DK1697752T3 - Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner - Google Patents

Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner

Info

Publication number
DK1697752T3
DK1697752T3 DK04820800T DK04820800T DK1697752T3 DK 1697752 T3 DK1697752 T3 DK 1697752T3 DK 04820800 T DK04820800 T DK 04820800T DK 04820800 T DK04820800 T DK 04820800T DK 1697752 T3 DK1697752 T3 DK 1697752T3
Authority
DK
Denmark
Prior art keywords
nanopores
assay chip
layer
support layer
membrane
Prior art date
Application number
DK04820800T
Other languages
English (en)
Inventor
Louis Tiefenauer
Karl Brander
Original Assignee
Scherrer Inst Paul
Leister Process Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherrer Inst Paul, Leister Process Tech filed Critical Scherrer Inst Paul
Application granted granted Critical
Publication of DK1697752T3 publication Critical patent/DK1697752T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DK04820800T 2003-12-23 2004-11-15 Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner DK1697752T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03029726 2003-12-23
EP04002119A EP1548444A1 (en) 2003-12-23 2004-01-31 An assay chip, and uses of said assay chip to determine molecular structures and functions
PCT/EP2004/012925 WO2005064342A1 (en) 2003-12-23 2004-11-15 An assay chip, and uses of said assay chip to determine molecular structures and functions

Publications (1)

Publication Number Publication Date
DK1697752T3 true DK1697752T3 (da) 2008-08-11

Family

ID=34553646

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04820800T DK1697752T3 (da) 2003-12-23 2004-11-15 Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner

Country Status (8)

Country Link
US (1) US8105820B2 (da)
EP (2) EP1548444A1 (da)
JP (1) JP4448142B2 (da)
CN (1) CN1902497B (da)
AT (1) ATE391916T1 (da)
DE (1) DE602004013042T2 (da)
DK (1) DK1697752T3 (da)
WO (1) WO2005064342A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102145259A (zh) * 2005-05-20 2011-08-10 水通道蛋白有限公司 用于过滤水的膜
KR100840619B1 (ko) 2006-12-19 2008-06-24 한양대학교 산학협력단 표면개질된 리포좀, 이를 포함하는 바이오칩 및 그제조방법
GB0724736D0 (en) 2007-12-19 2008-01-30 Oxford Nanolabs Ltd Formation of layers of amphiphilic molecules
WO2013154750A1 (en) * 2012-04-10 2013-10-17 The Trustees Of Columbia Unversity In The City Of New York Systems and methods for biological ion channel interfaces
JP5687683B2 (ja) * 2009-03-26 2015-03-18 トラスティーズ オブ ボストン ユニバーシティ ２種類の流体間の薄い固相界面上における撮像方法
CN102472742B (zh) * 2009-07-07 2015-07-22 西门子公司 作为生物芯片的传感器
JP5325735B2 (ja) * 2009-10-05 2013-10-23 エスケー化研株式会社 塗膜形成方法
CN102762746B (zh) 2010-02-23 2015-04-29 克里斯托弗·戈登·阿特伍德 检测生物相关分子及其相互作用性质的方法
EP2474829A1 (en) * 2011-01-07 2012-07-11 Axetris AG Method for determination of molecular structures and functions
WO2012116161A1 (en) 2011-02-23 2012-08-30 The Trustees Of Columbia University In The City Of New York Systems and methods for single-molecule detection using nanopores
WO2012146458A2 (en) 2011-04-26 2012-11-01 Paul Scherrer Institut A method for producing a polymer-based microfluidics system for bioanalytics using biological membranes
KR101569891B1 (ko) * 2012-02-13 2015-11-27 동국대학교 산학협력단 다공성 지지체를 이용한 저분자 포집용 졸-겔 칩 및 이를 이용한 저분자 특이적 물질의 스크리닝 방법
GB201202519D0 (en) * 2012-02-13 2012-03-28 Oxford Nanopore Tech Ltd Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules
GB201313121D0 (en) 2013-07-23 2013-09-04 Oxford Nanopore Tech Ltd Array of volumes of polar medium
GB201300465D0 (en) 2013-01-11 2013-02-27 Aquaporin As A hollow fiber module having tfc-aquaporin modified membranes
DK177696B1 (en) 2013-02-25 2014-03-17 Aquaporin As Systems for water extraction
CN103592433A (zh) * 2013-11-29 2014-02-19 南京祥中生物科技有限公司 一种生物芯片微阵列布点方法
CN103940864B (zh) * 2014-03-25 2016-03-09 西北大学 双管式单分子微流装置
EP3173143A4 (en) * 2014-07-24 2018-06-27 Toppan Printing Co., Ltd. Lipid membrane structure, lipid-membrane-structure-immobilization carrier, and method for fusing cells
GB201611770D0 (en) 2016-07-06 2016-08-17 Oxford Nanopore Tech Microfluidic device
WO2018217419A1 (en) * 2017-05-26 2018-11-29 Quantapore, Inc. Stable lipid bilayers on nanopore arrays
WO2019008736A1 (ja) 2017-07-07 2019-01-10 株式会社日立ハイテクノロジーズ 薄膜デバイス保管装置，保管方法及び生体分子計測方法
CN109709185B (zh) * 2017-10-25 2024-09-24 深圳宣泽生物医药有限公司 一种修饰生物探针的纳米孔检测装置及制作方法
GB2568895B (en) 2017-11-29 2021-10-27 Oxford Nanopore Tech Ltd Microfluidic device
GB2574048B (en) 2018-05-24 2021-06-16 Oxford Nanopore Tech Ltd Nanopore sensor component with electrostatic discharge protection
WO2020183172A1 (en) 2019-03-12 2020-09-17 Oxford Nanopore Technologies Inc. Nanopore sensing device and methods of operation and of forming it
JP7730005B2 (ja) * 2019-05-29 2025-08-27 ナンジン、ユニバーシティ 電極を使用しないナノポアによる分析物の検出
CN115989410A (zh) 2020-07-17 2023-04-18 牛津纳米孔科技公开有限公司 纳米孔感测装置

