DK1670779T3 - Fremgangsmåde til fremstilling af 3-methylamino-1-(thien-2-yl)-propan-1-ol - Google Patents

Fremgangsmåde til fremstilling af 3-methylamino-1-(thien-2-yl)-propan-1-ol

Info

Publication number: DK1670779T3
Authority: DK; Denmark
Prior art keywords: thien; propan; methylamino; preparation; enzymes
Prior art date: 2003-10-01

Application number

DK04765718.4T

Other languages

English (en)

Inventor

Rainer Stuermer

Maria Kesseler

Bernhard Hauer

Thomas Friedrich

Michael Breuer

Original Assignee

Basf Se

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-01

Filing date

2004-09-30

Publication date

2011-02-28

2004-09-30 Application filed by Basf Se filed Critical Basf Se

2011-02-28 Application granted granted Critical

2011-02-28 Publication of DK1670779T3 publication Critical patent/DK1670779T3/da

Links

YEJVVFOJMOHFRL-UHFFFAOYSA-N 3-(methylamino)-1-thiophen-2-ylpropan-1-ol Chemical compound CNCCC(O)C1=CC=CS1 YEJVVFOJMOHFRL-UHFFFAOYSA-N 0.000 title abstract 2
102000004190 Enzymes Human genes 0.000 abstract 2
108090000790 Enzymes Proteins 0.000 abstract 2
150000007523 nucleic acids Chemical group 0.000 abstract 2
239000013598 vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK04765718.4T 2003-10-01 2004-09-30 Fremgangsmåde til fremstilling af 3-methylamino-1-(thien-2-yl)-propan-1-ol DK1670779T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10345772A DE10345772A1 (de)	2003-10-01	2003-10-01	Verfahren zur Herstellung von 3-Methylamino-1-(thien-2-yl)-propan-1-ol
PCT/EP2004/010939 WO2005033094A2 (de)	2003-10-01	2004-09-30	Verfahren zur herstellung von 3-methylamino-1-(thien-2-yl)-propan-1-ol

Publications (1)

Publication Number	Publication Date
DK1670779T3 true DK1670779T3 (da)	2011-02-28

Family

ID=34353261

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04765718.4T DK1670779T3 (da)	2003-10-01	2004-09-30	Fremgangsmåde til fremstilling af 3-methylamino-1-(thien-2-yl)-propan-1-ol

Country Status (11)

