DK165939C - Metropololpraeparat med styret, kontinuerlig afgivelse af det aktive stof, farmaceutisk praeparat indeholdende samme og fremgangsmaade til fremstilling af metropololpraeparatet samt anvendelse af metropololpraeparatet til fremstilling af et farmaceutisk praeparat til behandling af kardiovaskulaere lidelser - Google Patents
Metropololpraeparat med styret, kontinuerlig afgivelse af det aktive stof, farmaceutisk praeparat indeholdende samme og fremgangsmaade til fremstilling af metropololpraeparatet samt anvendelse af metropololpraeparatet til fremstilling af et farmaceutisk praeparat til behandling af kardiovaskulaere lidelserInfo
- Publication number
- DK165939C DK165939C DK478186A DK478186A DK165939C DK 165939 C DK165939 C DK 165939C DK 478186 A DK478186 A DK 478186A DK 478186 A DK478186 A DK 478186A DK 165939 C DK165939 C DK 165939C
- Authority
- DK
- Denmark
- Prior art keywords
- metropololpraeparatet
- treatment
- metropololpraeparat
- creating
- preparation containing
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000011324 bead Substances 0.000 abstract 1
- 239000003405 delayed action preparation Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- IUBSYMUCCVWXPE-UHFFFAOYSA-N metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 abstract 1
- 229960002237 metoprolol Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8504721A SE455836B (sv) | 1985-10-11 | 1985-10-11 | Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning |
| SE8504721 | 1985-10-11 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK478186D0 DK478186D0 (da) | 1986-10-07 |
| DK478186A DK478186A (da) | 1987-04-12 |
| DK165939B DK165939B (da) | 1993-02-15 |
| DK165939C true DK165939C (da) | 1993-07-05 |
Family
ID=20361706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK478186A DK165939C (da) | 1985-10-11 | 1986-10-07 | Metropololpraeparat med styret, kontinuerlig afgivelse af det aktive stof, farmaceutisk praeparat indeholdende samme og fremgangsmaade til fremstilling af metropololpraeparatet samt anvendelse af metropololpraeparatet til fremstilling af et farmaceutisk praeparat til behandling af kardiovaskulaere lidelser |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US4957745A (is) |
| EP (1) | EP0220143B1 (is) |
| JP (1) | JPH0759506B2 (is) |
| KR (1) | KR940000100B1 (is) |
| CN (1) | CN1023293C (is) |
| AT (1) | ATE65391T1 (is) |
| AU (1) | AU588630B2 (is) |
| CY (1) | CY1616A (is) |
| DD (1) | DD259789A5 (is) |
| DE (2) | DE3680450D1 (is) |
| DK (1) | DK165939C (is) |
| DZ (1) | DZ994A1 (is) |
| ES (1) | ES2003863B3 (is) |
| FI (1) | FI88579C (is) |
| GB (1) | GB2181348B (is) |
| GR (2) | GR890300059T1 (is) |
| HK (1) | HK101791A (is) |
| HU (1) | HU197839B (is) |
| IE (1) | IE59053B1 (is) |
| IS (1) | IS1529B (is) |
| LT (2) | LTIP1680A (is) |
| LV (3) | LV10913B (is) |
| NO (1) | NO172276C (is) |
| NZ (1) | NZ217696A (is) |
| PH (1) | PH22277A (is) |
| PL (1) | PL261802A1 (is) |
| PT (1) | PT83509B (is) |
| RU (1) | RU2072840C1 (is) |
| SE (1) | SE455836B (is) |
| SG (1) | SG95291G (is) |
| SU (1) | SU1760969A3 (is) |
| UA (2) | UA26211A (is) |
| ZA (1) | ZA869860B (is) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8703881D0 (sv) * | 1987-10-08 | 1987-10-08 | Haessle Ab | New pharmaceutical preparation |
