DK1670779T3 - Fremgangsmåde til fremstilling af 3-methylamino-1-(thien-2-yl)-propan-1-ol - Google Patents

Fremgangsmåde til fremstilling af 3-methylamino-1-(thien-2-yl)-propan-1-ol

Info

Publication number
DK1670779T3
DK1670779T3 DK04765718.4T DK04765718T DK1670779T3 DK 1670779 T3 DK1670779 T3 DK 1670779T3 DK 04765718 T DK04765718 T DK 04765718T DK 1670779 T3 DK1670779 T3 DK 1670779T3
Authority
DK
Denmark
Prior art keywords
thien
propan
methylamino
preparation
enzymes
Prior art date
Application number
DK04765718.4T
Other languages
English (en)
Inventor
Rainer Stuermer
Maria Kesseler
Bernhard Hauer
Thomas Friedrich
Michael Breuer
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Application granted granted Critical
Publication of DK1670779T3 publication Critical patent/DK1670779T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK04765718.4T 2003-10-01 2004-09-30 Fremgangsmåde til fremstilling af 3-methylamino-1-(thien-2-yl)-propan-1-ol DK1670779T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10345772A DE10345772A1 (de) 2003-10-01 2003-10-01 Verfahren zur Herstellung von 3-Methylamino-1-(thien-2-yl)-propan-1-ol
PCT/EP2004/010939 WO2005033094A2 (de) 2003-10-01 2004-09-30 Verfahren zur herstellung von 3-methylamino-1-(thien-2-yl)-propan-1-ol

Publications (1)

Publication Number Publication Date
DK1670779T3 true DK1670779T3 (da) 2011-02-28

Family

ID=34353261

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04765718.4T DK1670779T3 (da) 2003-10-01 2004-09-30 Fremgangsmåde til fremstilling af 3-methylamino-1-(thien-2-yl)-propan-1-ol

Country Status (11)

Country Link
US (1) US7498448B2 (da)
EP (1) EP1670779B1 (da)
JP (2) JP2007533628A (da)
CN (1) CN1860110B (da)
AT (1) ATE489377T1 (da)
DE (2) DE10345772A1 (da)
DK (1) DK1670779T3 (da)
ES (1) ES2357115T3 (da)
PT (1) PT1670779E (da)
SI (1) SI1670779T1 (da)
WO (1) WO2005033094A2 (da)

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DE102005010804A1 (de) * 2005-03-07 2006-09-14 Basf Ag Verfahren zur Herstellung optisch aktiver Alkohole
DE102005044736A1 (de) * 2005-09-19 2007-03-22 Basf Ag Neue Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von optisch aktiven Alkanolen
DE102005062661A1 (de) * 2005-12-23 2007-08-16 Basf Ag Verfahren zur Herstellung von optisch aktivem (1S)-3-Chlor-(-thien-2-yl)-propan-1-ol
DE102005062662A1 (de) * 2005-12-23 2007-06-28 Basf Ag Verfahren zur Herstellung optisch aktiver Alkohole
EP2044049A2 (en) 2006-07-03 2009-04-08 Ranbaxy Laboratories Limited Process for the preparation of enantiomerically pure salts of n-methyl- 3 -( 1-naph-thaleneoxy)- 3 - (-2-thienyl) propanamine
WO2008042876A2 (en) 2006-10-02 2008-04-10 Codexis, Inc. Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor
CN101627116B (zh) 2007-02-08 2013-07-10 科德克希思公司 酮还原酶及其用途
JP2010536385A (ja) 2007-08-24 2010-12-02 コデクシス, インコーポレイテッド (r)−3−ヒドロキシチオランの立体選択的生成のための改善されたケトレダクターゼポリペプチド
KR101586503B1 (ko) 2007-09-13 2016-01-18 코덱시스, 인코포레이티드 아세토페논의 환원을 위한 케토리덕타제 폴리펩티드
CN101889081B (zh) 2007-09-28 2014-06-18 科德克希思公司 酮还原酶多肽及其用途
HUE027683T2 (en) 2007-10-01 2016-10-28 Codexis Inc Ketoreductase polypeptides for the production of azetidinone
EP2060559A1 (en) * 2007-11-19 2009-05-20 Cadila Pharmaceuticals Limited Process for the preparation of enantiomerically pure 3-hydroxy-3-arylpropylamines and their optical stereoisomers
WO2010025287A2 (en) 2008-08-27 2010-03-04 Codexis, Inc. Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
WO2010025238A2 (en) 2008-08-27 2010-03-04 Codexis, Inc. Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
SI2329014T1 (sl) 2008-08-29 2015-01-30 Codexis, Inc. Polipeptidi ketoreduktaze za stereoselektivno produkcijo (4s)-3(5s)-5(4-fluorofenil)-5-hidroksipentanoil)-4-fenil-1,3-oksazolidin -2-ona
CN102317450A (zh) 2008-12-17 2012-01-11 巴斯夫欧洲公司 用于制备度洛西汀(duloxetine)醇之改良生物催化剂
EP2226386A1 (de) 2009-03-05 2010-09-08 IEP GmbH Verfahren zur stereoselektiven enzymatischen Reduktion von Ketoverbindungen
WO2011022548A2 (en) 2009-08-19 2011-02-24 Codexis, Inc. Ketoreductase polypeptides for the preparation of phenylephrine
HUE026367T2 (en) 2010-05-04 2016-06-28 Codexis Inc Biocatalysts for ezetimibe synthesis
HUE038800T2 (hu) * 2011-04-13 2018-11-28 Codexis Inc Biokatalitikus eljárás eszlikarbazepin és ennek analógjai elõállítására
CN107746861B (zh) * 2017-11-20 2020-06-23 浙江工业大学 一种(r)-1-(2-三氟甲基苯基)乙醇的生物制备方法
CN116410946A (zh) * 2023-01-20 2023-07-11 浙江工业大学 一种羰基还原酶LsCR突变体及其催化合成手性醇的应用
CN117737149B (zh) * 2024-02-20 2024-05-07 山东君泰药业有限公司 一种酶催化合成高纯度s-玻色因的方法
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JP4170221B2 (ja) * 2001-10-05 2008-10-22 株式会社カネカ 光学活性3−ヒドロキシペンタンニトリルの製造方法
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Also Published As

Publication number Publication date
EP1670779A2 (de) 2006-06-21
JP2011142908A (ja) 2011-07-28
WO2005033094A2 (de) 2005-04-14
PT1670779E (pt) 2010-12-16
SI1670779T1 (sl) 2011-01-31
CN1860110B (zh) 2012-03-21
JP2007533628A (ja) 2007-11-22
DE10345772A1 (de) 2005-04-21
ATE489377T1 (de) 2010-12-15
WO2005033094A3 (de) 2005-11-24
CN1860110A (zh) 2006-11-08
US20070083055A1 (en) 2007-04-12
US7498448B2 (en) 2009-03-03
ES2357115T3 (es) 2011-04-18
DE502004011932D1 (de) 2011-01-05
EP1670779B1 (de) 2010-11-24

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