BRPI0416270A - método para detectar um analito em uma amostra, e, método e kit para detectar um anticorpo especìfico de uma amostra - Google Patents

método para detectar um analito em uma amostra, e, método e kit para detectar um anticorpo especìfico de uma amostra

Info

Publication number
BRPI0416270A
BRPI0416270A BRPI0416270-6A BRPI0416270A BRPI0416270A BR PI0416270 A BRPI0416270 A BR PI0416270A BR PI0416270 A BRPI0416270 A BR PI0416270A BR PI0416270 A BRPI0416270 A BR PI0416270A
Authority
BR
Brazil
Prior art keywords
sample
detecting
analyte
detection
binding molecule
Prior art date
Application number
BRPI0416270-6A
Other languages
English (en)
Inventor
David Andrew Anderson
Teresa Sylvia Howard
Original Assignee
Hepgenics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2003906147A external-priority patent/AU2003906147A0/en
Application filed by Hepgenics Pty Ltd filed Critical Hepgenics Pty Ltd
Publication of BRPI0416270A publication Critical patent/BRPI0416270A/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Mathematical Physics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Theoretical Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

"MéTODO PARA DETECTAR UM ANALITO EM UMA AMOSTRA, E, KIT PARA DETECTAR UM ANTICORPO ESPECìFICO DE UMA AMOSTRA". Em uma forma de realização, a presente invenção provê um complexo de detecção, que é útil para detectar um analito específico de interesse em uma amostra. O complexo compreende um marcador de detecção, indiretamente conectado a um parceiro de ligação do analito por um complexo ponte. Este arranjo serve para preservar ou aumentar a disponibilidade dos sítios de ligação do analito no parceiro de ligação do analito e, conseqüentemente, aumentar a detecção do analito. Em algumas formas de realização, a presente invenção provê um completo de detecção útil para detectar um anticorpo específico de interesse em uma amostra. De acordo com um aspecto da presente invenção, são providos métodos para detectar um ou mais anticorpos, empregando-se um complexo ponte compreendendo moléculas ou particulas multiméricas, diméricas ou quiméricas, cada uma compreendendo um antígeno e acoplada a marcadores de detecção, através do uso de anticorpos ou uma molécula de ligação de proteína, molécula de ligação de ácido nucléico, molécula de ligação de carboidrato ou molécula de ligação de lípídeo.
BRPI0416270-6A 2003-11-07 2004-11-05 método para detectar um analito em uma amostra, e, método e kit para detectar um anticorpo especìfico de uma amostra BRPI0416270A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2003906147A AU2003906147A0 (en) 2003-11-07 Binding assay components
PCT/AU2004/001522 WO2005045439A1 (en) 2003-11-07 2004-11-05 Binding assay components

Publications (1)

Publication Number Publication Date
BRPI0416270A true BRPI0416270A (pt) 2007-01-09

Family

ID=34558185

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416270-6A BRPI0416270A (pt) 2003-11-07 2004-11-05 método para detectar um analito em uma amostra, e, método e kit para detectar um anticorpo especìfico de uma amostra

Country Status (6)

Country Link
US (1) US20070298432A1 (pt)
EP (1) EP1692514A4 (pt)
JP (1) JP2007510165A (pt)
CN (1) CN1902496A (pt)
BR (1) BRPI0416270A (pt)
WO (1) WO2005045439A1 (pt)