Country	Link
US (1)	US7498448B2 (da)
EP (1)	EP1670779B1 (da)
JP (2)	JP2007533628A (da)
CN (1)	CN1860110B (da)
AT (1)	ATE489377T1 (da)
DE (2)	DE10345772A1 (da)
DK (1)	DK1670779T3 (da)
ES (1)	ES2357115T3 (da)
PT (1)	PT1670779E (da)
SI (1)	SI1670779T1 (da)
WO (1)	WO2005033094A2 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102004022686A1 (de) *	2004-05-05	2005-11-24	Basf Ag	Verfahren zur Herstellung optisch aktiver Alkohole
DE102005010804A1 (de) *	2005-03-07	2006-09-14	Basf Ag	Verfahren zur Herstellung optisch aktiver Alkohole
DE102005044736A1 (de) *	2005-09-19	2007-03-22	Basf Ag	Neue Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von optisch aktiven Alkanolen
DE102005062662A1 (de)	2005-12-23	2007-06-28	Basf Ag	Verfahren zur Herstellung optisch aktiver Alkohole
DE102005062661A1 (de) *	2005-12-23	2007-08-16	Basf Ag	Verfahren zur Herstellung von optisch aktivem (1S)-3-Chlor-(-thien-2-yl)-propan-1-ol
US20100280093A1 (en)	2006-07-03	2010-11-04	Ranbaxy Laboratories Limited	Process for the preparation enantiomerically pure salts of n-methyl-3-(1-naphthaleneoxy)-3-(2-thienyl)propanamine
CN101528917B (zh)	2006-10-02	2015-07-29	科德克希思公司	用于制备立体异构纯的他汀类及其合成中间体的组合物和方法
KR101502634B1 (ko)	2007-02-08	2015-03-16	코덱시스, 인코포레이티드	케토 환원 효소 및 이의 용도
EP2195443B1 (en)	2007-08-24	2015-01-07	Codexis, Inc.	Improved ketoreductase polypeptides for the stereoselective production of (r)-3-hydroxythiolane
CN101855342B (zh)	2007-09-13	2013-07-10	科德克希思公司	用于还原苯乙酮的酮还原酶多肽
CN101889081B (zh)	2007-09-28	2014-06-18	科德克希思公司	酮还原酶多肽及其用途
JP5646328B2 (ja)	2007-10-01	2014-12-24	コデクシス，インコーポレイテッド	アゼチジノンの生産のためのケトレダクターゼポリペプチド
EP2060559A1 (en) *	2007-11-19	2009-05-20	Cadila Pharmaceuticals Limited	Process for the preparation of enantiomerically pure 3-hydroxy-3-arylpropylamines and their optical stereoisomers
WO2010025287A2 (en)	2008-08-27	2010-03-04	Codexis, Inc.	Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
ES2560459T3 (es)	2008-08-27	2016-02-19	Codexis, Inc.	Polipéptidos cetorreductasa para la producción de una 3-aril-3-hidroxipropanamina a partir de una 3-aril-3-cetopropanamina
SG10201404330VA (en)	2008-08-29	2014-10-30	Codexis Inc	Ketoreductase Polypeptides For The Stereoselective Production Of (4S)-3[(5S)-5(4-Fluorophenyl)-5-Hydroxypentanoyl]-4-Phenyl-1,3-Oxazolidin-2-One
JP2012511922A (ja)	2008-12-17	2012-05-31	ビーエーエスエフソシエタス・ヨーロピア	デュロキセチンアルコールを製造するための改良型生体触媒
EP2226386A1 (de)	2009-03-05	2010-09-08	IEP GmbH	Verfahren zur stereoselektiven enzymatischen Reduktion von Ketoverbindungen
WO2011022548A2 (en)	2009-08-19	2011-02-24	Codexis, Inc.	Ketoreductase polypeptides for the preparation of phenylephrine
EP2566497B1 (en)	2010-05-04	2015-07-29	Codexis, Inc.	Biocatalysts for ezetimibe synthesis
EP2697662B1 (en) *	2011-04-13	2018-06-06	Codexis, Inc.	Biocatalytic process for preparing eslicarbazepine and analogs thereof
CN107746861B (zh) *	2017-11-20	2020-06-23	浙江工业大学	一种(r)-1-(2-三氟甲基苯基)乙醇的生物制备方法
CN117737149B (zh) *	2024-02-20	2024-05-07	山东君泰药业有限公司	一种酶催化合成高纯度s-玻色因的方法
WO2026083999A1 (ja) *	2024-10-16	2026-04-23	株式会社日本触媒	イソプロパノール生産能を有するコリネバクテリウム属細菌、及び微生物を用いたイソプロパノールの製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3803173A (en) *	1971-04-26	1974-04-09	Degussa	3-(3-(1-(4-hydroxyphenyl)-1-hydroxypropyl-(2)-amino)-propionyl)-thiophene
KR880007433A (ko)	1986-12-22	1988-08-27	메리 앤 터커	3-아릴옥시-3-치환된 프로판아민
CA2042346A1 (en)	1990-05-17	1991-11-18	Michael Alexander Staszak	Chiral synthesis of 1-aryl-3-aminopropan-1-ols
US5362886A (en) *	1993-10-12	1994-11-08	Eli Lilly And Company	Asymmetric synthesis
DE19857302C2 (de) *	1998-12-14	2000-10-26	Forschungszentrum Juelich Gmbh	Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren, deren Salze und Ester
EP1194582A1 (de) *	1999-07-09	2002-04-10	Forschungszentrum Jülich Gmbh	Verfahren zur reduktion von keto-carbonsäuren und deren estern
DE19931847A1 (de) *	1999-07-09	2001-01-11	Basf Ag	Immobilisierte Lipase
SI20642A (sl) *	1999-12-03	2002-02-28	Kaneka Corporation	Nova karbonil-reduktaza, gen le-te in postopek za uporabo le-teh
DE10019380A1 (de)	2000-04-19	2001-10-25	Basf Ag	Verfahren zur Herstellung von kovalent gebundenen biologisch aktiven Stoffen an Polyurethanschaumstoffen sowie Verwendung der geträgerten Polyurethanschaumstoffe für chirale Synthesen
JP4818507B2 (ja) *	2000-11-21	2011-11-16	三菱レイヨン株式会社	光学活性３−キヌクリジノールの製造法
JP2002165393A (ja) *	2000-11-27	2002-06-07	Toshiba Tec Corp	ブラシレスモータ
JP4913296B2 (ja) *	2001-09-21	2012-04-11	三菱レイヨン株式会社	光学活性アルコール及びその製造方法
WO2003031636A1 (en) *	2001-10-05	2003-04-17	Kaneka Corporation	Process for production of optically active 3-hydroxy- pentanenitrile
JP2003199595A (ja) *	2001-10-24	2003-07-15	Daicel Chem Ind Ltd	光学活性マンデル酸誘導体の製造方法
JP2003192681A (ja)	2001-12-27	2003-07-09	Mitsubishi Rayon Co Ltd	（ｓ）−３−クロロ−１−（２−チエニル）−１−プロパノール及び（ｓ）−３−ｎ−メチルアミノ−１−（２−チエニル）−１−プロパノールの製造方法
DE10248480A1 (de)	2002-10-17	2004-05-06	Consortium für elektrochemische Industrie GmbH	Verfahren zur Herstellung von Thienyl-substituierten sekundären Aminoalkoholen
DE10248479A1 (de)	2002-10-17	2004-05-06	Consortium für elektrochemische Industrie GmbH	Verfahren zur Herstellung von Thienyl-substituierten sekundären Aminoalkoholen

