-16	辰欣药业股份有限公司	一种制备盐酸右美托咪定的方法
US9717796B1 (en)	2016-04-20	2017-08-01	Slypharma, Llc	Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container
FR3054218B1 (fr) *	2016-07-22	2020-03-06	Universite De Rouen	Procede de dedoublement de sels de baclofene
TWI764951B (zh)	2016-10-31	2022-05-21	美商帝國製藥美國股份有限公司	用於處理疼痛之右美托咪啶經皮遞送裝置
US11160791B2 (en)	2018-11-01	2021-11-02	Medefil, Inc.	Dexmedetomidine injection premix formulation in ready to use (RTU) bags
CN115197149B (zh) *	2021-04-02	2023-09-22	四川大学华西医院	一种5-苄基咪唑类化合物及其制备方法和用途
CN114671811A (zh) *	2022-04-14	2022-06-28	南京正科医药股份有限公司	一种右美托咪定拆分副产物的外消旋化回收方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU518569B2 (en) *	1979-08-07	1981-10-08	Farmos-Yhtyma Oy	4-benzyl- and 4-benzoyl imidazole derivatives
GB2092569B (en) *	1981-02-05	1984-09-19	Farmos Oy	Substituted imidazole derivatives and their preparation and use
GB2101114B (en) *	1981-07-10	1985-05-22	Farmos Group Ltd	Substituted imidazole derivatives and their preparation and use
FI844786A0 (fi)	1984-12-04	1984-12-04	Farmos Oy	Terapeutiskt utnyttjbar foerening.
DE3531682A1 (de) *	1985-09-05	1987-03-12	Thomae Gmbh Dr K	(+)-6-chlor-5,10-dihydro-5-((1-methyl-4- piperidinyl)acetyl)-11h-dibenzo(b,e)(1,4) diazepin-11-on, seine isolierung und verwendung als arzneimittel

1987
- 1987-07-16 GB GB8716803A patent/GB2206880B/en not_active Expired - Lifetime
1988
- 1988-06-14 FI FI882819A patent/FI95375C/fi active Protection Beyond IP Right Term
- 1988-06-28 SU SU884356076A patent/SU1648248A3/ru active
- 1988-06-28 UA UA4356076A patent/UA5560A1/uk unknown
- 1988-07-08 AT AT88306250T patent/ATE71941T1/de active
- 1988-07-08 ES ES198888306250T patent/ES2038757T3/es not_active Expired - Lifetime
- 1988-07-08 DE DE8888306250T patent/DE3867945D1/de not_active Expired - Lifetime
- 1988-07-08 DE DE2003199005 patent/DE10399005I2/de active Active
- 1988-07-08 EP EP88306250A patent/EP0300652B1/fr not_active Expired - Lifetime
- 1988-07-11 DK DK386288A patent/DK165788C/da not_active IP Right Cessation
- 1988-07-11 AU AU18941/88A patent/AU600839B2/en not_active Expired
- 1988-07-11 NZ NZ225362A patent/NZ225362A/xx unknown
- 1988-07-12 IL IL87076A patent/IL87076A0/xx not_active IP Right Cessation
- 1988-07-14 DD DD88317936A patent/DD281807A5/de not_active IP Right Cessation
- 1988-07-14 CA CA000572086A patent/CA1337659C/fr not_active Expired - Lifetime
- 1988-07-15 IE IE217488A patent/IE60456B1/en not_active IP Right Cessation
- 1988-07-15 HU HU883708A patent/HU198693B/hu unknown
- 1988-07-15 PT PT88013A patent/PT88013B/pt not_active IP Right Cessation
- 1988-07-15 ZA ZA885134A patent/ZA885134B/xx unknown
- 1988-07-15 KR KR1019880008937A patent/KR940007311B1/ko not_active Expired - Lifetime
- 1988-07-15 US US07/219,637 patent/US4910214A/en not_active Expired - Lifetime
- 1988-07-15 NO NO883155A patent/NO170579C/no not_active IP Right Cessation
- 1988-07-16 CN CN88104440A patent/CN1022323C/zh not_active Expired - Lifetime
- 1988-07-16 JP JP63177959A patent/JPH0625138B2/ja not_active Expired - Lifetime
1992
- 1992-02-21 GR GR920400299T patent/GR3003878T3/el unknown
1994
- 1994-01-18 BG BG098380A patent/BG60473B2/bg unknown
- 1994-05-24 HK HK56094A patent/HK56094A/en not_active IP Right Cessation
1995
- 1995-10-20 CY CY178795A patent/CY1787A/xx unknown
2003
- 2003-02-14 LU LU91010C patent/LU91010I2/fr unknown
- 2003-03-03 NL NL300117C patent/NL300117I2/nl unknown
- 2003-07-01 NO NO2003004C patent/NO2003004I2/no unknown
2004
- 2004-10-27 CY CY200400006C patent/CY2004006I1/el unknown