| US4892739A (en) * | 1988-04-25 | 1990-01-09 | Ciba-Geigy Corporation | Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties |
| US5268182A (en) * | 1988-06-24 | 1993-12-07 | Abbott Laboratories | Sustained-release drug dosage units of terazosin |
| US5612059A (en) * | 1988-08-30 | 1997-03-18 | Pfizer Inc. | Use of asymmetric membranes in delivery devices |
| US5084287A (en) * | 1990-03-15 | 1992-01-28 | Warner-Lambert Company | Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat |
| ATE118345T1 (de) * | 1990-08-07 | 1995-03-15 | Pfizer | Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen. |
| CA2106494A1 (en) * | 1991-03-18 | 1992-09-19 | James W. Young | Composition and method containing optically pure (s) metoprolol |
| WO1992020326A1 (en) * | 1991-05-20 | 1992-11-26 | Marion Laboratories, Inc. | Multi-layered controlled release formulation |
| IT1252185B (it) * | 1991-12-11 | 1995-06-05 | Therapicon Srl | Preparazioni farmaceutiche a liberazione programmata |
| US7740881B1 (en) | 1993-07-01 | 2010-06-22 | Purdue Pharma Lp | Method of treating humans with opioid formulations having extended controlled release |
| US5399358A (en) * | 1993-11-12 | 1995-03-21 | Edward Mendell Co., Inc. | Sustained release formulations for 24 hour release of metroprolol |
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| SE9702338D0 (sv) * | 1997-06-18 | 1997-06-18 | Astra Ab | An analytical method and industrial process including the same |
| SE9802537D0 (sv) * | 1998-07-13 | 1998-07-13 | Astra Ab | Method for controlling a coating process |
| UA73092C2 (uk) * | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
| DE19842753A1 (de) * | 1998-09-18 | 2000-03-23 | Bayer Ag | Agitationsunabhängige pharmazeutische Retardzubereitungen und Verfahren zu ihrer Herstellung |
| US8236352B2 (en) | 1998-10-01 | 2012-08-07 | Alkermes Pharma Ireland Limited | Glipizide compositions |
| US8293277B2 (en) | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
| EP2266542A3 (en) * | 1998-10-01 | 2013-07-31 | Elan Pharma International Limited | Controlled release nanoparticulate compositions |
| DE19848651C1 (de) * | 1998-10-22 | 2000-01-27 | Porsche Ag | Tülle für ein Kabelbündel |
| DE59905248D1 (de) * | 1999-01-29 | 2003-05-28 | Disphar Int Bv | Pharmazeutische zusammensetzungen |
| FR2802424B1 (fr) * | 1999-12-17 | 2002-02-15 | Adir | Comprime matriciel permettant la liberation prolongee de trimetazidine apres administration par voie orale |
| US7198795B2 (en) | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
| GB0025208D0 (en) | 2000-10-13 | 2000-11-29 | Euro Celtique Sa | Delayed release pharmaceutical formulations |
| SE0100200D0 (sv) * | 2001-01-24 | 2001-01-24 | Astrazeneca Ab | New film coating |
| US6610326B2 (en) * | 2001-02-16 | 2003-08-26 | Andrx Corporation | Divalproex sodium tablets |
| US20040105886A1 (en) * | 2001-02-16 | 2004-06-03 | Chih-Ming Chen | Divalproex sodium tablets |
| SE0100824D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method III to obtain microparticles |
| US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
| RU2190397C1 (ru) * | 2001-10-25 | 2002-10-10 | Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" | Фармацевтическая композиция, содержащая кардиоселективный бета-адреноблокатор, и способ ее получения |