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* Cited by examiner, † Cited by third party
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FR2917173B1 (fr) * 2007-06-08 2009-07-31 Bio Rad Pasteur Sa Procede multiplexe de detection d'une infection
CN101769928B (zh) * 2008-12-30 2013-10-02 博阳生物科技（上海）有限公司 乙型肝炎病毒核心抗体检测微粒、其制备及应用
DE102011082459B4 (de) 2011-09-09 2013-11-07 Continental Automotive Gmbh Verfahren zur Analyse des Wirkungsgrades der Hochdruckpumpe eines Kraftstoffeinspritzsystems
CN103529213B (zh) * 2013-10-16 2015-07-22 北京华卫骥生物医药有限公司 一种量子点标记免疫层析试纸的制备方法
TWI691716B (zh) * 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
CN104714028B (zh) * 2015-03-02 2017-01-25 深圳市凯瑞德生物技术有限公司 一种检测IgM抗体的免疫检测方法
JP6822973B2 (ja) * 2015-04-17 2021-01-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 凝集の検出方法及びその方法を実施する際に使用する組成物
CN118275398A (zh) 2017-01-30 2024-07-02 硕腾服务有限责任公司 基于溶液的等离子体振子特异性结合配偶体测定和金属纳米结构
SG11202009802WA (en) * 2018-04-03 2020-11-27 The Royal Institution For The Advancement Of Learning/Mcgill Univ Colocalization-by-linkage sandwich assays
CN108872611B (zh) * 2018-05-23 2021-04-02 浙江安吉赛安芙生物科技有限公司 一种胶体金利用标记羊抗鼠二抗后间接连接鼠抗标记的金标免疫层析试纸条的制备方法
CN110818800B (zh) * 2018-08-14 2023-09-15 上海透景诊断科技有限公司 一种通过构建桥连复合物间接检测目的分析物的检测方法
CN115380218A (zh) 2019-10-02 2022-11-22 诺米克生物公司 用于多重化的连接-共定位夹心测定
EP4051102A4 (en) * 2019-10-28 2023-11-22 Genotix Biotechnologies Inc. ANALYTE DETECTION AND QUANTIFICATION THROUGH DISCRETE ENROLLMENT OF PARTICLE COMPLEXES
DE102020107918B4 (de) * 2020-03-23 2021-11-18 Digital Diagnostics AG Detektion von viren
CN116148462B (zh) * 2021-11-22 2025-11-18 菲鹏生物股份有限公司 一种捕获法检测抗体的方法和应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993020445A1 (en) * 1992-03-31 1993-10-14 Abbott Laboratories IMMUNOASSAY FOR DETECTING HCV IgM ANTIBODY
DE19543553B4 (de) * 1995-11-22 2009-04-09 Deutsches Primatenzentrum Gmbh VP-Antigene des JC-Virus
FR2767324B1 (fr) * 1997-08-14 2001-04-06 Pasteur Institut Utilisation de proteines d'enveloppe recombinantes pour le diagnostic du virus de la dengue
TR200102423T2 (tr) * 1998-12-04 2002-02-21 Biogen, Inc. Peptid ligandları yoluyla bağlı birden fazla imünojenik bileşeni olan HBV çekirdek antijeni parçacıkları
EP1035414A3 (de) * 1999-03-05 2004-02-04 Viscum AG Inverser Lectin-Assay (ILA) zur Identifizierung und/oder Quantifizierung einer Kohlenhydrat-Bindeaktivität
US20020155582A1 (en) * 1999-12-23 2002-10-24 Lemon Stanley M. Replication competent hepatitis C virus and methods of use
US20040234542A1 (en) * 2001-05-07 2004-11-25 Xiang-Jin Meng Recombinant orf2 proteins of the swine hepatitis e virus and their use as a vaccine and as a diagnostic reagent for medical and veterinary applications
ATE354681T1 (de) * 2001-08-09 2007-03-15 Idexx Lab Inc Nachweis des virus der viralen rinderdiarrhoe in gewebsproben
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WO2004014220A2 (en) * 2002-08-13 2004-02-19 N-Dia, Inc. Devices and methods for detecting amniotic fluid in vaginal secretions

Also Published As

Publication number Publication date
CN1902496A (zh) 2007-01-24
EP1692514A1 (en) 2006-08-23
WO2005045439A1 (en) 2005-05-19
US20070298432A1 (en) 2007-12-27
JP2007510165A (ja) 2007-04-19
EP1692514A4 (en) 2008-04-09

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.