Also Published As

Publication number	Publication date
NO883155D0 (no)	1988-07-15
DE10399005I2 (de)	2012-06-06
GR3003878T3 (fr)	1993-03-16
IE60456B1 (en)	1994-07-13
KR940007311B1 (ko)	1994-08-12
NO883155L (no)	1989-01-17
PT88013A (pt)	1989-06-30
IE882174L (en)	1989-01-16
GB2206880A (en)	1989-01-18
LU91010I2 (fr)	2003-06-19
KR890002030A (ko)	1989-04-07
BG60473B2 (bg)	1995-04-28
UA5560A1 (uk)	1994-12-28
CN1022323C (zh)	1993-10-06
PT88013B (pt)	1995-03-01
CA1337659C (fr)	1995-11-28
US4910214A (en)	1990-03-20
SU1648248A3 (ru)	1991-05-07
ATE71941T1 (de)	1992-02-15
DK386288D0 (da)	1988-07-11
HK56094A (en)	1994-06-03
DE3867945D1 (de)	1992-03-05
HU198693B (en)	1989-11-28
ES2038757T3 (es)	1993-08-01
GB8716803D0 (en)	1987-08-19
NL300117I1 (nl)	2003-05-01
JPH0625138B2 (ja)	1994-04-06
IL87076A0 (en)	1988-12-30
CN1030576A (zh)	1989-01-25
NO170579B (no)	1992-07-27
EP0300652B1 (fr)	1992-01-22
NO2003004I2 (no)	2005-03-21
FI95375B (fi)	1995-10-13
CY2004006I2 (el)	2009-11-04
GB2206880B (en)	1991-04-24
FI882819L (fi)	1989-01-17
FI882819A0 (fi)	1988-06-14
HUT48218A (en)	1989-05-29
DD281807A5 (de)	1990-08-22
CY1787A (en)	1995-10-20
DK386288A (da)	1989-01-17
AU1894188A (en)	1989-01-19
AU600839B2 (en)	1990-08-23
NO170579C (no)	1992-11-04
FI95375C (fi)	1996-01-25
NZ225362A (en)	1990-07-26
DK165788B (da)	1993-01-18
NL300117I2 (nl)	2003-10-01
ZA885134B (en)	1989-04-26
JPS6434968A (en)	1989-02-06
CY2004006I1 (el)	2009-11-04
EP0300652A1 (fr)	1989-01-25
DE10399005I1 (de)	2003-06-05

Legal Events

Date

Code

Title

Description

2006-09-25

CTFG

Supplementary protection certificate (spc) issued

Free format text: PRODUCT NAME: DEXMEDETOMIDIN HYDROCHLORID

Spc suppl protection certif: CA 2003 00003

Filing date: 20030218

2008-07-28

PUP

Patent expired

Publication	Publication Date	Title
DK165788C (da)	1993-06-14	Optisk isomer af et imidazolderivat samt fremstilling og anvendelse af denne
IT1211431B (it)	1989-10-26	Disco per registrazione ottica
DK318688A (da)	1989-02-14	Reagensglasholder
DE3679519D1 (de)	1991-07-04	Optische kopfeinrichtungen.
DE3854235D1 (de)	1995-08-31	Automatische einstellung der werkzeugspitze.
DK584288A (da)	1989-04-23	Fremgangsmaade til fremstilling af guaninderivater
DK63388A (da)	1988-02-08	Isocyanomethylforbindelse samt fremgangsmaade til fremstilling af et oxadiazolimidazobenzodiazepinderivat
DE3873562D1 (de)	1992-09-17	Beta-alkylmelatonine.
GR880100869A (el)	1994-03-31	Μέ?οδος παρασκευής παραγώγων υποκατεστημένου στυρολίου.
DK610788A (da)	1989-07-01	Linseholder
DK157685A (da)	1985-10-11	Optisk afsoegningsapparat
DK119588D0 (da)	1988-03-04	27-halogen-derivater af ll-f28249-forbindelser
DK219183A (da)	1983-11-19	Enantiomere af 2,3,3a,4,5,6-hexahydro-1h-indolo(3,2,1-de)(1,5-naphthyridin), fremgangsmaade til deres adskillelse samt deres anvendelse
IT1213810B (it)	1990-01-05	Congegno ottico-meccanico per la determinazione dell'asse ottico
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