| EP1355633B1 (en) * | 2001-12-19 | 2005-01-19 | AstraZeneca AB | NEW FILM COATING containing an ethyl acrylate/methyl methacrylate copolymer and polyvinyl acetate |
| EP1471887B1 (en) | 2002-02-04 | 2010-04-21 | Elan Pharma International Ltd. | Nanoparticulate compositions having lysozyme as a surface stabilizer |
| EP1499295A4 (en) * | 2002-04-05 | 2006-04-05 | Penwest Pharmaceuticals Co | EXTENDED RELEASE METOPROLOL FORMULATIONS |
| SE0201110D0 (sv) * | 2002-04-12 | 2002-04-12 | Astrazeneca Ab | New film coating |
| US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
| US7217300B2 (en) | 2003-06-27 | 2007-05-15 | Delphi Technologies, Inc. | Method and apparatus for gasketing a fuel cell |
| US7314640B2 (en) * | 2003-07-11 | 2008-01-01 | Mongkol Sriwongjanya | Formulation and process for drug loaded cores |
| US20050032879A1 (en) * | 2003-08-07 | 2005-02-10 | Temple Okarter | Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases |
| CA2556220A1 (en) * | 2004-02-11 | 2005-08-25 | Athpharma Limited | Chronotherapeutic compositions and methods of their use |
| US20060105044A1 (en) | 2004-05-20 | 2006-05-18 | Singh Bramah N | Sustained release formulations of sotalol |
| US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
| US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| NZ589750A (en) | 2004-10-21 | 2012-07-27 | Aptalis Pharmatech Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
| US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
| US8920837B2 (en) * | 2005-07-01 | 2014-12-30 | Rubicon Research Private Limited | Sustained release dosage form |
| US20070009589A1 (en) * | 2005-07-07 | 2007-01-11 | Kandarapu Raghupathi | Extended release compositions |
| WO2007010501A2 (en) * | 2005-07-22 | 2007-01-25 | Ranbaxy Laboratories Limited | A pharmaceutical composition comprising a combination of beta blocker and an ace inhibitor |
| US20070053983A1 (en) * | 2005-09-06 | 2007-03-08 | Girish Jain | Extended release compositions of metoprolol succinate |
| US20070092573A1 (en) * | 2005-10-24 | 2007-04-26 | Laxminarayan Joshi | Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist |
| DE102005060393A1 (de) * | 2005-12-16 | 2007-06-21 | Add Advanced Drug Delivery Technologies Ltd. | Orales Präparat mit kontrollierter Freisetzung |
| US8691272B2 (en) * | 2005-12-30 | 2014-04-08 | Intelgenx Corp. | Multilayer tablet |
| US20090068260A1 (en) * | 2006-02-24 | 2009-03-12 | Tomer Gold | Beta-1-selective adrenoceptor blocking agent compositions and methods for their preparation |
| US20070202172A1 (en) * | 2006-02-24 | 2007-08-30 | Tomer Gold | Metoprolol succinate E.R. tablets and methods for their preparation |
| CA2657202A1 (en) * | 2006-07-28 | 2008-01-31 | Farmaprojects, S.A. | Extended release pharmaceutical formulation of metoprolol and process for its preparation |
| US20080107726A1 (en) * | 2006-11-01 | 2008-05-08 | Pramod Kharwade | Compositions comprising beta-adrenergic receptor antagonists and diuretics |
| US20080187579A1 (en) * | 2007-02-01 | 2008-08-07 | Pavan Bhat | Extended-release dosage form |
| WO2008103245A2 (en) * | 2007-02-23 | 2008-08-28 | Glatt Air Techniques, Inc. | Method of determining the weight of the coating to be applied to form a controlled release dosage form |
| DK2255791T3 (da) * | 2009-04-03 | 2012-03-05 | Zaklady Farmaceutyczne Polpharma Sa | Forlænget-frigivelse-farmaceutisk sammensætning omfattende metoprololsuccinat |