2003
- 2003-10-01 DE DE10345772A patent/DE10345772A1/de not_active Withdrawn
2004
- 2004-09-30 CN CN2004800281086A patent/CN1860110B/zh not_active Expired - Fee Related
- 2004-09-30 EP EP04765718A patent/EP1670779B1/de not_active Expired - Lifetime
- 2004-09-30 PT PT04765718T patent/PT1670779E/pt unknown
- 2004-09-30 JP JP2006530058A patent/JP2007533628A/ja active Pending
- 2004-09-30 US US10/573,130 patent/US7498448B2/en not_active Expired - Fee Related
- 2004-09-30 DE DE502004011932T patent/DE502004011932D1/de not_active Expired - Lifetime
- 2004-09-30 SI SI200431560T patent/SI1670779T1/sl unknown
- 2004-09-30 WO PCT/EP2004/010939 patent/WO2005033094A2/de not_active Ceased
- 2004-09-30 DK DK04765718.4T patent/DK1670779T3/da active
- 2004-09-30 AT AT04765718T patent/ATE489377T1/de active
- 2004-09-30 ES ES04765718T patent/ES2357115T3/es not_active Expired - Lifetime
2011
- 2011-01-14 JP JP2011005361A patent/JP2011142908A/ja active Pending

Also Published As

Publication number	Publication date
JP2007533628A (ja)	2007-11-22
PT1670779E (pt)	2010-12-16
US20070083055A1 (en)	2007-04-12
US7498448B2 (en)	2009-03-03
EP1670779A2 (de)	2006-06-21
CN1860110A (zh)	2006-11-08
JP2011142908A (ja)	2011-07-28
CN1860110B (zh)	2012-03-21
WO2005033094A3 (de)	2005-11-24
DE502004011932D1 (de)	2011-01-05
ES2357115T3 (es)	2011-04-18
SI1670779T1 (sl)	2011-01-31
DE10345772A1 (de)	2005-04-21
ATE489377T1 (de)	2010-12-15
EP1670779B1 (de)	2010-11-24
WO2005033094A2 (de)	2005-04-14

Publication	Publication Date	Title
DE502004011932D1 (de)	2011-01-05	Verfahren zur herstellung von 3-methylamino-1-(thien-2-yl)-propan-1-ol
MX2021004898A (es)	2021-06-18	Enzima de crispr/cas12f y sistema novedosos.
ATE530643T1 (de)	2011-11-15	Säureaktive fungale protease
DK1208205T3 (da)	2007-02-05	Fremgangsmåder til frembringelse af L-aminosyrer ved hjælp af en forögelse af cellulært NADPH
DK1266011T3 (da)	2010-07-26	Svampetranskriptionsaktivator, der er anvendelig i fremgangsmåder til fremstilling af polypeptider
WO2005069762A8 (en)	2011-08-18	Bacillus licheniformis chromosome
WO2002086144A3 (en)	2003-12-04	Compositions and methods for recombinational cloning of nucleic acid molecules
EA201170715A1 (ru)	2012-03-30	Вектор, содержащий множественные гомологичные нуклеотидные последовательности
AU2003258187A8 (en)	2004-02-25	Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
DK1675956T3 (da)	2010-11-22	Minimal DNA-sekvens, der virksom som chromatinisolator, og dennes anvendelse til proteinekspression
DK1242601T3 (da)	2005-06-13	Trichoderma reesei-xylanase
DK1157100T3 (da)	2006-05-29	Oxaloacetathydrolase-defekte svampeværtsceller
ATE532861T1 (de)	2011-11-15	Expressionsvektor
WO2003064622A3 (en)	2003-11-27	Aggrecanase molecules
DE502005007057D1 (de)	2009-05-20	Verfahren zur herstellung von (s)-butan-2-ol
DK1756273T3 (da)	2010-02-01	Signalpeptid til frembringelse af et polypeptid
DK1226236T3 (da)	2006-06-19	Polypeptider, der har glucanotransferase-aktivitet, og nucleinsyrer, som koder disse
EA201100583A1 (ru)	2011-12-30	СПОСОБ ПОЛУЧЕНИЯ ε-КАПРОЛАКТАМА ИЗ N-АЦИЛ-6-АМИНОКАПРОНОВОЙ КИСЛОТЫ
WO2004085651A3 (en)	2005-01-20	Pantolactone hydrolase
ATE414905T1 (de)	2008-12-15	Diabetesmodell
WO2002033093A3 (en)	2003-02-27	Aggrecanase molecules
WO2003064597A3 (en)	2004-06-03	Aggrecanase molecules
EA200702009A1 (ru)	2008-02-28	Усовершенствованный способ экспрессирующего клонирования в клетке-хозяине
WO2003004607A3 (en)	2003-07-31	Aggrecanase molecules
WO2002077009A3 (en)	2003-01-09	Polypeptides having gamma-glutamyl transpeptidase activity and nucleic acids encoding same