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011755A1 (en) * 1993-10-28 1995-05-04 Houston Advanced Research Center Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
US5716526A (en) * 1994-01-14 1998-02-10 The Liposome Company, Inc. Method of separating materials from liposomes or lipid complexes
AU2206800A (en) * 1998-12-11 2000-06-26 Regents Of The University Of California, The Targeted molecular bar codes and methods for using the same
US6783643B2 (en) * 1999-06-22 2004-08-31 President And Fellows Of Harvard College Control of solid state dimensional features
US6916665B2 (en) * 2000-02-11 2005-07-12 The Texas A&M University System Biosensor compositions and methods of use
JP4361271B2 (ja) * 2000-10-10 2009-11-11 バイオトローブ・インコーポレイテツド アッセイ、合成、および保存用の器具、ならびに、その作製、使用、および操作の方法
US6818907B2 (en) * 2000-10-17 2004-11-16 The President And Fellows Of Harvard College Surface plasmon enhanced illumination system
JP2002218974A (ja) * 2001-01-24 2002-08-06 Ebara Corp 反応プローブチップ及び検出システム
WO2003016040A1 (en) * 2001-04-16 2003-02-27 The Regents Of The University Of California Membrane mimetic architectures on nanoporous materials
US6785432B2 (en) * 2001-06-15 2004-08-31 The Regents Of The University Of California Target molecules detection by waveguiding in a photonic silicon membrane
DE10142691B4 (de) * 2001-08-31 2006-04-20 Infineon Technologies Ag Verfahren zum Nachweis biochemischer Reaktionen sowie eine Vorrichtung hierfür
US6875671B2 (en) * 2001-09-12 2005-04-05 Reveo, Inc. Method of fabricating vertical integrated circuits
US20050230272A1 (en) * 2001-10-03 2005-10-20 Lee Gil U Porous biosensing device
US20030104512A1 (en) * 2001-11-30 2003-06-05 Freeman Alex R. Biosensors for single cell and multi cell analysis
US20040120854A1 (en) * 2002-04-04 2004-06-24 Heath James R Silicon-wafer based devices and methods for analyzing biological material
US7744816B2 (en) * 2002-05-01 2010-06-29 Intel Corporation Methods and device for biomolecule characterization

Also Published As

Publication number Publication date
JP2007529003A (ja) 2007-10-18
WO2005064342A1 (en) 2005-07-14
EP1697752A1 (en) 2006-09-06
DE602004013042T2 (de) 2009-05-14
EP1697752B1 (en) 2008-04-09
JP4448142B2 (ja) 2010-04-07
US20070275480A1 (en) 2007-11-29
DE602004013042D1 (de) 2008-05-21
US8105820B2 (en) 2012-01-31
EP1548444A1 (en) 2005-06-29
CN1902497A (zh) 2007-01-24
CN1902497B (zh) 2012-08-22
ATE391916T1 (de) 2008-04-15

Similar Documents

Publication Publication Date Title
ATE391916T1 (de) Testchip sowie verwendungen des testchips zur bestimmung molekularer strukturen und funktionen
Funakoshi et al. Lipid bilayer formation by contacting monolayers in a microfluidic device for membrane protein analysis
Su et al. Surface plasmon resonance spectroscopy and quartz crystal microbalance study of streptavidin film structure effects on biotinylated DNA assembly and target DNA hybridization
ES2412887T3 (es) Sensor piezoeléctrico en voladizo de autodetección, autoexcitable
Römer et al. Channel activity of a viral transmembrane peptide in micro-BLMs: Vpu1-32 from HIV-1
SE0403139D0 (sv) Device and use thereof
CA2951945C (en) Apparatuses and methods for determining analyte charge
DE60225058D1 (de) Teststreifen zur bestimmung von triglyceridkonzentrationen
SE0100875D0 (sv) Method of preparing supported lipid film membranes and use thereof
WO2003068947A8 (en) Assay electrodes having immobilized lipid/protein layers and methods of making and using the same
EP2154522A3 (en) Biosensor
EP1390730A4 (en) Integrated thin film liquid conductivity sensor
ATE527543T1 (de) Testvorrichtung zur schnelldiagnose
EA200601753A1 (ru) Синтетические "мембранные якори"
Anna et al. Methods for 20S immunoproteasome and 20S constitutive proteasome determination based on SPRI biosensors
Chen et al. Target-protecting dumbbell molecular probe against exonucleases digestion for sensitive detection of ATP and streptavidin
ATE389177T1 (de) Immobilisierung von bindungsstoffen
Suzuki et al. Ninety-six-well planar lipid bilayer chip for ion channel recording fabricated by hybrid stereolithography
BRPI0416270A (pt) método para detectar um analito em uma amostra, e, método e kit para detectar um anticorpo especìfico de uma amostra
Sikanen et al. Hybrid ceramic polymers: New, nonbiofouling, and optically transparent materials for microfluidics
CN117897501A (zh) 纳米力学可致动核酸纳米孔
ATE367577T1 (de) Optischer biosensor
DE60328359D1 (de) Für den chemilumineszenznachweis optimierte festphasen
DE60138610D1 (de) Teststreifen mit poröser Filterschicht
NO20080908L (no) Stasjonaer stotteseng til rensing, separering, pavising, modifisering og/eller immoblisering av malenheter og fremgangsmater for anvedelse derav