| CN102958515A (zh) | 2009-12-02 | 2013-03-06 | 阿普塔利斯制药有限公司 | 非索非那定微胶囊及含有非索非那定微胶囊的组合物 |
| US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
| US20110136815A1 (en) | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| CN102670539A (zh) * | 2011-03-14 | 2012-09-19 | 北京天衡药物研究院 | 琥珀酸美托洛尔渗透泵控释片 |
| CN105007902A (zh) | 2013-02-13 | 2015-10-28 | 赢创罗姆有限公司 | 包含大量的两种丸粒的多颗粒药物组合物 |
| EP2968164A4 (en) * | 2013-03-15 | 2016-10-26 | David Barnes | COMPOSITIONS AND METHODS OF ADMINISTRATION TO DYSPHAGIA SUBJECTS |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH532038A (de) * | 1970-05-25 | 1972-12-31 | Ciba Geigy Ag | Verfahren zur Herstellung von neuen Cycloheptenderivaten |
| US3951821A (en) * | 1972-07-14 | 1976-04-20 | The Dow Chemical Company | Disintegrating agent for tablets |
| US4036227A (en) | 1973-04-25 | 1977-07-19 | Alza Corporation | Osmotic releasing device having a plurality of release rate patterns |
| US4123382A (en) * | 1973-05-25 | 1978-10-31 | Merck & Co., Inc. | Method of microencapsulation |
| DE2336218C3 (de) * | 1973-07-17 | 1985-11-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Orale Arzneiform |
| SE418247B (sv) * | 1975-11-17 | 1981-05-18 | Haessle Ab | Sett att framstella kroppar med reglerad frigoring av en aktiv komponent |
| US4291016A (en) * | 1976-07-27 | 1981-09-22 | Sandoz Ltd. | Enteric coated mixture of 4-(2-hydroxy-3-isopropylamino-propoxy) indole and sodium lauryl sulphate |
| GB1542414A (en) * | 1976-08-19 | 1979-03-21 | Standard Telephones Cables Ltd | Arrangements for the controlled release of biologically active materials |
| DE2642032C2 (de) * | 1976-09-18 | 1987-04-30 | Rupprecht, Herbert, Prof. Dr., 8400 Regensburg | Verfahren zur Inkorporierung von Wirkstoffen in siliciumdioxidhaltige Trägermaterialien und eine siliciumdioxidhaltige Zubereitung |
| GB1576376A (en) * | 1977-03-30 | 1980-10-08 | Benzon As Alfred | Multiple-unit drug dose |
| US4256108A (en) * | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| SE426548B (sv) * | 1978-12-05 | 1983-01-31 | Haessle Ab | Fast farmaceutisk beredning innehallande en terapeutiskt effektiv hjertglykosid och en polymer |
| US4309406A (en) * | 1979-07-10 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
| US4309404A (en) * | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
| CH655658B (is) * | 1980-09-18 | 1986-05-15 | ||
| US4439195A (en) * | 1980-10-14 | 1984-03-27 | Alza Corporation | Theophylline therapy |
| US4326525A (en) * | 1980-10-14 | 1982-04-27 | Alza Corporation | Osmotic device that improves delivery properties of agent in situ |
| IT1144911B (it) * | 1981-03-19 | 1986-10-29 | Pharmatec Spa | Composizione farmaceutica a rilascio controllato contenente ibuprofen |
| GB2098867B (en) * | 1981-05-21 | 1984-10-24 | Wyeth John & Brother Ltd | Sustained release pharmaceutical composition |
| US4484921A (en) * | 1982-02-01 | 1984-11-27 | Alza Corporation | Theophylline therapy utilizing osmotic delivery |
| US4434153A (en) * | 1982-03-22 | 1984-02-28 | Alza Corporation | Drug delivery system comprising a reservoir containing a plurality of tiny pills |
| US4449983A (en) * | 1982-03-22 | 1984-05-22 | Alza Corporation | Simultaneous delivery of two drugs from unit delivery device |
| US4642233A (en) * | 1982-03-22 | 1987-02-10 | Alza Corporation | Gastrointestinal drug delivery system comprising a hydrogel reservoir containing a plurality of tiny pills |
| US4649043A (en) * | 1982-03-22 | 1987-03-10 | Alza Corporation | Drug delivery system for delivering a plurality of tiny pills in the gastrointestinal tract |
| US4415547A (en) * | 1982-06-14 | 1983-11-15 | Sterling Drug Inc. | Sustained-release pharmaceutical tablet and process for preparation thereof |
| ZA836627B (en) * | 1982-10-08 | 1984-05-30 | Verex Lab | Constant release rate solid oral dosage formulation of pharmaceutical compounds having a high degree of water solubility |
| US4681583A (en) * | 1982-12-20 | 1987-07-21 | Alza Corporation | System for dispersing drug in biological environment |
| US4578075A (en) * | 1982-12-20 | 1986-03-25 | Alza Corporation | Delivery system housing a plurality of delivery devices |
| PH18946A (en) * | 1983-04-21 | 1985-11-14 | Elan Corp Plc | Controlled absorption pharmaceutical composition |
| AU581177B2 (en) * | 1983-05-31 | 1989-02-16 | Choong-Gook Jang | Dry direct compression compositions for controlled release dosage forms |
| GB2146531B (en) * | 1983-09-15 | 1987-04-29 | Stc Plc | Controlled release system |
| SE457505B (sv) * | 1984-01-10 | 1989-01-09 | Lejus Medical Ab | Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning |
| AU571312B2 (en) * | 1984-02-10 | 1988-04-14 | Nycomed Danmark A/S | Diffusion coated multiple-units dosage form |
| IT1206166B (it) * | 1984-07-26 | 1989-04-14 | Sigma Tau Ind Farmaceuti | Dispositivo per rilasciare una sostanza in un fluido di dissoluzione con cinetica di ordine zero e procedimento per la sua preparazione |
| GB2159715B (en) * | 1984-06-04 | 1988-05-05 | Sterwin Ag | Pharmaceutical composition in sustained release unit dose form and process for its preparation |
| NL8500724A (nl) * | 1985-03-13 | 1986-10-01 | Univ Groningen | Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan. |
-
1985
- 1985-10-11 SE SE8504721A patent/SE455836B/sv not_active IP Right Cessation
-
1986
- 1986-09-09 ZA ZA869860A patent/ZA869860B/xx unknown
- 1986-09-18 IE IE249286A patent/IE59053B1/en not_active IP Right Cessation
- 1986-09-25 GB GB8623048A patent/GB2181348B/en not_active Expired
- 1986-09-25 PH PH34289A patent/PH22277A/en unknown
- 1986-09-26 AU AU63171/86A patent/AU588630B2/en not_active Expired
- 1986-09-26 NZ NZ217696A patent/NZ217696A/xx unknown
- 1986-10-02 ES ES86850330T patent/ES2003863B3/es not_active Expired - Lifetime
- 1986-10-02 AT AT86850330T patent/ATE65391T1/de not_active IP Right Cessation
- 1986-10-02 DE DE8686850330T patent/DE3680450D1/de not_active Expired - Lifetime
- 1986-10-02 DE DE198686850330T patent/DE220143T1/de active Pending
- 1986-10-02 EP EP86850330A patent/EP0220143B1/en not_active Expired - Lifetime
- 1986-10-07 NO NO863997A patent/NO172276C/no unknown
- 1986-10-07 DK DK478186A patent/DK165939C/da not_active IP Right Cessation
- 1986-10-08 DZ DZ860208A patent/DZ994A1/fr active
- 1986-10-09 JP JP61239424A patent/JPH0759506B2/ja not_active Expired - Lifetime
- 1986-10-09 PT PT83509A patent/PT83509B/pt unknown
- 1986-10-10 HU HU864249A patent/HU197839B/hu unknown
- 1986-10-10 FI FI864108A patent/FI88579C/fi not_active IP Right Cessation
- 1986-10-10 UA UA4028342A patent/UA26211A/uk unknown
- 1986-10-10 KR KR1019860008481A patent/KR940000100B1/ko not_active Expired - Lifetime
- 1986-10-10 SU SU864028342A patent/SU1760969A3/ru active
- 1986-10-10 DD DD86295170A patent/DD259789A5/de unknown
- 1986-10-10 PL PL1986261802A patent/PL261802A1/xx unknown
- 1986-10-10 IS IS3151A patent/IS1529B/is unknown
- 1986-10-11 CN CN86106588A patent/CN1023293C/zh not_active Expired - Lifetime
-
1989
- 1989-02-14 US US07/310,489 patent/US4957745A/en not_active Expired - Lifetime
- 1989-06-22 GR GR89300059T patent/GR890300059T1/el unknown
-
1991
- 1991-08-19 GR GR91401214T patent/GR3002571T3/el unknown
- 1991-09-10 UA UA5001493A patent/UA39162C2/uk unknown
- 1991-09-10 RU SU915001493A patent/RU2072840C1/ru active
- 1991-11-08 SG SG952/91A patent/SG95291G/en unknown
- 1991-12-12 HK HK1017/91A patent/HK101791A/xx not_active IP Right Cessation
-
1992
- 1992-07-10 CY CY1616A patent/CY1616A/en unknown
-
1993
- 1993-06-28 LV LVP-93-685A patent/LV10913B/en unknown
- 1993-06-30 LV LV930884A patent/LV10914A/xx unknown
- 1993-12-28 LT LTIP1680A patent/LTIP1680A/xx not_active Application Discontinuation
- 1993-12-28 LT LTIP1679A patent/LT3951B/lt not_active IP Right Cessation
-
1996
- 1996-07-17 LV LV960258A patent/LV5751B4/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK165939C (da) | Metropololpraeparat med styret, kontinuerlig afgivelse af det aktive stof, farmaceutisk praeparat indeholdende samme og fremgangsmaade til fremstilling af metropololpraeparatet samt anvendelse af metropololpraeparatet til fremstilling af et farmaceutisk praeparat til behandling af kardiovaskulaere lidelser | |
| SE8504720L (sv) | Ny lekemedelsberedning | |
| DK153948C (da) | Analogifremgangsmaade til fremstilling af vandoploeselige associationsprodukter af (+)-katekin med en aminosyre og eventuelt tillige en anden syre | |
| DK241183A (da) | Forbindelser med antineoplastisk aktivitet, fremgangsmaade til fremstilling deraf og farmaceutiske midler derfra | |
| PH10345A (en) | N-methyl-d-glucamine of 2(2'-methyl-3'-trifluoro-methylanilino nicotinic acid,pharmaceutical composition containing the same and method of use thereof | |
| PH13780A (en) | N-tetrahydrofurfuryl-noroxynorphones,their salts,and analgesic compositions and methods employing them | |
| EP0079536A3 (en) | Modified polyamines, process for the preparation of these polyamines and their use in the production of polyurethanes | |
| DK145906C (da) | Analogifremgangsmaade til fremstilling af n,n-dimethyl-trans-2-(m-halogenphenyl)bicyclo(2,2,2)oct-3-yl-methylamin og syreadditionssalte deraf | |
| PH13791A (en) | Propargyl-substituted 2-phenylamino-2-imidazolines and salts thereof,their pharmaceutical composition and method of use | |
| MY102184A (en) | New drug preparation with controlled release of the active compound, a method for the manufacture thereof and the use of the new preparation | |
| FI812439A7 (fi) | Alkyylivirtsa-ainejohdannaiset, joita käytetään rasva-aineenvaihdunnan sairauksien hoitamiseen, menetelmä niniiden valmistamiseksi, niiden käyttö lääkeaineissa hoidettaessa rasvaainevaihduntahäiriöitä, niitä sisältävät lääkeaineet ja menetelmä lääk | |
| IE45257L (en) | 11-OXO-PYRIDO [2,1-b] QUINAZOLINE-2-CARBOXYLIC ACID AND¹ESTERS AND SALTS THEREOF |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |